JP2012504958A5 - - Google Patents
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- Publication number
- JP2012504958A5 JP2012504958A5 JP2011530980A JP2011530980A JP2012504958A5 JP 2012504958 A5 JP2012504958 A5 JP 2012504958A5 JP 2011530980 A JP2011530980 A JP 2011530980A JP 2011530980 A JP2011530980 A JP 2011530980A JP 2012504958 A5 JP2012504958 A5 JP 2012504958A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- protein
- aureus
- seq
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 43
- 102000004196 processed proteins & peptides Human genes 0.000 claims 41
- 229920001184 polypeptide Polymers 0.000 claims 40
- 108090000623 proteins and genes Proteins 0.000 claims 19
- 102000004169 proteins and genes Human genes 0.000 claims 19
- 239000008194 pharmaceutical composition Substances 0.000 claims 18
- 239000012634 fragment Substances 0.000 claims 17
- 230000000844 anti-bacterial effect Effects 0.000 claims 16
- 150000001413 amino acids Chemical group 0.000 claims 15
- 101710126949 Lysin Proteins 0.000 claims 10
- 239000003814 drug Substances 0.000 claims 10
- 102000039446 nucleic acids Human genes 0.000 claims 10
- 108020004707 nucleic acids Proteins 0.000 claims 10
- 150000007523 nucleic acids Chemical class 0.000 claims 10
- 229940124597 therapeutic agent Drugs 0.000 claims 10
- 238000000034 method Methods 0.000 claims 8
- 241000191940 Staphylococcus Species 0.000 claims 6
- 230000000694 effects Effects 0.000 claims 6
- 230000008685 targeting Effects 0.000 claims 6
- 239000013598 vector Substances 0.000 claims 6
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 5
- 241000894006 Bacteria Species 0.000 claims 5
- 239000003937 drug carrier Substances 0.000 claims 5
- 239000002773 nucleotide Substances 0.000 claims 5
- 125000003729 nucleotide group Chemical group 0.000 claims 5
- 208000035143 Bacterial infection Diseases 0.000 claims 4
- 208000022362 bacterial infectious disease Diseases 0.000 claims 4
- 230000003197 catalytic effect Effects 0.000 claims 4
- 241000191967 Staphylococcus aureus Species 0.000 claims 3
- 238000012216 screening Methods 0.000 claims 3
- 241000193830 Bacillus <bacterium> Species 0.000 claims 2
- 241000194033 Enterococcus Species 0.000 claims 2
- 241000192041 Micrococcus Species 0.000 claims 2
- 230000003115 biocidal effect Effects 0.000 claims 2
- 239000013604 expression vector Substances 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 238000009630 liquid culture Methods 0.000 claims 2
- 241000192125 Firmicutes Species 0.000 claims 1
- 230000000845 anti-microbial effect Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10459408P | 2008-10-10 | 2008-10-10 | |
| US61/104,594 | 2008-10-10 | ||
| PCT/PT2009/000051 WO2010041970A2 (en) | 2008-10-10 | 2009-10-09 | Antibacterial phage peptides and methods of use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012504958A JP2012504958A (ja) | 2012-03-01 |
| JP2012504958A5 true JP2012504958A5 (enExample) | 2012-11-29 |
| JP5732397B2 JP5732397B2 (ja) | 2015-06-10 |
Family
ID=41818594
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011530980A Expired - Fee Related JP5732397B2 (ja) | 2008-10-10 | 2009-10-09 | 抗菌性ファージペプチド及びその使用法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8563504B2 (enExample) |
| EP (2) | EP2571984A2 (enExample) |
| JP (1) | JP5732397B2 (enExample) |
| AU (1) | AU2009302985B2 (enExample) |
| CA (1) | CA2739717A1 (enExample) |
| SG (1) | SG189733A1 (enExample) |
| WO (1) | WO2010041970A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2307557B1 (en) * | 2008-07-03 | 2017-03-01 | The Rockefeller University | A chimeric bacteriophage lysin with activity against staphylococci bacteria |
| CN102348460B (zh) | 2009-02-06 | 2015-08-26 | 抗菌技术,生物技术研究与发展股份有限公司 | 抗菌噬菌体、噬菌体肽及其使用方法 |
| PT104837A (pt) | 2009-11-24 | 2011-05-24 | Technophage Investiga O E Desenvolvimento Em Biotecnologia S A | P?ptidos de fagos enteroc?cicos e m?todos para a sua utiliza??o |
| JP6058540B2 (ja) | 2010-09-17 | 2017-01-11 | テクニファー−インダストリア テクニカ ファーマシューティカ，エス．エー． | 抗菌性ファージ、ファージペプチド、及びそれらの使用方法 |
| CN104780933B (zh) * | 2012-05-09 | 2020-08-28 | 康特拉费克特公司 | 使用噬菌体溶素的生物膜预防、破坏和处理 |
| CN104805066B (zh) * | 2015-05-18 | 2018-04-24 | 武汉菲吉乐科生物科技有限公司 | 一种葡萄球菌裂解酶及其应用 |
| AU2017371484B2 (en) | 2016-12-05 | 2022-09-15 | Technophage, Investigação e Desenvolvimento Em Biotecnologia SA | Bacteriophage compositions comprising respiratory antibacterial phages and methods of use thereof |
| KR102131692B1 (ko) * | 2018-09-11 | 2020-07-08 | 경북대학교 산학협력단 | 병원성 세균을 효과적으로 사멸시키는 재조합 항균 효소 LysSAP26의 용도 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| DE69220397T2 (de) * | 1991-03-13 | 1997-10-02 | Morinaga Milk Industry Co Ltd | Antimikrobielles Peptid und antimikrobieller Wirkstoff |
| US5863560A (en) | 1996-09-11 | 1999-01-26 | Virotex Corporation | Compositions and methods for topical application of therapeutic agents |
| GB0107661D0 (en) * | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
| WO2004020635A1 (ja) | 2002-08-28 | 2004-03-11 | Techno Network Shikoku Co., Ltd. | バクテリオファージおよび細菌感染症治療剤 |
| ES2536852T3 (es) * | 2006-05-05 | 2015-05-28 | Gangagen, Inc. | Actividades antimicrobianas derivadas de fagos |
| DE102006061002A1 (de) * | 2006-12-22 | 2008-06-26 | Profos Ag | Verfahren und Mittel zur Anreicherung, Entfernung und zum Nachweis von gram-positiven Bakterien |
-
2009
- 2009-10-09 EP EP09752498A patent/EP2571984A2/en not_active Withdrawn
- 2009-10-09 EP EP14166479.7A patent/EP2899268A1/en not_active Withdrawn
- 2009-10-09 SG SG2013024476A patent/SG189733A1/en unknown
- 2009-10-09 US US13/122,190 patent/US8563504B2/en not_active Expired - Fee Related
- 2009-10-09 CA CA2739717A patent/CA2739717A1/en not_active Abandoned
- 2009-10-09 WO PCT/PT2009/000051 patent/WO2010041970A2/en not_active Ceased
- 2009-10-09 JP JP2011530980A patent/JP5732397B2/ja not_active Expired - Fee Related
- 2009-10-09 AU AU2009302985A patent/AU2009302985B2/en not_active Ceased
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