JP2011513356A5 - - Google Patents
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- Publication number
- JP2011513356A5 JP2011513356A5 JP2010549109A JP2010549109A JP2011513356A5 JP 2011513356 A5 JP2011513356 A5 JP 2011513356A5 JP 2010549109 A JP2010549109 A JP 2010549109A JP 2010549109 A JP2010549109 A JP 2010549109A JP 2011513356 A5 JP2011513356 A5 JP 2011513356A5
- Authority
- JP
- Japan
- Prior art keywords
- zinc
- trimethoprim
- infection
- composition according
- viral infection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 16
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims 10
- IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 claims 10
- 229960001082 trimethoprim Drugs 0.000 claims 10
- 239000011701 zinc Substances 0.000 claims 10
- 229910052725 zinc Inorganic materials 0.000 claims 10
- 230000009385 viral infection Effects 0.000 claims 9
- 208000036142 Viral infection Diseases 0.000 claims 8
- 206010062106 Respiratory tract infection viral Diseases 0.000 claims 3
- 241000700605 Viruses Species 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 241000711573 Coronaviridae Species 0.000 claims 2
- 241000709661 Enterovirus Species 0.000 claims 2
- 208000002606 Paramyxoviridae Infections Diseases 0.000 claims 2
- 241000709664 Picornaviridae Species 0.000 claims 2
- 241000725643 Respiratory syncytial virus Species 0.000 claims 2
- 230000000840 anti-viral effect Effects 0.000 claims 2
- -1 carrier Substances 0.000 claims 2
- 238000000576 coating method Methods 0.000 claims 2
- 239000000499 gel Substances 0.000 claims 2
- 208000037797 influenza A Diseases 0.000 claims 2
- 208000037798 influenza B Diseases 0.000 claims 2
- 238000013268 sustained release Methods 0.000 claims 2
- 239000012730 sustained-release form Substances 0.000 claims 2
- 241000701161 unidentified adenovirus Species 0.000 claims 2
- 150000003751 zinc Chemical class 0.000 claims 2
- WHMDKBIGKVEYHS-IYEMJOQQSA-L Zinc gluconate Chemical compound [Zn+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O WHMDKBIGKVEYHS-IYEMJOQQSA-L 0.000 claims 1
- ZOIORXHNWRGPMV-UHFFFAOYSA-N acetic acid;zinc Chemical compound [Zn].CC(O)=O.CC(O)=O ZOIORXHNWRGPMV-UHFFFAOYSA-N 0.000 claims 1
- 230000001154 acute effect Effects 0.000 claims 1
- 239000000654 additive Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 239000000443 aerosol Substances 0.000 claims 1
- 230000000202 analgesic effect Effects 0.000 claims 1
- 239000011230 binding agent Substances 0.000 claims 1
- 239000000227 bioadhesive Substances 0.000 claims 1
- 239000000872 buffer Substances 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 230000003111 delayed effect Effects 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000002662 enteric coated tablet Substances 0.000 claims 1
- 239000003889 eye drop Substances 0.000 claims 1
- 229940012356 eye drops Drugs 0.000 claims 1
- 239000000796 flavoring agent Substances 0.000 claims 1
- 235000013355 food flavoring agent Nutrition 0.000 claims 1
- 235000003599 food sweetener Nutrition 0.000 claims 1
- 239000003906 humectant Substances 0.000 claims 1
- 230000002209 hydrophobic effect Effects 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 210000004185 liver Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 210000003205 muscle Anatomy 0.000 claims 1
- 239000007923 nasal drop Substances 0.000 claims 1
- 229940100662 nasal drops Drugs 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000006187 pill Substances 0.000 claims 1
- 239000002798 polar solvent Substances 0.000 claims 1
- 238000006116 polymerization reaction Methods 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 239000003765 sweetening agent Substances 0.000 claims 1
- 239000006188 syrup Substances 0.000 claims 1
- 235000020357 syrup Nutrition 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
- 230000007704 transition Effects 0.000 claims 1
- 241000712461 unidentified influenza virus Species 0.000 claims 1
- 208000020017 viral respiratory tract infection Diseases 0.000 claims 1
- 239000011782 vitamin Substances 0.000 claims 1
- 229940088594 vitamin Drugs 0.000 claims 1
- 229930003231 vitamin Natural products 0.000 claims 1
- 235000013343 vitamin Nutrition 0.000 claims 1
- 150000003722 vitamin derivatives Chemical class 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 239000004246 zinc acetate Substances 0.000 claims 1
- 229960000306 zinc gluconate Drugs 0.000 claims 1
- 239000011670 zinc gluconate Substances 0.000 claims 1
- 235000011478 zinc gluconate Nutrition 0.000 claims 1
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 claims 1
- 229960001763 zinc sulfate Drugs 0.000 claims 1
- 229910000368 zinc sulfate Inorganic materials 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0803948.9A GB0803948D0 (en) | 2008-03-03 | 2008-03-03 | Combination therapy |
| GB0803948.9 | 2008-03-03 | ||
| PCT/EP2009/052394 WO2009109531A2 (en) | 2008-03-03 | 2009-02-27 | Combination therapy |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011513356A JP2011513356A (ja) | 2011-04-28 |
| JP2011513356A5 true JP2011513356A5 (enExample) | 2012-04-12 |
| JP5587215B2 JP5587215B2 (ja) | 2014-09-10 |
Family
ID=39315874
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010549109A Expired - Fee Related JP5587215B2 (ja) | 2008-03-03 | 2009-02-27 | 併用療法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10045984B2 (enExample) |
| EP (1) | EP2257292B1 (enExample) |
| JP (1) | JP5587215B2 (enExample) |
| CN (1) | CN101998856A (enExample) |
| CA (1) | CA2754281C (enExample) |
| CY (1) | CY1115555T1 (enExample) |
| DK (1) | DK2257292T3 (enExample) |
| ES (1) | ES2507570T3 (enExample) |
| GB (1) | GB0803948D0 (enExample) |
| PT (1) | PT2257292E (enExample) |
| WO (1) | WO2009109531A2 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2740657C1 (ru) * | 2020-05-15 | 2021-01-19 | Общество С Ограниченной Ответственностью "Промомед Рус" | Противовирусная композиция |
| NL2028566B1 (nl) * | 2021-06-29 | 2023-01-09 | Simons Care Innovation Group B V | Een zinkzout huidpleister en werkwijzen |
| JP7287730B2 (ja) * | 2021-10-12 | 2023-06-06 | ローバル株式会社 | ウイルスを不活化可能な高濃度亜鉛末塗料 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4125610A (en) * | 1977-07-27 | 1978-11-14 | Bristol-Myers Company | Antibacterial compositions |
| US5637311A (en) * | 1995-06-29 | 1997-06-10 | Procyte Corporation | Zinc(II) complexes and methods related thereto |
-
2008
- 2008-03-03 GB GBGB0803948.9A patent/GB0803948D0/en not_active Ceased
-
2009
- 2009-02-27 DK DK09716524.5T patent/DK2257292T3/da active
- 2009-02-27 US US12/920,345 patent/US10045984B2/en active Active
- 2009-02-27 CN CN2009801074137A patent/CN101998856A/zh active Pending
- 2009-02-27 JP JP2010549109A patent/JP5587215B2/ja not_active Expired - Fee Related
- 2009-02-27 PT PT97165245T patent/PT2257292E/pt unknown
- 2009-02-27 CA CA2754281A patent/CA2754281C/en active Active
- 2009-02-27 WO PCT/EP2009/052394 patent/WO2009109531A2/en not_active Ceased
- 2009-02-27 EP EP09716524.5A patent/EP2257292B1/en active Active
- 2009-02-27 ES ES09716524.5T patent/ES2507570T3/es active Active
-
2014
- 2014-09-11 CY CY20141100739T patent/CY1115555T1/el unknown