JP2012105660A5 - - Google Patents
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- Publication number
- JP2012105660A5 JP2012105660A5 JP2012014665A JP2012014665A JP2012105660A5 JP 2012105660 A5 JP2012105660 A5 JP 2012105660A5 JP 2012014665 A JP2012014665 A JP 2012014665A JP 2012014665 A JP2012014665 A JP 2012014665A JP 2012105660 A5 JP2012105660 A5 JP 2012105660A5
- Authority
- JP
- Japan
- Prior art keywords
- odorant receptor
- odorant
- cell
- cell line
- receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000012547 Olfactory receptors Human genes 0.000 claims 27
- 108050002069 Olfactory receptors Proteins 0.000 claims 27
- 210000004027 cell Anatomy 0.000 claims 9
- 238000000034 method Methods 0.000 claims 9
- 150000001875 compounds Chemical class 0.000 claims 6
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 4
- 230000004807 localization Effects 0.000 claims 4
- 150000007523 nucleic acids Chemical group 0.000 claims 4
- 229920001184 polypeptide Polymers 0.000 claims 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims 4
- 102000004196 processed proteins & peptides Human genes 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 210000003370 receptor cell Anatomy 0.000 claims 4
- 210000000170 cell membrane Anatomy 0.000 claims 3
- 230000001737 promoting effect Effects 0.000 claims 3
- 230000000694 effects Effects 0.000 claims 2
- 239000003446 ligand Substances 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 1
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58108704P | 2004-06-18 | 2004-06-18 | |
| US60/581,087 | 2004-06-18 | ||
| US58201104P | 2004-06-22 | 2004-06-22 | |
| US60/582,011 | 2004-06-22 | ||
| US11/156,516 | 2005-06-20 | ||
| US11/156,516 US7425445B2 (en) | 2004-06-18 | 2005-06-20 | Modulators that promote cell surface expression of odorant receptors |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007516837A Division JP5022217B2 (ja) | 2004-06-18 | 2005-06-20 | 匂い物質受容体のモジュレーター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012105660A JP2012105660A (ja) | 2012-06-07 |
| JP2012105660A5 true JP2012105660A5 (enrdf_load_stackoverflow) | 2012-12-13 |
| JP5340430B2 JP5340430B2 (ja) | 2013-11-13 |
Family
ID=36034502
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007516837A Expired - Fee Related JP5022217B2 (ja) | 2004-06-18 | 2005-06-20 | 匂い物質受容体のモジュレーター |
| JP2012014665A Expired - Lifetime JP5340430B2 (ja) | 2004-06-18 | 2012-01-26 | 匂い物質受容体のモジュレーター |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007516837A Expired - Fee Related JP5022217B2 (ja) | 2004-06-18 | 2005-06-20 | 匂い物質受容体のモジュレーター |
Country Status (9)
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5312314B2 (ja) * | 2006-03-30 | 2013-10-09 | デューク ユニヴァーシティー | 家族性痙性対麻痺の根底にある新規遺伝子の同定 |
| WO2008137993A1 (en) * | 2007-05-08 | 2008-11-13 | Duke University | Compositions and methods for characterizing and regulating olfactory sensation |
| JP5690467B2 (ja) * | 2008-04-11 | 2015-03-25 | 花王株式会社 | 嗅覚感度抑制剤のスクリーニング法 |
| US9068226B2 (en) | 2009-12-04 | 2015-06-30 | Duke University | Compositions and methods for enhancing odorant receptor activity |
| JP5520173B2 (ja) * | 2010-09-16 | 2014-06-11 | 花王株式会社 | ミューゲ香料素材の探索方法 |
| WO2012056603A1 (ja) | 2010-10-25 | 2012-05-03 | パナソニック株式会社 | キメラ嗅覚受容体を用いてｃＡＭＰを産生する方法 |
| CN103608674B (zh) * | 2011-04-14 | 2015-04-22 | 上海交通大学医学院 | 一种配位金属的气味化合物的探测方法 |
| JP5921226B2 (ja) * | 2012-02-02 | 2016-05-24 | 花王株式会社 | ミューゲ香料素材の探索方法 |
| US20130210775A1 (en) | 2012-02-09 | 2013-08-15 | Kao Corporation | Agent for inhibiting odor of pyrazine derivatives |
| EP2893020B1 (en) * | 2012-09-10 | 2018-02-28 | The Johns Hopkins University | Compositions and methods for increasing the expression and signalling of proteins on cell surfaces |
| BR112015032700B1 (pt) | 2013-06-29 | 2022-12-20 | Firmenich Sa | Métodos de identificação, isolamento e uso de receptores de aroma e odorizante |
| EP2832347B1 (en) | 2013-08-02 | 2018-01-31 | Takasago International Corporation | Method for identifying patchouli odorant materials |
| US10041935B2 (en) | 2013-08-05 | 2018-08-07 | New York University | Identification of olfactory receptors sensitive to different odorants |
| US10908147B2 (en) | 2013-12-16 | 2021-02-02 | Monell Chemical Senses Center | Methods of identifying modulators of olfactory receptors |
| WO2015116771A1 (en) | 2014-01-29 | 2015-08-06 | The Johns Hopkins University | Compositions and methods for increasing the expression and signalling of proteins on cell surfaces |
| ES2802524T3 (es) | 2015-06-10 | 2021-01-20 | Firmenich & Cie | Líneas celulares para el cribado de receptores de aroma y olor |
| JP6830949B2 (ja) | 2015-08-03 | 2021-02-17 | リサーチ ファウンデイション オブ ザ シティー ユニヴァーシティ オブ ニューヨーク | 嗅覚系における嗅覚受容体の出現を増大させるｄｎａ配列 |
| CN109071626A (zh) * | 2016-02-24 | 2018-12-21 | 阿罗姆斯公司 | 用于检测气味、香味和味道的生物传感器 |
| EP3519815A1 (en) * | 2016-09-30 | 2019-08-07 | Mars, Incorporated | Screening methods using olfactory receptors and novel compounds identified using the same |
| WO2018081588A1 (en) | 2016-10-27 | 2018-05-03 | Duke University | Methods for vapor detection and discrimination with mammalian odorant receptors expressed in heterologous cells |
| US11255830B2 (en) | 2016-12-30 | 2022-02-22 | Research Foundation Of The City University Of New York | Biosensor exhibiting sensitivity to trinitrotoluene |
| CA3051163A1 (en) | 2017-01-30 | 2018-08-02 | Chemcom S.A. | Compounds reducing malodour perception and the use thereof |
| JP7062636B2 (ja) * | 2017-03-07 | 2022-05-06 | 高砂香料工業株式会社 | マリンノートを呈する香料素材のスクリーニング方法 |
| US10209239B1 (en) | 2017-08-16 | 2019-02-19 | Aromyx Corporation | Method of making an aromagraph comprising ectopic olfactory receptors |
| EP3814371A4 (en) | 2018-06-26 | 2022-07-20 | Duke University | Synthetic odorant receptors |
| US12269315B2 (en) | 2020-08-20 | 2025-04-08 | Denso International America, Inc. | Systems and methods for measuring and managing odor brought into rental vehicles |
| US11932080B2 (en) | 2020-08-20 | 2024-03-19 | Denso International America, Inc. | Diagnostic and recirculation control systems and methods |
| US11881093B2 (en) | 2020-08-20 | 2024-01-23 | Denso International America, Inc. | Systems and methods for identifying smoking in vehicles |
| US11828210B2 (en) | 2020-08-20 | 2023-11-28 | Denso International America, Inc. | Diagnostic systems and methods of vehicles using olfaction |
| US11813926B2 (en) | 2020-08-20 | 2023-11-14 | Denso International America, Inc. | Binding agent and olfaction sensor |
| US11636870B2 (en) | 2020-08-20 | 2023-04-25 | Denso International America, Inc. | Smoking cessation systems and methods |
| US11760170B2 (en) | 2020-08-20 | 2023-09-19 | Denso International America, Inc. | Olfaction sensor preservation systems and methods |
| US12017506B2 (en) | 2020-08-20 | 2024-06-25 | Denso International America, Inc. | Passenger cabin air control systems and methods |
| US12251991B2 (en) | 2020-08-20 | 2025-03-18 | Denso International America, Inc. | Humidity control for olfaction sensors |
| US11760169B2 (en) | 2020-08-20 | 2023-09-19 | Denso International America, Inc. | Particulate control systems and methods for olfaction sensors |
| US12377711B2 (en) | 2020-08-20 | 2025-08-05 | Denso International America, Inc. | Vehicle feature control systems and methods based on smoking |
| GB202108867D0 (en) | 2021-06-21 | 2021-08-04 | Givaudan Sa | Screening system |
| CN120603844A (zh) | 2022-12-15 | 2025-09-05 | 奇华顿股份有限公司 | 经修饰的嗅觉受体 |
| JP2024132485A (ja) * | 2023-03-17 | 2024-10-01 | 住友化学株式会社 | ヒトリガ科の昆虫由来細胞 |
| CN116200456B (zh) * | 2023-04-27 | 2023-07-28 | 汉王科技股份有限公司 | 利用嗅觉受体检测食品变质的方法 |
| CN118501118B (zh) * | 2024-07-16 | 2024-10-29 | 汉王科技股份有限公司 | 一种基于细胞的生物荧光能量共振转移检测系统及应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4861719A (en) | 1986-04-25 | 1989-08-29 | Fred Hutchinson Cancer Research Center | DNA constructs for retrovirus packaging cell lines |
| CA1315719C (en) | 1988-02-05 | 1993-04-06 | Arthur Bank | Retroviral packaging cell lines and processes of using same |
| JP3082204B2 (ja) | 1988-09-01 | 2000-08-28 | ホワイトヘッド・インスティチュート・フォー・バイオメディカル・リサーチ | 両栄養性および環境栄養性宿主域を持つ組換え体レトロウイルス |
| GB8901778D0 (en) | 1989-01-27 | 1989-03-15 | Univ Court Of The University O | Manipulatory technique |
| DE69435108D1 (de) | 1993-07-13 | 2008-08-14 | Centelion | Defekte adenovirus-vektoren und deren verwendung in der gentherapie |
| FR2715847B1 (fr) | 1994-02-08 | 1996-04-12 | Rhone Poulenc Rorer Sa | Composition contenant des acides nucléiques, préparation et utilisations. |
| FR2730637B1 (fr) | 1995-02-17 | 1997-03-28 | Rhone Poulenc Rorer Sa | Composition pharmaceutique contenant des acides nucleiques, et ses utilisations |
| US5993778A (en) * | 1997-05-07 | 1999-11-30 | Firestein; Stuart J. | Functional expression of, and assay for, functional cellular receptors in vivo |
| WO2001051609A1 (en) * | 2000-01-14 | 2001-07-19 | The Johns Hopkins University | Isolation and in vitro differentiation of conditionally immortalized murine olfactory receptor neurons |
| US6436703B1 (en) * | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
| AU2002326910A1 (en) * | 2001-09-14 | 2003-04-01 | Incyte Genomics, Inc. | Receptors and membrane-associated proteins |
| EP1499897A1 (en) * | 2002-05-02 | 2005-01-26 | EVOTEC Neurosciences GmbH | Diagnostic and therapeutic use of ensadin-0255 gene and protein for neurodegenerative diseases |
| PL375202A1 (en) * | 2002-05-07 | 2005-11-28 | Immunex Corporation | Cytokine polypeptides |
| WO2004080148A2 (en) * | 2002-10-02 | 2004-09-23 | Nuvelo, Inc. | Novel nucleic acids and polypeptides |
-
2005
- 2005-06-20 CN CN2005800275380A patent/CN101087879B/zh not_active Expired - Lifetime
- 2005-06-20 WO PCT/US2005/021921 patent/WO2006002161A2/en active Application Filing
- 2005-06-20 US US11/156,516 patent/US7425445B2/en not_active Expired - Lifetime
- 2005-06-20 CA CA2571080A patent/CA2571080C/en not_active Expired - Lifetime
- 2005-06-20 DK DK08013482.8T patent/DK2031063T3/da active
- 2005-06-20 AU AU2005258061A patent/AU2005258061C1/en not_active Expired
- 2005-06-20 EP EP05792749A patent/EP1771582A4/en not_active Withdrawn
- 2005-06-20 JP JP2007516837A patent/JP5022217B2/ja not_active Expired - Fee Related
- 2005-06-20 PL PL08013482T patent/PL2031063T3/pl unknown
- 2005-06-20 EP EP08013482.8A patent/EP2031063B1/en not_active Expired - Lifetime
-
2007
- 2007-06-08 US US11/811,050 patent/US7691592B2/en active Active
-
2008
- 2008-09-09 US US12/207,102 patent/US7879565B2/en not_active Expired - Lifetime
- 2008-10-30 US US12/261,774 patent/US7838288B2/en not_active Expired - Lifetime
- 2008-10-30 US US12/261,778 patent/US20090124003A1/en not_active Abandoned
-
2009
- 2009-10-16 AU AU2009227827A patent/AU2009227827A1/en not_active Ceased
-
2010
- 2010-04-26 US US12/767,294 patent/US20100222561A1/en not_active Abandoned
-
2012
- 2012-01-26 JP JP2012014665A patent/JP5340430B2/ja not_active Expired - Lifetime
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