TWI372866B - Peptides specific for hepatocellular carcinoma cells and applications thereof - Google Patents

Peptides specific for hepatocellular carcinoma cells and applications thereof

Info

Publication number
TWI372866B
TWI372866B TW097144736A TW97144736A TWI372866B TW I372866 B TWI372866 B TW I372866B TW 097144736 A TW097144736 A TW 097144736A TW 97144736 A TW97144736 A TW 97144736A TW I372866 B TWI372866 B TW I372866B
Authority
TW
Taiwan
Prior art keywords
applications
hepatocellular carcinoma
carcinoma cells
peptides specific
peptides
Prior art date
Application number
TW097144736A
Other languages
English (en)
Other versions
TW200935055A (en
Inventor
Han Chung Wu
Chin Tarng Lin
Albert Lo
Original Assignee
Academia Sinica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Academia Sinica filed Critical Academia Sinica
Publication of TW200935055A publication Critical patent/TW200935055A/zh
Application granted granted Critical
Publication of TWI372866B publication Critical patent/TWI372866B/zh

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
TW097144736A 2007-11-20 2008-11-19 Peptides specific for hepatocellular carcinoma cells and applications thereof TWI372866B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US99648807P 2007-11-20 2007-11-20

Publications (2)

Publication Number Publication Date
TW200935055A TW200935055A (en) 2009-08-16
TWI372866B true TWI372866B (en) 2012-09-21

Family

ID=40329430

Family Applications (1)

Application Number Title Priority Date Filing Date
TW097144736A TWI372866B (en) 2007-11-20 2008-11-19 Peptides specific for hepatocellular carcinoma cells and applications thereof

Country Status (6)

Country Link
US (1) US8541543B2 (zh)
EP (1) EP2225262B1 (zh)
JP (1) JP2011504361A (zh)
CN (1) CN101918433B (zh)
TW (1) TWI372866B (zh)
WO (1) WO2009067520A2 (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120135064A1 (en) * 2009-05-27 2012-05-31 Northeastern University Conjugated nanodelivery vehicles
CN102732522B (zh) * 2012-02-27 2014-04-09 南昌大学 一组肝癌血清核酸适配子
DK3575326T3 (da) * 2012-12-17 2022-05-30 Pf Argentum Ip Holdings Llc Behandling af CD47+ sygdomsceller med SIRP ALFA-FC-fusioner
CN103804473B (zh) * 2014-01-23 2016-01-20 浙江大学 一种多肽及包含该多肽的核酸药物纳米粒
CN103804472B (zh) * 2014-01-23 2016-06-08 浙江大学 一种紫杉烷类药物前体
CN104667290A (zh) * 2014-10-25 2015-06-03 中国科学技术大学 一种靶向肽修饰的金纳米颗粒及其制备方法和其作为四价铂前体药物载体的应用
CN105039333B (zh) * 2015-08-21 2018-07-24 天津医科大学 肝癌靶向肽及其应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
JPS6023084B2 (ja) 1979-07-11 1985-06-05 味の素株式会社 代用血液
US4640835A (en) 1981-10-30 1987-02-03 Nippon Chemiphar Company, Ltd. Plasminogen activator derivatives
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4496689A (en) 1983-12-27 1985-01-29 Miles Laboratories, Inc. Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
DE3675588D1 (de) 1985-06-19 1990-12-20 Ajinomoto Kk Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist.
US4791192A (en) 1986-06-26 1988-12-13 Takeda Chemical Industries, Ltd. Chemically modified protein with polyethyleneglycol
US5080891A (en) 1987-08-03 1992-01-14 Ddi Pharmaceuticals, Inc. Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols
US6552170B1 (en) 1990-04-06 2003-04-22 Amgen Inc. PEGylation reagents and compounds formed therewith
US6663885B1 (en) 1993-03-15 2003-12-16 A. Natterman & Cie Gmbh Aqueous liposome system and a method for the preparation of such a liposome system
EP0678017B1 (en) 1993-11-05 1998-04-01 Amgen Inc. Liposome preparation and material encapsulation method
US6051251A (en) 1997-11-20 2000-04-18 Alza Corporation Liposome loading method using a boronic acid compound
EP1253930A4 (en) * 2000-02-10 2003-05-21 Univ California METHODS AND COMPOSITIONS FOR TREATING HEPATOCELLULAR CANCER
CA2489186C (en) 2002-06-07 2013-01-15 Wisconsin Alumni Research Foundation Chemical synthesis of reagents for peptide coupling
TWI262192B (en) * 2003-07-01 2006-09-21 Univ Nat Taiwan Labeling peptide for nasopharyngeal carcinoma (NPC) cells
US7501486B2 (en) * 2004-09-07 2009-03-10 Burnham Institute For Medical Research Peptides that selectively home to heart vasculature and related conjugates and methods
WO2006029459A1 (en) * 2004-09-13 2006-03-23 Evogenix, Inc Antibodies specific for hepatocellular carcinoma and other carcinomas and uses thereof

Also Published As

Publication number Publication date
EP2225262B1 (en) 2016-04-27
TW200935055A (en) 2009-08-16
CN101918433B (zh) 2013-06-26
JP2011504361A (ja) 2011-02-10
WO2009067520A3 (en) 2009-09-03
US8541543B2 (en) 2013-09-24
EP2225262A2 (en) 2010-09-08
US20090136418A1 (en) 2009-05-28
WO2009067520A2 (en) 2009-05-28
CN101918433A (zh) 2010-12-15

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