CA2734727A1 - Delivery of high concentration nitric oxide - Google Patents

Delivery of high concentration nitric oxide Download PDF

Info

Publication number
CA2734727A1
CA2734727A1 CA2734727A CA2734727A CA2734727A1 CA 2734727 A1 CA2734727 A1 CA 2734727A1 CA 2734727 A CA2734727 A CA 2734727A CA 2734727 A CA2734727 A CA 2734727A CA 2734727 A1 CA2734727 A1 CA 2734727A1
Authority
CA
Canada
Prior art keywords
nitric oxide
oxygen
delivery
breaths
mammal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2734727A
Other languages
English (en)
French (fr)
Inventor
David Fine
Lee Leichter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vero Biotech Inc
Original Assignee
Geno LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geno LLC filed Critical Geno LLC
Publication of CA2734727A1 publication Critical patent/CA2734727A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/12—Preparation of respiratory gases or vapours by mixing different gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/04—Nitro compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/008—Electronic counters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007—Mechanical counters
    • A61M15/0071—Mechanical counters having a display or indicator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0208—Oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0266—Nitrogen (N)
    • A61M2202/0275—Nitric oxide [NO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8218—Gas operated
    • A61M2205/8225—Gas operated using incorporated gas cartridges for the driving gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8218—Gas operated
    • A61M2205/8231—Gas operated using electrochemical gas generating device for the driving gas

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CA2734727A 2008-08-21 2009-08-14 Delivery of high concentration nitric oxide Abandoned CA2734727A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US9062808P 2008-08-21 2008-08-21
US61/090,628 2008-08-21
US12/541,148 2009-08-13
US12/541,148 US10960168B2 (en) 2008-08-21 2009-08-13 Delivery of high concentration nitric oxide
PCT/US2009/053947 WO2010021943A1 (en) 2008-08-21 2009-08-14 Delivery of high concentration nitric oxide

Publications (1)

Publication Number Publication Date
CA2734727A1 true CA2734727A1 (en) 2010-02-25

Family

ID=41707416

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2734727A Abandoned CA2734727A1 (en) 2008-08-21 2009-08-14 Delivery of high concentration nitric oxide

Country Status (6)

Country Link
US (2) US10960168B2 (https=)
EP (1) EP2323719B1 (https=)
JP (4) JP2012500092A (https=)
AU (1) AU2009282987B2 (https=)
CA (1) CA2734727A1 (https=)
WO (1) WO2010021943A1 (https=)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7523752B2 (en) 2005-09-21 2009-04-28 Ino Therapeutics, Llc System and method of administering a pharmaceutical gas to a patient
US8893717B2 (en) 2005-09-21 2014-11-25 Ino Therapeutics Llc Systems and methods of administering a pharmaceutical gas to a patient
US9649467B2 (en) 2008-01-31 2017-05-16 Syk Technologies, Llc Nitric oxide reactor and distributor apparatus and method
US10960168B2 (en) * 2008-08-21 2021-03-30 Vero Biotech LLC Delivery of high concentration nitric oxide
USD632782S1 (en) * 2008-12-08 2011-02-15 Margarita Aguilo-Pinedo Liquid medication container and oral dispenser
EP2619131B1 (en) * 2010-09-22 2019-04-03 Koninklijke Philips N.V. Method and arrangement for generating oxygen and nitric oxide.
AU2011336358B2 (en) 2010-12-03 2016-09-29 VERO Biotech LLC. Nitric oxide treatments
BR112013020994A2 (pt) * 2011-02-21 2018-07-10 Koninklijke Philips Nv método para a geração de um fluxo de gás e montagem para prover um fluxo de gás
JP2014527025A (ja) 2011-05-27 2014-10-09 ゲノ エルエルシー 吸入用一酸化窒素を用いて血管反応性を決定する方法
WO2013138654A1 (en) * 2012-03-15 2013-09-19 Ino Therapeutics Llc Methods of administering high concentrations of nitric oxide
US10517817B2 (en) 2013-05-09 2019-12-31 Syk Technologies, Llc Deep topical systemic nitric oxide therapy apparatus and method
WO2015157524A1 (en) * 2014-04-09 2015-10-15 12th Man Technologies, Inc. Systems and methods for high concentration nitric oxide delivery
WO2017132275A1 (en) 2016-01-27 2017-08-03 Syk Technologies, Llc Nitric oxide topical application apparatus and methods
MX2020010523A (es) 2017-02-27 2021-02-09 Third Pole Inc Sistemas y metodos para generar oxido nitrico.
RU2717525C1 (ru) 2017-02-27 2020-03-23 Сёрд Поул, Инк. Системы и способы получения оксида азота
US10328228B2 (en) 2017-02-27 2019-06-25 Third Pole, Inc. Systems and methods for ambulatory generation of nitric oxide
US11672938B1 (en) 2018-07-18 2023-06-13 Vero Biotech LLC Start-up protocols for nitric oxide delivery device
US11754538B1 (en) * 2018-07-18 2023-09-12 Vero Biotech Inc. Method and apparatus for automatic calibration
EP3969416A4 (en) 2019-05-15 2023-11-01 Third Pole, Inc. SYSTEMS AND DEVICES FOR GENERATING NITROGEN OXIDE
EP3969016A4 (en) 2019-05-15 2023-08-16 Third Pole, Inc. ARCHITECTURES FOR THE PRODUCTION OF NITROUS OXIDE
JP2022533628A (ja) 2019-05-15 2022-07-25 サード ポール，インコーポレイテッド 一酸化窒素生成用電極
USD998783S1 (en) * 2019-11-27 2023-09-12 Reciprocal Labs Corporation Semi-integrated sensor monitor for attachment to an inhaler
US11691879B2 (en) 2020-01-11 2023-07-04 Third Pole, Inc. Systems and methods for nitric oxide generation with humidity control
US20210395905A1 (en) 2020-06-18 2021-12-23 Third Pole, Inc. Systems and methods for preventing and treating infections with nitric oxide
WO2022082072A1 (en) 2020-10-16 2022-04-21 Third Pole, Inc. Nitric oxide generation process controls
US11975139B2 (en) 2021-09-23 2024-05-07 Third Pole, Inc. Systems and methods for delivering nitric oxide
US12569628B2 (en) 2022-04-14 2026-03-10 Third Pole, Inc. Delivery of medicinal gas in a liquid medium

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992010228A1 (en) 1990-12-05 1992-06-25 The General Hospital Corporation Devices for treating pulmonary vasoconstriction and asthma
US5570683A (en) * 1990-12-05 1996-11-05 The General Hospital Corporation Methods and devices for treating pulmonary vasoconstriction and asthma
FR2695831B1 (fr) * 1992-09-24 1994-11-10 Air Liquide Installation et procédé de fourniture d'un mélange gazeux aux voies respiratoires d'un utilisateur.
JPH10179742A (ja) 1996-12-25 1998-07-07 Sumitomo Seika Chem Co Ltd 携帯用一酸化窒素−酸素ガス供給装置およびその操作方法
US20020185126A1 (en) * 1997-01-17 2002-12-12 Christian Krebs Controlled gas-supply system
US5918596A (en) * 1997-04-22 1999-07-06 Instrumentarium Corp. Special gas dose delivery apparatus for respiration equipment
US6142147A (en) * 1998-03-31 2000-11-07 The General Hospital Corporation Nasal delivery system for inhaled nitric oxide
US6089229A (en) 1998-05-26 2000-07-18 Datex-Ohmeda, Inc. High concentration no pulse delivery device
JP2000079166A (ja) 1998-09-07 2000-03-21 Teijin Ltd 呼吸用気体供給装置
US7516742B2 (en) * 1999-11-24 2009-04-14 Cardinal Health 207, Inc. Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients with intermittent dosing
US6581599B1 (en) * 1999-11-24 2003-06-24 Sensormedics Corporation Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients
JP3720032B2 (ja) 2003-01-21 2005-11-24 株式会社アプティック 高気圧式酸素供給装置及びそれに用いるチャンバ
AU2005244078A1 (en) * 2004-05-11 2005-11-24 Pulmonox Technologies Corporation Intermittent dosing of nitric oxide gas
US7618594B2 (en) * 2004-08-18 2009-11-17 Geno Llc Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
AU2005277397B2 (en) * 2004-08-18 2011-08-25 VERO Biotech LLC. Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
WO2006090260A1 (en) 2005-02-28 2006-08-31 Pulmonox Technologies Corporation Means and method for supplying therapeutic gas to a spontaneously breathing patient
US7909031B2 (en) * 2005-06-09 2011-03-22 Temple Univesity - Of The Commonwealth System of Higher Education Process for transient and steady state delivery of biological agents to the lung via breathable liquids
US7523752B2 (en) 2005-09-21 2009-04-28 Ino Therapeutics, Llc System and method of administering a pharmaceutical gas to a patient
US20080183566A1 (en) * 2007-01-26 2008-07-31 Montgomery John R Episodic show, device and system operable to produce a promotional effect
US20080193566A1 (en) * 2007-02-09 2008-08-14 Miller Christopher C Use of high dose concentrations of gaseous nitric oxide
US8434475B2 (en) * 2008-01-31 2013-05-07 Genosys, Inc. Nitric oxide reactor and distributor apparatus and method
US10960168B2 (en) 2008-08-21 2021-03-30 Vero Biotech LLC Delivery of high concentration nitric oxide
US10780241B2 (en) 2008-08-21 2020-09-22 Vero Biotech LLC Devices and methods for minimizing and treating high-altitude sickness

Also Published As

Publication number Publication date
EP2323719B1 (en) 2019-03-13
JP2012500092A (ja) 2012-01-05
US20100089392A1 (en) 2010-04-15
EP2323719A4 (en) 2012-08-15
AU2009282987B2 (en) 2016-03-10
WO2010021943A1 (en) 2010-02-25
JP6518284B2 (ja) 2019-05-22
EP2323719A1 (en) 2011-05-25
JP2019088879A (ja) 2019-06-13
US10960168B2 (en) 2021-03-30
JP2015091334A (ja) 2015-05-14
US20220016379A1 (en) 2022-01-20
AU2009282987A1 (en) 2010-02-25
JP2017136423A (ja) 2017-08-10

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20140522

FZDE Discontinued

Effective date: 20220907