JP2012232948A5 - - Google Patents
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- Publication number
- JP2012232948A5 JP2012232948A5 JP2011103593A JP2011103593A JP2012232948A5 JP 2012232948 A5 JP2012232948 A5 JP 2012232948A5 JP 2011103593 A JP2011103593 A JP 2011103593A JP 2011103593 A JP2011103593 A JP 2011103593A JP 2012232948 A5 JP2012232948 A5 JP 2012232948A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- seq
- morphine
- cdr
- variable region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229960005181 morphine Drugs 0.000 claims 23
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Natural products O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 claims 19
- 108090000765 processed proteins & peptides Proteins 0.000 claims 19
- 125000003275 alpha amino acid group Chemical group 0.000 claims 17
- 229920001184 polypeptide Polymers 0.000 claims 15
- 102000004196 processed proteins & peptides Human genes 0.000 claims 15
- 239000012634 fragment Substances 0.000 claims 12
- 108091003079 Bovine Serum Albumin Proteins 0.000 claims 11
- 229940098773 bovine serum albumin Drugs 0.000 claims 11
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims 6
- 150000001413 amino acids Chemical class 0.000 claims 5
- 102000004169 proteins and genes Human genes 0.000 claims 5
- 108090000623 proteins and genes Proteins 0.000 claims 5
- ZPUCINDJVBIVPJ-LJISPDSOSA-N cocaine Chemical compound O([C@H]1C[C@@H]2CC[C@@H](N2C)[C@H]1C(=O)OC)C(=O)C1=CC=CC=C1 ZPUCINDJVBIVPJ-LJISPDSOSA-N 0.000 claims 4
- OROGSEYTTFOCAN-DNJOTXNNSA-N codeine Chemical compound C([C@H]1[C@H](N(CC[C@@]112)C)C3)=C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC OROGSEYTTFOCAN-DNJOTXNNSA-N 0.000 claims 4
- BWGNESOTFCXPMA-UHFFFAOYSA-N Dihydrogen disulfide Chemical compound SS BWGNESOTFCXPMA-UHFFFAOYSA-N 0.000 claims 3
- 108010054477 Immunoglobulin Fab Fragments Proteins 0.000 claims 3
- 102000001706 Immunoglobulin Fab Fragments Human genes 0.000 claims 3
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 3
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 3
- 238000006471 dimerization reaction Methods 0.000 claims 3
- 241000588724 Escherichia coli Species 0.000 claims 2
- GVGLGOZIDCSQPN-PVHGPHFFSA-N Heroin Chemical compound O([C@H]1[C@H](C=C[C@H]23)OC(C)=O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4OC(C)=O GVGLGOZIDCSQPN-PVHGPHFFSA-N 0.000 claims 2
- YQEZLKZALYSWHR-UHFFFAOYSA-N Ketamine Chemical compound C=1C=CC=C(Cl)C=1C1(NC)CCCCC1=O YQEZLKZALYSWHR-UHFFFAOYSA-N 0.000 claims 2
- 241001465754 Metazoa Species 0.000 claims 2
- 229960003920 cocaine Drugs 0.000 claims 2
- 229960004126 codeine Drugs 0.000 claims 2
- 229960002069 diamorphine Drugs 0.000 claims 2
- OROGSEYTTFOCAN-UHFFFAOYSA-N hydrocodone Natural products C1C(N(CCC234)C)C2C=CC(O)C3OC2=C4C1=CC=C2OC OROGSEYTTFOCAN-UHFFFAOYSA-N 0.000 claims 2
- 229960003299 ketamine Drugs 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 241001515965 unidentified phage Species 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 1
- 230000003053 immunization Effects 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 230000000717 retained effect Effects 0.000 claims 1
- 210000004989 spleen cell Anatomy 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011103593A JP2012232948A (ja) | 2011-05-06 | 2011-05-06 | 抗モルヒネ抗体、抗モルヒネ抗体を用いたモルヒネの測定方法、および抗モルヒネ抗体を含むモルヒネ測定キット |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011103593A JP2012232948A (ja) | 2011-05-06 | 2011-05-06 | 抗モルヒネ抗体、抗モルヒネ抗体を用いたモルヒネの測定方法、および抗モルヒネ抗体を含むモルヒネ測定キット |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012232948A JP2012232948A (ja) | 2012-11-29 |
| JP2012232948A5 true JP2012232948A5 (enExample) | 2014-05-15 |
Family
ID=47433650
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011103593A Pending JP2012232948A (ja) | 2011-05-06 | 2011-05-06 | 抗モルヒネ抗体、抗モルヒネ抗体を用いたモルヒネの測定方法、および抗モルヒネ抗体を含むモルヒネ測定キット |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2012232948A (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2702002C1 (ru) * | 2018-07-23 | 2019-10-03 | Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт особо чистых биопрепаратов" Федерального медико-биологического агентства | Моноклональное антитело 3к11 к производным морфина |
| CN117659201B (zh) * | 2022-08-23 | 2024-09-24 | 东莞市朋志生物科技有限公司 | 抗可卡因抗体或其功能性片段、检测可卡因的试剂和试剂盒 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0286794A (ja) * | 1988-09-21 | 1990-03-27 | Ube Ind Ltd | モルヒネに対するモノクローナル抗体およびそのモノクローナル抗体の製法 |
-
2011
- 2011-05-06 JP JP2011103593A patent/JP2012232948A/ja active Pending
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