JP2011515078A5 - - Google Patents
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- Publication number
- JP2011515078A5 JP2011515078A5 JP2010549777A JP2010549777A JP2011515078A5 JP 2011515078 A5 JP2011515078 A5 JP 2011515078A5 JP 2010549777 A JP2010549777 A JP 2010549777A JP 2010549777 A JP2010549777 A JP 2010549777A JP 2011515078 A5 JP2011515078 A5 JP 2011515078A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- cancer
- mirna
- nucleic acid
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3296108P | 2008-03-01 | 2008-03-01 | |
| US61/032,961 | 2008-03-01 | ||
| PCT/US2009/035660 WO2009111375A2 (en) | 2008-03-01 | 2009-03-02 | Treatment, diagnostic, and method for discovering antagonist using sparc specific mirnas |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011515078A JP2011515078A (ja) | 2011-05-19 |
| JP2011515078A5 true JP2011515078A5 (https=) | 2011-09-22 |
Family
ID=40707714
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010549777A Pending JP2011515078A (ja) | 2008-03-01 | 2009-03-02 | SPARC特異的miRNAを使用する、治療、診断、及び拮抗物質発見方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20090220589A1 (https=) |
| EP (1) | EP2257626A2 (https=) |
| JP (1) | JP2011515078A (https=) |
| AU (1) | AU2009222056A1 (https=) |
| CA (1) | CA2717169A1 (https=) |
| WO (1) | WO2009111375A2 (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2390425T3 (es) * | 2000-12-22 | 2012-11-12 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Uso de moléculas de orientación repulsivas (RGM) y sus moduladores |
| CN101277974A (zh) | 2005-09-30 | 2008-10-01 | 阿伯特有限及两合公司 | 排斥性引导分子(rgm)蛋白质家族的蛋白质的结合结构域及其功能性片段和它们的用途 |
| EP2487258B1 (en) | 2006-01-05 | 2014-10-01 | The Ohio State University Research Foundation | MicroRNA-based methods for the diagnosis of colon, pancreas and stomach cancer |
| ES2446362T3 (es) | 2006-03-20 | 2014-03-07 | The Ohio State University Research Foundation | Huellas de microARN durante megacariocipoyesis humana |
| AU2008283795B2 (en) | 2007-07-31 | 2013-11-21 | Board Of Regents, The University Of Texas System | A micro-RNA family that modulates fibrosis and uses thereof |
| JP2010535473A (ja) | 2007-08-03 | 2010-11-25 | ズィ、オハイオウ、ステイト、ユーニヴァーサティ、リサーチ、ファウンデイシャン | ncRNAをコードする超保存領域 |
| WO2009108853A1 (en) * | 2008-02-28 | 2009-09-03 | The Ohio State University Research Foundation | MicroRNA-BASED METHODS AND COMPOSITIONS FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF GASTRIC CANCER |
| US8962803B2 (en) | 2008-02-29 | 2015-02-24 | AbbVie Deutschland GmbH & Co. KG | Antibodies against the RGM A protein and uses thereof |
| CA2718520C (en) | 2008-03-17 | 2020-01-07 | The Board Of Regents Of The University Of Texas System | Identification of micro-rnas involved in neuromuscular synapse maintenance and regeneration |
| WO2011043739A1 (en) * | 2009-10-09 | 2011-04-14 | Singapore Health Services Pte. Ltd. | Methods and compositions for maintenance of a functional wound |
| US8916533B2 (en) | 2009-11-23 | 2014-12-23 | The Ohio State University | Materials and methods useful for affecting tumor cell growth, migration and invasion |
| CN102656190A (zh) | 2009-12-08 | 2012-09-05 | 雅培股份有限两合公司 | 用于在视网膜神经纤维层变性治疗中使用的针对rgm a蛋白质的单克隆抗体 |
| US20130131148A1 (en) * | 2010-04-12 | 2013-05-23 | Noam Shomron | Micro-rna for cancer diagnosis, prognosis and therapy |
| WO2011130464A1 (en) * | 2010-04-14 | 2011-10-20 | Abraxis Bioscience, Llc | Translational regulation of sparc by the micrornas mir29a, b and c |
| US20130139273A1 (en) * | 2010-06-24 | 2013-05-30 | The Ohio State University | Chronic Lymphocytic Leukemia Modeled in Mouse by Targeted miR-29 Expression |
| WO2012006181A2 (en) * | 2010-06-29 | 2012-01-12 | Mount Sinai School Of Medicine | Compositions and methods for inhibiting oncogenic micrornas and treatment of cancer |
| CN102382823B (zh) * | 2010-09-01 | 2013-04-24 | 中国科学院上海药物研究所 | 人miR-515-5p反义核酸及其应用 |
| JP5931897B2 (ja) | 2010-11-12 | 2016-06-08 | ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイションThe Ohio State University Research Foundation | マイクロrna−21、ミスマッチ修復および結腸直腸癌に関連する物質および方法 |
| CA2817982C (en) | 2010-11-15 | 2020-06-30 | The Regents Of The University Of Michigan | Controlled release mucoadhesive systems |
| WO2012093384A1 (en) * | 2011-01-03 | 2012-07-12 | Rosetta Genomics Ltd. | Compositions and methods for treatment of ovarian cancer |
| TWI421084B (zh) * | 2011-04-01 | 2014-01-01 | Univ Kaohsiung Medical | 微小RNA let-7g的新用途 |
| AU2012323924A1 (en) | 2011-10-14 | 2014-05-29 | The Ohio State University | Methods and materials related to ovarian cancer |
| CA2859430A1 (en) | 2011-12-13 | 2013-06-20 | Ohio State Innovation Foundation | Methods and compositions related to mir-21 and mir-29a, exosome inhibition, and cancer metastasis |
| US8859202B2 (en) | 2012-01-20 | 2014-10-14 | The Ohio State University | Breast cancer biomarker signatures for invasiveness and prognosis |
| NZ714482A (en) | 2012-01-27 | 2017-08-25 | Abbvie Inc | Composition and method for diagnosis and treatment of diseases associated with neurite degeneration |
| JP6129544B2 (ja) * | 2012-12-18 | 2017-05-17 | 花王株式会社 | Sparc産生促進剤 |
| JP6571663B2 (ja) * | 2013-09-14 | 2019-09-04 | ケムジーンズ コーポレーション | 逆方向アプローチを使用した長いrnaの非常に効果的な合成 |
| WO2017062659A1 (en) * | 2015-10-06 | 2017-04-13 | University Of Virginia Patent Foundation | Compositions and methods for treating diabetic retinopathy |
| CN107858416B (zh) * | 2016-09-19 | 2021-05-28 | 深圳华大生命科学研究院 | 用于子宫内膜异位症检测的生物标志物组合及其应用 |
| EP3820483A4 (en) * | 2018-07-13 | 2023-03-01 | Yale University | COMPOSITIONS AND METHODS FOR THE TREATMENT OF ENDOMETRIOSIS |
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| US3854480A (en) * | 1969-04-01 | 1974-12-17 | Alza Corp | Drug-delivery system |
| US3852253A (en) * | 1972-12-22 | 1974-12-03 | Exxon Research Engineering Co | Heterogeneous process for preparing conjugated diene butyl |
| US4675189A (en) * | 1980-11-18 | 1987-06-23 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble active polypeptides |
| US4452775A (en) * | 1982-12-03 | 1984-06-05 | Syntex (U.S.A.) Inc. | Cholesterol matrix delivery system for sustained release of macromolecules |
| CA1200416A (en) * | 1983-05-13 | 1986-02-11 | Societe Des Produits Nestle S.A. | Food process |
| US4667013A (en) * | 1986-05-02 | 1987-05-19 | Union Carbide Corporation | Process for alkylene oxide polymerization |
| US5075109A (en) * | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
| US5133974A (en) * | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
| ATE269870T1 (de) * | 1989-10-24 | 2004-07-15 | Isis Pharmaceuticals Inc | 2'-modifizierte oligonukleotide |
| ATE174058T1 (de) * | 1989-11-06 | 1998-12-15 | Cell Genesys Inc | Herstellung von proteinen mittels homologer rekombination |
| US5272071A (en) * | 1989-12-22 | 1993-12-21 | Applied Research Systems Ars Holding N.V. | Method for the modification of the expression characteristics of an endogenous gene of a given cell line |
| US5378825A (en) * | 1990-07-27 | 1995-01-03 | Isis Pharmaceuticals, Inc. | Backbone modified oligonucleotide analogs |
| US5223618A (en) * | 1990-08-13 | 1993-06-29 | Isis Pharmaceuticals, Inc. | 4'-desmethyl nucleoside analog compounds |
| US5610289A (en) * | 1990-07-27 | 1997-03-11 | Isis Pharmaceuticals, Inc. | Backbone modified oligonucleotide analogues |
| US5623070A (en) * | 1990-07-27 | 1997-04-22 | Isis Pharmaceuticals, Inc. | Heteroatomic oligonucleoside linkages |
| US5602240A (en) * | 1990-07-27 | 1997-02-11 | Ciba Geigy Ag. | Backbone modified oligonucleotide analogs |
| BR9106702A (pt) * | 1990-07-27 | 1993-06-08 | Isis Pharmaceuticals Inc | Analogo de oligonucleotideos e processos para modular a producao de uma proteina por um organismo e para tratar um organismo |
| JPH04167172A (ja) * | 1990-10-31 | 1992-06-15 | Nec Corp | ベクトルプロセッサ |
| US5672697A (en) * | 1991-02-08 | 1997-09-30 | Gilead Sciences, Inc. | Nucleoside 5'-methylene phosphonates |
| US5407686A (en) * | 1991-11-27 | 1995-04-18 | Sidmak Laboratories, Inc. | Sustained release composition for oral administration of active ingredient |
| US5489743A (en) * | 1993-01-19 | 1996-02-06 | Amgen Inc. | Transgenic animal models for thrombocytopenia |
| US5858988A (en) * | 1993-02-24 | 1999-01-12 | Wang; Jui H. | Poly-substituted-phenyl-oligoribo nucleotides having enhanced stability and membrane permeability and methods of use |
| US5519134A (en) * | 1994-01-11 | 1996-05-21 | Isis Pharmaceuticals, Inc. | Pyrrolidine-containing monomers and oligomers |
| US5705629A (en) * | 1995-10-20 | 1998-01-06 | Hybridon, Inc. | Methods for H-phosphonate synthesis of mono- and oligonucleotides |
| US5736152A (en) * | 1995-10-27 | 1998-04-07 | Atrix Laboratories, Inc. | Non-polymeric sustained release delivery system |
| US6919208B2 (en) * | 2000-05-22 | 2005-07-19 | The Children's Hospital Of Philadelphia | Methods and compositions for enhancing the delivery of a nucleic acid to a cell |
| EP2295604B1 (en) * | 2004-02-09 | 2015-04-08 | Thomas Jefferson University | Diagnosis and treatment of cancers with microRNA located in or near cancer-associated chromosomal features |
| US8420603B2 (en) * | 2004-05-14 | 2013-04-16 | Abraxis Bioscience, Llc | SPARC and methods of use thereof |
| US7332568B2 (en) * | 2005-02-18 | 2008-02-19 | Abraxis Bioscience, Inc. | Q3 SPARC deletion mutant and uses thereof |
| CA2657030A1 (en) * | 2006-07-13 | 2008-01-17 | The Ohio State University Research Foundation, An Instrumentality Of The State Of Ohio | Micro-rna-based methods and compositions for the diagnosis and treatment of colon cancer-related diseases |
| US8466117B2 (en) * | 2006-07-28 | 2013-06-18 | The Johns Hopkins University | Compositions and methods for modulating angiogenesis |
-
2009
- 2009-03-02 WO PCT/US2009/035660 patent/WO2009111375A2/en not_active Ceased
- 2009-03-02 CA CA2717169A patent/CA2717169A1/en not_active Abandoned
- 2009-03-02 EP EP09717085A patent/EP2257626A2/en not_active Withdrawn
- 2009-03-02 JP JP2010549777A patent/JP2011515078A/ja active Pending
- 2009-03-02 US US12/395,872 patent/US20090220589A1/en not_active Abandoned
- 2009-03-02 AU AU2009222056A patent/AU2009222056A1/en not_active Abandoned
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