JP2011514139A5 - - Google Patents
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- Publication number
- JP2011514139A5 JP2011514139A5 JP2010523277A JP2010523277A JP2011514139A5 JP 2011514139 A5 JP2011514139 A5 JP 2011514139A5 JP 2010523277 A JP2010523277 A JP 2010523277A JP 2010523277 A JP2010523277 A JP 2010523277A JP 2011514139 A5 JP2011514139 A5 JP 2011514139A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- polyclonal
- cell line
- individual
- rsv
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims 7
- 238000000034 method Methods 0.000 claims 5
- 238000004519 manufacturing process Methods 0.000 claims 3
- 238000012258 culturing Methods 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 108010068327 4-hydroxyphenylpyruvate dioxygenase Proteins 0.000 claims 1
- 108091006027 G proteins Proteins 0.000 claims 1
- 102000030782 GTP binding Human genes 0.000 claims 1
- 108091000058 GTP-Binding Proteins 0.000 claims 1
- 230000003321 amplification Effects 0.000 claims 1
- 238000003491 array Methods 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 230000010354 integration Effects 0.000 claims 1
- 238000003199 nucleic acid amplification method Methods 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- 238000001890 transfection Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200701289 | 2007-09-07 | ||
| US97140407P | 2007-09-11 | 2007-09-11 | |
| PCT/DK2008/050218 WO2009030237A2 (en) | 2007-09-07 | 2008-09-04 | Methods for recombinant manufacturing of anti-rsv antibodies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011514139A JP2011514139A (ja) | 2011-05-06 |
| JP2011514139A5 true JP2011514139A5 (https=) | 2012-11-08 |
Family
ID=40297785
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010523277A Pending JP2011514139A (ja) | 2007-09-07 | 2008-09-04 | 抗ｒｓｖ抗体の組み換え製造のための方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20090137003A1 (https=) |
| EP (1) | EP2185590A2 (https=) |
| JP (1) | JP2011514139A (https=) |
| KR (1) | KR20100087283A (https=) |
| CN (1) | CN101821289A (https=) |
| AU (1) | AU2008295248A1 (https=) |
| BR (1) | BRPI0817079A2 (https=) |
| CA (1) | CA2695309A1 (https=) |
| MX (1) | MX2010002044A (https=) |
| RU (1) | RU2010113510A (https=) |
| TW (1) | TW200925279A (https=) |
| WO (1) | WO2009030237A2 (https=) |
| ZA (1) | ZA201000756B (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2444695T3 (es) * | 2006-06-23 | 2014-02-26 | Alethia Biotherapeutics Inc. | Polinucleótidos y polipéptidos implicados en el cáncer |
| DK2121920T3 (da) * | 2007-03-01 | 2011-11-21 | Symphogen As | Fremgangsmåde til kloning af sammenhørende antistoffer |
| EP1997830A1 (en) | 2007-06-01 | 2008-12-03 | AIMM Therapeutics B.V. | RSV specific binding molecules and means for producing them |
| CN102137928A (zh) * | 2008-08-29 | 2011-07-27 | 西福根有限公司 | 克隆禽源抗体的方法 |
| CA2740900C (en) | 2008-11-03 | 2019-09-24 | Alethia Biotherapeutics Inc. | Antibodies that specifically block the biological activity of a tumor antigen |
| GB0905023D0 (en) | 2009-03-24 | 2009-05-06 | Univ Erasmus Medical Ct | Binding molecules |
| JP5762408B2 (ja) * | 2009-08-13 | 2015-08-12 | クルセル ホランド ベー ヴェー | ヒト呼吸器合胞体ウイルス（ｒｓｖ）に対する抗体および使用方法 |
| EP2486053B1 (en) * | 2009-10-06 | 2017-01-18 | Medimmune Limited | Rsv-specific binding molecule |
| US8568726B2 (en) | 2009-10-06 | 2013-10-29 | Medimmune Limited | RSV specific binding molecule |
| CN104628850B (zh) * | 2009-10-06 | 2020-07-28 | 医学免疫有限公司 | Rsv-特异性结合分子 |
| ES2724975T3 (es) | 2009-12-10 | 2019-09-18 | Regeneron Pharma | Ratones que producen anticuerpos de cadena pesada |
| BR112012031638B1 (pt) | 2010-07-09 | 2021-01-12 | Janssen Vaccines & Prevention B.V. | anticorpo anti-rsv ou fragmento de ligação de antígeno do mesmo, anticorpo multivalente, composição farmacêutica, uso de anticorpo ou fragmento de ligação de antígeno, método de detectar infecção por rsv, e, ácido nucleico isolado |
| SI3173427T1 (sl) | 2011-03-31 | 2019-08-30 | ADC Therapeutics SA, | Protitelesa proti antigenu 1, povezanemu z ledvicami, in antigen vezavni fragmenti le-tega |
| KR102102239B1 (ko) | 2012-01-09 | 2020-04-21 | 에이디씨 테라퓨틱스 에스에이 | 유방암을 치료하기 위한 방법 |
| TWI606063B (zh) * | 2012-08-23 | 2017-11-21 | 艾澤西公司 | 結合至１５８ｐ１ｄ７蛋白之抗體藥物結合物（ａｄｃ） |
| JP5996707B2 (ja) * | 2015-04-15 | 2016-09-21 | メディミューン リミテド | Ｒｓｖ特異的結合分子 |
| SG11201708804WA (en) | 2015-05-07 | 2017-11-29 | Agenus Inc | Anti-ox40 antibodies and methods of use thereof |
| MA43389A (fr) * | 2015-12-02 | 2021-05-12 | Agenus Inc | Anticorps anti-ox40 et leurs procédés d'utilisation |
| AU2016364891A1 (en) * | 2015-12-03 | 2018-06-07 | Agenus Inc. | Anti-OX40 antibodies and methods of use thereof |
| CN110035771B (zh) * | 2016-10-21 | 2024-03-08 | 阿迪马布有限责任公司 | 抗呼吸道合胞病毒抗体及其产生和使用方法 |
| AU2017345786B2 (en) | 2016-10-21 | 2024-08-01 | Adimab, Llc | Anti-respiratory syncytial virus antibodies, and methods of their generation and use |
| US11479600B2 (en) | 2016-10-21 | 2022-10-25 | Adimab, Llc | Anti-respiratory syncytial virus antibodies, and methods of their generation and use |
| MA46770A (fr) | 2016-11-09 | 2019-09-18 | Agenus Inc | Anticorps anti-ox40, anticorps anti-gitr, et leurs procédés d'utilisation |
| WO2018150029A1 (en) * | 2017-02-17 | 2018-08-23 | Institut Pasteur | Generation of monoclonal antibodies targeting respiratory syncytial virus (rsv) using regulatory b cells from newborns (nbregs) |
| CN113728003A (zh) | 2019-04-30 | 2021-11-30 | 吉加根公司 | 重组多克隆蛋白及其使用方法 |
| WO2021202463A1 (en) | 2020-03-30 | 2021-10-07 | Danisco Us Inc | Anti-rsv antibodies |
| WO2021253002A1 (en) | 2020-06-12 | 2021-12-16 | Gigagen, Inc. | Recombinant polyclonal proteins targeting covid-19 and methods of use thereof |
| WO2022031834A1 (en) * | 2020-08-05 | 2022-02-10 | Gigagen, Inc. | Recombinant polyclonal proteins targeting zika and methods of use thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060275766A1 (en) * | 2003-01-07 | 2006-12-07 | Haurum John S | Method for manufacturing recombinant polyclonal proteins |
| TWI333977B (en) * | 2003-09-18 | 2010-12-01 | Symphogen As | Method for linking sequences of interest |
| US8288109B2 (en) * | 2004-07-20 | 2012-10-16 | Symphogen A/S | Procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line |
| EA014182B1 (ru) * | 2004-07-20 | 2010-10-29 | Симфоген А/С | КОМПОЗИЦИЯ ПОЛИКЛОНАЛЬНЫХ АНТИ-RhD АНТИТЕЛ, СПОСОБ ЕЁ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЕ КОМПОЗИЦИИ |
| US7850965B2 (en) * | 2005-12-05 | 2010-12-14 | Symphogen A/S | Anti-orthopoxvirus recombinant polyclonal antibody |
| WO2007101441A1 (en) * | 2006-03-06 | 2007-09-13 | Symphogen A/S | Recombinant polyclonal antibody for treatment of respiratory syncytial virus infections |
| JP2010534057A (ja) * | 2007-03-06 | 2010-11-04 | シムフォゲン・アクティーゼルスカブ | 呼吸器合胞体ウイルス感染症を治療するための組換え抗体 |
| MX2009012526A (es) * | 2007-05-25 | 2009-12-09 | Symphogen As | Metodo para fabricar una proteina policlonal recombinante. |
-
2008
- 2008-09-04 CA CA2695309A patent/CA2695309A1/en not_active Abandoned
- 2008-09-04 RU RU2010113510/10A patent/RU2010113510A/ru not_active Application Discontinuation
- 2008-09-04 EP EP08784476A patent/EP2185590A2/en not_active Withdrawn
- 2008-09-04 AU AU2008295248A patent/AU2008295248A1/en not_active Abandoned
- 2008-09-04 JP JP2010523277A patent/JP2011514139A/ja active Pending
- 2008-09-04 MX MX2010002044A patent/MX2010002044A/es not_active Application Discontinuation
- 2008-09-04 WO PCT/DK2008/050218 patent/WO2009030237A2/en not_active Ceased
- 2008-09-04 KR KR1020107007563A patent/KR20100087283A/ko not_active Withdrawn
- 2008-09-04 CN CN200880106131A patent/CN101821289A/zh active Pending
- 2008-09-04 BR BRPI0817079A patent/BRPI0817079A2/pt not_active IP Right Cessation
- 2008-09-05 TW TW097134053A patent/TW200925279A/zh unknown
- 2008-09-05 US US12/230,885 patent/US20090137003A1/en not_active Abandoned
-
2010
- 2010-02-01 ZA ZA2010/00756A patent/ZA201000756B/en unknown
-
2011
- 2011-09-23 US US13/243,768 patent/US20120009623A1/en not_active Abandoned