JP2011516045A - ポリケチドシンターゼを使用するジカルボン酸の生成法 - Google Patents

ポリケチドシンターゼを使用するジカルボン酸の生成法 Download PDF

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JP2011516045A
JP2011516045A JP2011502134A JP2011502134A JP2011516045A JP 2011516045 A JP2011516045 A JP 2011516045A JP 2011502134 A JP2011502134 A JP 2011502134A JP 2011502134 A JP2011502134 A JP 2011502134A JP 2011516045 A JP2011516045 A JP 2011516045A
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pks
domain
host cell
acid
dibasic acid
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JP2011516045A5 (https=
Inventor
レオナルド カッツ
ジェフリー エル． フォートマン
ジェイ ディー． キーズリング
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University of California
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University of California
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polyamides (AREA)
  • Polyesters Or Polycarbonates (AREA)
JP2011502134A 2008-03-28 2009-03-30 ポリケチドシンターゼを使用するジカルボン酸の生成法 Withdrawn JP2011516045A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4058408P 2008-03-28 2008-03-28
US61/040,584 2008-03-28
PCT/US2009/038831 WO2009121066A1 (en) 2008-03-28 2009-03-30 Producing dicarboxylic acids using polyketide synthases

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JP2011516045A true JP2011516045A (ja) 2011-05-26
JP2011516045A5 JP2011516045A5 (https=) 2012-05-24

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JP2011502134A Withdrawn JP2011516045A (ja) 2008-03-28 2009-03-30 ポリケチドシンターゼを使用するジカルボン酸の生成法

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US (2) US8569023B2 (https=)
EP (1) EP2254995A4 (https=)
JP (1) JP2011516045A (https=)
CN (1) CN101983239A (https=)
BR (1) BRPI0909839A2 (https=)
WO (1) WO2009121066A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014525741A (ja) * 2011-06-30 2014-10-02 インビスタ テクノロジーズ エス．アー．エール．エル． ナイロン−７、ナイロン−７，７、およびポリエステルを生産するための生物変換方法
WO2020032258A1 (ja) * 2018-08-10 2020-02-13 協和発酵バイオ株式会社 多価不飽和脂肪酸を生産する微生物及び多価不飽和脂肪酸の製造法

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US8569023B2 (en) * 2008-03-28 2013-10-29 The Regents Of The University Of California Producing dicarboxylic acids using polyketide synthases
JP2011519860A (ja) 2008-04-29 2011-07-14 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア ポリケチドシンターゼを使用するバイオ燃料の生成
ITMI20100753A1 (it) * 2010-04-30 2011-10-31 Dipharma Francis Srl Procedimento per la preparazione di statine
EP2383260A3 (en) * 2010-04-30 2011-12-28 Dipharma Francis S.r.l. Process for the preparation of statins
WO2012050931A2 (en) * 2010-09-28 2012-04-19 The Regents Of The University Of California Producing alpha-olefins using polyketide synthases
WO2012058686A2 (en) 2010-10-29 2012-05-03 The Regents Of The University Of California Hybrid polyketide synthases
US8852902B2 (en) 2010-11-22 2014-10-07 The Regents Of The University Of California Producing a trimethylpentanoic acid using hybrid polyketide synthases
WO2012071439A1 (en) * 2010-11-22 2012-05-31 The Regents Of The University Of California Host cells and methods for producing diacid compounds
CN103562398A (zh) 2011-03-22 2014-02-05 Opx生物工艺学公司 化学产品的微生物生产以及相关的组合物、方法和系统
EP2720997A1 (en) 2011-06-17 2014-04-23 Invista Technologies S.à.r.l. Use of hydrolases to increase monomer content in waste stream
DE102011110945A1 (de) 2011-08-15 2013-02-21 Evonik Degussa Gmbh Biotechnologisches Syntheseverfahren von organischen Verbindungen mit alkIL-Genprodukt
DE102011110946A1 (de) 2011-08-15 2016-01-21 Evonik Degussa Gmbh Biotechnologisches Syntheseverfahren von omegafunktionalisierten Carbonsäuren und Carbonsäure-Estern aus einfachen Kohlenstoffquellen
US9102958B2 (en) 2011-12-16 2015-08-11 Invista North America S.á.r.l. Methods of producing 6-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage
US9102960B2 (en) 2011-12-16 2015-08-11 Invista North America S.á.r.l. Methods of producing 6-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage
CN104126012A (zh) * 2011-12-21 2014-10-29 英威达技术有限责任公司 用于生产尼龙-7、尼龙-7,7和聚酯的生物转化工艺
SG11201501013PA (en) 2012-08-10 2015-04-29 Opx Biotechnologies Inc Microorganisms and methods for the production of fatty acids and fatty acid derived products
EP2735328A1 (en) * 2012-11-27 2014-05-28 PARI Pharma GmbH Fluid reservoir for an aerosol generation device, combination of fluid reservoir and primary fluid package, and aerosol generation device for use with the fluid reservoir
US9790525B2 (en) 2012-12-14 2017-10-17 Invista North America S.A.R.L. Methods of producing 7-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage
EP2938736A2 (en) 2012-12-31 2015-11-04 Invista Technologies S.A R.L. Methods of producing 7-carbon chemicals via c1 carbon chain elongation associated with coenzyme b synthesis
WO2014105793A1 (en) 2012-12-31 2014-07-03 Invista North America S.A.R.L. Methods of producing 7-carbon chemicals from long chain fatty acids via oxidative cleavage
EP2938734A2 (en) 2012-12-31 2015-11-04 Invista Technologies S.A R.L. Methods of producing 7-carbon chemicals via aromatic compounds
WO2014105797A2 (en) 2012-12-31 2014-07-03 Invista North America S.A.R.L. Methods of producing 7-carbon chemicals via pyruvate and succinate semialdehyde aldol condensation
CN105073214A (zh) 2012-12-31 2015-11-18 英威达技术有限责任公司 通过甲酯保护的碳链延伸生产6碳化学物的方法
EP2938731A2 (en) 2012-12-31 2015-11-04 Invista Technologies S.A R.L. Methods of producing 7-carbon chemicals via carbon chain elongation associated with cyclohexane carboxylate synthesis
CN105408487A (zh) 2012-12-31 2016-03-16 英威达技术有限责任公司 通过甲酯保护的碳链延伸生产7碳化学物的方法
WO2014146026A1 (en) 2013-03-15 2014-09-18 Opx Biotechnologies, Inc. Bioproduction of chemicals
CN106795483A (zh) 2013-07-19 2017-05-31 嘉吉公司 用于生产脂肪酸和脂肪酸衍生产物的微生物及方法
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
US10233431B2 (en) 2014-02-26 2019-03-19 The Regents Of The University Of California Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases
CN105085242A (zh) * 2014-05-25 2015-11-25 山东方明药业集团股份有限公司 一种优质丙酮二羧酸及丙酮二羧酸酯的合成方法
CN106795535A (zh) 2014-06-16 2017-05-31 英威达技术有限责任公司 用于生物合成化合物的方法，试剂和细胞
US20170152531A1 (en) 2014-06-16 2017-06-01 North America S.A.R.L. Process for producing glutarate and glutaric acid methyl ester
US9988654B2 (en) 2014-06-16 2018-06-05 Invista North America S.A.R.L. Methods, reagents and cells for biosynthesizing compounds
US9957535B2 (en) 2014-06-16 2018-05-01 Invista North America S.A.R.L. Methods, reagents and cells for biosynthesizing compounds
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
TWI613007B (zh) * 2015-06-08 2018-02-01 Ｉｈｉ股份有限公司 反應器
EP3577227A4 (en) 2017-02-02 2020-12-30 Cargill Inc. GENETICALLY MODIFIED CELLS PRODUCING C6-C10 FATTY ACID DERIVATIVES
WO2025140469A1 (en) * 2023-12-28 2025-07-03 Westlake University Bioengineering of modular polyketide synthases

Family Cites Families (8)

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US5672491A (en) 1993-09-20 1997-09-30 The Leland Stanford Junior University Recombinant production of novel polyketides
US5712146A (en) 1993-09-20 1998-01-27 The Leland Stanford Junior University Recombinant combinatorial genetic library for the production of novel polyketides
ES2164713T3 (es) 1993-09-20 2002-03-01 Univ Leland Stanford Junior Produccion recombinante de nuevos poliquetidos.
WO1998049315A2 (en) 1997-04-30 1998-11-05 Kosan Biosciences, Inc. Combinatorial polyketide libraries produced using a modular pks gene cluster as scaffold
IL122859A0 (en) 1995-07-06 1998-08-16 Univ Leland Stanford Junior Cell-free synthesis of polyketides
GB9814006D0 (en) * 1998-06-29 1998-08-26 Biotica Tech Ltd Polyketides and their synthesis
NZ511722A (en) 1998-11-20 2004-05-28 Kosan Biosciences Inc Recombinant methods and materials for producing epothilone and epothilone derivatives
US8569023B2 (en) * 2008-03-28 2013-10-29 The Regents Of The University Of California Producing dicarboxylic acids using polyketide synthases

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014525741A (ja) * 2011-06-30 2014-10-02 インビスタ テクノロジーズ エス．アー．エール．エル． ナイロン−７、ナイロン−７，７、およびポリエステルを生産するための生物変換方法
WO2020032258A1 (ja) * 2018-08-10 2020-02-13 協和発酵バイオ株式会社 多価不飽和脂肪酸を生産する微生物及び多価不飽和脂肪酸の製造法
JPWO2020032258A1 (ja) * 2018-08-10 2021-08-12 協和発酵バイオ株式会社 多価不飽和脂肪酸を生産する微生物及び多価不飽和脂肪酸の製造法
JP7540943B2 (ja) 2018-08-10 2024-08-27 協和発酵バイオ株式会社 多価不飽和脂肪酸を生産する微生物及び多価不飽和脂肪酸の製造法

Also Published As

Publication number Publication date
US8569023B2 (en) 2013-10-29
US9040282B2 (en) 2015-05-26
WO2009121066A1 (en) 2009-10-01
EP2254995A1 (en) 2010-12-01
EP2254995A4 (en) 2011-05-25
US20110014667A1 (en) 2011-01-20
US20140030789A1 (en) 2014-01-30
CN101983239A (zh) 2011-03-02
BRPI0909839A2 (pt) 2017-06-13

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