JP2011504474A5 - - Google Patents

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Publication number
JP2011504474A5
JP2011504474A5 JP2010534409A JP2010534409A JP2011504474A5 JP 2011504474 A5 JP2011504474 A5 JP 2011504474A5 JP 2010534409 A JP2010534409 A JP 2010534409A JP 2010534409 A JP2010534409 A JP 2010534409A JP 2011504474 A5 JP2011504474 A5 JP 2011504474A5
Authority
JP
Japan
Prior art keywords
use according
disease
medicament
inhibitor
alzheimer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010534409A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011504474A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2008/009880 external-priority patent/WO2009065596A2/en
Publication of JP2011504474A publication Critical patent/JP2011504474A/ja
Publication of JP2011504474A5 publication Critical patent/JP2011504474A5/ja
Pending legal-status Critical Current

Links

JP2010534409A 2007-11-22 2008-11-21 アルツハイマー氏病を治療するためのMnkインヒビターの使用 Pending JP2011504474A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07022695 2007-11-22
PCT/EP2008/009880 WO2009065596A2 (en) 2007-11-22 2008-11-21 Use of mnk inhibitors for the treatment of alzheimer's disease

Publications (2)

Publication Number Publication Date
JP2011504474A JP2011504474A (ja) 2011-02-10
JP2011504474A5 true JP2011504474A5 (enExample) 2011-12-22

Family

ID=40404966

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010534409A Pending JP2011504474A (ja) 2007-11-22 2008-11-21 アルツハイマー氏病を治療するためのMnkインヒビターの使用

Country Status (5)

Country Link
US (1) US20100247517A1 (enExample)
EP (1) EP2219649A2 (enExample)
JP (1) JP2011504474A (enExample)
CA (1) CA2706203A1 (enExample)
WO (1) WO2009065596A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5301986B2 (ja) * 2005-06-22 2013-09-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 医薬組成物用のチエノピリミジン類
JP5302883B2 (ja) * 2006-04-07 2013-10-02 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 医薬組成物用のmnk1/mnk2阻害活性を有するチエノピリミジン
EP1889847A1 (en) 2006-07-10 2008-02-20 DeveloGen Aktiengesellschaft Pyrrolopyrimidines for pharmaceutical compositions
US8877186B2 (en) * 2007-06-06 2014-11-04 Domantis Limited Polypeptides, antibody variable domains and antagonists
WO2010023181A1 (en) 2008-08-26 2010-03-04 Boehringer Ingelheim International Gmbh Thienopyrimidines for pharmaceutical compositions
MX2012009735A (es) * 2010-02-26 2012-09-12 Boehringer Ingelheim Int 4-[cicloalquiloxi (hetero) arilamino] tieno [2,3-d] pirimidinas que tienen actividad inhibitoria de mnk1/mnk2 para composiciones farmaceuticas.
UY33241A (es) 2010-02-26 2011-09-30 Boehringer Ingelheim Int ?Tienopirimidinas que contienen heterocicloalquilo para composiciones farmacéuticas?.
BR112012021453A2 (pt) * 2010-02-26 2017-02-21 Boehringer Ingelheim Int tienopirimidina, sua composição farmacêutica e seu uso
ES2649995T3 (es) 2011-07-18 2018-01-16 Merck Patent Gmbh Benzamidas
US9868744B2 (en) 2014-04-25 2018-01-16 Pfizer Inc. Heteroaromatic compounds and their use as dopamine D1 ligands
GB201520500D0 (en) * 2015-11-20 2016-01-06 Medical Res Council Technology Compounds
GB201520499D0 (en) * 2015-11-20 2016-01-06 Medical Res Council Technology Compounds
DK3582776T3 (da) 2017-02-14 2024-01-08 Effector Therapeutics Inc Piperidinsubstituerede mnk-hæmmere og dertil relaterede fremgangsmåder
KR20210102211A (ko) 2018-10-24 2021-08-19 이펙터 테라퓨틱스, 인크. Mnk 억제제의 결정질 형태

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW444018B (en) * 1992-12-17 2001-07-01 Pfizer Pyrazolopyrimidines
EP0729758A3 (en) * 1995-03-02 1997-10-29 Pfizer Pyrazolopyrimidines and pyrrolopyrimidines for the treatment of neuronal and other diseases
GB9906566D0 (en) * 1999-03-23 1999-05-19 Zeneca Ltd Chemical compounds
US7419978B2 (en) * 2003-10-22 2008-09-02 Bristol-Myers Squibb Company Phenyl-aniline substituted bicyclic compounds useful as kinase inhibitors
CA2551689A1 (en) * 2004-01-05 2005-07-28 Merz Pharma Gmbh & Co. Kgaa Memantine for the treatment of mild and mild-to-moderate alzheimer's disease
GB0412467D0 (en) * 2004-06-04 2004-07-07 Astrazeneca Ab Chemical compounds
EP1746099A1 (en) * 2004-12-23 2007-01-24 DeveloGen Aktiengesellschaft Mnk1 or Mnk2 inhibitors
JP5301986B2 (ja) * 2005-06-22 2013-09-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 医薬組成物用のチエノピリミジン類
WO2007059905A2 (en) * 2005-11-25 2007-05-31 Develogen Aktiengesellschaft Thienopyrimidines treating inflammatory diseases
RU2489155C2 (ru) * 2006-03-29 2013-08-10 Велакор Терапеутикс Пти Лтд Лечение нейродегенеративных заболеваний
FR2899107B1 (fr) * 2006-03-30 2008-06-13 Neurokin Entpr Unipersonnelle Utilisation de la (s)-roscovitine pour la fabrication d'un medicament
JP5302883B2 (ja) * 2006-04-07 2013-10-02 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 医薬組成物用のmnk1/mnk2阻害活性を有するチエノピリミジン
US20080107755A1 (en) * 2006-04-24 2008-05-08 Alltech, Inc. Methods and compositions for altering cell function
ATE456565T1 (de) * 2006-06-22 2010-02-15 Biovitrum Ab Publ Pyridin- und pyrazinderivate als mnk- kinaseinhibitoren

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