JP2012025749A5 - - Google Patents
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- Publication number
- JP2012025749A5 JP2012025749A5 JP2011160394A JP2011160394A JP2012025749A5 JP 2012025749 A5 JP2012025749 A5 JP 2012025749A5 JP 2011160394 A JP2011160394 A JP 2011160394A JP 2011160394 A JP2011160394 A JP 2011160394A JP 2012025749 A5 JP2012025749 A5 JP 2012025749A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- composition
- isoform
- unsubstituted
- fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000203 mixture Substances 0.000 claims 11
- 150000001875 compounds Chemical class 0.000 claims 9
- 108090001005 Interleukin-6 Proteins 0.000 claims 7
- 102000001708 Protein Isoforms Human genes 0.000 claims 6
- 108010029485 Protein Isoforms Proteins 0.000 claims 6
- -1 alkyltrimethylammonium halides Chemical class 0.000 claims 6
- 239000012634 fragment Substances 0.000 claims 6
- 150000003839 salts Chemical class 0.000 claims 5
- 229920006395 saturated elastomer Polymers 0.000 claims 5
- 210000002966 serum Anatomy 0.000 claims 4
- 238000000034 method Methods 0.000 claims 3
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 230000000087 stabilizing effect Effects 0.000 claims 2
- CXRFDZFCGOPDTD-UHFFFAOYSA-M Cetrimide Chemical compound [Br-].CCCCCCCCCCCCCC[N+](C)(C)C CXRFDZFCGOPDTD-UHFFFAOYSA-M 0.000 claims 1
- LZZYPRNAOMGNLH-UHFFFAOYSA-M Cetrimonium bromide Chemical compound [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C LZZYPRNAOMGNLH-UHFFFAOYSA-M 0.000 claims 1
- XJWSAJYUBXQQDR-UHFFFAOYSA-M dodecyltrimethylammonium bromide Chemical compound [Br-].CCCCCCCCCCCC[N+](C)(C)C XJWSAJYUBXQQDR-UHFFFAOYSA-M 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10007718A EP2415461B1 (en) | 2010-07-24 | 2010-07-24 | Stabilization of interleukin 6 in serum based solutions |
| EP10007718.9 | 2010-07-24 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012025749A JP2012025749A (ja) | 2012-02-09 |
| JP2012025749A5 true JP2012025749A5 (https=) | 2013-09-05 |
| JP5751965B2 JP5751965B2 (ja) | 2015-07-22 |
Family
ID=43063518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011160394A Active JP5751965B2 (ja) | 2010-07-24 | 2011-07-22 | 血清に基づく溶液中のインターロイキン６の安定化 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US8377882B2 (https=) |
| EP (1) | EP2415461B1 (https=) |
| JP (1) | JP5751965B2 (https=) |
| ES (1) | ES2398646T3 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3605097B1 (en) * | 2017-03-27 | 2024-11-13 | NH Foods Ltd. | Substance that prevents antigen-antibody reaction inhibition by body fluid |
| JP7110360B2 (ja) | 2017-10-09 | 2022-08-01 | テルモ ビーシーティー バイオテクノロジーズ，エルエルシー | 凍結乾燥方法 |
| CN113614477B (zh) | 2019-03-14 | 2023-04-28 | 泰尔茂比司特生物技术有限公司 | 冷冻干燥装载托盘组件及系统 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5078997A (en) * | 1988-07-13 | 1992-01-07 | Cetus Corporation | Pharmaceutical composition for interleukin-2 containing physiologically compatible stabilizers |
| DE3939706C1 (https=) | 1989-12-01 | 1991-03-21 | Centre Regional De Transfusion Sanguine, Besancon, Fr | |
| DE4022878A1 (de) | 1990-07-18 | 1992-01-23 | Boehringer Mannheim Gmbh | Konservierung von diagnostischen tests |
| DE19746868A1 (de) * | 1997-10-23 | 1999-04-29 | Knoll Ag | Verwendung von TNF-Antagonisten als Arzneimittel zur Behandlung von septischen Erkrankungen |
| US20050089918A1 (en) * | 1998-02-23 | 2005-04-28 | Amersham Biosciences Uk Limited | In-situ cell extraction and assay method |
| KR100771294B1 (ko) * | 1999-12-14 | 2007-10-29 | 써모 바이오스타, 인크. | 폴리펩티드 및 항원 안정화 희석제 |
| EP2236618A3 (en) * | 2001-01-31 | 2011-06-08 | Asahi Kasei Pharma Corporation | Compositions for assaying glycoprotein |
| JP4453999B2 (ja) * | 2001-02-14 | 2010-04-21 | 栄研化学株式会社 | 尿中蛋白及びペプチドの安定化方法 |
| US7601491B2 (en) | 2003-02-06 | 2009-10-13 | Becton, Dickinson And Company | Pretreatment method for extraction of nucleic acid from biological samples and kits therefor |
| MXPA05001815A (es) | 2004-02-20 | 2005-08-24 | Hoffmann La Roche | Adsorcion de acidos nucleicos a una fase solida. |
| US20050272101A1 (en) * | 2004-06-07 | 2005-12-08 | Prasad Devarajan | Method for the early detection of renal injury |
| DE602006005806D1 (de) | 2006-07-28 | 2009-04-30 | Vista Ventures Gmbh | Verfahren zum Nachweis der amyloid-beta Oligomere in Körperflüssigkeiten |
| WO2009048962A1 (en) | 2007-10-12 | 2009-04-16 | Vladislav Dolnik | Capillary sieving electrophoresis with a cationic surfactant for size separation of proteins |
| CN102089319B (zh) * | 2008-05-08 | 2013-11-13 | 味之素株式会社 | 蛋白质的重折叠方法 |
-
2010
- 2010-07-24 ES ES10007718T patent/ES2398646T3/es active Active
- 2010-07-24 EP EP10007718A patent/EP2415461B1/en active Active
-
2011
- 2011-06-16 US US13/161,793 patent/US8377882B2/en active Active
- 2011-07-22 JP JP2011160394A patent/JP5751965B2/ja active Active
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