JP2011518787A - 痙直及び振戦のような術後作用をクロニジンで治療する方法 - Google Patents

痙直及び振戦のような術後作用をクロニジンで治療する方法 Download PDF

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Publication number
JP2011518787A
JP2011518787A JP2011505218A JP2011505218A JP2011518787A JP 2011518787 A JP2011518787 A JP 2011518787A JP 2011505218 A JP2011505218 A JP 2011505218A JP 2011505218 A JP2011505218 A JP 2011505218A JP 2011518787 A JP2011518787 A JP 2011518787A
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Japan
Prior art keywords
clonidine
drug depot
depot
muscle
gel
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JP2011505218A
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English (en)
Japanese (ja)
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JP2011518787A5 (OSRAM
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キング，ヴァンジャ・マルガリータ
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Medtronic Inc
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Medtronic Inc
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Publication of JP2011518787A publication Critical patent/JP2011518787A/ja
Publication of JP2011518787A5 publication Critical patent/JP2011518787A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2011505218A 2008-04-18 2009-04-17 痙直及び振戦のような術後作用をクロニジンで治療する方法 Pending JP2011518787A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4619208P 2008-04-18 2008-04-18
US61/046,192 2008-04-18
US12/408,491 2009-03-20
US12/408,491 US20090263443A1 (en) 2008-04-18 2009-03-20 Methods for treating post-operative effects such as spasticity and shivering with clondine
PCT/US2009/040885 WO2009129428A2 (en) 2008-04-18 2009-04-17 Methods for treating post-operative effects such as spasticity and shivering with clonidine

Publications (2)

Publication Number Publication Date
JP2011518787A true JP2011518787A (ja) 2011-06-30
JP2011518787A5 JP2011518787A5 (OSRAM) 2012-01-19

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ID=41199746

Family Applications (1)

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JP2011505218A Pending JP2011518787A (ja) 2008-04-18 2009-04-17 痙直及び振戦のような術後作用をクロニジンで治療する方法

Country Status (5)

Country Link
US (1) US20090263443A1 (OSRAM)
EP (1) EP2207545B1 (OSRAM)
JP (1) JP2011518787A (OSRAM)
CN (1) CN101827592A (OSRAM)
WO (1) WO2009129428A2 (OSRAM)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021167331A (ja) * 2015-09-21 2021-10-21 テバ・ファーマシューティカルズ・インターナショナル・ゲーエムベーハーTeva Pharmaceuticals International GmbH 徐放性オランザピン製剤
US11813359B2 (en) 2017-03-20 2023-11-14 Teva Pharmaceuticals International Gmbh Sustained release olanzapine formulations

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE48948E1 (en) 2008-04-18 2022-03-01 Warsaw Orthopedic, Inc. Clonidine compounds in a biodegradable polymer
US20100239632A1 (en) 2009-03-23 2010-09-23 Warsaw Orthopedic, Inc. Drug depots for treatment of pain and inflammation in sinus and nasal cavities or cardiac tissue
US8623396B2 (en) 2010-12-03 2014-01-07 Warsaw Orthopedic, Inc. Compositions and methods for delivering clonidine and bupivacaine to a target tissue site
WO2012075451A2 (en) * 2010-12-03 2012-06-07 Warsaw Orthopedic, Inc. Clonidine and gaba compounds in a biodegradable polymer carrier
GB201505527D0 (en) 2015-03-31 2015-05-13 Jmedtech Pte Ltd Composition
WO2019071246A2 (en) 2017-10-06 2019-04-11 Foundry Therapeutics, Inc. IMPLANTABLE DEPOSITS FOR CONTROLLED RELEASE OF ANALGESICS TO TREAT POSTOPERATIVE PAIN, AND DEVICES, SYSTEMS, AND RELATED METHODS
US12364792B2 (en) 2018-01-08 2025-07-22 Foundry Therapeutics, Inc. Devices, systems, and methods for treating intraluminal cancer via controlled delivery of therapeutic agents
WO2019221853A1 (en) 2018-05-12 2019-11-21 Foundry Therapeutics, Inc. Implantable depots for the controlled release of therapeutic agents
WO2020047013A1 (en) 2018-08-28 2020-03-05 Foundry Therapeutics, Inc. Polymer implants

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005538952A (ja) * 2002-05-21 2005-12-22 アラーガン、インコーポレイテッド 痛みを緩和するための新規な方法および組成物
WO2006011915A1 (en) * 2004-06-30 2006-02-02 Allergan, Inc. Methods and compositions for the treatment of pain and other alpha 2 adrenergic-mediated conditions

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1248450A (en) * 1984-04-05 1989-01-10 Kazuo Kigasawa Soft patch
CN1156961A (zh) * 1995-06-09 1997-08-13 欧罗赛铁克股份有限公司 产生长效局部麻醉的制剂和方法
US6113624A (en) * 1995-10-02 2000-09-05 Ethicon, Inc. Absorbable elastomeric polymer
WO1998027963A2 (en) * 1996-12-20 1998-07-02 Alza Corporation Gel composition and methods
US6294170B1 (en) * 1997-08-08 2001-09-25 Amgen Inc. Composition and method for treating inflammatory diseases
TW577758B (en) * 1997-10-27 2004-03-01 Ssp Co Ltd Intra-articular preparation for the treatment of arthropathy
US6241736B1 (en) * 1998-05-12 2001-06-05 Scimed Life Systems, Inc. Manual bone anchor placement devices
US6632457B1 (en) * 1998-08-14 2003-10-14 Incept Llc Composite hydrogel drug delivery systems
US6927044B2 (en) * 1998-09-25 2005-08-09 Regeneron Pharmaceuticals, Inc. IL-1 receptor based cytokine traps
US6143314A (en) * 1998-10-28 2000-11-07 Atrix Laboratories, Inc. Controlled release liquid delivery compositions with low initial drug burst
US6565874B1 (en) * 1998-10-28 2003-05-20 Atrix Laboratories Polymeric delivery formulations of leuprolide with improved efficacy
US6436099B1 (en) * 1999-04-23 2002-08-20 Sdgi Holdings, Inc. Adjustable spinal tether
US7220281B2 (en) * 1999-08-18 2007-05-22 Intrinsic Therapeutics, Inc. Implant for reinforcing and annulus fibrosis
US7329529B2 (en) * 1999-09-03 2008-02-12 Millennium Pharmaceuticals, Inc. Ubiqutin proteases
US7951201B2 (en) * 1999-10-20 2011-05-31 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US6461631B1 (en) * 1999-11-16 2002-10-08 Atrix Laboratories, Inc. Biodegradable polymer composition
EP1244388B1 (en) * 1999-12-06 2007-01-17 Warsaw Orthopedic, Inc. Intervertebral disc treatment device
US6589549B2 (en) * 2000-04-27 2003-07-08 Macromed, Incorporated Bioactive agent delivering system comprised of microparticles within a biodegradable to improve release profiles
JP4184082B2 (ja) * 2001-01-03 2008-11-19 ボシュ・アンド・ロム・インコーポレイテッド 複数の薬剤を備えた徐放薬剤送達装置
US7229441B2 (en) * 2001-02-28 2007-06-12 Warsaw Orthopedic, Inc. Flexible systems for spinal stabilization and fixation
US7235043B2 (en) * 2001-03-09 2007-06-26 Boston Scientific Scimed Inc. System for implanting an implant and method thereof
MXPA01011542A (es) * 2001-11-13 2003-05-22 Alcon Inc Regeneracion del cartilago articular da°ado por la osteoartritis de grado i y ii, mediante la aplicacion intra-articular de una mezcla de hialuronato de sodio y de condroitin sulfato en un vehiculo de gel.
US6974462B2 (en) * 2001-12-19 2005-12-13 Boston Scientific Scimed, Inc. Surgical anchor implantation device
US8133501B2 (en) * 2002-02-08 2012-03-13 Boston Scientific Scimed, Inc. Implantable or insertable medical devices for controlled drug delivery
US20040109893A1 (en) * 2002-06-25 2004-06-10 Guohua Chen Sustained release dosage forms of anesthetics for pain management
CA2490007C (en) * 2002-07-19 2011-05-24 Omeros Corporation Biodegradable triblock copolymers, synthesis methods therefor, and hydrogels and biomaterials made there from
US20040166088A1 (en) * 2003-01-15 2004-08-26 Shalaby Shalaby W. Polymeric precursors of non-absorbable, in situ-forming hydrogels and applications thereof
KR20060023140A (ko) * 2003-05-30 2006-03-13 알자 코포레이션 이식성 탄성중합체 데포 조성물, 이의 용도 및 이의제조방법
US7144412B2 (en) * 2003-06-25 2006-12-05 Wolf Medical Enterprises, Inc. Gold suture and method of use in wound closure
US20050059744A1 (en) * 2003-09-12 2005-03-17 Allergan, Inc. Methods and compositions for the treatment of pain and other alpha 2 adrenergic-mediated conditions
WO2005046746A2 (en) * 2003-11-10 2005-05-26 Angiotech International Ag Medical implants and fibrosis-inducing agents
US20050175709A1 (en) * 2003-12-11 2005-08-11 Baty Ace M.Iii Therapeutic microparticles
JP2007519756A (ja) * 2004-01-30 2007-07-19 アンジオテック インターナショナル アーゲー 拘縮を治療するための組成物および方法
US7410480B2 (en) * 2004-04-21 2008-08-12 Acclarent, Inc. Devices and methods for delivering therapeutic substances for the treatment of sinusitis and other disorders
US7361168B2 (en) * 2004-04-21 2008-04-22 Acclarent, Inc. Implantable device and methods for delivering drugs and other substances to treat sinusitis and other disorders
US8741332B2 (en) * 2004-06-07 2014-06-03 Nuvo Research Inc. Compositions and methods for dermally treating neuropathic pain
US8512730B2 (en) * 2004-07-12 2013-08-20 Isto Technologies, Inc. Methods of tissue repair and compositions therefor
US20060046961A1 (en) * 2004-09-02 2006-03-02 Mckay William F Controlled and directed local delivery of anti-inflammatory compositions
US20060074422A1 (en) * 2004-09-27 2006-04-06 Story Brooks J Suture anchor and void filler combination
US20060253100A1 (en) * 2004-10-22 2006-11-09 Medtronic, Inc. Systems and Methods to Treat Pain Locally
EA200701131A1 (ru) * 2004-11-24 2007-12-28 Алгоркс Фармасьютикалз, Инк. Гелеобразная препаративная форма капсаициноида и способы её применения
US7611494B2 (en) * 2005-02-08 2009-11-03 Confluent Surgical, Inc. Spray for fluent materials
US20060183786A1 (en) * 2005-02-16 2006-08-17 Chi Mei Foundation Hospital Injectable long-acting analgesic composition comprising an ester derivative of ketorolac
AU2006249684A1 (en) * 2005-05-20 2006-11-30 Omeros Corporation Cyclooxygenase inhibitor and calcium channel antagonist compositions and methods for use in urological procedures
US7610100B2 (en) * 2005-12-30 2009-10-27 Boston Scientific Neuromodulation Corporation Methods and systems for treating osteoarthritis
US7741273B2 (en) * 2006-04-13 2010-06-22 Warsaw Orthopedic, Inc. Drug depot implant designs
US20070253994A1 (en) * 2006-04-28 2007-11-01 Medtronic, Inc. Intraspinal Drug Delivery Methods and Devices To Alleviate Chronic Pelvic Pain
US20080021074A1 (en) * 2006-06-29 2008-01-24 Questcor Pharmaceuticals, Inc. Pharmaceutical Compositions and Related Methods of Treatment
WO2008006117A2 (en) * 2006-07-07 2008-01-10 Bioassets Development Corporation Methods for preventing, postponing or improving the outcome of spinal device and fusion procedures
US20080091207A1 (en) * 2006-10-13 2008-04-17 Csaba Truckai Bone treatment systems and methods

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005538952A (ja) * 2002-05-21 2005-12-22 アラーガン、インコーポレイテッド 痛みを緩和するための新規な方法および組成物
WO2006011915A1 (en) * 2004-06-30 2006-02-02 Allergan, Inc. Methods and compositions for the treatment of pain and other alpha 2 adrenergic-mediated conditions

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN6013026468; ＡＮＥＳＴＨ．　ＡＮＡＬＧ． ＶＯＬ．９９, 2004, Ｐ．７１８-７２７ *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021167331A (ja) * 2015-09-21 2021-10-21 テバ・ファーマシューティカルズ・インターナショナル・ゲーエムベーハーTeva Pharmaceuticals International GmbH 徐放性オランザピン製剤
US11813359B2 (en) 2017-03-20 2023-11-14 Teva Pharmaceuticals International Gmbh Sustained release olanzapine formulations

Also Published As

Publication number Publication date
EP2207545A2 (en) 2010-07-21
US20090263443A1 (en) 2009-10-22
CN101827592A (zh) 2010-09-08
WO2009129428A3 (en) 2009-12-23
EP2207545A4 (en) 2012-02-15
EP2207545B1 (en) 2016-01-06
WO2009129428A2 (en) 2009-10-22

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