JP2011504361A - 肝細胞癌細胞に特異的なペプチドおよびその適用 - Google Patents

肝細胞癌細胞に特異的なペプチドおよびその適用 Download PDF

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JP2011504361A
JP2011504361A JP2010534284A JP2010534284A JP2011504361A JP 2011504361 A JP2011504361 A JP 2011504361A JP 2010534284 A JP2010534284 A JP 2010534284A JP 2010534284 A JP2010534284 A JP 2010534284A JP 2011504361 A JP2011504361 A JP 2011504361A
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seq
polypeptide
cancer
hcc
cells
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JP2011504361A5 (enExample
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ハン−チャン ウー，
チン−ターン リン，
アルバート ロー，
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Academia Sinica
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Academia Sinica
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2010534284A 2007-11-20 2008-11-19 肝細胞癌細胞に特異的なペプチドおよびその適用 Pending JP2011504361A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99648807P 2007-11-20 2007-11-20
PCT/US2008/084043 WO2009067520A2 (en) 2007-11-20 2008-11-19 Peptides specific for hepatocellular carcinoma cells and applications thereof

Publications (2)

Publication Number Publication Date
JP2011504361A true JP2011504361A (ja) 2011-02-10
JP2011504361A5 JP2011504361A5 (enExample) 2014-02-13

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JP2010534284A Pending JP2011504361A (ja) 2007-11-20 2008-11-19 肝細胞癌細胞に特異的なペプチドおよびその適用

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Country Link
US (1) US8541543B2 (enExample)
EP (1) EP2225262B1 (enExample)
JP (1) JP2011504361A (enExample)
CN (1) CN101918433B (enExample)
TW (1) TWI372866B (enExample)
WO (1) WO2009067520A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020089387A (ja) * 2012-12-17 2020-06-11 トリリアム・セラピューティクス・インコーポレイテッドＴｒｉｌｌｉｕｍ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． ＳＩＲＰアルファ−Ｆｃ融合体でのＣＤ４７＋疾患細胞の治療

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010138550A1 (en) * 2009-05-27 2010-12-02 Northeastern University Conjugated nanodelivery vehicles
CN102732522B (zh) * 2012-02-27 2014-04-09 南昌大学 一组肝癌血清核酸适配子
CN103804473B (zh) * 2014-01-23 2016-01-20 浙江大学 一种多肽及包含该多肽的核酸药物纳米粒
CN103804472B (zh) * 2014-01-23 2016-06-08 浙江大学 一种紫杉烷类药物前体
CN104667290A (zh) * 2014-10-25 2015-06-03 中国科学技术大学 一种靶向肽修饰的金纳米颗粒及其制备方法和其作为四价铂前体药物载体的应用
CN105039333B (zh) * 2015-08-21 2018-07-24 天津医科大学 肝癌靶向肽及其应用

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US4179337A (en) * 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
JPS6023084B2 (ja) * 1979-07-11 1985-06-05 味の素株式会社 代用血液
US4640835A (en) * 1981-10-30 1987-02-03 Nippon Chemiphar Company, Ltd. Plasminogen activator derivatives
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4496689A (en) * 1983-12-27 1985-01-29 Miles Laboratories, Inc. Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
EP0206448B1 (en) * 1985-06-19 1990-11-14 Ajinomoto Co., Inc. Hemoglobin combined with a poly(alkylene oxide)
US4791192A (en) * 1986-06-26 1988-12-13 Takeda Chemical Industries, Ltd. Chemically modified protein with polyethyleneglycol
US5080891A (en) * 1987-08-03 1992-01-14 Ddi Pharmaceuticals, Inc. Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols
US6552170B1 (en) 1990-04-06 2003-04-22 Amgen Inc. PEGylation reagents and compounds formed therewith
US6663885B1 (en) * 1993-03-15 2003-12-16 A. Natterman & Cie Gmbh Aqueous liposome system and a method for the preparation of such a liposome system
AU683957B2 (en) * 1993-11-05 1997-11-27 Amgen, Inc. Liposome preparation and material encapsulation method
US6051251A (en) * 1997-11-20 2000-04-18 Alza Corporation Liposome loading method using a boronic acid compound
KR100482920B1 (ko) * 2000-02-10 2005-04-14 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 간세포암을 치료하기 위한 조성물
US6974884B2 (en) * 2002-06-07 2005-12-13 Wisconsin Alumni Research Foundation Chemical synthesis of reagents for peptide coupling
TWI262192B (en) * 2003-07-01 2006-09-21 Univ Nat Taiwan Labeling peptide for nasopharyngeal carcinoma (NPC) cells
US7501486B2 (en) * 2004-09-07 2009-03-10 Burnham Institute For Medical Research Peptides that selectively home to heart vasculature and related conjugates and methods

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JPN6013046891; Ｂｉｎｇ　Ｄｕ，　Ｍｉｎ　Ｑｉａｎ，　Ｚｈｏｎｇｌｉａｎｇ　Ｚｈｏｕ，　Ｐｅｎｇ　Ｗａｎｇ，　Ｌｅｉ　Ｗａｎｇ，　Ｘｉａｏｐｉｎｇ　Ｚｈａｎｇ，　Ｍｉａｏ　Ｗｕ，　Ｐｉｎｇ　Ｚｈａｎｇ，　Ｂｉｎｇ　Ｍ: 'Ｉｎ　ｖｉｔｒｏ　ｐａｎｎｉｎｇ　ｏｆ　ａ　ｔａｒｇｅｔｉｎｇ　ｐｅｐｔｉｄｅ　ｔｏ　ｈｅｐａｔｏｃａｒｃｉｎｏｍａ　ｆｒｏｍ　ａ　ｐｈａｇｅ　ｄｉｓｐｌａｙ　ｐｅｐｔｉｄｅ　ｌｉｂｒａｒｙ' Ｂｉｏｃｈｅｍｉｃａｌ　ａｎｄ　Ｂｉｏｐｈｙｓｉｃａｌ　Ｒｅｓｅａｒｃｈ　Ｃｏｍｍｕｎｉｃａｔｉｏｎ Ｖｏｌ．&#x3000 *
JPN6013046893; Ｔｏｎｇ-Ｙｏｕｎｇ　Ｌｅｅ，　Ｈａｎ-Ｃｈｕｎｇ　Ｗｕ，　Ｙｕｎ-Ｌｏｎｇ　Ｔｓｅｎｇ，　Ｃｈｉｎ-Ｔａｒｎｇ　Ｌｉｎ: 'Ａ　ｎｏｖｅｌ　ｐｅｐｔｉｄｅ　ｓｐｅｃｉｆｉｃａｌｌｙ　ｂｉｎｄｉｎｇ　ｔｏ　ｎａｓｏｐｈａｒｙｎｇｅａｌ　ｃａｒｃｉｎｏｍａ　ｆｏｒ　ｔａｒｇｅｔｅｄ　ｄｒｕｇ　ｄｅｌｉｖｅｒｙ' Ｃａｎｃｅｒ　Ｒｅｓｅａｒｃｈ Ｖｏｌ．　６４，　Ｎｏ．　２１, 2004, ｐｐ．　８００２-８００８, Ａｍｅｒｉｃａｎ　Ａｓｓｏｃｉａｔｉｏｎ　ｆｏｒ　Ｃａｎｃｅｒ　Ｒｅｓｅａｒｃｈ *
JPN6013048669; Ｊｏｓｅｐｈ　Ｓａｍｂｒｏｏｋ，　Ｄａｖｉｄ　Ｗ．　Ｒｕｓｓｅｌｌ: Ｍｏｌｅｃｕｌａｒ　Ｃｌｏｎｉｎｇ，　Ａ　Ｌａｂｏｒａｔｏｒｙ　Ｍａｎｕａｌ，　３ｒｄ．　Ｅｄ Ｖｏｌ．２, 2001, ｐ．　１０．４７, Ｃｏｌｄ　Ｓｐｒｉｎｇ　Ｈａｒｂｏｒ　Ｌａｂｏｒａｔｏｒｙ *
JPN6014033056; Ｃｌｉｎ．　Ｅｘｐ．　Ｉｍｍｕｎｏｌ．，　１９９４，　Ｖｏｌ．　９７，　Ｎｏ．　２，　ｐｐ．　３２８-３３３ *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020089387A (ja) * 2012-12-17 2020-06-11 トリリアム・セラピューティクス・インコーポレイテッドＴｒｉｌｌｉｕｍ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． ＳＩＲＰアルファ−Ｆｃ融合体でのＣＤ４７＋疾患細胞の治療
JP7149450B2 (ja) 2012-12-17 2022-10-07 ピーエフ アージェンタム アイピー ホールディングズ エルエルシー ＳＩＲＰアルファ－Ｆｃ融合体でのＣＤ４７＋疾患細胞の治療

Also Published As

Publication number Publication date
TWI372866B (en) 2012-09-21
WO2009067520A3 (en) 2009-09-03
EP2225262B1 (en) 2016-04-27
US8541543B2 (en) 2013-09-24
CN101918433B (zh) 2013-06-26
US20090136418A1 (en) 2009-05-28
TW200935055A (en) 2009-08-16
EP2225262A2 (en) 2010-09-08
WO2009067520A2 (en) 2009-05-28
CN101918433A (zh) 2010-12-15

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