JP2012505892A - Ｍｍｐ−１３阻害剤として有用な縮合ヘテロアリールジアミド化合物 - Google Patents
Ｍｍｐ−１３阻害剤として有用な縮合ヘテロアリールジアミド化合物 Download PDFInfo
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- JP2012505892A JP2012505892A JP2011532177A JP2011532177A JP2012505892A JP 2012505892 A JP2012505892 A JP 2012505892A JP 2011532177 A JP2011532177 A JP 2011532177A JP 2011532177 A JP2011532177 A JP 2011532177A JP 2012505892 A JP2012505892 A JP 2012505892A
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| US10545508P | 2008-10-15 | 2008-10-15 | |
| US61/105,455 | 2008-10-15 | ||
| PCT/US2009/060439 WO2010045190A1 (en) | 2008-10-15 | 2009-10-13 | Fused heteroaryl diamide compounds useful as mmp-13 inhibitors |
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| JP2012505892A true JP2012505892A (ja) | 2012-03-08 |
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| WO2010045190A1 (en) | 2008-10-15 | 2010-04-22 | Boehringer Ingelheim International Gmbh | Fused heteroaryl diamide compounds useful as mmp-13 inhibitors |
| EP2340243B1 (en) | 2008-10-17 | 2014-10-08 | Boehringer Ingelheim International GmbH | Heteroaryl substituted indole compounds useful as mmp-13 inhibitors |
| US8637550B2 (en) | 2008-11-17 | 2014-01-28 | Boehringer Ingelheim International Gmbh | Heteroaryl diamide compounds useful as MMP-13 inhibitors |
| RU2013114352A (ru) | 2010-09-15 | 2014-10-20 | Ф. Хоффманн-Ля Рош Аг | Азабензотиазолы, композиции и способы применения |
| AR086113A1 (es) | 2011-04-30 | 2013-11-20 | Abbott Lab | Isoxazolinas como agentes terapeuticos |
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| AU2164300A (en) | 1998-12-04 | 2000-06-26 | N.V. Organon | Substituted thiazoles for treatment of human diseases involving modulators of p-, l- and e- selectin |
| US20020165222A1 (en) * | 1999-02-19 | 2002-11-07 | Smithkline Beecham Corporation | Protease inhibitors |
| EA200100972A1 (ru) | 1999-03-15 | 2002-02-28 | Аксис Фармасьютикалз, Инк. | Новые соединения и композиции как ингибиторы протеаз |
| GB0018758D0 (en) | 2000-07-31 | 2000-09-20 | Smithkline Beecham Plc | Novel use and compunds |
| HUP0302966A2 (hu) | 2000-07-31 | 2003-12-29 | Smithkline Beecham P.L.C. | Karboxamid-vegyületek és alkalmazásuk humán 11CBY receptor antagonistákként, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények |
| WO2002016348A1 (en) | 2000-08-09 | 2002-02-28 | Astrazeneca Ab | Antiangiogenic bicyclic derivatives |
| DE10229070A1 (de) | 2002-06-28 | 2004-01-15 | Merck Patent Gmbh | Phenylderivate 5 |
| US20050004111A1 (en) * | 2003-01-03 | 2005-01-06 | Aventis Pharma Deutschland Gmbh | Selective MMP-13 inhibitors |
| KR20060079190A (ko) | 2003-08-14 | 2006-07-05 | 아사히 가세이 파마 가부시키가이샤 | 치환 아릴알칸산 유도체 및 그의 용도 |
| US20080275028A1 (en) | 2004-07-20 | 2008-11-06 | Giovanni Gaviraghi | Modulators or Alpha7 Nicotinic Acetylcholine Receptors and Therapeutic Uses Thereof |
| EP1838690A2 (en) | 2004-12-21 | 2007-10-03 | Devgen N.V. | Compounds with kv4 ion channel activity |
| GT200600042A (es) | 2005-02-10 | 2006-09-27 | Aventis Pharma Inc | Compuestos de bis arilo y heteroarilo sustituido como antagonistas selectivos de 5ht2a |
| MX2008001778A (es) | 2005-08-19 | 2008-04-07 | Aventis Pharma Inc | Combinacion de un agente hipnotico y un compuesto de bis arilo y heteroarilo sustituido y aplicacion terapeutica de la misma. |
| WO2010045190A1 (en) | 2008-10-15 | 2010-04-22 | Boehringer Ingelheim International Gmbh | Fused heteroaryl diamide compounds useful as mmp-13 inhibitors |
| EP2340243B1 (en) | 2008-10-17 | 2014-10-08 | Boehringer Ingelheim International GmbH | Heteroaryl substituted indole compounds useful as mmp-13 inhibitors |
| US8637550B2 (en) | 2008-11-17 | 2014-01-28 | Boehringer Ingelheim International Gmbh | Heteroaryl diamide compounds useful as MMP-13 inhibitors |
-
2009
- 2009-10-13 WO PCT/US2009/060439 patent/WO2010045190A1/en not_active Ceased
- 2009-10-13 EP EP09740587A patent/EP2344480A1/en not_active Withdrawn
- 2009-10-13 CA CA2739488A patent/CA2739488A1/en not_active Abandoned
- 2009-10-13 US US13/123,002 patent/US8338367B2/en active Active
- 2009-10-13 JP JP2011532177A patent/JP2012505892A/ja not_active Withdrawn
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| Publication number | Publication date |
|---|---|
| WO2010045190A1 (en) | 2010-04-22 |
| US20110269668A1 (en) | 2011-11-03 |
| US8338367B2 (en) | 2012-12-25 |
| EP2344480A1 (en) | 2011-07-20 |
| CA2739488A1 (en) | 2010-04-22 |
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