JP2011528556A5 - - Google Patents

Info

Publication number

JP2011528556A5

JP2011528556A5 JP2011518957A JP2011518957A JP2011528556A5 JP 2011528556 A5 JP2011528556 A5 JP 2011528556A5 JP 2011518957 A JP2011518957 A JP 2011518957A JP 2011518957 A JP2011518957 A JP 2011518957A JP 2011528556 A5 JP2011528556 A5 JP 2011528556A5

Authority

JP

Japan

Prior art keywords

animal

composition

weight

composition comprises

omega

Prior art date

2009-07-20

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
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• 238000000034 method Methods 0.000 claims 45
• 239000000203 mixture Substances 0.000 claims 44
• 241001465754 Metazoa Species 0.000 claims 35
• 230000014509 gene expression Effects 0.000 claims 14
• 108090000623 proteins and genes Proteins 0.000 claims 12
• 230000032683 aging Effects 0.000 claims 11
• MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 claims 11
• 235000020660 omega-3 fatty acid Nutrition 0.000 claims 11
• 235000020669 docosahexaenoic acid Nutrition 0.000 claims 9
• 235000020673 eicosapentaenoic acid Nutrition 0.000 claims 9
• 241000282472 Canis lupus familiaris Species 0.000 claims 8
• 239000003925 fat Substances 0.000 claims 7
• 235000019197 fats Nutrition 0.000 claims 7
• 230000008827 biological function Effects 0.000 claims 6
• 235000015097 nutrients Nutrition 0.000 claims 6
• 235000018102 proteins Nutrition 0.000 claims 6
• 102000004169 proteins and genes Human genes 0.000 claims 6
• 241000124008 Mammalia Species 0.000 claims 5
• 230000006872 improvement Effects 0.000 claims 5
• PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 claims 4
• GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims 4
• CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 4
• 230000005778 DNA damage Effects 0.000 claims 4
• 231100000277 DNA damage Toxicity 0.000 claims 4
• 229920002527 Glycogen Polymers 0.000 claims 4
• 230000002776 aggregation Effects 0.000 claims 4
• 238000004220 aggregation Methods 0.000 claims 4
• 239000003963 antioxidant agent Substances 0.000 claims 4
• 235000006708 antioxidants Nutrition 0.000 claims 4
• 230000008236 biological pathway Effects 0.000 claims 4
• 230000015572 biosynthetic process Effects 0.000 claims 4
• 210000000988 bone and bone Anatomy 0.000 claims 4
• 210000000845 cartilage Anatomy 0.000 claims 4
• 230000015556 catabolic process Effects 0.000 claims 4
• 230000008859 change Effects 0.000 claims 4
• HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims 4
• 229960001231 choline Drugs 0.000 claims 4
• OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 claims 4
• 230000007850 degeneration Effects 0.000 claims 4
• 238000006731 degradation reaction Methods 0.000 claims 4
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
• 230000006870 function Effects 0.000 claims 4
• 230000004110 gluconeogenesis Effects 0.000 claims 4
• 229940096919 glycogen Drugs 0.000 claims 4
• 230000034659 glycolysis Effects 0.000 claims 4
• 230000028709 inflammatory response Effects 0.000 claims 4
• 210000003205 muscle Anatomy 0.000 claims 4
• 210000005036 nerve Anatomy 0.000 claims 4
• 230000037361 pathway Effects 0.000 claims 4
• 230000004108 pentose phosphate pathway Effects 0.000 claims 4
• 230000010118 platelet activation Effects 0.000 claims 4
• 230000008439 repair process Effects 0.000 claims 4
• 230000004044 response Effects 0.000 claims 4
• 238000003786 synthesis reaction Methods 0.000 claims 4
• XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims 4
• LEVWYRKDKASIDU-QWWZWVQMSA-N D-cystine Chemical compound OC(=O)[C@H](N)CSSC[C@@H](N)C(O)=O LEVWYRKDKASIDU-QWWZWVQMSA-N 0.000 claims 3
• 241000282326 Felis catus Species 0.000 claims 3
• KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 claims 3
• FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims 3
• 239000004472 Lysine Substances 0.000 claims 3
• KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 3
• 108010064851 Plant Proteins Proteins 0.000 claims 3
• 235000021120 animal protein Nutrition 0.000 claims 3
• 230000003078 antioxidant effect Effects 0.000 claims 3
• 230000009286 beneficial effect Effects 0.000 claims 3
• 230000023555 blood coagulation Effects 0.000 claims 3
• 150000001720 carbohydrates Chemical class 0.000 claims 3
• 235000014633 carbohydrates Nutrition 0.000 claims 3
• 229960003067 cystine Drugs 0.000 claims 3
• 239000000835 fiber Substances 0.000 claims 3
• 229910052500 inorganic mineral Inorganic materials 0.000 claims 3
• WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 claims 3
• 229930182817 methionine Natural products 0.000 claims 3
• 239000011707 mineral Substances 0.000 claims 3
• 235000021118 plant-derived protein Nutrition 0.000 claims 3
• 230000027756 respiratory electron transport chain Effects 0.000 claims 3
• 235000019871 vegetable fat Nutrition 0.000 claims 3
• 229930003231 vitamin Natural products 0.000 claims 3
• 235000013343 vitamin Nutrition 0.000 claims 3
• 239000011782 vitamin Substances 0.000 claims 3
• 229940088594 vitamin Drugs 0.000 claims 3
• ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims 2
• 230000033616 DNA repair Effects 0.000 claims 2
• 241000282412 Homo Species 0.000 claims 2
• 206010061218 Inflammation Diseases 0.000 claims 2
• 229930003268 Vitamin C Natural products 0.000 claims 2
• 229930003427 Vitamin E Natural products 0.000 claims 2
• JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 claims 2
• 230000030833 cell death Effects 0.000 claims 2
• 230000004663 cell proliferation Effects 0.000 claims 2
• 201000010099 disease Diseases 0.000 claims 2
• 208000035475 disorder Diseases 0.000 claims 2
• 229940090949 docosahexaenoic acid Drugs 0.000 claims 2
• JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 claims 2
• 229960005135 eicosapentaenoic acid Drugs 0.000 claims 2
• WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims 2
• 230000004054 inflammatory process Effects 0.000 claims 2
• 230000004060 metabolic process Effects 0.000 claims 2
• 238000001243 protein synthesis Methods 0.000 claims 2
• 230000004083 survival effect Effects 0.000 claims 2
• 229960003080 taurine Drugs 0.000 claims 2
• 230000014616 translation Effects 0.000 claims 2
• 235000019154 vitamin C Nutrition 0.000 claims 2
• 239000011718 vitamin C Substances 0.000 claims 2
• 235000019165 vitamin E Nutrition 0.000 claims 2
• 229940046009 vitamin E Drugs 0.000 claims 2
• 239000011709 vitamin E Substances 0.000 claims 2
• XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 claims 1
• OENHQHLEOONYIE-UKMVMLAPSA-N all-trans beta-carotene Natural products CC=1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C OENHQHLEOONYIE-UKMVMLAPSA-N 0.000 claims 1
• 235000013734 beta-carotene Nutrition 0.000 claims 1
• TUPZEYHYWIEDIH-WAIFQNFQSA-N beta-carotene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2=CCCCC2(C)C TUPZEYHYWIEDIH-WAIFQNFQSA-N 0.000 claims 1
• 239000011648 beta-carotene Substances 0.000 claims 1
• 229960002747 betacarotene Drugs 0.000 claims 1
• 229960004203 carnitine Drugs 0.000 claims 1
• 230000015271 coagulation Effects 0.000 claims 1
• 238000005345 coagulation Methods 0.000 claims 1
• XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims 1
• 235000018417 cysteine Nutrition 0.000 claims 1
• 235000015872 dietary supplement Nutrition 0.000 claims 1
• AGBQKNBQESQNJD-UHFFFAOYSA-M lipoate Chemical compound [O-]C(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-M 0.000 claims 1
• 235000019136 lipoic acid Nutrition 0.000 claims 1
• 238000005259 measurement Methods 0.000 claims 1
• 230000008569 process Effects 0.000 claims 1
• 108090000765 processed proteins & peptides Proteins 0.000 claims 1
• 230000001105 regulatory effect Effects 0.000 claims 1
• 230000009758 senescence Effects 0.000 claims 1
• 235000011888 snacks Nutrition 0.000 claims 1
• 229960002663 thioctic acid Drugs 0.000 claims 1
• OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 claims 1