JP2012509321A5 - - Google Patents
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- JP2012509321A5 JP2012509321A5 JP2011537428A JP2011537428A JP2012509321A5 JP 2012509321 A5 JP2012509321 A5 JP 2012509321A5 JP 2011537428 A JP2011537428 A JP 2011537428A JP 2011537428 A JP2011537428 A JP 2011537428A JP 2012509321 A5 JP2012509321 A5 JP 2012509321A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- compound
- ray powder
- disintegrant
- powder diffraction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19988808P | 2008-11-21 | 2008-11-21 | |
| US61/199,888 | 2008-11-21 | ||
| US21039809P | 2009-03-17 | 2009-03-17 | |
| US61/210,398 | 2009-03-17 | ||
| PCT/US2009/006235 WO2010059239A2 (en) | 2008-11-21 | 2009-11-20 | Lactate salt of 4-(6-methoxy-7-(3-piperidin-1-yl-propoxy)quinazolin-4-yl]piperazine-1-carboxylic acid(4-isopropoxyphenyl)-amide and pharmaceutical compositions thereof for the treatment of cancer and other diseases or disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014193355A Division JP2015017116A (ja) | 2008-11-21 | 2014-09-24 | 癌および他の疾患または障害の処置のための、４−［６−メトキシ−７−（３−ピペリジン−１−イル−プロポキシ）キナゾリン−４−イル］ピペラジン−１−カルボン酸（４−イソプロポキシフェニル）−アミドの乳酸塩およびその薬学的組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012509321A JP2012509321A (ja) | 2012-04-19 |
| JP2012509321A5 true JP2012509321A5 (enExample) | 2012-12-27 |
Family
ID=41508688
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011537428A Pending JP2012509321A (ja) | 2008-11-21 | 2009-11-20 | 癌および他の疾患または障害の処置のための、４−［６−メトキシ−７−（３−ピペリジン−１−イル−プロポキシ）キナゾリン−４−イル］ピペラジン−１−カルボン酸（４−イソプロポキシフェニル）−アミドの乳酸塩およびその薬学的組成物 |
| JP2014193355A Pending JP2015017116A (ja) | 2008-11-21 | 2014-09-24 | 癌および他の疾患または障害の処置のための、４−［６−メトキシ−７−（３−ピペリジン−１−イル−プロポキシ）キナゾリン−４−イル］ピペラジン−１−カルボン酸（４−イソプロポキシフェニル）−アミドの乳酸塩およびその薬学的組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014193355A Pending JP2015017116A (ja) | 2008-11-21 | 2014-09-24 | 癌および他の疾患または障害の処置のための、４−［６−メトキシ−７−（３−ピペリジン−１−イル−プロポキシ）キナゾリン−４−イル］ピペラジン−１−カルボン酸（４−イソプロポキシフェニル）−アミドの乳酸塩およびその薬学的組成物 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20100273808A1 (enExample) |
| EP (1) | EP2370417A2 (enExample) |
| JP (2) | JP2012509321A (enExample) |
| WO (1) | WO2010059239A2 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120121515A1 (en) | 2009-03-13 | 2012-05-17 | Lenny Dang | Methods and compositions for cell-proliferation-related disorders |
| TWI598337B (zh) | 2009-06-29 | 2017-09-11 | 阿吉歐斯製藥公司 | 治療化合物及組成物 |
| WO2011050210A1 (en) | 2009-10-21 | 2011-04-28 | Agios Pharmaceuticals, Inc. | Methods and compositions for cell-proliferation-related disorders |
| SMT202400081T1 (it) | 2011-05-03 | 2024-03-13 | Agios Pharmaceuticals Inc | Attivatori della piruvato chinasi per uso in terapia |
| CN102827073A (zh) | 2011-06-17 | 2012-12-19 | 安吉奥斯医药品有限公司 | 治疗活性组合物和它们的使用方法 |
| CN102827170A (zh) | 2011-06-17 | 2012-12-19 | 安吉奥斯医药品有限公司 | 治疗活性组合物和它们的使用方法 |
| US9474779B2 (en) | 2012-01-19 | 2016-10-25 | Agios Pharmaceuticals, Inc. | Therapeutically active compositions and their methods of use |
| EP2906212A4 (en) | 2012-10-15 | 2016-06-08 | Agios Pharmaceuticals Inc | THERAPEUTIC COMPOUNDS AND COMPOSITIONS |
| JP2014129238A (ja) * | 2012-12-28 | 2014-07-10 | Lion Corp | エトドラク含有固形製剤 |
| CN103058959B (zh) * | 2013-01-04 | 2014-09-10 | 华东理工大学 | 一种n-(2-(4-甲基哌嗪-1-基)-5-甲酰苯基)酰胺类化合物及其应用 |
| KR20140096571A (ko) * | 2013-01-28 | 2014-08-06 | 한미약품 주식회사 | 1-(4-(4-(3,4-디클로로-2-플루오로페닐아미노)-7-메톡시퀴나졸린-6-일옥시)피페리딘-1-일)프로프-2-엔-1-온의 제조방법 |
| WO2015003360A2 (en) | 2013-07-11 | 2015-01-15 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| CN105593215B (zh) | 2013-07-11 | 2019-01-15 | 安吉奥斯医药品有限公司 | 用于治疗癌症的作为idh2突变体抑制剂的2,4-或4,6-二氨基嘧啶化合物 |
| WO2015003355A2 (en) | 2013-07-11 | 2015-01-15 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| WO2015010297A1 (en) | 2013-07-25 | 2015-01-29 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| MA39725B1 (fr) * | 2014-03-14 | 2021-09-30 | Les Laboratoires Servier Sas | Compositions pharmaceutiques de composés thérapeutiquement actifs |
| NZ723859A (en) | 2014-03-14 | 2023-01-27 | Servier Lab | Pharmaceutical compositions of therapeutically active compounds and their uses |
| CA2989111C (en) | 2015-06-11 | 2023-10-03 | Agios Pharmaceuticals, Inc. | Methods of using pyruvate kinase activators |
| FI3362065T3 (fi) | 2015-10-15 | 2024-06-19 | Servier Lab | Ivosidenibiä, sytarabiinia ja daunorubisiinia tai idarubisiinia käsittävä yhdistelmähoito akuutin myelooisen leukemian hoitamiseksi |
| KR102699521B1 (ko) | 2015-10-15 | 2024-08-26 | 르 라보레또레 쎄르비에르 | 악성 종양의 치료를 위한 조합물 요법 |
| US10980788B2 (en) | 2018-06-08 | 2021-04-20 | Agios Pharmaceuticals, Inc. | Therapy for treating malignancies |
| IL301829A (en) | 2020-10-13 | 2023-06-01 | Boehringer Ingelheim Int | Process of reworking |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2083693C (en) | 1990-05-25 | 2002-01-01 | Alfred Edward Ringwood | Abrasive compact of cubic boron nitride and method of making same |
| US5101609A (en) | 1991-07-15 | 1992-04-07 | Eastman Kodak Company | Cigarette package inspection indexing wheel |
| JP2753911B2 (ja) * | 1991-12-06 | 1998-05-20 | キッセイ薬品工業株式会社 | Ｎ−ｔｅｒｔ−ブチル−１−メチル−３，３−ジフェニルプロピルアミン塩酸塩の結晶多形およびその製造方法 |
| JPH05230044A (ja) * | 1992-02-21 | 1993-09-07 | Hoechst Japan Ltd | ピレタニドの新規な結晶多形 |
| JP3532988B2 (ja) * | 1995-02-22 | 2004-05-31 | アベンティス ファーマ株式会社 | ピレタニドの新規な結晶多形およびその製造方法 |
| EP0882717B1 (en) * | 1996-10-01 | 2010-09-08 | Kyowa Hakko Kirin Co., Ltd. | Nitrogenous heterocyclic compounds |
| JP3011904B2 (ja) * | 1997-06-10 | 2000-02-21 | 明久 井上 | 金属ガラスの製造方法および装置 |
| EP1067123B1 (en) * | 1998-03-31 | 2011-01-19 | Kyowa Hakko Kirin Co., Ltd. | Nitrogenous heterocyclic compounds |
| PT1315715E (pt) | 2000-08-18 | 2008-10-30 | Millennium Pharm Inc | Derivados de quianazolina utilizados como inibidores de quinase |
| DE60143204D1 (de) * | 2000-08-18 | 2010-11-18 | Kyowa Hakko Kirin Co Ltd | N-aryl-ä4-Ä7-(alkoxy)Chinazolin-4-ylÜPiperazinylüCarboxamid-Verbindungen als PDGF-Rezeptoren Hemmer |
| AU2001293208A1 (en) * | 2000-08-18 | 2002-03-04 | Cor Therapeutics, Inc. | Nitrogenous heterocyclic compounds |
| JP4564713B2 (ja) * | 2000-11-01 | 2010-10-20 | ミレニアム・ファーマシューティカルズ・インコーポレイテッド | 窒素性複素環式化合物、ならびに窒素性複素環式化合物およびその中間体を作製するための方法 |
| US20040259881A1 (en) * | 2001-02-02 | 2004-12-23 | Anjali Pandey | Nitrogenous heterocyclic compounds |
| WO2002072578A2 (en) * | 2001-03-08 | 2002-09-19 | Millennium Pharmaceuticals | (homo) piperazine substituted quinolines for inhibiting the phosphorylation of kinases |
| US7058169B2 (en) * | 2003-08-27 | 2006-06-06 | D.B. Zwirn Finance, Llc | Skill based chat function in a communication system |
| US7456189B2 (en) * | 2003-09-30 | 2008-11-25 | Boehringer Ingelheim International Gmbh | Bicyclic heterocycles, medicaments containing these compounds, their use and processes for their preparation |
| US20050209247A1 (en) * | 2003-11-07 | 2005-09-22 | Chiron Corporation | Pharmaceutically acceptable salts of quinolinone compounds having improved pharmaceutical properties |
| US20060063735A1 (en) * | 2004-09-17 | 2006-03-23 | Supergen, Inc. | Salts of 5-azacytidine |
| JP2008519055A (ja) * | 2004-11-08 | 2008-06-05 | シャイア エルエルシー | ミルタザピンと興奮剤複合物の併用投与の相乗効果 |
| MX2007008008A (es) * | 2004-12-30 | 2007-11-12 | Astex Therapeutics Ltd | Compuestos de pirazol que modulan la actividad de las cinasas cdk, gsk y aurora. |
| WO2006072832A1 (en) * | 2005-01-07 | 2006-07-13 | Pfizer Products Inc. | Fast-disintegrating dosage forms of 5,8,14-triazatetracyclo[10.3.1.02,11.04,9]-hexadeca-2(11),3,5,7,9-pentaene |
| EP1904459A1 (en) * | 2005-07-20 | 2008-04-02 | Millennium Pharmaceuticals, Inc. | New crystal forms of 4-[6-methoxy-7-(3-piperidin-1-yl-propoxy)quinazolin-4-yl]piperazine-1-carboxylic acid(4-isopropoxyphenyl)-amide |
| DE102005042784A1 (de) | 2005-07-26 | 2007-02-01 | Bosch Rexroth Aktiengesellschaft | Ventilanordnung und Kühlvorrichtung |
-
2009
- 2009-11-20 JP JP2011537428A patent/JP2012509321A/ja active Pending
- 2009-11-20 EP EP09771435A patent/EP2370417A2/en not_active Withdrawn
- 2009-11-20 WO PCT/US2009/006235 patent/WO2010059239A2/en not_active Ceased
- 2009-11-20 US US12/622,617 patent/US20100273808A1/en not_active Abandoned
-
2014
- 2014-09-24 JP JP2014193355A patent/JP2015017116A/ja active Pending
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