JP2011515490A5 - - Google Patents

Info

Publication number

JP2011515490A5

JP2011515490A5 JP2011502032A JP2011502032A JP2011515490A5 JP 2011515490 A5 JP2011515490 A5 JP 2011515490A5 JP 2011502032 A JP2011502032 A JP 2011502032A JP 2011502032 A JP2011502032 A JP 2011502032A JP 2011515490 A5 JP2011515490 A5 JP 2011515490A5

Authority

JP

Japan

Prior art keywords

vaccine

cldc

adjuvanted

fish

effective amount

Prior art date

2009-03-25

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• 229960005486 vaccine Drugs 0.000 claims 13
• 238000000034 method Methods 0.000 claims 11
• 241000124008 Mammalia Species 0.000 claims 9
• 241000251468 Actinopterygii Species 0.000 claims 8
• -1 cationic lipid Chemical class 0.000 claims 6
• 230000028993 immune response Effects 0.000 claims 5
• 238000001990 intravenous administration Methods 0.000 claims 5
• 241000271566 Aves Species 0.000 claims 3
• 102000035122 glycosylated proteins Human genes 0.000 claims 3
• 108091005608 glycosylated proteins Proteins 0.000 claims 3
• 238000007918 intramuscular administration Methods 0.000 claims 3
• 238000007920 subcutaneous administration Methods 0.000 claims 3
• 241000589601 Francisella Species 0.000 claims 2
• 239000002671 adjuvant Substances 0.000 claims 2
• 229940037003 alum Drugs 0.000 claims 2
• 239000000427 antigen Substances 0.000 claims 2
• 102000036639 antigens Human genes 0.000 claims 2
• 108091007433 antigens Proteins 0.000 claims 2
• 201000010099 disease Diseases 0.000 claims 2
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
• 239000002158 endotoxin Substances 0.000 claims 2
• 229960003971 influenza vaccine Drugs 0.000 claims 2
• 238000007912 intraperitoneal administration Methods 0.000 claims 2
• 229920006008 lipopolysaccharide Polymers 0.000 claims 2
• 229940035032 monophosphoryl lipid a Drugs 0.000 claims 2
• 229920001282 polysaccharide Polymers 0.000 claims 2
• 239000005017 polysaccharide Substances 0.000 claims 2
• 208000023275 Autoimmune disease Diseases 0.000 claims 1
• 208000035473 Communicable disease Diseases 0.000 claims 1
• 241000712431 Influenza A virus Species 0.000 claims 1
• 208000019693 Lung disease Diseases 0.000 claims 1
• 206010058467 Lung neoplasm malignant Diseases 0.000 claims 1
• RJQXTJLFIWVMTO-TYNCELHUSA-N Methicillin Chemical compound COC1=CC=CC(OC)=C1C(=O)N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@@H]21 RJQXTJLFIWVMTO-TYNCELHUSA-N 0.000 claims 1
• 206010028980 Neoplasm Diseases 0.000 claims 1
• 108091034117 Oligonucleotide Proteins 0.000 claims 1
• 241000191967 Staphylococcus aureus Species 0.000 claims 1
• 241001061127 Thione Species 0.000 claims 1
• 208000034784 Tularaemia Diseases 0.000 claims 1
• 201000009961 allergic asthma Diseases 0.000 claims 1
• 230000009285 allergic inflammation Effects 0.000 claims 1
• 208000006673 asthma Diseases 0.000 claims 1
• 201000011510 cancer Diseases 0.000 claims 1
• 150000004676 glycans Chemical class 0.000 claims 1
• 208000002672 hepatitis B Diseases 0.000 claims 1
• SPSXSWRZQFPVTJ-ZQQKUFEYSA-N hepatitis b vaccine Chemical compound C([C@H](NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CCSC)C(=O)N[C@@H](CC1N=CN=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)OC(=O)CNC(=O)CNC(=O)[C@H](C)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@@H](N)CCCNC(N)=N)C1=CC=CC=C1 SPSXSWRZQFPVTJ-ZQQKUFEYSA-N 0.000 claims 1
• 229940124736 hepatitis-B vaccine Drugs 0.000 claims 1
• 229940124739 inactivated trivalent influenza vaccine Drugs 0.000 claims 1
• 230000001939 inductive effect Effects 0.000 claims 1
• 208000015181 infectious disease Diseases 0.000 claims 1
• 150000002632 lipids Chemical class 0.000 claims 1
• 201000005202 lung cancer Diseases 0.000 claims 1
• 208000020816 lung neoplasm Diseases 0.000 claims 1
• 230000001394 metastastic effect Effects 0.000 claims 1
• 206010061289 metastatic neoplasm Diseases 0.000 claims 1
• 229960003085 meticillin Drugs 0.000 claims 1
• 229940023143 protein vaccine Drugs 0.000 claims 1
• 102000004169 proteins and genes Human genes 0.000 claims 1
• 108090000623 proteins and genes Proteins 0.000 claims 1
• 230000004936 stimulating effect Effects 0.000 claims 1
• 241000712461 unidentified influenza virus Species 0.000 claims 1
• 230000003612 virological effect Effects 0.000 claims 1