CA2739717A1 - Antibacterial phage peptides and methods of use thereof - Google Patents

Antibacterial phage peptides and methods of use thereof Download PDF

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Publication number
CA2739717A1
CA2739717A1 CA2739717A CA2739717A CA2739717A1 CA 2739717 A1 CA2739717 A1 CA 2739717A1 CA 2739717 A CA2739717 A CA 2739717A CA 2739717 A CA2739717 A CA 2739717A CA 2739717 A1 CA2739717 A1 CA 2739717A1
Authority
CA
Canada
Prior art keywords
polypeptide
aureus
protein
chimeric
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2739717A
Other languages
English (en)
French (fr)
Inventor
Miguel Angelo Da Costa Garcia
Madalena Maria Vilela Pimentel
Carlos Jorge Sousa De São Jose
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lusomedicamenta SA
Original Assignee
Lusomedicamenta SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lusomedicamenta SA filed Critical Lusomedicamenta SA
Publication of CA2739717A1 publication Critical patent/CA2739717A1/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/503Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/10011Details dsDNA Bacteriophages
    • C12N2795/10311Siphoviridae
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/10011Details dsDNA Bacteriophages
    • C12N2795/10311Siphoviridae
    • C12N2795/10322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA2739717A 2008-10-10 2009-10-09 Antibacterial phage peptides and methods of use thereof Abandoned CA2739717A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10459408P 2008-10-10 2008-10-10
US61/104,594 2008-10-10
PCT/PT2009/000051 WO2010041970A2 (en) 2008-10-10 2009-10-09 Antibacterial phage peptides and methods of use thereof

Publications (1)

Publication Number Publication Date
CA2739717A1 true CA2739717A1 (en) 2010-04-15

Family

ID=41818594

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2739717A Abandoned CA2739717A1 (en) 2008-10-10 2009-10-09 Antibacterial phage peptides and methods of use thereof

Country Status (7)

Country Link
US (1) US8563504B2 (enExample)
EP (2) EP2899268A1 (enExample)
JP (1) JP5732397B2 (enExample)
AU (1) AU2009302985B2 (enExample)
CA (1) CA2739717A1 (enExample)
SG (1) SG189733A1 (enExample)
WO (1) WO2010041970A2 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2729160C (en) * 2008-07-03 2017-11-14 The Rockefeller University A chimeric bacteriophage lysin with activity against staphylococci bacteria
US9134312B2 (en) * 2009-02-06 2015-09-15 Tecnifar—Industria Tecnica Farmaceutica, S.A. Antibacterial phage, phage peptides and methods of use thereof
PT104837A (pt) 2009-11-24 2011-05-24 Technophage Investiga O E Desenvolvimento Em Biotecnologia S A P?ptidos de fagos enteroc?cicos e m?todos para a sua utiliza??o
ES2825050T3 (es) * 2010-09-17 2021-05-14 Tecnifar Ind Tecnica Farmaceutica S A Fago antibacteriano, péptidos de fago y métodos de uso de los mismos
RU2646102C2 (ru) 2012-05-09 2018-03-01 Контрафект Корпорейшн Предотвращение, разрушение и обработка биопленки лизином бактериофага
CN104805066B (zh) * 2015-05-18 2018-04-24 武汉菲吉乐科生物科技有限公司 一种葡萄球菌裂解酶及其应用
JP7154543B2 (ja) 2016-12-05 2022-10-18 テクノファージ インヴェスティガサォン エ デセンヴォルヴィメント エム ビオテクノロジア エスィアー 呼吸器抗菌性ファージを含むバクテリオファージ組成物、およびその使用法
KR102131692B1 (ko) * 2018-09-11 2020-07-08 경북대학교 산학협력단 병원성 세균을 효과적으로 사멸시키는 재조합 항균 효소 LysSAP26의 용도

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5807715A (en) 1984-08-27 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
NZ241936A (en) * 1991-03-13 1994-03-25 Morinaga Milk Industry Co Ltd Antimicrobial peptide and its use in an antimicrobial composition
US5863560A (en) 1996-09-11 1999-01-26 Virotex Corporation Compositions and methods for topical application of therapeutic agents
GB0107661D0 (en) * 2001-03-27 2001-05-16 Chiron Spa Staphylococcus aureus
AU2003261782A1 (en) * 2002-08-28 2004-03-19 Techno Network Shikoku Co., Ltd. Bacteriophages and remedies for bacterial infection
JP5383481B2 (ja) * 2006-05-05 2014-01-08 ガンガゲン インコーポレーテッド ファージに由来する抗微生物活性
DE102006061002A1 (de) * 2006-12-22 2008-06-26 Profos Ag Verfahren und Mittel zur Anreicherung, Entfernung und zum Nachweis von gram-positiven Bakterien

Also Published As

Publication number Publication date
AU2009302985B2 (en) 2015-09-10
JP2012504958A (ja) 2012-03-01
EP2571984A2 (en) 2013-03-27
SG189733A1 (en) 2013-05-31
WO2010041970A2 (en) 2010-04-15
US20110230393A1 (en) 2011-09-22
US8563504B2 (en) 2013-10-22
JP5732397B2 (ja) 2015-06-10
WO2010041970A3 (en) 2010-09-10
AU2009302985A1 (en) 2010-04-15
EP2899268A1 (en) 2015-07-29

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20141007

FZDE Discontinued

Effective date: 20180306