JP2011525354A5 - - Google Patents

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Publication number
JP2011525354A5
JP2011525354A5 JP2011514065A JP2011514065A JP2011525354A5 JP 2011525354 A5 JP2011525354 A5 JP 2011525354A5 JP 2011514065 A JP2011514065 A JP 2011514065A JP 2011514065 A JP2011514065 A JP 2011514065A JP 2011525354 A5 JP2011525354 A5 JP 2011525354A5
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gln
thr
ala
arg
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JP2011514065A
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JP5711118B2 (ja
JP2011525354A (ja
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Priority claimed from PCT/EP2009/057925 external-priority patent/WO2009156456A1/en
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JP2011514065A 2008-06-24 2009-06-24 所与の標的に対してアフィニティーを有するhNGALおよび類縁タンパク質のムテイン Active JP5711118B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7517508P 2008-06-24 2008-06-24
US61/075,175 2008-06-24
PCT/EP2009/057925 WO2009156456A1 (en) 2008-06-24 2009-06-24 Muteins of hngal and related proteins with affinity for a given target

Publications (3)

Publication Number Publication Date
JP2011525354A JP2011525354A (ja) 2011-09-22
JP2011525354A5 true JP2011525354A5 (enExample) 2014-12-04
JP5711118B2 JP5711118B2 (ja) 2015-04-30

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ID=41256028

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JP2011514065A Active JP5711118B2 (ja) 2008-06-24 2009-06-24 所与の標的に対してアフィニティーを有するhNGALおよび類縁タンパク質のムテイン

Country Status (7)

Country Link
US (2) US8420051B2 (enExample)
EP (2) EP3381933B1 (enExample)
JP (1) JP5711118B2 (enExample)
AU (1) AU2009264214B2 (enExample)
CA (1) CA2729322C (enExample)
DK (1) DK3381933T3 (enExample)
WO (1) WO2009156456A1 (enExample)

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CA2724384A1 (en) 2008-05-15 2009-11-19 Transmolecular, Inc. Treatment of metastatic tumors
EP3381933B1 (en) * 2008-06-24 2020-06-03 Technische Universität München Muteins of hngal and related proteins with affinity for a given target
EP2510357B1 (en) * 2009-12-07 2016-03-30 Pieris AG Muteins of human lipocalin 2 (lcn2, hngal) with affinity for a given target
HRP20171291T1 (hr) 2010-02-04 2017-10-20 Morphotek, Inc. Polipeptidi i konjugati klorotoksina i njihove uporabe
CN103097403B (zh) 2010-05-11 2017-04-19 弗雷德哈钦森癌症研究中心 氯毒素变体、缀合物及其使用方法
WO2011149962A1 (en) 2010-05-24 2011-12-01 The Trustees Of Columbia University In The City Of New York Mutant ngal proteins and uses thereof
CN103154023B (zh) * 2010-08-16 2017-04-05 皮里斯制药有限公司 铁调素的结合蛋白
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US9758554B2 (en) 2012-01-31 2017-09-12 Technische Universitaet Muenchen Muteins of α1m lipocalin and method of production therefor
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US10526384B2 (en) 2012-11-19 2020-01-07 Pieris Pharmaceuticals Gmbh Interleukin-17A-specific and interleukin-23-specific binding polypeptides and uses thereof
EP2925337B1 (en) * 2012-11-21 2019-07-03 The Trustees of Columbia University in the City of New York Mutant ngal proteins and uses thereof
CA2913127A1 (en) * 2012-12-10 2014-06-19 Fred Hutchinson Cancer Research Center Methods for screening
US11559580B1 (en) 2013-09-17 2023-01-24 Blaze Bioscience, Inc. Tissue-homing peptide conjugates and methods of use thereof
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RU2720688C2 (ru) * 2015-01-28 2020-05-12 ПИЕРИС ФАРМАСЬЮТИКАЛС ГмбХ Новые белки, специфические в отношении ангиогенеза
AU2016221816B2 (en) 2015-02-18 2020-07-02 Pieris Pharmaceuticals Gmbh Novel proteins specific for pyoverdine and pyochelin
AU2016258952C1 (en) 2015-05-04 2020-12-24 Pieris Pharmaceuticals Gmbh Proteins specific for CD137
AU2016258977C1 (en) * 2015-05-04 2022-07-14 Pieris Pharmaceuticals Gmbh Anti-cancer fusion polypeptide
RU2754466C2 (ru) 2015-05-18 2021-09-02 ПИЕРИС ФАРМАСЬЮТИКАЛС ГмбХ Слитый полипептид с противораковой активностью
US10273275B2 (en) 2015-05-18 2019-04-30 Pieris Pharmaceuticals Gmbh Muteins of human lipocalin 2 with affinity for glypican-3 (GPC3) and methods of use thereof
EP3115371A1 (en) 2015-07-07 2017-01-11 Sanofi Fusion molecules
EP3115066A1 (en) 2015-07-07 2017-01-11 Technische Universität München Novel psma-specific binding proteins
CN108699162A (zh) 2015-11-30 2018-10-23 皮里斯澳大利亚有限公司 新型抗血管生成融合多肽
TW201725212A (zh) 2015-12-10 2017-07-16 第一三共股份有限公司 特異性於降鈣素基因相關胜肽的新穎蛋白
CA3021011A1 (en) 2016-04-15 2017-10-19 Blaze Bioscience, Inc. Methods of treating breast cancer
AU2017260274A1 (en) * 2016-05-04 2018-11-01 Navigo Proteins Gmbh Targeted compounds for the site-specific coupling of chemical moieties comprising a peptide linker
WO2018044812A2 (en) 2016-08-29 2018-03-08 Fred Hutchinson Cancer Research Center Chelating platform for delivery of radionuclides

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