JP2011528332A - 哺乳動物ベータ・デフェンシンを用いた炎症性疾患の処置 - Google Patents

哺乳動物ベータ・デフェンシンを用いた炎症性疾患の処置 Download PDF

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JP2011528332A
JP2011528332A JP2011517954A JP2011517954A JP2011528332A JP 2011528332 A JP2011528332 A JP 2011528332A JP 2011517954 A JP2011517954 A JP 2011517954A JP 2011517954 A JP2011517954 A JP 2011517954A JP 2011528332 A JP2011528332 A JP 2011528332A
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defensin
tnf
beta defensin
hbd2
human
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JP2011528332A5 (https=
Inventor
マリア ローゼンキルデ キエール,タンヤ
クルーセ,トマス
ホルセ ミギンド,ペル
シデルマン ブリンチ,カロリーネ
クイェルルフ,セレン
アンデルセン,ビルギッテ
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ノボザイムス アデニウム バイオテック アクティーゼルスカブ
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1729Cationic antimicrobial peptides, e.g. defensins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Plant Substances (AREA)
JP2011517954A 2008-07-18 2009-07-17 哺乳動物ベータ・デフェンシンを用いた炎症性疾患の処置 Pending JP2011528332A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
EP08160761.6 2008-07-18
EP08160761 2008-07-18
EP08162486.8 2008-08-15
EP08162486 2008-08-15
EP08163614 2008-09-03
EP08163614.4 2008-09-03
EP09160448.8 2009-05-15
EP09160448 2009-05-15
PCT/EP2009/059251 WO2010007165A2 (en) 2008-07-18 2009-07-17 Treatment of inflammatory diseases with mammal beta defensins

Publications (2)

Publication Number Publication Date
JP2011528332A true JP2011528332A (ja) 2011-11-17
JP2011528332A5 JP2011528332A5 (https=) 2012-04-12

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JP2011517954A Pending JP2011528332A (ja) 2008-07-18 2009-07-17 哺乳動物ベータ・デフェンシンを用いた炎症性疾患の処置

Country Status (18)

Country Link
US (1) US20100016232A1 (https=)
EP (1) EP2320929B1 (https=)
JP (1) JP2011528332A (https=)
KR (2) KR20110031962A (https=)
CN (1) CN102159232A (https=)
AP (1) AP2011005537A0 (https=)
AR (1) AR072524A1 (https=)
AU (1) AU2009272680A1 (https=)
BR (1) BRPI0915780A2 (https=)
CA (1) CA2730674A1 (https=)
CL (1) CL2011000098A1 (https=)
EA (1) EA201170218A1 (https=)
IL (1) IL210714A0 (https=)
MX (1) MX2011000569A (https=)
NZ (1) NZ590466A (https=)
TW (1) TW201004641A (https=)
WO (1) WO2010007165A2 (https=)
ZA (1) ZA201100462B (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011528334A (ja) * 2008-07-18 2011-11-17 ノボザイムス アデニウム バイオテック アクティーゼルスカブ 哺乳動物のベータ・ディフェンシンを用いた、関節リウマチの治療
JP2015000048A (ja) * 2013-06-18 2015-01-05 国立大学法人京都大学 関節リウマチ患者における生物学的製剤の有効性の予測方法
JP2020512287A (ja) * 2016-12-13 2020-04-23 ディフェンシン セラピューティクス エーピーエス 肺の炎症性疾患を処置するための方法

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG172709A1 (en) 2008-07-18 2011-07-28 Novozymes Adenium Biotech As Treatment of inflammatory bowel diseases with mammal beta defensins
BR112012025844A2 (pt) 2010-04-15 2017-07-18 Marine Polymer Tech Inc uso de nanofibras snag
KR101329774B1 (ko) * 2010-06-16 2013-11-15 주식회사 나이벡 항균 또는 항염증 활성을 가지는 펩타이드 및 이를 유효성분으로 함유하는 약제학적 조성물
CA2832859C (en) * 2011-04-15 2020-06-16 Marine Polymer Technologies, Inc. Treatment of disease with poly-n-acetylglucosamine nanofibers
JP6219277B2 (ja) 2011-07-08 2017-10-25 ディフェンシン セラピューティクス アンパルトセルスカブDefensin Therapeutics Aps 炎症性腸疾患の経口治療
US20130052213A1 (en) 2011-08-19 2013-02-28 Novozymes A/S Novel immunomodulatory peptide
JP2017525370A (ja) 2014-08-21 2017-09-07 ザ ジェネラル ホスピタル コーポレイション 腫瘍壊死因子スーパーファミリーおよびtnf様リガンドムテインならびに腫瘍壊死因子スーパーファミリーおよびtnf様リガンドムテインを調製および使用する方法
GB201603653D0 (en) * 2016-03-02 2016-04-13 Cambridge Entpr Ltd Combination Therapy
CN109414474B (zh) 2016-04-29 2024-07-02 诺维信公司 肝脏、胆道和胰腺障碍的治疗
KR102631542B1 (ko) * 2018-03-14 2024-02-01 서울대학교산학협력단 염증 감소능 및 줄기세포로부터 연골세포로의 분화 촉진능을 가지는 이중 기능성 펩타이드 및 이의 용도
KR102631543B1 (ko) 2018-03-14 2024-02-01 서울대학교산학협력단 세포 투과능 및 근육 재생능을 가지는 이중 기능성 펩타이드 및 이의 용도
WO2020046002A1 (ko) * 2018-08-31 2020-03-05 주식회사 나이벡 다중의 질환 바이오마커의 기능 및 발현을 억제하는 펩타이드의 신규한 용도
KR102244161B1 (ko) 2018-08-31 2021-04-26 주식회사 나이벡 다중의 질환 바이오마커의 기능 및 발현을 억제하는 펩타이드의 신규한 용도
CA3249846A1 (en) 2022-01-28 2023-08-03 Kenvue Brands Llc Predictive Biomarkers for Atopic Dermatitis
KR20250025597A (ko) 2022-04-04 2025-02-24 존슨 앤드 존슨 컨수머 인코포레이티드 아토피성 피부염의 발병을 예방하거나 아토피성 피부염을 치료하기 위한 기회의 창 피부 치료 요법 및 조성물

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WO2007007116A1 (en) * 2005-07-14 2007-01-18 Ares Trading S.A Defensin proteins
JP2011528334A (ja) * 2008-07-18 2011-11-17 ノボザイムス アデニウム バイオテック アクティーゼルスカブ 哺乳動物のベータ・ディフェンシンを用いた、関節リウマチの治療

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WO2007081486A2 (en) * 2005-12-15 2007-07-19 Ventria Bioscience Oral administration of defensins to treat intestinal diseases
KR20100071985A (ko) * 2007-09-11 2010-06-29 몬도바이오테크 래보래토리즈 아게 치료제로서의 데펜신 펩티드의 용도
SG172709A1 (en) * 2008-07-18 2011-07-28 Novozymes Adenium Biotech As Treatment of inflammatory bowel diseases with mammal beta defensins

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Publication number Priority date Publication date Assignee Title
WO2007007116A1 (en) * 2005-07-14 2007-01-18 Ares Trading S.A Defensin proteins
JP2011528334A (ja) * 2008-07-18 2011-11-17 ノボザイムス アデニウム バイオテック アクティーゼルスカブ 哺乳動物のベータ・ディフェンシンを用いた、関節リウマチの治療

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011528334A (ja) * 2008-07-18 2011-11-17 ノボザイムス アデニウム バイオテック アクティーゼルスカブ 哺乳動物のベータ・ディフェンシンを用いた、関節リウマチの治療
JP2015000048A (ja) * 2013-06-18 2015-01-05 国立大学法人京都大学 関節リウマチ患者における生物学的製剤の有効性の予測方法
JP2020512287A (ja) * 2016-12-13 2020-04-23 ディフェンシン セラピューティクス エーピーエス 肺の炎症性疾患を処置するための方法
US11413328B2 (en) 2016-12-13 2022-08-16 Novozymes A/S Methods for treating inflammatory conditions of the lungs

Also Published As

Publication number Publication date
IL210714A0 (en) 2011-03-31
WO2010007165A3 (en) 2010-06-03
NZ590466A (en) 2012-08-31
KR20110031962A (ko) 2011-03-29
AP2011005537A0 (en) 2011-02-28
CA2730674A1 (en) 2010-01-21
KR20110044863A (ko) 2011-05-02
EP2320929B1 (en) 2019-05-29
WO2010007165A2 (en) 2010-01-21
US20100016232A1 (en) 2010-01-21
ZA201100462B (en) 2013-03-27
MX2011000569A (es) 2011-02-23
EA201170218A1 (ru) 2011-08-30
AR072524A1 (es) 2010-09-01
CN102159232A (zh) 2011-08-17
AU2009272680A1 (en) 2010-01-21
CL2011000098A1 (es) 2011-10-07
EP2320929A2 (en) 2011-05-18
TW201004641A (en) 2010-02-01
BRPI0915780A2 (pt) 2019-03-12

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