JP2011500757A - Fc含有タンパク質の精製方法 - Google Patents

Fc含有タンパク質の精製方法 Download PDF

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Publication number
JP2011500757A
JP2011500757A JP2010530429A JP2010530429A JP2011500757A JP 2011500757 A JP2011500757 A JP 2011500757A JP 2010530429 A JP2010530429 A JP 2010530429A JP 2010530429 A JP2010530429 A JP 2010530429A JP 2011500757 A JP2011500757 A JP 2011500757A
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protein
resin
containing protein
free
blue
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JP2010530429A
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Japanese (ja)
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JP2011500757A5 (https=
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ウオン−デュバル,アレックス
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メルク セローノ ソシエテ アノニム
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Publication of JP2011500757A publication Critical patent/JP2011500757A/ja
Publication of JP2011500757A5 publication Critical patent/JP2011500757A5/ja
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/22Affinity chromatography or related techniques based upon selective absorption processes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
JP2010530429A 2007-10-22 2008-10-21 Fc含有タンパク質の精製方法 Withdrawn JP2011500757A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07118983 2007-10-22
US722307P 2007-12-11 2007-12-11
PCT/EP2008/064210 WO2009053360A1 (en) 2007-10-22 2008-10-21 Method for purifying an fc-containing protein

Publications (2)

Publication Number Publication Date
JP2011500757A true JP2011500757A (ja) 2011-01-06
JP2011500757A5 JP2011500757A5 (https=) 2011-12-08

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ID=38961834

Family Applications (1)

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JP2010530429A Withdrawn JP2011500757A (ja) 2007-10-22 2008-10-21 Fc含有タンパク質の精製方法

Country Status (7)

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US (1) US20100256337A1 (https=)
EP (1) EP2203465A1 (https=)
JP (1) JP2011500757A (https=)
AU (1) AU2008314689A1 (https=)
CA (1) CA2701221A1 (https=)
IL (1) IL204949A0 (https=)
WO (1) WO2009053360A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016502528A (ja) * 2012-11-27 2016-01-28 アルテオジェン インコーポレイテッド タンパク質とFcドメインを融合した融合タンパク質の安定化用組成物
JP2017521389A (ja) * 2014-06-13 2017-08-03 ルピン・リミテッド TNFR:Fc融合タンパク質の精製方法
US9821059B2 (en) 2014-10-17 2017-11-21 Alteogen Inc. Composition for stabilizing protein and pharmaceutical formulation comprising the same

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007022799A1 (en) * 2005-08-26 2007-03-01 Ares Trading S.A. Process for the preparation of glycosylated interferon beta
US20100249381A1 (en) * 2007-10-22 2010-09-30 David Delvaille Method for Purifying FC-Fusion Proteins
WO2010102114A1 (en) * 2009-03-05 2010-09-10 Biogen Idec Ma Inc. Purification of immunoglobulins
EP2918641A1 (en) * 2014-03-13 2015-09-16 Basf Se Method for purification of antibodies, antibody fragments or engineered variants thereof using specific anthraquinone dye-ligand structures
US20160347789A1 (en) * 2014-02-04 2016-12-01 Basf Se Method for purification of antibodies, antibody fragments or engineered variants thereof using specific anthraquinone dye-ligand structures
JP7749319B2 (ja) 2017-10-10 2025-10-06 アルパイン イミューン サイエンシズ インコーポレイテッド Ctla-4変異型免疫調節タンパク質およびそれらの使用
EP4146684A2 (en) 2020-05-08 2023-03-15 Alpine Immune Sciences, Inc. April and baff inhibitory immunomodulatory proteins with and without a t cell inhibitory protein and methods of use thereof
CN120904317A (zh) * 2025-09-28 2025-11-07 中国医学科学院输血研究所 一种两步亲和层析法制备犬用免疫球蛋白的方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4966843A (en) * 1982-11-01 1990-10-30 Cetus Corporation Expression of interferon genes in Chinese hamster ovary cells
JP3045539B2 (ja) * 1989-02-21 2000-05-29 ワシントン ユニバーシティ 改変型生殖ホルモン
US5338835A (en) * 1989-02-21 1994-08-16 Washington University CTP-extended form of FSH
ES2145744T5 (es) 1991-01-18 2008-02-01 Amgen Inc. Procedimientos para tratar las enfermedades inducidas por el factor de necrosis tumoral.
US5508261A (en) * 1991-06-18 1996-04-16 University Of Medicine & Dentistry Of New Jersey Analogs of glycoprotein hormones having altered receptor binding specificity and activity and methods for preparing and using same
SE9201073D0 (sv) * 1992-04-03 1992-04-03 Kabi Pharmacia Ab Protein formulation
US6162905A (en) * 1996-11-07 2000-12-19 Ibsa Institut Biochimique S.A. FSH and LH separation and purification process
US5883073A (en) * 1997-04-03 1999-03-16 Washington University Single-chain double-alpha peptide
US5990288A (en) * 1997-10-21 1999-11-23 Vitro Diagnostics, Inc. Method for purifying FSH
US7431921B2 (en) * 1999-08-27 2008-10-07 Maxygen Aps Interferon beta-like molecules
CZ303274B6 (cs) * 2000-02-22 2012-07-11 Merck Serono Sa Zpusob vycištení luteinizacního hormonu
EP2213743A1 (en) * 2000-04-12 2010-08-04 Human Genome Sciences, Inc. Albumin fusion proteins
US20030017550A1 (en) * 2001-01-22 2003-01-23 Pang Danny Zhong Der DNA sequences encoding fusion proteins comprising IFN-beta and TM-alpha1
US7226903B2 (en) * 2001-10-10 2007-06-05 Neose Technologies, Inc. Interferon beta: remodeling and glycoconjugation of interferon beta
AU2002364586A1 (en) * 2001-12-21 2003-07-30 Delta Biotechnology Limited Albumin fusion proteins
TWI353991B (en) * 2003-05-06 2011-12-11 Syntonix Pharmaceuticals Inc Immunoglobulin chimeric monomer-dimer hybrids
EP1697412B1 (en) * 2003-12-22 2009-10-21 Ares Trading S.A. Method for purifying fsh
DE602005009856D1 (de) * 2004-11-09 2008-10-30 Ares Trading Sa Verfahren zur reinigung von fsh
WO2007022799A1 (en) * 2005-08-26 2007-03-01 Ares Trading S.A. Process for the preparation of glycosylated interferon beta
EP1960419B1 (en) * 2005-12-09 2016-03-16 Ares Trading S.A. Method for purifying fsh or a fsh mutant
PL1981908T3 (pl) * 2006-01-17 2011-04-29 Merck Serono Sa Nowe D3N warianty glikolizacji FSH
US20100249381A1 (en) * 2007-10-22 2010-09-30 David Delvaille Method for Purifying FC-Fusion Proteins

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016502528A (ja) * 2012-11-27 2016-01-28 アルテオジェン インコーポレイテッド タンパク質とFcドメインを融合した融合タンパク質の安定化用組成物
US9474803B2 (en) 2012-11-27 2016-10-25 Alteogen Inc. Composition for stabilizing fusion protein in which protein and FC domain are fused
JP2017521389A (ja) * 2014-06-13 2017-08-03 ルピン・リミテッド TNFR:Fc融合タンパク質の精製方法
US9821059B2 (en) 2014-10-17 2017-11-21 Alteogen Inc. Composition for stabilizing protein and pharmaceutical formulation comprising the same

Also Published As

Publication number Publication date
WO2009053360A1 (en) 2009-04-30
EP2203465A1 (en) 2010-07-07
AU2008314689A1 (en) 2009-04-30
IL204949A0 (en) 2010-11-30
US20100256337A1 (en) 2010-10-07
CA2701221A1 (en) 2009-04-30

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