AU2009302985B2 - Antibacterial phage peptides and methods of use thereof - Google Patents

Antibacterial phage peptides and methods of use thereof Download PDF

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Publication number
AU2009302985B2
AU2009302985B2 AU2009302985A AU2009302985A AU2009302985B2 AU 2009302985 B2 AU2009302985 B2 AU 2009302985B2 AU 2009302985 A AU2009302985 A AU 2009302985A AU 2009302985 A AU2009302985 A AU 2009302985A AU 2009302985 B2 AU2009302985 B2 AU 2009302985B2
Authority
AU
Australia
Prior art keywords
polypeptide
aureus
seq
chimeric
fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2009302985A
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English (en)
Other versions
AU2009302985A1 (en
Inventor
Miguel Angelo Da Costa Garcia
Carlos Jorge Sousa De Sao Jose
Madalena Maria Vilela Pimentel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lusomedicamenta SA
Original Assignee
Lusomedicamenta SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lusomedicamenta SA filed Critical Lusomedicamenta SA
Publication of AU2009302985A1 publication Critical patent/AU2009302985A1/en
Application granted granted Critical
Publication of AU2009302985B2 publication Critical patent/AU2009302985B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10311—Siphoviridae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10311—Siphoviridae
    • C12N2795/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2009302985A 2008-10-10 2009-10-09 Antibacterial phage peptides and methods of use thereof Ceased AU2009302985B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10459408P 2008-10-10 2008-10-10
US61/104,594 2008-10-10
PCT/PT2009/000051 WO2010041970A2 (en) 2008-10-10 2009-10-09 Antibacterial phage peptides and methods of use thereof

Publications (2)

Publication Number Publication Date
AU2009302985A1 AU2009302985A1 (en) 2010-04-15
AU2009302985B2 true AU2009302985B2 (en) 2015-09-10

Family

ID=41818594

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009302985A Ceased AU2009302985B2 (en) 2008-10-10 2009-10-09 Antibacterial phage peptides and methods of use thereof

Country Status (7)

Country Link
US (1) US8563504B2 (enExample)
EP (2) EP2899268A1 (enExample)
JP (1) JP5732397B2 (enExample)
AU (1) AU2009302985B2 (enExample)
CA (1) CA2739717A1 (enExample)
SG (1) SG189733A1 (enExample)
WO (1) WO2010041970A2 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010002959A2 (en) * 2008-07-03 2010-01-07 The Rockefeller University A chimeric bacteriophage lysin with activity against staphylococci bacteria
ES2761835T3 (es) * 2009-02-06 2020-05-21 Technophage Investig E Desenvolvimento Em Biotecnologia Sa Fagos antibacterianos, péptidos de fagos y métodos de uso de los mismos
PT104837A (pt) 2009-11-24 2011-05-24 Technophage Investiga O E Desenvolvimento Em Biotecnologia S A P?ptidos de fagos enteroc?cicos e m?todos para a sua utiliza??o
RU2614114C2 (ru) 2010-09-17 2017-03-22 Текнифар-Индустриа Текника Фармасьютика, С.А Бактериофаги, фаговые пептиды и способы их применения
RU2646102C2 (ru) * 2012-05-09 2018-03-01 Контрафект Корпорейшн Предотвращение, разрушение и обработка биопленки лизином бактериофага
CN104805066B (zh) * 2015-05-18 2018-04-24 武汉菲吉乐科生物科技有限公司 一种葡萄球菌裂解酶及其应用
WO2018106135A2 (en) 2016-12-05 2018-06-14 Technophage, Investigação E Desenvolvimento Em Biotecnologia, Sa Bacteriophage compositions comprising respiratory antibacterial phages and methods of use thereof
KR102131692B1 (ko) 2018-09-11 2020-07-08 경북대학교 산학협력단 병원성 세균을 효과적으로 사멸시키는 재조합 항균 효소 LysSAP26의 용도

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060115490A1 (en) * 2001-03-27 2006-06-01 Vega Masignani Staphylococcus aureus proteins and nucleic acids

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5807715A (en) 1984-08-27 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
DE69220397T2 (de) * 1991-03-13 1997-10-02 Morinaga Milk Industry Co Ltd Antimikrobielles Peptid und antimikrobieller Wirkstoff
US5863560A (en) 1996-09-11 1999-01-26 Virotex Corporation Compositions and methods for topical application of therapeutic agents
JPWO2004020635A1 (ja) * 2002-08-28 2005-12-15 株式会社テクノネットワーク四国 バクテリオファージおよび細菌感染症治療剤
CN103436507B (zh) * 2006-05-05 2016-04-20 冈戈根股份有限公司 噬菌体衍生的抗微生物活性剂
DE102006061002A1 (de) * 2006-12-22 2008-06-26 Profos Ag Verfahren und Mittel zur Anreicherung, Entfernung und zum Nachweis von gram-positiven Bakterien

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060115490A1 (en) * 2001-03-27 2006-06-01 Vega Masignani Staphylococcus aureus proteins and nucleic acids

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Derwent DWPI Online Abstract Accession No. 2004-239200, WO 2004/020635 A1 *

Also Published As

Publication number Publication date
CA2739717A1 (en) 2010-04-15
EP2899268A1 (en) 2015-07-29
US20110230393A1 (en) 2011-09-22
JP2012504958A (ja) 2012-03-01
JP5732397B2 (ja) 2015-06-10
US8563504B2 (en) 2013-10-22
WO2010041970A3 (en) 2010-09-10
WO2010041970A2 (en) 2010-04-15
EP2571984A2 (en) 2013-03-27
SG189733A1 (en) 2013-05-31
AU2009302985A1 (en) 2010-04-15

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired