JP2011503129A5 - - Google Patents
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- Publication number
- JP2011503129A5 JP2011503129A5 JP2010533486A JP2010533486A JP2011503129A5 JP 2011503129 A5 JP2011503129 A5 JP 2011503129A5 JP 2010533486 A JP2010533486 A JP 2010533486A JP 2010533486 A JP2010533486 A JP 2010533486A JP 2011503129 A5 JP2011503129 A5 JP 2011503129A5
- Authority
- JP
- Japan
- Prior art keywords
- hydrogen atom
- alkyl group
- carbon atoms
- group
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 28
- 125000000217 alkyl group Chemical group 0.000 claims 27
- 125000004432 carbon atom Chemical group C* 0.000 claims 25
- 150000001875 compounds Chemical class 0.000 claims 22
- 239000000126 substance Substances 0.000 claims 11
- 238000000034 method Methods 0.000 claims 10
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 8
- 150000003839 salts Chemical class 0.000 claims 8
- 239000002537 cosmetic Substances 0.000 claims 6
- BQOIJSIMMIDHMO-FBPKJDBXSA-N 4-Hydroxytestosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1O BQOIJSIMMIDHMO-FBPKJDBXSA-N 0.000 claims 4
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 claims 4
- 238000010511 deprotection reaction Methods 0.000 claims 4
- 150000002148 esters Chemical class 0.000 claims 4
- 230000003779 hair growth Effects 0.000 claims 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 4
- 230000004060 metabolic process Effects 0.000 claims 4
- 210000004761 scalp Anatomy 0.000 claims 4
- 125000001424 substituent group Chemical group 0.000 claims 4
- KPPVNWGJXFMGAM-UUILKARUSA-N (e)-2-methyl-1-(6-methyl-3,4-dihydro-2h-quinolin-1-yl)but-2-en-1-one Chemical compound CC1=CC=C2N(C(=O)C(/C)=C/C)CCCC2=C1 KPPVNWGJXFMGAM-UUILKARUSA-N 0.000 claims 3
- 229940113178 5 Alpha reductase inhibitor Drugs 0.000 claims 3
- 239000002677 5-alpha reductase inhibitor Substances 0.000 claims 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 3
- 125000002252 acyl group Chemical group 0.000 claims 3
- 230000002280 anti-androgenic effect Effects 0.000 claims 3
- 239000000051 antiandrogen Substances 0.000 claims 3
- 229910052799 carbon Inorganic materials 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 208000002874 Acne Vulgaris Diseases 0.000 claims 2
- 102000014654 Aromatase Human genes 0.000 claims 2
- 108010078554 Aromatase Proteins 0.000 claims 2
- 208000035985 Body Odor Diseases 0.000 claims 2
- 208000035484 Cellulite Diseases 0.000 claims 2
- 108010066551 Cholestenone 5 alpha-Reductase Proteins 0.000 claims 2
- 102000008186 Collagen Human genes 0.000 claims 2
- 108010035532 Collagen Proteins 0.000 claims 2
- 206010049752 Peau d'orange Diseases 0.000 claims 2
- 206010040904 Skin odour abnormal Diseases 0.000 claims 2
- 206010000496 acne Diseases 0.000 claims 2
- 210000000577 adipose tissue Anatomy 0.000 claims 2
- 102000001307 androgen receptors Human genes 0.000 claims 2
- 108010080146 androgen receptors Proteins 0.000 claims 2
- 230000036232 cellulite Effects 0.000 claims 2
- 229920001436 collagen Polymers 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 230000002708 enhancing effect Effects 0.000 claims 2
- 206010033675 panniculitis Diseases 0.000 claims 2
- 230000000087 stabilizing effect Effects 0.000 claims 2
- 238000005728 strengthening Methods 0.000 claims 2
- 210000004304 subcutaneous tissue Anatomy 0.000 claims 2
- 210000001519 tissue Anatomy 0.000 claims 2
- 230000037303 wrinkles Effects 0.000 claims 2
- MEJYDZQQVZJMPP-ULAWRXDQSA-N (3s,3ar,6r,6ar)-3,6-dimethoxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan Chemical compound CO[C@H]1CO[C@@H]2[C@H](OC)CO[C@@H]21 MEJYDZQQVZJMPP-ULAWRXDQSA-N 0.000 claims 1
- 102000006771 Gonadotropins Human genes 0.000 claims 1
- 108010086677 Gonadotropins Proteins 0.000 claims 1
- 230000001195 anabolic effect Effects 0.000 claims 1
- 239000002622 gonadotropin Substances 0.000 claims 1
- 230000005764 inhibitory process Effects 0.000 claims 1
- 239000002207 metabolite Substances 0.000 claims 1
- 230000001590 oxidative effect Effects 0.000 claims 1
- 230000028327 secretion Effects 0.000 claims 1
- 239000012049 topical pharmaceutical composition Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US288207P | 2007-11-13 | 2007-11-13 | |
| EP07022015.7A EP2060261B1 (en) | 2007-11-13 | 2007-11-13 | C-19 steroids for cosmetic uses |
| PCT/EP2008/009540 WO2009062682A1 (en) | 2007-11-13 | 2008-11-12 | C-19 steroids for cosmetic and further uses |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011503129A JP2011503129A (ja) | 2011-01-27 |
| JP2011503129A5 true JP2011503129A5 (enExample) | 2012-01-05 |
Family
ID=39198683
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010533486A Pending JP2011503129A (ja) | 2007-11-13 | 2008-11-12 | 化粧用及び更なる使用のためのｃ−１９ステロイド |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8258123B2 (enExample) |
| EP (2) | EP2060261B1 (enExample) |
| JP (1) | JP2011503129A (enExample) |
| KR (2) | KR20100087005A (enExample) |
| CN (1) | CN101854908B (enExample) |
| AU (1) | AU2008323198B2 (enExample) |
| CA (1) | CA2705529C (enExample) |
| DK (1) | DK2060261T3 (enExample) |
| ES (1) | ES2574933T3 (enExample) |
| WO (1) | WO2009062682A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2060300B1 (en) * | 2007-11-13 | 2015-04-15 | Curadis GmbH | C-19 steroids for therapeutic uses |
| US11850451B2 (en) | 2011-01-31 | 2023-12-26 | Lucolas-M.D. Ltd. | Cosmetic compositions and methods for improving skin conditions |
| JP5872806B2 (ja) * | 2011-07-07 | 2016-03-01 | 花王株式会社 | Ｍｆａｐ−４産生促進剤 |
| EP2574329A1 (en) | 2011-09-28 | 2013-04-03 | ErlaCos GmbH | Deodorant comprising dimethyl isosorbide |
| JP5980512B2 (ja) * | 2012-01-30 | 2016-08-31 | 学校法人東日本学園 | 体臭抑制剤 |
| JP6145181B2 (ja) * | 2016-01-14 | 2017-06-07 | 花王株式会社 | Ｍｆａｐ−４産生促進剤 |
| MX383946B (es) * | 2016-08-03 | 2025-03-14 | Colgate Palmolive Co | Agente activo y método para reducir el mal olor. |
| FR3094229B1 (fr) | 2019-03-28 | 2021-11-12 | Roquette Freres | Composition topique pour le traitement des mauvaises odeurs corporelles, notamment l’halitose |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2763818A (en) * | 1954-10-14 | 1956-09-18 | Westinghouse Electric Corp | Lighting arrester |
| US2762818A (en) | 1955-05-26 | 1956-09-11 | Searle & Co | 4-hydroxytestosterone and esters thereof |
| ZA843232B (en) * | 1983-05-03 | 1984-12-24 | Bristol Myers Co | Antiperspirant stick with low staining potential |
| JPS62132810A (ja) * | 1985-12-05 | 1987-06-16 | Shiseido Co Ltd | 化粧料 |
| GB8721384D0 (en) * | 1987-09-11 | 1987-10-21 | Erba Farmitalia | 17-substituted andro-sta-1 4-dien-3-one derivatives |
| GB9021546D0 (en) | 1990-10-04 | 1990-11-21 | Beecham Group Plc | Novel composition |
| JPH06502161A (ja) | 1990-10-31 | 1994-03-10 | ビーチャム・グループ・パブリック・リミテッド・カンパニー | レチノイド浸透作用エンハンサーを含む局所用組成物 |
| US5486511A (en) | 1993-05-25 | 1996-01-23 | Merrell Dow Pharmaceuticals Inc. | 4-amino-17β-(cyclopropyloxy)androst-4-en-3-one, 4-amino-17β-(cyclopropylamino)androst-4-en-3-one and related compounds as C17-20 lyase and 5α-reductase |
| DE4405898A1 (de) | 1994-02-18 | 1995-08-24 | Schering Ag | Transdermale therapeutische Systeme enthaltend Sexualsteroide |
| DE69519582D1 (de) * | 1994-09-14 | 2001-01-11 | Univ Sheffield | Kontrolle des haarwuchses |
| US5824326A (en) * | 1997-06-27 | 1998-10-20 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Activity enhancement of ferulic acid with dimethyl isosorbride in cosmetic compositions |
| EP1429779A2 (en) | 2001-09-21 | 2004-06-23 | Merck & Co., Inc. | Androstanes as androgen receptor modulators |
| US6586417B1 (en) * | 2002-04-22 | 2003-07-01 | Nutrisport Pharmacal, Inc. | Ester and ether derivatives of 4-hydroxy 4-androstene-3,17-dione and a method for the regulation of athletic function in humans |
| US20030199487A1 (en) * | 2002-04-22 | 2003-10-23 | Mr. Vince Paternoster | Ester and ether derivatives of 4-hydroxytestosterone and a method for the regulation of athletic function in humans |
| US20030229063A1 (en) * | 2002-06-05 | 2003-12-11 | Llewellyn William Charles | Use of 4-hydroxytestosterone to lower estrogen levels in humans |
| US20060018937A1 (en) * | 2002-10-25 | 2006-01-26 | Foamix Ltd. | Steroid kit and foamable composition and uses thereof |
| EP1689864A2 (en) * | 2003-10-21 | 2006-08-16 | Dyad Pharmaceutical Corporation | Method and compositions for treating 5alpha-reductase type 1 and type 2 dependent conditions |
| EP1692317A4 (en) | 2003-12-12 | 2007-12-19 | Univ Rochester | Non-androgen dependent roles for androgen receptor and non-androgen related inhibitors of androgen receptor |
| WO2006084312A1 (en) * | 2005-02-09 | 2006-08-17 | Acrux Dds Pty Ltd | Method of promoting hair growth |
| JP4755845B2 (ja) * | 2005-04-28 | 2011-08-24 | 共栄化学工業株式会社 | テストステロン−５α−リダクターゼ阻害剤及びテストステロン−５α−リダクターゼ阻害剤を含有する化粧料。 |
| EP1854465A1 (en) * | 2006-05-12 | 2007-11-14 | Alexander Tobias Teichmann | Use of 4,17 beta-dihydroxyandrost-4-ene-3-one for treating cancers |
-
2007
- 2007-11-13 DK DK07022015.7T patent/DK2060261T3/en active
- 2007-11-13 ES ES07022015.7T patent/ES2574933T3/es active Active
- 2007-11-13 EP EP07022015.7A patent/EP2060261B1/en not_active Not-in-force
-
2008
- 2008-11-12 JP JP2010533486A patent/JP2011503129A/ja active Pending
- 2008-11-12 EP EP08850748A patent/EP2207523A1/en not_active Withdrawn
- 2008-11-12 CN CN2008801158388A patent/CN101854908B/zh not_active Expired - Fee Related
- 2008-11-12 US US12/734,621 patent/US8258123B2/en not_active Expired - Fee Related
- 2008-11-12 KR KR1020107010502A patent/KR20100087005A/ko not_active Ceased
- 2008-11-12 KR KR1020167007415A patent/KR101776544B1/ko not_active Expired - Fee Related
- 2008-11-12 WO PCT/EP2008/009540 patent/WO2009062682A1/en not_active Ceased
- 2008-11-12 AU AU2008323198A patent/AU2008323198B2/en not_active Ceased
- 2008-11-12 CA CA2705529A patent/CA2705529C/en not_active Expired - Fee Related
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