JP2011503199A5 - - Google Patents

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Publication number
JP2011503199A5
JP2011503199A5 JP2010534194A JP2010534194A JP2011503199A5 JP 2011503199 A5 JP2011503199 A5 JP 2011503199A5 JP 2010534194 A JP2010534194 A JP 2010534194A JP 2010534194 A JP2010534194 A JP 2010534194A JP 2011503199 A5 JP2011503199 A5 JP 2011503199A5
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JP
Japan
Prior art keywords
heterocyclic
condensed
nhr
benzene
cycloalkane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010534194A
Other languages
English (en)
Japanese (ja)
Other versions
JP5450434B2 (ja
JP2011503199A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/083478 external-priority patent/WO2009064938A1/en
Publication of JP2011503199A publication Critical patent/JP2011503199A/ja
Publication of JP2011503199A5 publication Critical patent/JP2011503199A5/ja
Application granted granted Critical
Publication of JP5450434B2 publication Critical patent/JP5450434B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2010534194A 2007-11-16 2008-11-14 関節炎の治療方法 Expired - Fee Related JP5450434B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98847907P 2007-11-16 2007-11-16
US60/988,479 2007-11-16
PCT/US2008/083478 WO2009064938A1 (en) 2007-11-16 2008-11-14 Method of treating arthritis

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013232754A Division JP5667684B2 (ja) 2007-11-16 2013-11-11 関節炎の治療方法

Publications (3)

Publication Number Publication Date
JP2011503199A JP2011503199A (ja) 2011-01-27
JP2011503199A5 true JP2011503199A5 (OSRAM) 2012-01-05
JP5450434B2 JP5450434B2 (ja) 2014-03-26

Family

ID=40291332

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2010534194A Expired - Fee Related JP5450434B2 (ja) 2007-11-16 2008-11-14 関節炎の治療方法
JP2013232754A Expired - Fee Related JP5667684B2 (ja) 2007-11-16 2013-11-11 関節炎の治療方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2013232754A Expired - Fee Related JP5667684B2 (ja) 2007-11-16 2013-11-11 関節炎の治療方法

Country Status (14)

Country Link
US (2) US20090176785A1 (OSRAM)
EP (1) EP2231159A1 (OSRAM)
JP (2) JP5450434B2 (OSRAM)
KR (1) KR101585848B1 (OSRAM)
CN (1) CN101969951B (OSRAM)
AU (1) AU2008322595B2 (OSRAM)
CA (1) CA2705294C (OSRAM)
DO (1) DOP2013000169A (OSRAM)
IL (2) IL205501A (OSRAM)
MX (1) MX2010005395A (OSRAM)
NZ (2) NZ585085A (OSRAM)
RU (2) RU2472509C2 (OSRAM)
WO (1) WO2009064938A1 (OSRAM)
ZA (1) ZA201003434B (OSRAM)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100160322A1 (en) 2008-12-04 2010-06-24 Abbott Laboratories Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
KR20130040834A (ko) 2010-03-25 2013-04-24 아비에 인코포레이티드 암 및 면역 및 자가면역 질환의 치료를 위한 아폽토시스―유도제
TWI520960B (zh) 2010-05-26 2016-02-11 艾伯維有限公司 用於治療癌症及免疫及自體免疫疾病之細胞凋亡誘導劑
UA113500C2 (xx) 2010-10-29 2017-02-10 Одержані екструзією розплаву тверді дисперсії, що містять індукуючий апоптоз засіб
EP2632436B1 (en) 2010-10-29 2018-08-29 Abbvie Inc. Solid dispersions containing an apoptosis-inducing agent
JP6141188B2 (ja) 2010-11-23 2017-06-07 アッヴィ・インコーポレイテッド アポトーシス誘導剤の塩および結晶の形態
NZ708508A (en) 2010-11-23 2016-06-24 Abbvie Bahamas Ltd Methods of treatment using selective bcl-2 inhibitors
US20140275082A1 (en) 2013-03-14 2014-09-18 Abbvie Inc. Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
CA3073446A1 (en) 2017-08-23 2019-02-28 Newave Pharmaceutical Inc. Bcl-2 inhibitors
WO2020041405A1 (en) 2018-08-22 2020-02-27 Newave Pharmaceutical Inc. Bcl-2 inhibitors
WO2020140005A2 (en) 2018-12-29 2020-07-02 Newave Pharmaceutical Inc. Bcl-2 inhibitors
WO2021066873A1 (en) 2019-10-03 2021-04-08 Newave Pharmaceutical Inc. Condensed heterocycles as bcl-2 inhibitors
JP2022553820A (ja) 2019-11-05 2022-12-26 アッヴィ・インコーポレイテッド 骨髄線維症及びmpn関連障害をナビトクラクスで処置する際に使用するための投与レジメン
WO2021133817A1 (en) 2019-12-27 2021-07-01 Guangzhou Lupeng Pharmaceutical Company Ltd. 1h-pyrrolo[2,3-b]pyridine derivatives as bcl-2 inhibitors for the treatment of neoplastic and autoimmune diseases
WO2021173523A1 (en) 2020-02-24 2021-09-02 Newave Pharmaceutical Inc. Hot melt extruded solid dispersions containing a bcl2 inhibitor
WO2022140224A1 (en) 2020-12-22 2022-06-30 Newave Pharmaceutical Inc. 1h-pyrrolo[2,3-b]pyridine derivatives as bcl-2 inhibitors for the treatment of neoplastic and autoimmune diseases

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9200275D0 (en) * 1992-01-08 1992-02-26 Roussel Lab Ltd Chemical compounds
JP3020612B2 (ja) * 1995-10-10 2000-03-15 ファイザー インク. ロイコトリエンアンタゴニストとしてのインドールカルバメート類
SK12842002A3 (sk) * 2000-03-21 2003-02-04 The Procter And Gamble Company Heterocyklický vedľajší reťazec obsahujúci N-substituované inhibítory metaloproteáz a farmaceutický prípravok s ich obsahom
WO2002032872A1 (fr) * 2000-10-20 2002-04-25 Eisai Co., Ltd. Composes a noyau aromatique azote
GB0217431D0 (en) * 2002-07-27 2002-09-04 Astrazeneca Ab Novel compounds
AU2004261610B2 (en) * 2003-07-28 2010-05-20 Janssen Pharmaceutica N.V. Benzimidazole, benzthiazole and benzoxazole derivatives and their use as LTA4H modulators
CA2536870C (en) * 2003-09-03 2009-10-27 Pfizer Inc. Phenyl or pyridyl amide compounds as prostaglandin e2 antagonists
WO2005049593A2 (en) * 2003-11-13 2005-06-02 Abbott Laboratories N-acylsulfonamide apoptosis promoters
ES2257929B1 (es) * 2004-07-16 2007-05-01 Laboratorios Del Dr. Esteve, S.A. Derivados de pirazolina, procedimiento para su obtencion y utilizacion de los mismos como agentes terapeuticos.
DK1888550T3 (da) * 2005-05-12 2014-09-29 Abbvie Bahamas Ltd Apoptosepromotorer
US20060276464A1 (en) * 2005-05-13 2006-12-07 Wyeth Diarylsulfone sulfonamides and use thereof
WO2008064116A2 (en) * 2006-11-16 2008-05-29 Abbott Laboratories Method of preventing or treating organ, hematopoietic stem cell or bone marrow transplant rejection

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