JP2011516544A5 - - Google Patents
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- Publication number
- JP2011516544A5 JP2011516544A5 JP2011503905A JP2011503905A JP2011516544A5 JP 2011516544 A5 JP2011516544 A5 JP 2011516544A5 JP 2011503905 A JP2011503905 A JP 2011503905A JP 2011503905 A JP2011503905 A JP 2011503905A JP 2011516544 A5 JP2011516544 A5 JP 2011516544A5
- Authority
- JP
- Japan
- Prior art keywords
- mitiglinide
- metformin
- test
- glufast
- tablets
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- WPGGHFDDFPHPOB-BBWFWOEESA-N Mitiglinide Chemical compound C([C@@H](CC(=O)N1C[C@@H]2CCCC[C@@H]2C1)C(=O)O)C1=CC=CC=C1 WPGGHFDDFPHPOB-BBWFWOEESA-N 0.000 claims description 12
- 229960003365 mitiglinide Drugs 0.000 claims description 12
- XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin Chemical compound CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 claims description 9
- 229960003105 Metformin Drugs 0.000 claims description 8
- 238000002360 preparation method Methods 0.000 claims description 7
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000007884 disintegrant Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000000314 lubricant Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- WPGGHFDDFPHPOB-UHFFFAOYSA-N Mitiglinide Chemical compound C1C2CCCCC2CN1C(=O)CC(C(=O)O)CC1=CC=CC=C1 WPGGHFDDFPHPOB-UHFFFAOYSA-N 0.000 description 4
- 230000000052 comparative effect Effects 0.000 description 4
- 239000008187 granular material Substances 0.000 description 4
- 229940095884 Glucophage Drugs 0.000 description 3
- 238000004090 dissolution Methods 0.000 description 3
- 238000007922 dissolution test Methods 0.000 description 3
- 238000010828 elution Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- AXCZMVOFGPJBDE-UHFFFAOYSA-L Calcium hydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 description 1
- 229960004329 Metformin hydrochloride Drugs 0.000 description 1
- 239000000920 calcium hydroxide Substances 0.000 description 1
- 235000011116 calcium hydroxide Nutrition 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 150000003840 hydrochlorides Chemical class 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 231100000486 side effect Toxicity 0.000 description 1
Images
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2008-0032673 | 2008-04-08 | ||
| KR1020080032673A KR101512386B1 (ko) | 2008-04-08 | 2008-04-08 | 미티글리나이드 및 메트포르민 복합제제 및 그의 제조방법 |
| PCT/KR2009/001809 WO2009125975A2 (ko) | 2008-04-08 | 2009-04-08 | 미티글리나이드 및 메트포르민 복합제제 및 그의 제조방법 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011516544A JP2011516544A (ja) | 2011-05-26 |
| JP2011516544A5 true JP2011516544A5 (hr) | 2013-08-01 |
Family
ID=41162388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011503905A Pending JP2011516544A (ja) | 2008-04-08 | 2009-04-08 | ミチグリニドおよびメトホルミンの複合製剤並びにその製造方法 |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JP2011516544A (hr) |
| KR (1) | KR101512386B1 (hr) |
| CN (1) | CN101990427A (hr) |
| TW (1) | TW200946111A (hr) |
| WO (1) | WO2009125975A2 (hr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110009347A1 (en) | 2009-07-08 | 2011-01-13 | Yin Liang | Combination therapy for the treatment of diabetes |
| PT2498758T (pt) * | 2009-11-13 | 2018-10-23 | Astrazeneca Uk Ltd | Formulações de comprimido bicamada |
| HUE029853T2 (en) | 2010-05-11 | 2017-04-28 | Janssen Pharmaceutica Nv | Pharmaceutical formulations containing 1- (beta-D-Glucopyranosyl) -2-thienylmethylbenzene derivatives as SGLT inhibitors |
| AU2011276332A1 (en) * | 2010-07-06 | 2013-01-17 | Janssen Pharmaceutica Nv | Formulation for co-therapy treatment of diabetes |
| KR101441355B1 (ko) * | 2013-05-29 | 2014-09-17 | 주식회사 다림바이오텍 | 레파글리니드 및 메트포르민을 함유하는 이층정 및 그의 제조방법 |
| CN110840855B (zh) * | 2019-11-27 | 2022-04-12 | 哈尔滨珍宝制药有限公司 | 依托考昔片及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1333887T3 (da) * | 2000-10-30 | 2006-11-13 | Ortho Mcneil Pharm Inc | Kombinationsbehandling omfattende antidiabetiske og antikonvulsive midler |
| KR100705210B1 (ko) * | 2004-09-23 | 2007-04-06 | 주식회사 한독약품 | 경구투여를 위한 당뇨병 치료용 약제학적 복합제제 |
| KR100760430B1 (ko) * | 2004-12-31 | 2007-10-04 | 한미약품 주식회사 | 당뇨병 치료제의 경구 투여용 서방성 복합 제제 및 이의제조 방법 |
| MXPA05010977A (es) * | 2005-10-12 | 2007-04-11 | Abdala Leopoldo Espinosa | Composiciones farmaceuticas que comprenden sustancias antidiabeticas combinadas para su uso en diabetes mellitus. |
| US20070172525A1 (en) * | 2007-03-15 | 2007-07-26 | Ramesh Sesha | Anti-diabetic combinations |
-
2008
- 2008-04-08 KR KR1020080032673A patent/KR101512386B1/ko active IP Right Grant
-
2009
- 2009-04-08 TW TW098111635A patent/TW200946111A/zh unknown
- 2009-04-08 JP JP2011503905A patent/JP2011516544A/ja active Pending
- 2009-04-08 WO PCT/KR2009/001809 patent/WO2009125975A2/ko active Application Filing
- 2009-04-08 CN CN2009801124437A patent/CN101990427A/zh active Pending
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