JP2012509083A5 - - Google Patents
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- JP2012509083A5 JP2012509083A5 JP2011537585A JP2011537585A JP2012509083A5 JP 2012509083 A5 JP2012509083 A5 JP 2012509083A5 JP 2011537585 A JP2011537585 A JP 2011537585A JP 2011537585 A JP2011537585 A JP 2011537585A JP 2012509083 A5 JP2012509083 A5 JP 2012509083A5
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- Prior art keywords
- biopolymer
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- 238000000034 method Methods 0.000 claims description 46
- 108020004414 DNA Proteins 0.000 claims description 12
- 108020004707 nucleic acids Proteins 0.000 claims description 9
- 102000039446 nucleic acids Human genes 0.000 claims description 9
- 150000007523 nucleic acids Chemical class 0.000 claims description 9
- 239000002773 nucleotide Substances 0.000 claims 34
- 125000003729 nucleotide group Chemical group 0.000 claims 34
- 229920001222 biopolymer Polymers 0.000 claims 24
- 239000000523 sample Substances 0.000 claims 21
- 239000007850 fluorescent dye Substances 0.000 claims 17
- 238000003776 cleavage reaction Methods 0.000 claims 12
- 230000007017 scission Effects 0.000 claims 12
- 102000053602 DNA Human genes 0.000 claims 8
- 230000001678 irradiating effect Effects 0.000 claims 8
- 239000000975 dye Substances 0.000 claims 7
- 102000004533 Endonucleases Human genes 0.000 claims 5
- 108010042407 Endonucleases Proteins 0.000 claims 5
- 108700024394 Exon Proteins 0.000 claims 3
- 230000005284 excitation Effects 0.000 claims 3
- 230000000295 complement effect Effects 0.000 claims 2
- 238000002372 labelling Methods 0.000 claims 2
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 238000004458 analytical method Methods 0.000 description 2
- 241000424725 Heide Species 0.000 description 1
- 108060003951 Immunoglobulin Proteins 0.000 description 1
- 206010025323 Lymphomas Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 101100264172 Oryza sativa subsp. japonica XIAO gene Proteins 0.000 description 1
- 108091036333 Rapid DNA Proteins 0.000 description 1
- 241000700584 Simplexvirus Species 0.000 description 1
- 230000001594 aberrant effect Effects 0.000 description 1
- LXQXZNRPTYVCNG-UHFFFAOYSA-N americium atom Chemical compound [Am] LXQXZNRPTYVCNG-UHFFFAOYSA-N 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 210000003719 b-lymphocyte Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 102000018358 immunoglobulin Human genes 0.000 description 1
- 238000007901 in situ hybridization Methods 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 238000013507 mapping Methods 0.000 description 1
- 238000004452 microanalysis Methods 0.000 description 1
- 230000009826 neoplastic cell growth Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000003753 real-time PCR Methods 0.000 description 1
- 230000008707 rearrangement Effects 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
- 238000004557 single molecule detection Methods 0.000 description 1
- 238000010200 validation analysis Methods 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11570408P | 2008-11-18 | 2008-11-18 | |
| US61/115,704 | 2008-11-18 | ||
| PCT/US2009/064996 WO2010059731A2 (en) | 2008-11-18 | 2009-11-18 | Polynucleotide mapping and sequencing |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012509083A JP2012509083A (ja) | 2012-04-19 |
| JP2012509083A5 true JP2012509083A5 (https=) | 2013-01-10 |
| JP5846703B2 JP5846703B2 (ja) | 2016-01-20 |
Family
ID=41820235
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011537585A Active JP5846703B2 (ja) | 2008-11-18 | 2009-11-18 | ポリヌクレオチドのマッピング及び配列決定 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9181578B2 (https=) |
| EP (1) | EP2370594B1 (https=) |
| JP (1) | JP5846703B2 (https=) |
| CN (3) | CN104372080B (https=) |
| AU (1) | AU2009316628B2 (https=) |
| CA (1) | CA2744064C (https=) |
| SG (1) | SG171325A1 (https=) |
| WO (1) | WO2010059731A2 (https=) |
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| HUE042654T2 (hu) | 2013-06-21 | 2019-07-29 | Sequenom Inc | Eljárás genetikai variációk nem-invazív megállapítására |
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| EP4355870A1 (en) * | 2021-06-18 | 2024-04-24 | Drexel University | Multicolor whole-genome mapping and sequencing in nanochannel for genetic analysis |
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- 2009-11-18 AU AU2009316628A patent/AU2009316628B2/en active Active
- 2009-11-18 CN CN200980154567.1A patent/CN102292454B/zh active Active
- 2009-11-18 US US13/129,634 patent/US9181578B2/en active Active
- 2009-11-18 CA CA2744064A patent/CA2744064C/en active Active
- 2009-11-18 WO PCT/US2009/064996 patent/WO2010059731A2/en not_active Ceased
- 2009-11-18 SG SG2011035508A patent/SG171325A1/en unknown
- 2009-11-18 JP JP2011537585A patent/JP5846703B2/ja active Active
- 2009-11-18 CN CN201810153810.9A patent/CN108467887A/zh active Pending
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2015
- 2015-10-07 US US14/877,818 patent/US10000803B2/en active Active
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