JP2011508779A5 - - Google Patents
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- Publication number
- JP2011508779A5 JP2011508779A5 JP2010541518A JP2010541518A JP2011508779A5 JP 2011508779 A5 JP2011508779 A5 JP 2011508779A5 JP 2010541518 A JP2010541518 A JP 2010541518A JP 2010541518 A JP2010541518 A JP 2010541518A JP 2011508779 A5 JP2011508779 A5 JP 2011508779A5
- Authority
- JP
- Japan
- Prior art keywords
- epimer
- compound
- halo
- alkyl
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1893808P | 2008-01-04 | 2008-01-04 | |
| US61/018,938 | 2008-01-04 | ||
| US8285008P | 2008-07-23 | 2008-07-23 | |
| US61/082,850 | 2008-07-23 | ||
| PCT/US2008/088529 WO2009088854A1 (en) | 2008-01-04 | 2008-12-30 | Epoxy-guaiane derivatives and treatment of cancer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011508779A JP2011508779A (ja) | 2011-03-17 |
| JP2011508779A5 true JP2011508779A5 (OSRAM) | 2012-02-16 |
| JP5547653B2 JP5547653B2 (ja) | 2014-07-16 |
Family
ID=40380295
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010541518A Active JP5547653B2 (ja) | 2008-01-04 | 2008-12-30 | エポキシ−グアイアン誘導体および癌の治療 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8410292B2 (OSRAM) |
| EP (1) | EP2235021B1 (OSRAM) |
| JP (1) | JP5547653B2 (OSRAM) |
| AU (1) | AU2008347299C1 (OSRAM) |
| CA (1) | CA2711434C (OSRAM) |
| DK (1) | DK2235021T3 (OSRAM) |
| ES (1) | ES2393877T3 (OSRAM) |
| WO (1) | WO2009088854A1 (OSRAM) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011120886A1 (en) | 2010-03-29 | 2011-10-06 | Institut Català D'investigació Química (Iciq) | A process for the preparation of (-)-englerin a, and analogues and intermediates thereof |
| EP2474550A1 (en) * | 2010-12-22 | 2012-07-11 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Derivatives of Englerin for the treatment of cancer |
| CA2860842A1 (en) | 2012-01-09 | 2013-07-18 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of treating or preventing insulin resistance and associated diseases and conditions |
| CN105025894B (zh) * | 2012-11-15 | 2017-06-09 | 美国卫生和人力服务部 | 治疗被hiv和htlv感染的患者的方法 |
| AU2015214189B2 (en) * | 2014-02-05 | 2018-12-13 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Aza-epoxy-guaiane derivatives and treatment of cancer |
| AU2016247920B2 (en) * | 2015-04-13 | 2020-12-24 | Fundacio Institut Catala D'investigacio Quimica | Epoxyazulene derivatives useful for treating cancer |
| CA3068980A1 (en) * | 2017-07-06 | 2019-01-10 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Englerin derivatives for treatment of cancer |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US5019369A (en) | 1984-10-22 | 1991-05-28 | Vestar, Inc. | Method of targeting tumors in humans |
| US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| CN1704417A (zh) | 2004-05-26 | 2005-12-07 | 杭州民生药业集团有限公司 | 新化合物莪术醇衍生物 |
-
2008
- 2008-12-30 AU AU2008347299A patent/AU2008347299C1/en active Active
- 2008-12-30 US US12/811,245 patent/US8410292B2/en active Active
- 2008-12-30 WO PCT/US2008/088529 patent/WO2009088854A1/en not_active Ceased
- 2008-12-30 EP EP08869946A patent/EP2235021B1/en active Active
- 2008-12-30 ES ES08869946T patent/ES2393877T3/es active Active
- 2008-12-30 DK DK08869946.7T patent/DK2235021T3/da active
- 2008-12-30 JP JP2010541518A patent/JP5547653B2/ja active Active
- 2008-12-30 CA CA2711434A patent/CA2711434C/en active Active
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