JP2011520977A5 - - Google Patents
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- Publication number
- JP2011520977A5 JP2011520977A5 JP2011510691A JP2011510691A JP2011520977A5 JP 2011520977 A5 JP2011520977 A5 JP 2011520977A5 JP 2011510691 A JP2011510691 A JP 2011510691A JP 2011510691 A JP2011510691 A JP 2011510691A JP 2011520977 A5 JP2011520977 A5 JP 2011520977A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- pharmaceutically acceptable
- solvate
- compound
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5477408P | 2008-05-20 | 2008-05-20 | |
| US61/054,774 | 2008-05-20 | ||
| PCT/US2009/044743 WO2009143295A1 (en) | 2008-05-20 | 2009-05-20 | Water-soluble acetaminophen analogs |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014049672A Division JP2014111658A (ja) | 2008-05-20 | 2014-03-13 | 水溶性アセトアミノフェン類似体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011520977A JP2011520977A (ja) | 2011-07-21 |
| JP2011520977A5 true JP2011520977A5 (https=) | 2012-07-05 |
| JP5757864B2 JP5757864B2 (ja) | 2015-08-05 |
Family
ID=41340538
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011510691A Expired - Fee Related JP5757864B2 (ja) | 2008-05-20 | 2009-05-20 | 水溶性アセトアミノフェン類似体 |
| JP2014049672A Withdrawn JP2014111658A (ja) | 2008-05-20 | 2014-03-13 | 水溶性アセトアミノフェン類似体 |
| JP2016016971A Expired - Fee Related JP6063072B2 (ja) | 2008-05-20 | 2016-02-01 | 水溶性アセトアミノフェン類似体 |
| JP2016242968A Withdrawn JP2017057217A (ja) | 2008-05-20 | 2016-12-15 | 水溶性アセトアミノフェン類似体 |
| JP2018098716A Withdrawn JP2018135392A (ja) | 2008-05-20 | 2018-05-23 | 水溶性アセトアミノフェン類似体 |
| JP2020074690A Withdrawn JP2020114876A (ja) | 2008-05-20 | 2020-04-20 | 水溶性アセトアミノフェン類似体 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014049672A Withdrawn JP2014111658A (ja) | 2008-05-20 | 2014-03-13 | 水溶性アセトアミノフェン類似体 |
| JP2016016971A Expired - Fee Related JP6063072B2 (ja) | 2008-05-20 | 2016-02-01 | 水溶性アセトアミノフェン類似体 |
| JP2016242968A Withdrawn JP2017057217A (ja) | 2008-05-20 | 2016-12-15 | 水溶性アセトアミノフェン類似体 |
| JP2018098716A Withdrawn JP2018135392A (ja) | 2008-05-20 | 2018-05-23 | 水溶性アセトアミノフェン類似体 |
| JP2020074690A Withdrawn JP2020114876A (ja) | 2008-05-20 | 2020-04-20 | 水溶性アセトアミノフェン類似体 |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US20110212926A1 (https=) |
| EP (1) | EP2291348A4 (https=) |
| JP (6) | JP5757864B2 (https=) |
| KR (1) | KR101698028B1 (https=) |
| CN (2) | CN102149672A (https=) |
| AU (1) | AU2009249067A1 (https=) |
| BR (1) | BRPI0912326A2 (https=) |
| CA (1) | CA2724877C (https=) |
| IL (1) | IL209382A0 (https=) |
| MX (1) | MX2010012648A (https=) |
| RU (1) | RU2010151952A (https=) |
| WO (1) | WO2009143295A1 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2010151953A (ru) | 2008-05-20 | 2012-06-27 | Ньюроджесэкс, Инк. (Us) | Карбонатные продукты и способы их применения |
| KR101717145B1 (ko) | 2008-05-20 | 2017-03-16 | 노이로제스엑스, 인코포레이티드 | 간보호제 아세트아미노펜 공통 프로드러그 |
| KR101698028B1 (ko) | 2008-05-20 | 2017-01-26 | 노이로제스엑스, 인코포레이티드 | 수용성 아세트아미노펜 유사체 |
| EP2177215A1 (en) | 2008-10-17 | 2010-04-21 | Laboratorios Del. Dr. Esteve, S.A. | Co-crystals of tramadol and NSAIDs |
| WO2012137225A1 (en) * | 2011-04-08 | 2012-10-11 | Sphaera Pharma Pvt. Ltd | Substituted methylformyl reagents and method of using same to modify physicochemical and/or pharmacokinetic properties of compounds |
| AU2012312136B2 (en) | 2011-09-22 | 2017-06-29 | Acorda Therapeutics, Inc. | Acetaminophen conjugates, compositions and methods of use thereof |
| CA3042642A1 (en) | 2013-08-12 | 2015-02-19 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
| US10172797B2 (en) | 2013-12-17 | 2019-01-08 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| CA2955229C (en) | 2014-07-17 | 2020-03-10 | Pharmaceutical Manufacturing Research Services, Inc. | Immediate release abuse deterrent liquid fill dosage form |
| EP4578865A3 (en) | 2014-08-12 | 2025-07-30 | Monash University | Lymph directing prodrugs |
| WO2016064873A1 (en) | 2014-10-20 | 2016-04-28 | Pharmaceutical Manufacturing Research Services, Inc. | Extended release abuse deterrent liquid fill dosage form |
| RU2743347C2 (ru) | 2014-10-21 | 2021-02-17 | Эббви Инк. | Пролекарства карбидопа и l-dopa и их применение для лечения болезни паркинсона |
| EP3265097A4 (en) | 2015-03-03 | 2018-11-07 | Kindred Biosciences Inc. | Compositions and methods for treatment and prevention of pyrexia in horses |
| CA2997106C (en) | 2015-09-08 | 2024-06-04 | Monash University | Lymph directing prodrugs |
| EP3445346A1 (en) * | 2016-04-20 | 2019-02-27 | AbbVie Inc. | Carbidopa and l-dopa prodrugs and methods of use |
| EP3675838A4 (en) | 2017-08-29 | 2021-04-21 | PureTech LYT, Inc. | LIPID PRODRUGS DIRECTED TO THE LYMPHATIC SYSTEM |
| US11883497B2 (en) | 2017-08-29 | 2024-01-30 | Puretech Lyt, Inc. | Lymphatic system-directing lipid prodrugs |
| EP3727362A4 (en) | 2017-12-19 | 2021-10-06 | PureTech LYT, Inc. | MYCOPHENOLIC ACID LIPID PRODRUGS AND THEIR USES |
| US11304954B2 (en) | 2017-12-19 | 2022-04-19 | Puretech Lyt, Inc. | Lipid prodrugs of mycophenolic acid and uses thereof |
| US11608345B1 (en) | 2017-12-19 | 2023-03-21 | Puretech Lyt, Inc. | Lipid prodrugs of rapamycin and its analogs and uses thereof |
| EP3846852A4 (en) | 2018-09-07 | 2022-06-15 | R.P. Scherer Technologies, LLC | Solid or semisolid lipid based dosage form stabilization through curing and addition of low hlb surfactant(s) |
| CN113015531A (zh) | 2018-11-15 | 2021-06-22 | 艾伯维公司 | 用于皮下施用的药物调配物 |
| US11389409B2 (en) * | 2019-08-30 | 2022-07-19 | Remedy Diagnostics LLC | Transdermal device comprising acetaminophen prodrug |
| CN115348864A (zh) | 2020-02-05 | 2022-11-15 | 纯技术Lyt股份有限公司 | 神经甾体的脂质前药 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2444043A1 (fr) * | 1978-12-15 | 1980-07-11 | Bottu | Nouveau derive du paracetamol, son procede de preparation et son utilisation en therapeutique |
| DK406686D0 (da) * | 1986-08-26 | 1986-08-26 | Hans Bundgaard | Carboxylsyrederivater |
| US5001115A (en) * | 1989-05-17 | 1991-03-19 | University Of Florida | Prodrugs of biologically active hydroxyaromatic compounds |
| WO1991009831A1 (en) * | 1989-12-26 | 1991-07-11 | Nova Pharmaceutical Corporation | Prodrug anhydrides of asprin, indomethacin and ibuprofen, their preparation, compositions, and anti-inflammatory method of use |
| US5627165A (en) * | 1990-06-13 | 1997-05-06 | Drug Innovation & Design, Inc. | Phosphorous prodrugs and therapeutic delivery systems using same |
| US5272171A (en) * | 1992-02-13 | 1993-12-21 | Bristol-Myers Squibb Company | Phosphonooxy and carbonate derivatives of taxol |
| US6750216B2 (en) * | 1996-03-08 | 2004-06-15 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
| IT1282736B1 (it) * | 1996-05-21 | 1998-03-31 | Angelini Ricerche Spa | Uso di derivati del p-amminofenolo per preparare composizioni farmaceutiche utili nel trattamento di malattie neurodegenerative |
| DE69807464T2 (de) * | 1997-05-15 | 2003-05-15 | Drug Innovation & Design, Inc. | Diester-derivate von acyclovir |
| KR20010033811A (ko) * | 1997-12-31 | 2001-04-25 | 토마스 안 빅토리아 | 2차 및 3차 아민을 함유하는 약제의 물에 용해가능한프로드럭 및 그것의 제조방법 |
| PT1056754E (pt) * | 1998-01-29 | 2004-03-31 | Bristol Myers Squibb Co | Derivados fosfatados de 1,3,4-oxadiazolona de diarilo |
| US6204257B1 (en) | 1998-08-07 | 2001-03-20 | Universtiy Of Kansas | Water soluble prodrugs of hindered alcohols |
| US8231899B2 (en) * | 1998-09-10 | 2012-07-31 | Nycomed Danmark Aps | Quick release pharmaceutical compositions of drug substances |
| ATE232382T1 (de) * | 1998-09-10 | 2003-02-15 | Nycomed Danmark As | Pharmazeutische zusammensetzungen mit schneller freisetzung von wirkstoffen |
| US6461631B1 (en) * | 1999-11-16 | 2002-10-08 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
| US6362172B2 (en) | 2000-01-20 | 2002-03-26 | Bristol-Myers Squibb Company | Water soluble prodrugs of azole compounds |
| MXPA02009552A (es) * | 2000-03-29 | 2004-05-14 | Altana Pharma Ag | Derivados de imidazopiridina alquilada. |
| KR20040014544A (ko) * | 2001-06-05 | 2004-02-14 | 컨트롤 딜리버리 시스템즈 인코포레이티드 | 서방 진통제 화합물 |
| ATE373644T1 (de) * | 2002-02-05 | 2007-10-15 | Bristol Myers Squibb Co | N-substituierte 3-hydroxy-4-pyridinone und diese enthaltende pharmazeutika |
| US20040058946A1 (en) * | 2002-07-05 | 2004-03-25 | Buchwald Stephen L. | Abuse-resistant prodrugs of oxycodone and other pharmaceuticals |
| JP2006507322A (ja) * | 2002-11-14 | 2006-03-02 | シンタルガ・ビーブイ | 多重自己脱離放出スペーサーとして構築されたプロドラッグ |
| US20040186081A1 (en) * | 2003-03-03 | 2004-09-23 | Guilford Pharmaceuticals Inc. | Naaladase inhibitors for treating opioid tolerance |
| JP2006520392A (ja) * | 2003-03-13 | 2006-09-07 | コントロールド・ケミカルズ・インコーポレーテッド | 薬物の乱用可能性を低下させ且つ作用持続時間を延長する化合物および方法 |
| AU2003901813A0 (en) * | 2003-04-15 | 2003-05-01 | Vital Health Sciences Pty Ltd | Pharmaceutical derivatives |
| US20050080260A1 (en) * | 2003-04-22 | 2005-04-14 | Mills Randell L. | Preparation of prodrugs for selective drug delivery |
| US6992090B2 (en) * | 2003-06-16 | 2006-01-31 | Adolor Corporation | Substituted piperidine compounds and methods of their use |
| US20050026879A1 (en) * | 2003-07-31 | 2005-02-03 | Robinson Cynthia B. | Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a tyrosine kinase inhibitor, delta opioid receptor antagonist, neurokinin receptor antagonist, or VCAM inhibitor for treatment of asthma or chronic obstructive pulmonary disease |
| WO2005077394A1 (en) * | 2004-02-11 | 2005-08-25 | Ramot At Tel-Aviv University Ltd | Compositions for treatment of cancer and inflammation with curcumin and at least one nsaid |
| CN101023090B (zh) | 2004-07-06 | 2013-03-27 | 雅培制药有限公司 | Hiv蛋白酶抑制剂的前药 |
| CN101678120A (zh) | 2006-12-05 | 2010-03-24 | 纽罗吉斯克斯公司 | 前药及其制备和使用方法 |
| KR101698028B1 (ko) | 2008-05-20 | 2017-01-26 | 노이로제스엑스, 인코포레이티드 | 수용성 아세트아미노펜 유사체 |
| RU2010151953A (ru) | 2008-05-20 | 2012-06-27 | Ньюроджесэкс, Инк. (Us) | Карбонатные продукты и способы их применения |
| KR101717145B1 (ko) | 2008-05-20 | 2017-03-16 | 노이로제스엑스, 인코포레이티드 | 간보호제 아세트아미노펜 공통 프로드러그 |
| US8569466B2 (en) | 2008-09-10 | 2013-10-29 | Nnochiri Ekwuribe | Aromatic carboxylic acid derivatives for treatment and prophylaxis of gastrointestinal diseases including colon cancers |
| CA2755069A1 (en) | 2009-03-16 | 2010-09-23 | Genmedica Therapeutics Sl | Anti-inflammatory and antioxidant conjugates useful for treating metabolic disorders |
| AU2012312136B2 (en) | 2011-09-22 | 2017-06-29 | Acorda Therapeutics, Inc. | Acetaminophen conjugates, compositions and methods of use thereof |
-
2009
- 2009-05-20 KR KR1020107027998A patent/KR101698028B1/ko not_active Expired - Fee Related
- 2009-05-20 CA CA2724877A patent/CA2724877C/en not_active Expired - Fee Related
- 2009-05-20 CN CN2009801282182A patent/CN102149672A/zh active Pending
- 2009-05-20 EP EP09751523.3A patent/EP2291348A4/en not_active Withdrawn
- 2009-05-20 CN CN201510381430.7A patent/CN105254662A/zh active Pending
- 2009-05-20 AU AU2009249067A patent/AU2009249067A1/en not_active Abandoned
- 2009-05-20 JP JP2011510691A patent/JP5757864B2/ja not_active Expired - Fee Related
- 2009-05-20 MX MX2010012648A patent/MX2010012648A/es active IP Right Grant
- 2009-05-20 US US12/993,088 patent/US20110212926A1/en not_active Abandoned
- 2009-05-20 RU RU2010151952/04A patent/RU2010151952A/ru not_active Application Discontinuation
- 2009-05-20 WO PCT/US2009/044743 patent/WO2009143295A1/en not_active Ceased
- 2009-05-20 BR BRPI0912326A patent/BRPI0912326A2/pt not_active IP Right Cessation
-
2010
- 2010-11-17 IL IL209382A patent/IL209382A0/en unknown
-
2014
- 2014-03-13 JP JP2014049672A patent/JP2014111658A/ja not_active Withdrawn
-
2016
- 2016-02-01 JP JP2016016971A patent/JP6063072B2/ja not_active Expired - Fee Related
- 2016-03-22 US US15/077,802 patent/US9981998B2/en not_active Expired - Fee Related
- 2016-12-15 JP JP2016242968A patent/JP2017057217A/ja not_active Withdrawn
-
2018
- 2018-04-25 US US15/962,934 patent/US10442826B2/en not_active Expired - Fee Related
- 2018-05-23 JP JP2018098716A patent/JP2018135392A/ja not_active Withdrawn
-
2019
- 2019-09-09 US US16/565,173 patent/US11021498B2/en not_active Expired - Fee Related
-
2020
- 2020-04-20 JP JP2020074690A patent/JP2020114876A/ja not_active Withdrawn
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