JP2011522892A - パーキンソン病緩和のためのラサギリン - Google Patents
パーキンソン病緩和のためのラサギリン Download PDFInfo
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- JP2011522892A JP2011522892A JP2011513503A JP2011513503A JP2011522892A JP 2011522892 A JP2011522892 A JP 2011522892A JP 2011513503 A JP2011513503 A JP 2011513503A JP 2011513503 A JP2011513503 A JP 2011513503A JP 2011522892 A JP2011522892 A JP 2011522892A
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- Prior art keywords
- rasagiline
- parkinson
- disease
- patient
- pharmaceutically acceptable
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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| JP2014508758A (ja) * | 2011-02-23 | 2014-04-10 | ユニバルシテ ラバル | パーキンソン病を治療するためのシスタミン類似体 |
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| US20060018957A1 (en) * | 2004-07-26 | 2006-01-26 | Lerner E I | Pharmaceutical dosage forms including rasagiline |
| ES2371883T3 (es) * | 2004-11-24 | 2012-01-11 | Teva Pharmaceutical Industries Ltd. | Composiciones de rasagilina de disgregación oral. |
| US8809310B2 (en) * | 2006-02-21 | 2014-08-19 | Teva Pharmaceutical Industries, Ltd. | Use of rasagiline for the treatment of multiple system atrophy |
| AU2007235517B2 (en) | 2006-04-03 | 2013-01-31 | Teva Pharmaceutical Industries, Ltd. | Use of rasagiline for the treatment of Restless Legs Syndrome |
| EP1892233A1 (de) | 2006-08-18 | 2008-02-27 | Ratiopharm GmbH | Neue Salze des Wirkstoffs Rasagilin |
| EP1987816A1 (de) * | 2007-04-30 | 2008-11-05 | Ratiopharm GmbH | Adsorbate eines Rasagilinsalzes mit einem wasserlöslichen Hilfsstoff |
| US20090062400A1 (en) * | 2007-09-05 | 2009-03-05 | Laurence Oron | Method of treating glaucoma using rasagiline |
| US8188149B2 (en) * | 2007-09-17 | 2012-05-29 | Teva Pharmaceutical Industries, Ltd. | Use of R(+)-N-propargy1-1-aminoindan to treat or prevent hearing loss |
| EA201070842A1 (ru) * | 2008-01-11 | 2011-04-29 | Тева Фармасьютикал Индастриз, Лтд. | Препаративные формы разагилина, их получение и применение |
| AU2009258120B2 (en) * | 2008-06-10 | 2014-11-27 | Teva Pharmaceutical Industries, Ltd. | Rasagiline soft gelatin capsules |
| JP2011525489A (ja) * | 2008-06-19 | 2011-09-22 | テバ ファーマシューティカル インダストリーズ リミティド | ラサリジン塩基の精製方法 |
| NZ589547A (en) | 2008-06-19 | 2013-03-28 | Teva Pharma | Dried rasagiline base having a water content less than 0.5 % by weight |
| US20100189790A1 (en) * | 2009-01-23 | 2010-07-29 | Teva Pharmaceutical Industries, Ltd. | Delayed release rasagiline formulation |
| PT2451771E (pt) | 2009-07-09 | 2014-09-19 | Ratiopharm Gmbh | Sais de rasagilina e suas preparações farmacêuticas |
| WO2011087791A1 (en) * | 2009-12-22 | 2011-07-21 | Teva Pharmaceutical Industries Ltd. | 3-keto-n-propargyl-1-aminoindan |
| RU2587330C2 (ru) * | 2010-07-27 | 2016-06-20 | Тева Фармасьютикал Индастриз Лтд. | Применение разагилина для лечения обонятельной дисфункции |
| WO2012015946A1 (en) * | 2010-07-27 | 2012-02-02 | Teva Pharmaceutical Industries Ltd. | Dispersion of rasagiline citrate |
| CN103188933A (zh) * | 2010-10-26 | 2013-07-03 | 泰华制药工业有限公司 | 富集氘的雷沙吉兰 |
| CA2851433A1 (en) | 2011-10-10 | 2013-04-18 | Teva Pharmaceutical Industries Ltd. | R(+)-n-methyl-propargyl-aminoindan |
| BR112014008555A2 (pt) | 2011-10-10 | 2017-04-18 | Teva Pharma | r(+)-n-formil-propargil-aminoindano |
| US20130089611A1 (en) * | 2011-10-10 | 2013-04-11 | Teva Pharmaceutical Industries, Ltd. | Rasagiline citramide |
| AR092168A1 (es) | 2012-08-17 | 2015-03-25 | Teva Pharma | Formulaciones parenterales de rasagilina |
| CA2943841A1 (en) * | 2014-04-01 | 2015-10-08 | Teva Pharmaceutical Industries Ltd. | Determination of single nucleotide polymorphisms useful to predict response for rasagiline |
| EP3432931A1 (en) * | 2016-03-26 | 2019-01-30 | Dr. Reddy's Laboratories Ltd. | Pharmaceutical compositons for n-propargylamine derivative |
| EP3606541A1 (en) * | 2017-04-05 | 2020-02-12 | Crestovo Holdings LLC | Compositions and methods for treating parkinson's disease (pd) and related disorders |
| CA3127590A1 (en) * | 2019-01-28 | 2020-08-06 | Mitochondria Emotion, Inc. | Mitofusin activators and methods of use thereof |
| GB202109826D0 (en) * | 2021-07-07 | 2021-08-18 | Bial Portela & Ca Sa | Treatment regimens for early idiopathic parkinson's disease |
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| US5744500A (en) * | 1990-01-03 | 1998-04-28 | Teva Pharmaceutical Industries, Ltd. | Use of R-enantiomer of N-propargyl-1-aminoindan, salts, and compositions thereof |
| CN1031995C (zh) * | 1991-01-02 | 1996-06-12 | 奥韦特有限公司 | N-炔丙基-1-氨基茚满的r-对映体的制法 |
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| IL115357A (en) * | 1995-09-20 | 2000-01-31 | Teva Pharma | Stable compositions containing N-propargyl-1-aminoindan and polyhydric alcohols |
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| CA2275425C (en) * | 1996-12-18 | 2009-08-04 | Michael Chorev | Aminoindan derivatives |
| AU2002319615A1 (en) * | 2001-07-20 | 2003-03-03 | Mount Sinai School Of Medicine Of New York University | Methods for diagnosing and treating alzheimer's disease and parkinson's disease |
| CA2471760A1 (en) * | 2001-12-28 | 2003-07-17 | Takeda Chemical Industries, Ltd. | Preventives/remedies for urinary disturbance |
| SI1567152T1 (sl) * | 2002-11-15 | 2013-10-30 | Teva Pharmaceutical Industries Ltd. | Uporaba rasagilina z riluzolom za zdravljenje amiotrofične lateralne skleroze |
| US20050031651A1 (en) * | 2002-12-24 | 2005-02-10 | Francine Gervais | Therapeutic formulations for the treatment of beta-amyloid related diseases |
| AR044007A1 (es) * | 2003-04-11 | 2005-08-24 | Newron Pharmaceuticals Inc | Metodos para el tratamiento de la enfermedad de parkinson |
| US20060018957A1 (en) * | 2004-07-26 | 2006-01-26 | Lerner E I | Pharmaceutical dosage forms including rasagiline |
| ES2371883T3 (es) * | 2004-11-24 | 2012-01-11 | Teva Pharmaceutical Industries Ltd. | Composiciones de rasagilina de disgregación oral. |
| US7815942B2 (en) * | 2005-02-23 | 2010-10-19 | Teva Pharmaceutical Industries, Ltd. | Rasagiline formulations of improved content uniformity |
| US7491847B2 (en) * | 2005-11-17 | 2009-02-17 | Teva Pharmaceutical Industries, Ltd. | Methods for isolating propargylated aminoindans |
| US7572834B1 (en) * | 2005-12-06 | 2009-08-11 | Teva Pharmaceutical Industries, Ltd. | Rasagiline formulations and processes for their preparation |
| US8809310B2 (en) * | 2006-02-21 | 2014-08-19 | Teva Pharmaceutical Industries, Ltd. | Use of rasagiline for the treatment of multiple system atrophy |
| US9066903B2 (en) * | 2006-02-28 | 2015-06-30 | The United States Of America As Represented By The Department Of Veterans Affairs | Pharmacological treatment of Parkinson's disease |
| CN101032474B (zh) * | 2006-03-06 | 2011-02-16 | 重庆医药工业研究院有限责任公司 | 一种治疗或预防神经系统疾病的雷沙吉兰透皮贴片及其制备方法 |
| AU2007235517B2 (en) * | 2006-04-03 | 2013-01-31 | Teva Pharmaceutical Industries, Ltd. | Use of rasagiline for the treatment of Restless Legs Syndrome |
| EP1892233A1 (de) * | 2006-08-18 | 2008-02-27 | Ratiopharm GmbH | Neue Salze des Wirkstoffs Rasagilin |
| UA97382C2 (ru) * | 2006-12-14 | 2012-02-10 | Тева Фармасьютікл Індастріз, Лтд. | Таннат разагилина |
| AU2007334428B2 (en) * | 2006-12-14 | 2014-05-29 | Teva Pharmaceutical Industries, Ltd. | Crystalline solid rasagiline base |
| EP1987816A1 (de) * | 2007-04-30 | 2008-11-05 | Ratiopharm GmbH | Adsorbate eines Rasagilinsalzes mit einem wasserlöslichen Hilfsstoff |
| WO2009032202A1 (en) * | 2007-08-29 | 2009-03-12 | Nuon Therapeutics, Inc. | Treatment of brain disorders |
| US20090062400A1 (en) * | 2007-09-05 | 2009-03-05 | Laurence Oron | Method of treating glaucoma using rasagiline |
| US8188149B2 (en) * | 2007-09-17 | 2012-05-29 | Teva Pharmaceutical Industries, Ltd. | Use of R(+)-N-propargy1-1-aminoindan to treat or prevent hearing loss |
| EA201070842A1 (ru) * | 2008-01-11 | 2011-04-29 | Тева Фармасьютикал Индастриз, Лтд. | Препаративные формы разагилина, их получение и применение |
| AU2009258120B2 (en) * | 2008-06-10 | 2014-11-27 | Teva Pharmaceutical Industries, Ltd. | Rasagiline soft gelatin capsules |
| NZ589547A (en) * | 2008-06-19 | 2013-03-28 | Teva Pharma | Dried rasagiline base having a water content less than 0.5 % by weight |
| JP2011525489A (ja) * | 2008-06-19 | 2011-09-22 | テバ ファーマシューティカル インダストリーズ リミティド | ラサリジン塩基の精製方法 |
| DE102008064061A1 (de) * | 2008-12-19 | 2010-06-24 | Ratiopharm Gmbh | Feste Zusammensetzung mit dem Wirkstoff Rasagilin |
| US20100189790A1 (en) * | 2009-01-23 | 2010-07-29 | Teva Pharmaceutical Industries, Ltd. | Delayed release rasagiline formulation |
| JP2013507352A (ja) * | 2009-10-09 | 2013-03-04 | テバ ファーマシューティカル インダストリーズ リミティド | 進行性核上性麻痺の治療のためのラサギリンの使用 |
| WO2011087791A1 (en) * | 2009-12-22 | 2011-07-21 | Teva Pharmaceutical Industries Ltd. | 3-keto-n-propargyl-1-aminoindan |
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- 2009-06-12 NZ NZ589445A patent/NZ589445A/xx unknown
- 2009-06-12 EP EP20130176166 patent/EP2666356A1/en not_active Withdrawn
- 2009-06-12 US US12/456,166 patent/US20090312436A1/en not_active Abandoned
- 2009-06-12 CN CN201310714021.5A patent/CN103893160A/zh active Pending
- 2009-06-12 CN CN2009801230031A patent/CN102065687A/zh active Pending
- 2009-06-12 EA EA201170018A patent/EA201170018A1/ru unknown
- 2009-06-12 CA CA2727022A patent/CA2727022A1/en not_active Abandoned
- 2009-06-12 BR BRPI0909894-1A patent/BRPI0909894A2/pt not_active IP Right Cessation
-
2010
- 2010-11-04 IL IL209131A patent/IL209131A0/en unknown
- 2010-11-25 ZA ZA2010/08484A patent/ZA201008484B/en unknown
-
2013
- 2013-11-27 US US14/092,526 patent/US20140243418A1/en not_active Abandoned
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2014
- 2014-12-17 JP JP2014255148A patent/JP2015096532A/ja active Pending
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2016
- 2016-11-15 AU AU2016259315A patent/AU2016259315A1/en not_active Abandoned
- 2016-12-02 JP JP2016234976A patent/JP2017081938A/ja not_active Withdrawn
Non-Patent Citations (4)
| Title |
|---|
| JPN6013056741; 永井将弘ら: '今後出てくる新しい治療法' Ｐｈａｒｍａ Ｍｅｄｉｃａ Ｖｏｌ．２４、Ｎｏ．９, 2006, ｐ．５７-６０ * |
| JPN6013056744; 長谷川一子: 'パーキンソン病では、薬物治療を早期に始めるほうが、病状進行を遅くすることができるのか？' 治療 Ｖｏｌ．８８、増刊号, 2006, ｐ．１１０７-１１１１ * |
| JPN6013056747; Ｐａｒｋｉｎｓｏｎ Ｓｔｕｄｙ Ｇｒｏｕｐ: 'Ａ Ｃｏｎｔｒｏｌｌｅｄ， Ｒａｎｄｏｍｉｚｅｄ， Ｄｅｌａｙｅｄ-Ｓｔａｒｔ Ｓｔｕｄｙ ｏｆ Ｒａｓａｇｉｌｉｎｅ ｉｎ Ｅａｒｌｙ Ｐａｒｋｉｎｓｏｎ Ｄｉｓｅａｓｅ' Ａｒｃｈ Ｎｅｕｒｏｌ Ｖｏｌ．６１, 2004, ｐ．５６１-５６６ * |
| JPN6013056751; Ｖ．Ｏｌｄｆｉｅｌｄ ｅｔ．ａｌ．: 'Ｒａｓａｇｉｌｉｎｅ' Ｄｒｕｇｓ Ｖｏｌ．６７, 2007, ｐ．１７２５-１７４７ * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014508758A (ja) * | 2011-02-23 | 2014-04-10 | ユニバルシテ ラバル | パーキンソン病を治療するためのシスタミン類似体 |
Also Published As
| Publication number | Publication date |
|---|---|
| MX2010013766A (es) | 2011-03-15 |
| JP2017081938A (ja) | 2017-05-18 |
| NZ589445A (en) | 2013-06-28 |
| EA201170018A1 (ru) | 2011-08-30 |
| AU2016259315A1 (en) | 2016-12-01 |
| CN103893160A (zh) | 2014-07-02 |
| AU2009258151A1 (en) | 2009-12-17 |
| CN102065687A (zh) | 2011-05-18 |
| EP2296462A4 (en) | 2011-06-15 |
| ZA201008484B (en) | 2012-05-30 |
| WO2009151625A1 (en) | 2009-12-17 |
| JP2015096532A (ja) | 2015-05-21 |
| BRPI0909894A2 (pt) | 2015-07-28 |
| EP2666356A1 (en) | 2013-11-27 |
| CA2727022A1 (en) | 2009-12-17 |
| IL209131A0 (en) | 2011-01-31 |
| EP2296462A1 (en) | 2011-03-23 |
| US20140243418A1 (en) | 2014-08-28 |
| US20090312436A1 (en) | 2009-12-17 |
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