JP2012509321A5 - - Google Patents

Download PDF

Info

Publication number
JP2012509321A5
JP2012509321A5 JP2011537428A JP2011537428A JP2012509321A5 JP 2012509321 A5 JP2012509321 A5 JP 2012509321A5 JP 2011537428 A JP2011537428 A JP 2011537428A JP 2011537428 A JP2011537428 A JP 2011537428A JP 2012509321 A5 JP2012509321 A5 JP 2012509321A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
compound
ray powder
disintegrant
powder diffraction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011537428A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012509321A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2009/006235 external-priority patent/WO2010059239A2/en
Publication of JP2012509321A publication Critical patent/JP2012509321A/ja
Publication of JP2012509321A5 publication Critical patent/JP2012509321A5/ja
Pending legal-status Critical Current

Links

JP2011537428A 2008-11-21 2009-11-20 癌および他の疾患または障害の処置のための、４−［６−メトキシ−７−（３−ピペリジン−１−イル−プロポキシ）キナゾリン−４−イル］ピペラジン−１−カルボン酸（４−イソプロポキシフェニル）−アミドの乳酸塩およびその薬学的組成物 Pending JP2012509321A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US19988808P 2008-11-21 2008-11-21
US61/199,888 2008-11-21
US21039809P 2009-03-17 2009-03-17
US61/210,398 2009-03-17
PCT/US2009/006235 WO2010059239A2 (en) 2008-11-21 2009-11-20 Lactate salt of 4-(6-methoxy-7-(3-piperidin-1-yl-propoxy)quinazolin-4-yl]piperazine-1-carboxylic acid(4-isopropoxyphenyl)-amide and pharmaceutical compositions thereof for the treatment of cancer and other diseases or disorders

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014193355A Division JP2015017116A (ja) 2008-11-21 2014-09-24 癌および他の疾患または障害の処置のための、４−［６−メトキシ−７−（３−ピペリジン−１−イル−プロポキシ）キナゾリン−４−イル］ピペラジン−１−カルボン酸（４−イソプロポキシフェニル）−アミドの乳酸塩およびその薬学的組成物

Publications (2)

Publication Number Publication Date
JP2012509321A JP2012509321A (ja) 2012-04-19
JP2012509321A5 true JP2012509321A5 (enExample) 2012-12-27

Family

ID=41508688

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2011537428A Pending JP2012509321A (ja) 2008-11-21 2009-11-20 癌および他の疾患または障害の処置のための、４−［６−メトキシ−７−（３−ピペリジン−１−イル−プロポキシ）キナゾリン−４−イル］ピペラジン−１−カルボン酸（４−イソプロポキシフェニル）−アミドの乳酸塩およびその薬学的組成物
JP2014193355A Pending JP2015017116A (ja) 2008-11-21 2014-09-24 癌および他の疾患または障害の処置のための、４−［６−メトキシ−７−（３−ピペリジン−１−イル−プロポキシ）キナゾリン−４−イル］ピペラジン−１−カルボン酸（４−イソプロポキシフェニル）−アミドの乳酸塩およびその薬学的組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014193355A Pending JP2015017116A (ja) 2008-11-21 2014-09-24 癌および他の疾患または障害の処置のための、４−［６−メトキシ−７−（３−ピペリジン−１−イル−プロポキシ）キナゾリン−４−イル］ピペラジン−１−カルボン酸（４−イソプロポキシフェニル）−アミドの乳酸塩およびその薬学的組成物

Country Status (4)

Country Link
US (1) US20100273808A1 (enExample)
EP (1) EP2370417A2 (enExample)
JP (2) JP2012509321A (enExample)
WO (1) WO2010059239A2 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2406389B1 (en) 2009-03-13 2019-05-08 Agios Pharmaceuticals, Inc. Methods and compositions for cell-proliferation-related disorders
CA2944788C (en) 2009-06-29 2023-08-22 Agios Pharmaceuticals, Inc. Compounds, and compositions thereof, which modulate pyruvate kinase m2, and methods of making same
CA2793835C (en) 2009-10-21 2021-07-20 Agios Pharmaceuticals, Inc. Methods and compositions for cell-proliferation-related disorders
KR101873543B1 (ko) 2011-05-03 2018-07-02 아지오스 파마슈티컬스 아이엔씨. 치료에 사용하기 위한 피루베이트 키나아제 활성제
CN102827073A (zh) 2011-06-17 2012-12-19 安吉奥斯医药品有限公司 治疗活性组合物和它们的使用方法
CN102827170A (zh) 2011-06-17 2012-12-19 安吉奥斯医药品有限公司 治疗活性组合物和它们的使用方法
US9474779B2 (en) 2012-01-19 2016-10-25 Agios Pharmaceuticals, Inc. Therapeutically active compositions and their methods of use
HK1213798A1 (zh) 2012-10-15 2016-07-15 安吉奥斯医药品有限公司 治療性化合物和組合物
JP2014129238A (ja) * 2012-12-28 2014-07-10 Lion Corp エトドラク含有固形製剤
CN103058959B (zh) * 2013-01-04 2014-09-10 华东理工大学 一种n-(2-(4-甲基哌嗪-1-基)-5-甲酰苯基)酰胺类化合物及其应用
KR20140096571A (ko) * 2013-01-28 2014-08-06 한미약품 주식회사 1-(4-(4-(3,4-디클로로-2-플루오로페닐아미노)-7-메톡시퀴나졸린-6-일옥시)피페리딘-1-일)프로프-2-엔-1-온의 제조방법
WO2015003355A2 (en) 2013-07-11 2015-01-15 Agios Pharmaceuticals, Inc. Therapeutically active compounds and their methods of use
US9579324B2 (en) 2013-07-11 2017-02-28 Agios Pharmaceuticals, Inc Therapeutically active compounds and their methods of use
WO2015003360A2 (en) 2013-07-11 2015-01-15 Agios Pharmaceuticals, Inc. Therapeutically active compounds and their methods of use
CA2917671A1 (en) 2013-07-11 2015-01-15 Agios Pharmaceuticals, Inc. 2,4-or 4,6-diaminopyrimidine compounds as idh2 mutants inhibitors for the treatment of cancer
US20150031627A1 (en) 2013-07-25 2015-01-29 Agios Pharmaceuticals, Inc Therapeutically active compounds and their methods of use
RS62178B1 (sr) * 2014-03-14 2021-08-31 Les Laboratoires Servier Sas Farmaceutske kompozicije terapeutski aktivnih jedinjenja
CA2942072C (en) 2014-03-14 2022-07-26 Agios Pharmaceuticals, Inc. Pharmaceutical compositions and use of (s)-1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-( 4-cyanopyridin-2-yl)-n-( 5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide
DK3307271T3 (da) 2015-06-11 2023-10-09 Agios Pharmaceuticals Inc Fremgangsmåder til anvendelse af pyruvatkinase-aktivatorer
DK3362066T3 (da) 2015-10-15 2021-11-22 Les Laboratoires Servier Sas Kombinationsterapi til behandling af maligniteter
MA71411A (fr) 2015-10-15 2025-04-30 Les Laboratoires Servier Polythérapie pour le traitement de tumeurs malignes
US10980788B2 (en) 2018-06-08 2021-04-20 Agios Pharmaceuticals, Inc. Therapy for treating malignancies
CN117567449A (zh) 2020-10-13 2024-02-20 勃林格殷格翰国际有限公司 再加工方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU643280B2 (en) 1990-05-25 1993-11-11 Diamond Innovations, Inc. Abrasive compact of cubic boron nitride and method of making same
US5101609A (en) 1991-07-15 1992-04-07 Eastman Kodak Company Cigarette package inspection indexing wheel
JP2753911B2 (ja) * 1991-12-06 1998-05-20 キッセイ薬品工業株式会社 Ｎ−ｔｅｒｔ−ブチル−１−メチル−３，３−ジフェニルプロピルアミン塩酸塩の結晶多形およびその製造方法
JPH05230044A (ja) * 1992-02-21 1993-09-07 Hoechst Japan Ltd ピレタニドの新規な結晶多形
JP3532988B2 (ja) * 1995-02-22 2004-05-31 アベンティス ファーマ株式会社 ピレタニドの新規な結晶多形およびその製造方法
WO1998014431A1 (en) * 1996-10-01 1998-04-09 Kyowa Hakko Kogyo Co., Ltd. Nitrogenous heterocyclic compounds
JP3011904B2 (ja) * 1997-06-10 2000-02-21 明久 井上 金属ガラスの製造方法および装置
ES2356886T3 (es) * 1998-03-31 2011-04-14 Kyowa Hakko Kirin Co., Ltd. Compuestos heterocíclicos nitrogenados.
EP1309568B1 (en) * 2000-08-18 2011-02-16 Millennium Pharmaceuticals, Inc. [(quinazolin-4-yl)piperazin-4-yl]thiocarboxamide compounds as inhibitors of the phosphorylation of a PDGF receptor
MXPA03001359A (es) * 2000-08-18 2004-12-13 Millennium Pharm Inc Derivados de quinazolina como inhibidores de cinasa.
WO2002016362A2 (en) * 2000-08-18 2002-02-28 Cor Therapeutics, Inc. Nitrogenous heterocyclic compounds
ATE502928T1 (de) * 2000-11-01 2011-04-15 Millennium Pharm Inc Stickstoffhaltige heterozyklische verbindungen und verfahren zu deren herstellung
US20040259881A1 (en) * 2001-02-02 2004-12-23 Anjali Pandey Nitrogenous heterocyclic compounds
AU2002254152A1 (en) * 2001-03-08 2002-09-24 Millennium Pharmaceuticals (homo) piperazine substituted quinolines for inhibiting the phosphorylation of kinases
US7058169B2 (en) * 2003-08-27 2006-06-06 D.B. Zwirn Finance, Llc Skill based chat function in a communication system
US7456189B2 (en) * 2003-09-30 2008-11-25 Boehringer Ingelheim International Gmbh Bicyclic heterocycles, medicaments containing these compounds, their use and processes for their preparation
KR101167573B1 (ko) * 2003-11-07 2012-07-30 노바티스 백신즈 앤드 다이아그노스틱스 인코포레이티드 개선된 약학적 성질을 갖는 퀴놀리논 화합물의 약학적으로허용가능한 염
US20060063735A1 (en) * 2004-09-17 2006-03-23 Supergen, Inc. Salts of 5-azacytidine
JP2008519055A (ja) * 2004-11-08 2008-06-05 シャイア エルエルシー ミルタザピンと興奮剤複合物の併用投与の相乗効果
US8110573B2 (en) * 2004-12-30 2012-02-07 Astex Therapeutics Limited Pyrazole compounds that modulate the activity of CDK, GSK and aurora kinases
EP1843769A1 (en) * 2005-01-07 2007-10-17 Pfizer Products Incorporated Fast-disintegrating dosage forms of 5,8,14-triazatetracyclo[10.3.1.02,11.04,9]-hexadeca-2(11),3,5,7,9-pentaene
WO2007012042A1 (en) * 2005-07-20 2007-01-25 Millennium Pharmaceuticals, Inc. New crystal forms of 4-[6-methoxy-7-(3-piperidin-1-yl-propoxy)quinazolin-4-yl]piperazine-1-carboxylic acid(4-isopropoxyphenyl)-amide
DE102005042784A1 (de) 2005-07-26 2007-02-01 Bosch Rexroth Aktiengesellschaft Ventilanordnung und Kühlvorrichtung

Similar Documents

Publication Publication Date Title
JP2012509321A5 (enExample)
AU2019226302B2 (en) Crystalline solid forms of N-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N'-(4-fluorophenyl) cyclopropane-1,1-dicarboxamide, processes for making, and methods of use
AU2021200202B2 (en) Crystalline fumarate salt of (s)-[3,4-difluoro-2-(2-fluoro-4-iodophenylamino)phenyl] [3-hydroxy-3-(piperidin-2-yl) azetidin-1-yl]-methanone
JP2009534373A (ja) 新しい結晶形態のラミブジン
JP2012255038A (ja) 異常な細胞増殖の治療用のピリミジン誘導体
CA2734965A1 (en) Novel crystalline form and processes for its preparation
CN103562183B (zh) 奥米沙班的苯甲酸盐
WO2016116942A1 (en) Novel pharmaceutical compounds comprising ticagrelor with salts of aspirin
JP2023531078A (ja) 化合物の結晶形態
EP2943454A1 (en) Tapentadol maleate and crystalline forms thereof
KR20170023003A (ko) 5-클로로-ｎ-({(5ｓ)-2-옥소-3-[4-(5,6-디하이드로-4h-[1,2,4]트리아진-1-일)페닐]-1,3-옥사졸리딘-5-일}메틸)티오펜-2-카르복사미드 메탄설폰산염의 신규 결정형 및 이를 포함하는 약학 조성물
KR20240093547A (ko) 리나프라잔 글루레이트의 메실레이트 염의 다형체
HK40040786A (en) Crystalline solid forms of n-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-n'-(4-fluorophenyl) cyclopropane-1, 1-dicarboxamide, processes for making, and methods of use