JP2012505151A5 - - Google Patents

Download PDF

Info

Publication number
JP2012505151A5
JP2012505151A5 JP2010528222A JP2010528222A JP2012505151A5 JP 2012505151 A5 JP2012505151 A5 JP 2012505151A5 JP 2010528222 A JP2010528222 A JP 2010528222A JP 2010528222 A JP2010528222 A JP 2010528222A JP 2012505151 A5 JP2012505151 A5 JP 2012505151A5
Authority
JP
Japan
Prior art keywords
bmp
polypeptide
seq
promoter
canine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010528222A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012505151A (ja
Filing date
Publication date
Priority claimed from US11/867,919 external-priority patent/US7846428B2/en
Application filed filed Critical
Publication of JP2012505151A publication Critical patent/JP2012505151A/ja
Publication of JP2012505151A5 publication Critical patent/JP2012505151A5/ja
Pending legal-status Critical Current

Links

JP2010528222A 2007-10-05 2008-10-07 Bmp−7をコードする組換えベクターを用いる関節軟骨の遺伝子治療 Pending JP2012505151A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/867,919 US7846428B2 (en) 2007-10-05 2007-10-05 Articular cartilage gene therapy with recombinant vector encoding BMP-7
PCT/US2008/079090 WO2009046464A1 (en) 2007-10-05 2008-10-07 Articular cartilage gene therapy with recombinant vector encoding bmp-7

Publications (2)

Publication Number Publication Date
JP2012505151A JP2012505151A (ja) 2012-03-01
JP2012505151A5 true JP2012505151A5 (enExample) 2012-04-12

Family

ID=40276182

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010528222A Pending JP2012505151A (ja) 2007-10-05 2008-10-07 Bmp−7をコードする組換えベクターを用いる関節軟骨の遺伝子治療

Country Status (7)

Country Link
US (1) US7846428B2 (enExample)
EP (1) EP2205743B1 (enExample)
JP (1) JP2012505151A (enExample)
CN (1) CN102027114A (enExample)
BR (1) BRPI0817753A8 (enExample)
CA (1) CA2701215C (enExample)
WO (1) WO2009046464A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2784861A1 (en) * 2009-12-21 2011-07-14 Pharmathene, Inc. Recombinant butyrylcholinesterases and truncates thereof
RU2516951C1 (ru) * 2013-03-01 2014-05-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Мордовский государственный университет им. Н.П. Огарёва" Способ профилактики посттравматического артроза коленного сустава
SI3021873T1 (sl) * 2013-07-18 2018-12-31 Xalud Therapeutics, Inc. Sestavek za zdravljenje vnetne sklepne bolezni
EP4786600A2 (en) * 2013-09-09 2026-08-05 FibroBiologics, Inc. Gene therapy for the regeneration of chondrocytes or cartilage type cells
MX381665B (es) 2016-01-13 2025-03-13 Genzyme Corp Star Vectores aav recombinantes que expresan genes osteoprotectores, que incluyen has2 y lubricina, de utilidad en el tratamiento de la osteoartritis y afecciones articulares relacionadas en mamiferos.
CN109310734B (zh) * 2016-04-13 2022-06-24 马斯特里赫特大学 骨关节炎的治疗或预防方法
CN110997708A (zh) 2017-04-27 2020-04-10 礼来公司 人bmp7蛋白的变体
CN109496152B (zh) * 2018-05-17 2021-06-18 广州蓝亮医药科技有限公司 癸氧喹酯组合物的肌肉内库存及其预防和治疗的方法
CN112168793A (zh) * 2020-10-26 2021-01-05 辰欣药业股份有限公司 一种盐酸氨溴索口腔崩解片及其制备方法
EP4333903A4 (en) * 2021-05-03 2025-03-19 North Carolina State University COMPOSITIONS AND METHODS RELATED TO THE TREATMENT OF OPHTHALMIC DISEASES IN HORSES

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5266683A (en) * 1988-04-08 1993-11-30 Stryker Corporation Osteogenic proteins
US6159464A (en) * 1990-12-20 2000-12-12 University Of Pittsburgh Of The Commonwealth System Of Higher Education Viral vectors to inhibit leukocyte infiltration or cartilage degradation of joints
AU2002311777A1 (en) * 2001-04-17 2002-10-28 Genetix Pharmaceuticals, Inc. Method of treating arthritis using lentiviral vectors in gene therapy
US20040167088A1 (en) * 2003-02-25 2004-08-26 Genvec, Inc. Method of using adenoviral vectors with increased persistence in vivo
US20040223953A1 (en) * 2003-03-17 2004-11-11 Hsiang-Fu Kung Combined adeno-associated virus and adenovirus cocktail gene delivery system for high efficiency gene expression without eliciting immune response in immuno-competent subjects
WO2005007098A2 (en) * 2003-07-08 2005-01-27 New York University Nucleic acid therapy to enhance cartilage repair
EP1660663A4 (en) * 2003-08-12 2007-07-11 Brigham & Womens Hospital METHOD AND COMPOSITIONS FOR TISSUE REPAIR
EP1951751B1 (en) 2005-11-14 2017-11-01 Merial, Inc. Gene therapy for renal failure
ATE543833T1 (de) * 2005-12-22 2012-02-15 Janssen Biotech Inc Bmp-7-varianten-zusammensetzungen, verfahren und verwendungen

Similar Documents

Publication Publication Date Title
JP2009515529A5 (enExample)
Schmelzer et al. Elastic fibers: formation, function, and fate during aging and disease
Ogawa et al. Osteoactivin upregulates expression of MMP-3 and MMP-9 in fibroblasts infiltrated into denervated skeletal muscle in mice
US20180009869A1 (en) Fusion Protein Comprising Leptin and Methods for Producing and Using the Same
AU2025203706A9 (en) Recombinant collagen and elastin molecules and uses thereof
JP4201253B2 (ja) 薬学的活性物質に潜在性を提供する方法
TWI710570B (zh) 用於治療代謝異常之組成物及方法
TWI642682B (zh) 升糖素類似物
JP2001523465A (ja) 単鎖二官能性糖タンパク質ホルモン
JP2009544279A5 (enExample)
CS91791A3 (en) Epithelium or epithelium precursors
JP2009545313A5 (enExample)
AU2002219345A1 (en) Latency associated peptide for providing latency to pharmaceutically active proteins
Wijffels et al. A novel family of chitin-binding proteins from insect type 2 peritrophic matrix: cDNA sequences, chitin binding activity, and cellular localization
US20200062814A1 (en) Modified Latency Associated Protein Construct
Hossain et al. H3 relaxin demonstrates antifibrotic properties via the RXFP1 receptor
US11952602B2 (en) Variants of porcine trypsin
DE69926627T2 (de) Insulinartigen wachstumsfaktor bindendes protein -3 variante
WO2009046464A8 (en) Articular cartilage gene therapy with recombinant vector encoding bmp-7
EP1764106A2 (en) Use of insulin-like growth factor I for the inhibition of ischemic injury involving the liver
US20090269843A1 (en) Hemopexin fusion proteins
US8703733B2 (en) Humanized TTC and methods of use thereof
JP2025507929A5 (enExample)
JP2022024242A (ja) 標的ポリペプチド分解誘導剤
JP2025540675A (ja) オクタデカニューロペプチド(odn)およびその合成誘導体を含む組成物、ならびに食物摂取、肥満、体重、吐き気および嘔吐の調節のための使用方法