JP2012500092A5 - - Google Patents
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- Publication number
- JP2012500092A5 JP2012500092A5 JP2011523892A JP2011523892A JP2012500092A5 JP 2012500092 A5 JP2012500092 A5 JP 2012500092A5 JP 2011523892 A JP2011523892 A JP 2011523892A JP 2011523892 A JP2011523892 A JP 2011523892A JP 2012500092 A5 JP2012500092 A5 JP 2012500092A5
- Authority
- JP
- Japan
- Prior art keywords
- nitric oxide
- oxygen
- kit
- enriched air
- breaths
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 claims 36
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 14
- 239000001301 oxygen Substances 0.000 claims 14
- 229910052760 oxygen Inorganic materials 0.000 claims 14
- 239000007789 gas Substances 0.000 claims 7
- 241000124008 Mammalia Species 0.000 claims 5
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 4
- 239000003963 antioxidant agent Substances 0.000 claims 4
- 230000003078 antioxidant effect Effects 0.000 claims 4
- 235000006708 antioxidants Nutrition 0.000 claims 4
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims 4
- 230000001225 therapeutic effect Effects 0.000 claims 3
- 229940087168 alpha tocopherol Drugs 0.000 claims 2
- 235000010323 ascorbic acid Nutrition 0.000 claims 2
- 239000011668 ascorbic acid Substances 0.000 claims 2
- 229960005070 ascorbic acid Drugs 0.000 claims 2
- 235000010382 gamma-tocopherol Nutrition 0.000 claims 2
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims 2
- 229960000984 tocofersolan Drugs 0.000 claims 2
- 235000004835 α-tocopherol Nutrition 0.000 claims 2
- 239000002076 α-tocopherol Substances 0.000 claims 2
- 239000002478 γ-tocopherol Substances 0.000 claims 2
- QUEDXNHFTDJVIY-DQCZWYHMSA-N γ-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1 QUEDXNHFTDJVIY-DQCZWYHMSA-N 0.000 claims 2
- MGWGWNFMUOTEHG-UHFFFAOYSA-N 4-(3,5-dimethylphenyl)-1,3-thiazol-2-amine Chemical compound CC1=CC(C)=CC(C=2N=C(N)SC=2)=C1 MGWGWNFMUOTEHG-UHFFFAOYSA-N 0.000 claims 1
- 239000011149 active material Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- JCXJVPUVTGWSNB-UHFFFAOYSA-N nitrogen dioxide Inorganic materials O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 claims 1
- 230000029058 respiratory gaseous exchange Effects 0.000 claims 1
- 229920006395 saturated elastomer Polymers 0.000 claims 1
- 238000011287 therapeutic dose Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9062808P | 2008-08-21 | 2008-08-21 | |
| US61/090,628 | 2008-08-21 | ||
| US12/541,148 | 2009-08-13 | ||
| US12/541,148 US10960168B2 (en) | 2008-08-21 | 2009-08-13 | Delivery of high concentration nitric oxide |
| PCT/US2009/053947 WO2010021943A1 (en) | 2008-08-21 | 2009-08-14 | Delivery of high concentration nitric oxide |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014249597A Division JP2015091334A (ja) | 2008-08-21 | 2014-12-10 | 高濃度一酸化窒素の送達 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012500092A JP2012500092A (ja) | 2012-01-05 |
| JP2012500092A5 true JP2012500092A5 (https=) | 2013-02-28 |
Family
ID=41707416
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011523892A Pending JP2012500092A (ja) | 2008-08-21 | 2009-08-14 | 高濃度一酸化窒素の送達 |
| JP2014249597A Pending JP2015091334A (ja) | 2008-08-21 | 2014-12-10 | 高濃度一酸化窒素の送達 |
| JP2017075034A Active JP6518284B2 (ja) | 2008-08-21 | 2017-04-05 | 高濃度一酸化窒素の送達 |
| JP2019021435A Pending JP2019088879A (ja) | 2008-08-21 | 2019-02-08 | 高濃度一酸化窒素の送達 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014249597A Pending JP2015091334A (ja) | 2008-08-21 | 2014-12-10 | 高濃度一酸化窒素の送達 |
| JP2017075034A Active JP6518284B2 (ja) | 2008-08-21 | 2017-04-05 | 高濃度一酸化窒素の送達 |
| JP2019021435A Pending JP2019088879A (ja) | 2008-08-21 | 2019-02-08 | 高濃度一酸化窒素の送達 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10960168B2 (https=) |
| EP (1) | EP2323719B1 (https=) |
| JP (4) | JP2012500092A (https=) |
| AU (1) | AU2009282987B2 (https=) |
| CA (1) | CA2734727A1 (https=) |
| WO (1) | WO2010021943A1 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7523752B2 (en) | 2005-09-21 | 2009-04-28 | Ino Therapeutics, Llc | System and method of administering a pharmaceutical gas to a patient |
| US8893717B2 (en) | 2005-09-21 | 2014-11-25 | Ino Therapeutics Llc | Systems and methods of administering a pharmaceutical gas to a patient |
| US9649467B2 (en) | 2008-01-31 | 2017-05-16 | Syk Technologies, Llc | Nitric oxide reactor and distributor apparatus and method |
| US10960168B2 (en) * | 2008-08-21 | 2021-03-30 | Vero Biotech LLC | Delivery of high concentration nitric oxide |
| USD632782S1 (en) * | 2008-12-08 | 2011-02-15 | Margarita Aguilo-Pinedo | Liquid medication container and oral dispenser |
| EP2619131B1 (en) * | 2010-09-22 | 2019-04-03 | Koninklijke Philips N.V. | Method and arrangement for generating oxygen and nitric oxide. |
| AU2011336358B2 (en) | 2010-12-03 | 2016-09-29 | VERO Biotech LLC. | Nitric oxide treatments |
| BR112013020994A2 (pt) * | 2011-02-21 | 2018-07-10 | Koninklijke Philips Nv | método para a geração de um fluxo de gás e montagem para prover um fluxo de gás |
| JP2014527025A (ja) | 2011-05-27 | 2014-10-09 | ゲノ エルエルシー | 吸入用一酸化窒素を用いて血管反応性を決定する方法 |
| WO2013138654A1 (en) * | 2012-03-15 | 2013-09-19 | Ino Therapeutics Llc | Methods of administering high concentrations of nitric oxide |
| US10517817B2 (en) | 2013-05-09 | 2019-12-31 | Syk Technologies, Llc | Deep topical systemic nitric oxide therapy apparatus and method |
| WO2015157524A1 (en) * | 2014-04-09 | 2015-10-15 | 12th Man Technologies, Inc. | Systems and methods for high concentration nitric oxide delivery |
| WO2017132275A1 (en) | 2016-01-27 | 2017-08-03 | Syk Technologies, Llc | Nitric oxide topical application apparatus and methods |
| MX2020010523A (es) | 2017-02-27 | 2021-02-09 | Third Pole Inc | Sistemas y metodos para generar oxido nitrico. |
| RU2717525C1 (ru) | 2017-02-27 | 2020-03-23 | Сёрд Поул, Инк. | Системы и способы получения оксида азота |
| US10328228B2 (en) | 2017-02-27 | 2019-06-25 | Third Pole, Inc. | Systems and methods for ambulatory generation of nitric oxide |
| US11672938B1 (en) | 2018-07-18 | 2023-06-13 | Vero Biotech LLC | Start-up protocols for nitric oxide delivery device |
| US11754538B1 (en) * | 2018-07-18 | 2023-09-12 | Vero Biotech Inc. | Method and apparatus for automatic calibration |
| EP3969416A4 (en) | 2019-05-15 | 2023-11-01 | Third Pole, Inc. | SYSTEMS AND DEVICES FOR GENERATING NITROGEN OXIDE |
| EP3969016A4 (en) | 2019-05-15 | 2023-08-16 | Third Pole, Inc. | ARCHITECTURES FOR THE PRODUCTION OF NITROUS OXIDE |
| JP2022533628A (ja) | 2019-05-15 | 2022-07-25 | サード ポール，インコーポレイテッド | 一酸化窒素生成用電極 |
| USD998783S1 (en) * | 2019-11-27 | 2023-09-12 | Reciprocal Labs Corporation | Semi-integrated sensor monitor for attachment to an inhaler |
| US11691879B2 (en) | 2020-01-11 | 2023-07-04 | Third Pole, Inc. | Systems and methods for nitric oxide generation with humidity control |
| US20210395905A1 (en) | 2020-06-18 | 2021-12-23 | Third Pole, Inc. | Systems and methods for preventing and treating infections with nitric oxide |
| WO2022082072A1 (en) | 2020-10-16 | 2022-04-21 | Third Pole, Inc. | Nitric oxide generation process controls |
| US11975139B2 (en) | 2021-09-23 | 2024-05-07 | Third Pole, Inc. | Systems and methods for delivering nitric oxide |
| US12569628B2 (en) | 2022-04-14 | 2026-03-10 | Third Pole, Inc. | Delivery of medicinal gas in a liquid medium |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992010228A1 (en) | 1990-12-05 | 1992-06-25 | The General Hospital Corporation | Devices for treating pulmonary vasoconstriction and asthma |
| US5570683A (en) * | 1990-12-05 | 1996-11-05 | The General Hospital Corporation | Methods and devices for treating pulmonary vasoconstriction and asthma |
| FR2695831B1 (fr) * | 1992-09-24 | 1994-11-10 | Air Liquide | Installation et procédé de fourniture d'un mélange gazeux aux voies respiratoires d'un utilisateur. |
| JPH10179742A (ja) | 1996-12-25 | 1998-07-07 | Sumitomo Seika Chem Co Ltd | 携帯用一酸化窒素−酸素ガス供給装置およびその操作方法 |
| US20020185126A1 (en) * | 1997-01-17 | 2002-12-12 | Christian Krebs | Controlled gas-supply system |
| US5918596A (en) * | 1997-04-22 | 1999-07-06 | Instrumentarium Corp. | Special gas dose delivery apparatus for respiration equipment |
| US6142147A (en) * | 1998-03-31 | 2000-11-07 | The General Hospital Corporation | Nasal delivery system for inhaled nitric oxide |
| US6089229A (en) | 1998-05-26 | 2000-07-18 | Datex-Ohmeda, Inc. | High concentration no pulse delivery device |
| JP2000079166A (ja) | 1998-09-07 | 2000-03-21 | Teijin Ltd | 呼吸用気体供給装置 |
| US7516742B2 (en) * | 1999-11-24 | 2009-04-14 | Cardinal Health 207, Inc. | Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients with intermittent dosing |
| US6581599B1 (en) * | 1999-11-24 | 2003-06-24 | Sensormedics Corporation | Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients |
| JP3720032B2 (ja) | 2003-01-21 | 2005-11-24 | 株式会社アプティック | 高気圧式酸素供給装置及びそれに用いるチャンバ |
| AU2005244078A1 (en) * | 2004-05-11 | 2005-11-24 | Pulmonox Technologies Corporation | Intermittent dosing of nitric oxide gas |
| US7618594B2 (en) * | 2004-08-18 | 2009-11-17 | Geno Llc | Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) |
| AU2005277397B2 (en) * | 2004-08-18 | 2011-08-25 | VERO Biotech LLC. | Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) |
| WO2006090260A1 (en) | 2005-02-28 | 2006-08-31 | Pulmonox Technologies Corporation | Means and method for supplying therapeutic gas to a spontaneously breathing patient |
| US7909031B2 (en) * | 2005-06-09 | 2011-03-22 | Temple Univesity - Of The Commonwealth System of Higher Education | Process for transient and steady state delivery of biological agents to the lung via breathable liquids |
| US7523752B2 (en) | 2005-09-21 | 2009-04-28 | Ino Therapeutics, Llc | System and method of administering a pharmaceutical gas to a patient |
| US20080183566A1 (en) * | 2007-01-26 | 2008-07-31 | Montgomery John R | Episodic show, device and system operable to produce a promotional effect |
| US20080193566A1 (en) * | 2007-02-09 | 2008-08-14 | Miller Christopher C | Use of high dose concentrations of gaseous nitric oxide |
| US8434475B2 (en) * | 2008-01-31 | 2013-05-07 | Genosys, Inc. | Nitric oxide reactor and distributor apparatus and method |
| US10960168B2 (en) | 2008-08-21 | 2021-03-30 | Vero Biotech LLC | Delivery of high concentration nitric oxide |
| US10780241B2 (en) | 2008-08-21 | 2020-09-22 | Vero Biotech LLC | Devices and methods for minimizing and treating high-altitude sickness |
-
2009
- 2009-08-13 US US12/541,148 patent/US10960168B2/en active Active
- 2009-08-14 JP JP2011523892A patent/JP2012500092A/ja active Pending
- 2009-08-14 CA CA2734727A patent/CA2734727A1/en not_active Abandoned
- 2009-08-14 EP EP09808648.1A patent/EP2323719B1/en active Active
- 2009-08-14 AU AU2009282987A patent/AU2009282987B2/en not_active Ceased
- 2009-08-14 WO PCT/US2009/053947 patent/WO2010021943A1/en not_active Ceased
-
2014
- 2014-12-10 JP JP2014249597A patent/JP2015091334A/ja active Pending
-
2017
- 2017-04-05 JP JP2017075034A patent/JP6518284B2/ja active Active
-
2019
- 2019-02-08 JP JP2019021435A patent/JP2019088879A/ja active Pending
-
2021
- 2021-03-29 US US17/215,827 patent/US20220016379A1/en not_active Abandoned
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