JP2011506399A5 - - Google Patents
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- Publication number
- JP2011506399A5 JP2011506399A5 JP2010537455A JP2010537455A JP2011506399A5 JP 2011506399 A5 JP2011506399 A5 JP 2011506399A5 JP 2010537455 A JP2010537455 A JP 2010537455A JP 2010537455 A JP2010537455 A JP 2010537455A JP 2011506399 A5 JP2011506399 A5 JP 2011506399A5
- Authority
- JP
- Japan
- Prior art keywords
- drug substance
- micronized
- hours
- temperature
- dry environment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims description 11
- VPNYRYCIDCJBOM-UHFFFAOYSA-M Glycopyrronium bromide Chemical group [Br-].C1[N+](C)(C)CCC1OC(=O)C(O)(C=1C=CC=CC=1)C1CCCC1 VPNYRYCIDCJBOM-UHFFFAOYSA-M 0.000 claims description 3
- 229940015042 glycopyrrolate Drugs 0.000 claims description 3
- 229940088679 drug related substance Drugs 0.000 claims 10
- 239000008186 active pharmaceutical agent Substances 0.000 claims 9
- 239000002904 solvent Substances 0.000 claims 2
- ANGKOCUUWGHLCE-HKUYNNGSSA-N [(3s)-1,1-dimethylpyrrolidin-1-ium-3-yl] (2r)-2-cyclopentyl-2-hydroxy-2-phenylacetate Chemical class C1[N+](C)(C)CC[C@@H]1OC(=O)[C@](O)(C=1C=CC=CC=1)C1CCCC1 ANGKOCUUWGHLCE-HKUYNNGSSA-N 0.000 claims 1
- 239000000853 adhesive Substances 0.000 claims 1
- 230000000181 anti-adherent effect Effects 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07123164 | 2007-12-13 | ||
| PCT/EP2008/067359 WO2009074662A2 (en) | 2007-12-13 | 2008-12-11 | Organic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011506399A JP2011506399A (ja) | 2011-03-03 |
| JP2011506399A5 true JP2011506399A5 (OSRAM) | 2012-01-19 |
Family
ID=39472711
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010537455A Pending JP2011506399A (ja) | 2007-12-13 | 2008-12-11 | 有機化合物 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20100247658A1 (OSRAM) |
| EP (1) | EP2234595B1 (OSRAM) |
| JP (1) | JP2011506399A (OSRAM) |
| KR (1) | KR20100099281A (OSRAM) |
| CN (1) | CN101896162B (OSRAM) |
| AU (1) | AU2008334543B2 (OSRAM) |
| BR (1) | BRPI0821186A2 (OSRAM) |
| CA (1) | CA2708083C (OSRAM) |
| ES (1) | ES2396471T3 (OSRAM) |
| PL (1) | PL2234595T3 (OSRAM) |
| PT (1) | PT2234595E (OSRAM) |
| RU (1) | RU2482838C2 (OSRAM) |
| WO (1) | WO2009074662A2 (OSRAM) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010253770B9 (en) * | 2009-05-29 | 2015-02-12 | Pearl Therapeutics, Inc. | Compositions for respiratory delivery of active agents and associated methods and systems |
| US9393202B2 (en) | 2013-04-26 | 2016-07-19 | Chiesi Farmaceutici S.P.A | Particle size reduction of an antimuscarinic compound |
| GB201307659D0 (en) | 2013-04-26 | 2013-06-12 | Korea Coast Guard Commissioner | Preparation of drug particles by micronisation |
| SG11201700536XA (en) | 2014-09-09 | 2017-02-27 | Vectura Ltd | Formulation comprising glycopyrrolate, method and apparatus |
| US9925168B2 (en) | 2016-01-22 | 2018-03-27 | Chiesi Farmaceutici S.P.A. | Preparation of micronized particles of an antimuscarinic compound by hydrodynamic cavitation |
| US10888500B2 (en) | 2016-07-29 | 2021-01-12 | Inke, S.A. | Particle size stabilization process |
| CN112137957B (zh) * | 2019-06-26 | 2022-07-29 | 长风药业股份有限公司 | 一种药用吸入气雾剂及其制备方法 |
| CN112972384B (zh) * | 2019-12-02 | 2022-03-18 | 长风药业股份有限公司 | 一种格隆溴铵和茚达特罗原料药微粉混合物的制备方法 |
| IT202300022716A1 (it) | 2023-10-30 | 2025-04-30 | Ind Chimica Srl | Processo di condizionamento di fluticasone furoato micronizzato |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9101090D0 (sv) * | 1991-04-11 | 1991-04-11 | Astra Ab | Process for conditioning of water-soluble substances |
| US5747002A (en) * | 1995-04-05 | 1998-05-05 | Genentech, Inc. | Preparation of sodium chloride aerosol formulations |
| US6613795B2 (en) * | 1996-11-11 | 2003-09-02 | Christian Noe | Enantiomerically pure basic arylcycloalkylhydroxycarboxylic esters, processes for their preparation and their use in medicaments |
| GB0008660D0 (en) * | 2000-04-07 | 2000-05-31 | Arakis Ltd | The treatment of respiratory diseases |
| PT2283817T (pt) * | 2000-11-30 | 2016-08-22 | Vectura Ltd | Método de fabrico de partículas para utilização numa composição farmacêutica |
| WO2005046655A1 (en) * | 2003-11-04 | 2005-05-26 | Shire Laboratories, Inc. | Sustained release of positively charged pharmacologically active molecules from a matrix containing polymers with polarized oxygen atoms |
| KR101179393B1 (ko) * | 2004-03-23 | 2012-09-07 | 노파르티스 아게 | 제약 조성물 |
| GB0409703D0 (en) * | 2004-04-30 | 2004-06-02 | Vectura Ltd | Pharmaceutical compositions |
| WO2006073154A1 (ja) * | 2005-01-07 | 2006-07-13 | Eisai R&D Management Co., Ltd. | 医薬組成物及びその製造方法 |
| GB0613161D0 (en) * | 2006-06-30 | 2006-08-09 | Novartis Ag | Organic Compounds |
-
2008
- 2008-12-11 EP EP08859423A patent/EP2234595B1/en active Active
- 2008-12-11 CN CN2008801205425A patent/CN101896162B/zh not_active Expired - Fee Related
- 2008-12-11 KR KR1020107015330A patent/KR20100099281A/ko not_active Ceased
- 2008-12-11 US US12/745,790 patent/US20100247658A1/en not_active Abandoned
- 2008-12-11 ES ES08859423T patent/ES2396471T3/es active Active
- 2008-12-11 RU RU2010128246/15A patent/RU2482838C2/ru not_active IP Right Cessation
- 2008-12-11 WO PCT/EP2008/067359 patent/WO2009074662A2/en not_active Ceased
- 2008-12-11 CA CA2708083A patent/CA2708083C/en not_active Expired - Fee Related
- 2008-12-11 AU AU2008334543A patent/AU2008334543B2/en not_active Ceased
- 2008-12-11 JP JP2010537455A patent/JP2011506399A/ja active Pending
- 2008-12-11 PL PL08859423T patent/PL2234595T3/pl unknown
- 2008-12-11 BR BRPI0821186-8A patent/BRPI0821186A2/pt not_active IP Right Cessation
- 2008-12-11 PT PT88594239T patent/PT2234595E/pt unknown
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