JP2011502964A - インバリアント鎖発現および/または異所性clip結合の競合的阻害剤 - Google Patents

インバリアント鎖発現および/または異所性clip結合の競合的阻害剤 Download PDF

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JP2011502964A
JP2011502964A JP2010531040A JP2010531040A JP2011502964A JP 2011502964 A JP2011502964 A JP 2011502964A JP 2010531040 A JP2010531040 A JP 2010531040A JP 2010531040 A JP2010531040 A JP 2010531040A JP 2011502964 A JP2011502964 A JP 2011502964A
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peptide
clip
binding
score
cells
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JP2011502964A5 (cg-RX-API-DMAC7.html
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ニューウェル,マーサ,カレン
ニューウェル,エヴァン
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University of Colorado System
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/15Natural-killer [NK] cells; Natural-killer T [NKT] cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/46Viral antigens
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P37/02Immunomodulators
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    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
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    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/30Detection of binding sites or motifs
    • GPHYSICS
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    • G16B35/00ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16CCOMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/60In silico combinatorial chemistry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Biophysics (AREA)
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  • Bioinformatics & Computational Biology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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JP2010531040A 2007-10-23 2008-10-23 インバリアント鎖発現および/または異所性clip結合の競合的阻害剤 Pending JP2011502964A (ja)

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Application Number Priority Date Filing Date Title
US15207P 2007-10-23 2007-10-23
US13596408P 2008-07-25 2008-07-25
US13715008P 2008-07-25 2008-07-25
PCT/US2008/012078 WO2009055005A2 (en) 2007-10-23 2008-10-23 Competitive inhibitors of invariant chain expression and/or ectopic clip binding

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JP2011502964A true JP2011502964A (ja) 2011-01-27
JP2011502964A5 JP2011502964A5 (cg-RX-API-DMAC7.html) 2012-12-20

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US (4) US8957031B2 (cg-RX-API-DMAC7.html)
EP (1) EP2215108A4 (cg-RX-API-DMAC7.html)
JP (1) JP2011502964A (cg-RX-API-DMAC7.html)
AU (1) AU2008317374B2 (cg-RX-API-DMAC7.html)
CA (1) CA2703585A1 (cg-RX-API-DMAC7.html)
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Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2676129A1 (en) * 2007-01-26 2008-08-07 The Regents Of The University Of Colorado Methods of modulating immune function
AU2008317374B2 (en) 2007-10-23 2015-03-19 The Regents Of The University Of Colorado Competitive inhibitors of invariant chain expression and/or ectopic clip binding
CA2737146A1 (en) * 2008-07-25 2010-01-28 The Regents Of The University Of Colorado Clip inhibitors and methods of modulating immune function
WO2010011315A2 (en) * 2008-07-25 2010-01-28 Viral Genetics, Inc. Proteins for use in diagnosing and treating infection and disease
US20100166782A1 (en) * 2008-07-25 2010-07-01 Martha Karen Newell Clip inhibitors and methods of modulating immune function
CA2860768A1 (en) 2011-01-05 2013-07-12 The Texas A&M University System Clip modulation for the treatment of mucosal diseases
WO2012138708A1 (en) * 2011-04-04 2012-10-11 The Texas A&M University System Mhc engagement and clip modulation for the treatment of disease
US9359404B2 (en) 2011-12-01 2016-06-07 Scott & White Healthcare Methods and products for treating preeclampsia and modulating blood pressure
WO2015035414A1 (en) * 2013-09-09 2015-03-12 The Texas A&M University System Treating neurological disorders
GB2536650A (en) 2015-03-24 2016-09-28 Augmedics Ltd Method and system for combining video-based and optic-based augmented reality in a near eye display
US20170177802A1 (en) * 2015-12-17 2017-06-22 Allergy Solutions, Inc. Allergy Service Management Portal
GB201522667D0 (en) 2015-12-22 2016-02-03 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against breast cancer and other cancers
SG10202111399YA (en) 2015-12-22 2021-11-29 Immatics Biotechnologies Gmbh Peptides and combination of peptides for use in immunotherapy against breast cancer and other cancers
WO2019055860A1 (en) * 2017-09-15 2019-03-21 The Texas A&M University System METHODS FOR IMPROVING IMMUNOTHERAPY IN THE TREATMENT OF CANCER
US12458411B2 (en) 2017-12-07 2025-11-04 Augmedics Ltd. Spinous process clamp
EP3517117A1 (en) * 2018-01-30 2019-07-31 Medizinische Universität Wien Medicament for prevention or treatment of rhinovirus infection
EP3787543A4 (en) 2018-05-02 2022-01-19 Augmedics Ltd. REGISTRATION OF A FIDUCIAL MARKER FOR AN AUGMENTED REALITY SYSTEM
US11766296B2 (en) 2018-11-26 2023-09-26 Augmedics Ltd. Tracking system for image-guided surgery
CN110033822B (zh) * 2019-03-29 2020-12-08 华中科技大学 蛋白质编码方法及蛋白质翻译后修饰位点预测方法及系统
TWI747121B (zh) * 2019-05-21 2021-11-21 大江生醫股份有限公司 茶樹葉的發酵物用於調控CCT基因、Pink1基因、PARP2基因、MITF基因、UNG基因、ERCC6基因、TERC基因、CD40基因、DYNLL2基因、GRK5基因、RELB基因、TNFSF14基因、IL4R基因與RELA基因的表現量及抗老化、美白、提升免疫力與降低脂肪累積之用途
CN110296833B (zh) * 2019-07-22 2020-08-18 齐鲁工业大学 一种面向液压缸综合测试台的软测量方法及系统
US12178666B2 (en) 2019-07-29 2024-12-31 Augmedics Ltd. Fiducial marker
US11980506B2 (en) 2019-07-29 2024-05-14 Augmedics Ltd. Fiducial marker
US11382712B2 (en) 2019-12-22 2022-07-12 Augmedics Ltd. Mirroring in image guided surgery
AU2021276693A1 (en) * 2020-05-22 2023-01-05 Carlos Alberto RIVEROS System, method and use of a certain medication for reducing viral replication in the airways mucosae
US11389252B2 (en) 2020-06-15 2022-07-19 Augmedics Ltd. Rotating marker for image guided surgery
US12239385B2 (en) 2020-09-09 2025-03-04 Augmedics Ltd. Universal tool adapter
US20220293228A1 (en) * 2021-03-09 2022-09-15 Glenn Loomis Identification of Allergens in Food Products
US11896445B2 (en) 2021-07-07 2024-02-13 Augmedics Ltd. Iliac pin and adapter
US12150821B2 (en) 2021-07-29 2024-11-26 Augmedics Ltd. Rotating marker and adapter for image-guided surgery
WO2023021450A1 (en) 2021-08-18 2023-02-23 Augmedics Ltd. Stereoscopic display and digital loupe for augmented-reality near-eye display
WO2023203521A1 (en) 2022-04-21 2023-10-26 Augmedics Ltd. Systems and methods for medical image visualization
JP2025531829A (ja) 2022-09-13 2025-09-25 オーグメディックス リミテッド 画像誘導医療介入のための拡張現実アイウェア

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011255A1 (en) * 1993-10-19 1995-04-27 Ajinomoto Co., Inc. Peptide capable of inducing immune response against hiv and aids preventive or remedy containing the peptide
WO1997025344A1 (en) * 1996-01-03 1997-07-17 The Australian National University Clip analogues and autoimmune disease

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415553A (en) 1973-08-06 1983-11-15 Dso "Pharmachim" Compositions, processes for their preparation and method for treatment of neoplasms
WO1985003003A1 (fr) * 1984-01-12 1985-07-18 Volker Rusch Substance biologiquement active avec des proprietes hormonales, son procede de fabrication et utilisation d'histones a des fins medicales
DE229046T1 (de) * 1985-03-30 1987-12-17 Marc Genf/Geneve Ballivet Verfahren zum erhalten von dns, rns, peptiden, polypeptiden oder proteinen durch dns-rekombinant-verfahren.
US7252829B1 (en) * 1998-06-17 2007-08-07 Idm Pharma, Inc. HLA binding peptides and their uses
EP0630257B1 (en) * 1992-03-13 2002-02-13 BEARDSLEY, Terry R. Thymus-derived, immune-enhancing agent for therapeutic use in immunocompromised hosts
US20050271676A1 (en) * 1993-03-05 2005-12-08 Epimmune Inc. Inducing cellular immune responses to human immunodeficiency virus-1 using peptide and nucleic acid compositions
BR9608837A (pt) 1995-05-01 1999-12-07 Tomson U S A Ltd "composição obtida de células para detectar uma infecção por vìrus da imunodeficiência humana, aparelho, kit e métodos para sua detecção, purificação da proteìna e sua obtenção e tratamento do ser humano"
US7625565B2 (en) * 1995-05-01 2009-12-01 Viral Genetics, Inc. Antiviral compositions comprising lysine-rich histone fractions prepared by pepsin treatment of thymic cell nuclei
US6245904B1 (en) * 1995-09-14 2001-06-12 The University Of Tubingen Recombinant polypeptide based on the primary sequence of the invariant chain with at least one primary sequence of a specific T-cell epitope or a protein derivative and nucleic acids coding for this recombinant polypeptide
US20060008448A1 (en) * 1996-06-11 2006-01-12 Minzhen Xu Inhibition of li expression in mammalian cells
CA2270223A1 (en) 1996-10-28 1998-05-07 Carson B. Burgstiner (Deceased) Methods and compositions for dietary supplementation
AU6336398A (en) * 1997-02-24 1998-09-09 Johns Hopkins University, The Immunomodulatory polypeptides derived from the invariant chain of mhc class ii
ZA988461B (en) * 1997-09-18 1999-03-30 Idec Pharma Corp Synergistic composition and methods for treating neoplastic or cancerous growths and for restoring or boosting hematopoiesis
US6165493A (en) * 1997-10-22 2000-12-26 New York Blood Center, Inc. "Methods and compositions for decreasing the frequency of HIV, herpesvirus and sexually transmitted bacterial infections"
US20020182222A1 (en) * 1998-07-10 2002-12-05 Groot Anne De HIV vaccine candidate peptides
US6734192B1 (en) * 1999-08-23 2004-05-11 Mp-1 Inc. Treatment of viral infections
US20020164685A1 (en) * 2000-01-31 2002-11-07 Rosen Craig A. Nucleic acids, proteins, and antibodies
WO2002061087A2 (en) * 2000-12-19 2002-08-08 Lifespan Biosciences, Inc. Antigenic peptides, such as for g protein-coupled receptors (gpcrs), antibodies thereto, and systems for identifying such antigenic peptides
CN1561389A (zh) 2001-07-25 2005-01-05 纽约大学 糖基神经酰胺作为用于抗传染病和癌症的疫苗的佐剂的用途
CN1458165A (zh) 2002-01-26 2003-11-26 北海新升技术开发有限责任公司 一种多肽类物质及其制备方法和用途
FR2836483B1 (fr) * 2002-02-22 2006-09-15 Innate Pharma Procedes de production de lymphocytes gamma delta t
ATE477276T1 (de) 2002-03-01 2010-08-15 Immunomedics Inc Internalisierung von anti cd74 monoklonalen antikörpern und deren verwendungen
AU2003302370A1 (en) 2002-09-23 2004-06-18 The Chancellor, Masters And Scholars Of The University Of Oxford Use of iminosugar derivatives to inhibit ion channel activity
CA2503748A1 (en) 2002-11-08 2004-05-27 Genentech, Inc. Compositions and methods for the treatment of natural killer cell related diseases
US6916627B2 (en) * 2002-11-27 2005-07-12 St. Jude Children's Research Hospital ATM kinase compositions and methods
WO2004110349A2 (en) * 2003-05-14 2004-12-23 Siga Technologies, Inc. Sars t cell epitopes and methods for identifying same
EP1638993A4 (en) 2003-06-10 2007-05-09 Univ Melbourne IMMUNOMODULATING COMPOSITIONS, APPLICATIONS THEREOF AND METHOD FOR THE PRODUCTION THEREOF
WO2005007673A2 (en) * 2003-07-03 2005-01-27 Rush University Medical Center Immunogenic peptides
US8101714B2 (en) 2004-02-18 2012-01-24 The University Of Georgia Research Foundation, Inc. Teleost derived antimicrobial polypeptides
WO2006114799A1 (en) * 2005-04-27 2006-11-02 Universita' Degli Studi Di Roma 'tor Vergata' Synthetic peptides for the diagnosis and therapy of berillium granulomatous disease
US20080094510A1 (en) * 2005-08-05 2008-04-24 Samsung Electronics Co., Ltd. Apparatus for providing multiple screens and method of dynamically configuring multiple screens
WO2007091240A2 (en) 2006-02-06 2007-08-16 Immune System Key Ltd. Treatment of immunological diseases
US20080095798A1 (en) * 2006-10-18 2008-04-24 Robert Humphreys Ii-key enhanced vaccine potency
US20090291884A1 (en) 2006-11-02 2009-11-26 Michael Agadjanyan Proteins for use in diagnosing and treating infection and disease
CA2676129A1 (en) 2007-01-26 2008-08-07 The Regents Of The University Of Colorado Methods of modulating immune function
AU2008317374B2 (en) 2007-10-23 2015-03-19 The Regents Of The University Of Colorado Competitive inhibitors of invariant chain expression and/or ectopic clip binding
US9073985B2 (en) * 2008-07-14 2015-07-07 The Regents Of The University Of Colorado, A Body Corporate Methods and products for treating proliferative diseases
US20100166782A1 (en) * 2008-07-25 2010-07-01 Martha Karen Newell Clip inhibitors and methods of modulating immune function
CA2737144A1 (en) * 2008-07-25 2010-01-28 The Regents Of The University Of Colorado Methods for treating viral disorders
WO2010011315A2 (en) * 2008-07-25 2010-01-28 Viral Genetics, Inc. Proteins for use in diagnosing and treating infection and disease
CA2860768A1 (en) * 2011-01-05 2013-07-12 The Texas A&M University System Clip modulation for the treatment of mucosal diseases
WO2012138708A1 (en) * 2011-04-04 2012-10-11 The Texas A&M University System Mhc engagement and clip modulation for the treatment of disease
US9359404B2 (en) * 2011-12-01 2016-06-07 Scott & White Healthcare Methods and products for treating preeclampsia and modulating blood pressure

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011255A1 (en) * 1993-10-19 1995-04-27 Ajinomoto Co., Inc. Peptide capable of inducing immune response against hiv and aids preventive or remedy containing the peptide
WO1997025344A1 (en) * 1996-01-03 1997-07-17 The Australian National University Clip analogues and autoimmune disease

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
JPN6013033779; Science,Vol.274(1996)p.618-620 *
JPN6013033780; J.Exp.Med.,Vol.184(1996)p.2019-2024 *
JPN6013033782; Database Protein [online], Accession No. Q0BZX0, <http://www.ncbi.nlm.nih.gov/protein/Q0BZX0> 28-NOV *
JPN6013033784; Bioinformatics,Vol.17,No.12(2001)p.1236-1237 *
JPN6013033786; Trends Immunol.,Vol.24,No.5(2003)p.264-268 *

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