JP2011500688A - 制御された嵩密度を有する生分解性インプラント - Google Patents
制御された嵩密度を有する生分解性インプラント Download PDFInfo
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- JP2011500688A JP2011500688A JP2010529982A JP2010529982A JP2011500688A JP 2011500688 A JP2011500688 A JP 2011500688A JP 2010529982 A JP2010529982 A JP 2010529982A JP 2010529982 A JP2010529982 A JP 2010529982A JP 2011500688 A JP2011500688 A JP 2011500688A
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- YGSDEFSMJLZEOE-UHFFFAOYSA-M salicylate Chemical compound OC1=CC=CC=C1C([O-])=O YGSDEFSMJLZEOE-UHFFFAOYSA-M 0.000 description 1
- 229960002646 scopolamine Drugs 0.000 description 1
- STECJAGHUSJQJN-FWXGHANASA-N scopolamine Chemical compound C1([C@@H](CO)C(=O)O[C@H]2C[C@@H]3N([C@H](C2)[C@@H]2[C@H]3O2)C)=CC=CC=C1 STECJAGHUSJQJN-FWXGHANASA-N 0.000 description 1
- 229960002060 secobarbital Drugs 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 229940125723 sedative agent Drugs 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- JXKPEJDQGNYQSM-UHFFFAOYSA-M sodium propionate Chemical compound [Na+].CCC([O-])=O JXKPEJDQGNYQSM-UHFFFAOYSA-M 0.000 description 1
- 229960003212 sodium propionate Drugs 0.000 description 1
- 235000010334 sodium propionate Nutrition 0.000 description 1
- 239000004324 sodium propionate Substances 0.000 description 1
- 229960004025 sodium salicylate Drugs 0.000 description 1
- FKKAEMQFOIDZNY-WYMSNYCCSA-M sodium;4-[2-[(10r,13s,17r)-11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6h-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoate Chemical compound [Na+].O=C1C=C[C@]2(C)C3C(O)C[C@](C)([C@@](CC4)(O)C(=O)COC(=O)CCC([O-])=O)C4C3CCC2=C1 FKKAEMQFOIDZNY-WYMSNYCCSA-M 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 229960005322 streptomycin Drugs 0.000 description 1
- 229960002673 sulfacetamide Drugs 0.000 description 1
- SKIVFJLNDNKQPD-UHFFFAOYSA-N sulfacetamide Chemical compound CC(=O)NS(=O)(=O)C1=CC=C(N)C=C1 SKIVFJLNDNKQPD-UHFFFAOYSA-N 0.000 description 1
- 229960004306 sulfadiazine Drugs 0.000 description 1
- SEEPANYCNGTZFQ-UHFFFAOYSA-N sulfadiazine Chemical compound C1=CC(N)=CC=C1S(=O)(=O)NC1=NC=CC=N1 SEEPANYCNGTZFQ-UHFFFAOYSA-N 0.000 description 1
- 229960002135 sulfadimidine Drugs 0.000 description 1
- 229960000654 sulfafurazole Drugs 0.000 description 1
- 229960002597 sulfamerazine Drugs 0.000 description 1
- QPPBRPIAZZHUNT-UHFFFAOYSA-N sulfamerazine Chemical compound CC1=CC=NC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 QPPBRPIAZZHUNT-UHFFFAOYSA-N 0.000 description 1
- ASWVTGNCAZCNNR-UHFFFAOYSA-N sulfamethazine Chemical compound CC1=CC(C)=NC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 ASWVTGNCAZCNNR-UHFFFAOYSA-N 0.000 description 1
- 229960005158 sulfamethizole Drugs 0.000 description 1
- VACCAVUAMIDAGB-UHFFFAOYSA-N sulfamethizole Chemical compound S1C(C)=NN=C1NS(=O)(=O)C1=CC=C(N)C=C1 VACCAVUAMIDAGB-UHFFFAOYSA-N 0.000 description 1
- 229940124530 sulfonamide Drugs 0.000 description 1
- 150000003456 sulfonamides Chemical class 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000013269 sustained drug release Methods 0.000 description 1
- 229940127230 sympathomimetic drug Drugs 0.000 description 1
- IWVCMVBTMGNXQD-UHFFFAOYSA-N terramycin dehydrate Natural products C1=CC=C2C(O)(C)C3C(O)C4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-UHFFFAOYSA-N 0.000 description 1
- 229960002180 tetracycline Drugs 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 229920001187 thermosetting polymer Polymers 0.000 description 1
- 239000004634 thermosetting polymer Substances 0.000 description 1
- SRVJKTDHMYAMHA-WUXMJOGZSA-N thioacetazone Chemical compound CC(=O)NC1=CC=C(\C=N\NC(N)=S)C=C1 SRVJKTDHMYAMHA-WUXMJOGZSA-N 0.000 description 1
- 239000003204 tranquilizing agent Substances 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- 229960005294 triamcinolone Drugs 0.000 description 1
- GFNANZIMVAIWHM-OBYCQNJPSA-N triamcinolone Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@]([C@H](O)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 GFNANZIMVAIWHM-OBYCQNJPSA-N 0.000 description 1
- 229960003223 tripelennamine Drugs 0.000 description 1
- HWKQNAWCHQMZHK-UHFFFAOYSA-N trolnitrate Chemical compound [O-][N+](=O)OCCN(CCO[N+]([O-])=O)CCO[N+]([O-])=O HWKQNAWCHQMZHK-UHFFFAOYSA-N 0.000 description 1
- 229960002485 trolnitrate Drugs 0.000 description 1
- 229960004791 tropicamide Drugs 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 238000013022 venting Methods 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99960907P | 2007-10-18 | 2007-10-18 | |
| PCT/US2008/011967 WO2009051845A2 (en) | 2007-10-18 | 2008-10-20 | Biodegradable implants with controlled bulk density |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011500688A true JP2011500688A (ja) | 2011-01-06 |
| JP2011500688A5 JP2011500688A5 (cg-RX-API-DMAC7.html) | 2011-11-24 |
Family
ID=40185976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010529982A Pending JP2011500688A (ja) | 2007-10-18 | 2008-10-20 | 制御された嵩密度を有する生分解性インプラント |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20090123518A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2197418A2 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2011500688A (cg-RX-API-DMAC7.html) |
| CN (2) | CN104288844A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2009051845A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102017106216A1 (de) * | 2017-03-22 | 2018-09-27 | Amw Gmbh | Extrudierte Depotform zur anhaltenden Wirkstofffreisetzung |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04217914A (ja) * | 1990-05-10 | 1992-08-07 | Nkk Corp | 徐放性製剤の製造方法 |
| JP2006514672A (ja) * | 2003-03-04 | 2006-05-11 | ノストラム・ファーマスーティカルズ・インコーポレイテッド | 疎水性物質を徐放剤として含有する制御性放出製剤 |
| JP2006522782A (ja) * | 2003-03-01 | 2006-10-05 | アーダナ バイオサイエンス リミテッド | 植込剤の新規製造方法 |
| JP2007517042A (ja) * | 2003-12-30 | 2007-06-28 | デュレクト コーポレーション | 活性物質、好ましくはｇｎｒｈの制御放出のための、好ましくはｐｅｇおよびｐｌｇの混合物を含有するポリマーインプラント |
| JP2007211049A (ja) * | 2006-02-07 | 2007-08-23 | Lion Corp | 酸触媒を含まないハイパーブランチポリマーの製造方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060234918A1 (en) * | 2001-12-19 | 2006-10-19 | Voyager Pharmaceutical Corporation | Methods for treating and preventing cancers that express the hypothalamic-pituitary-gonadal axis of hormones and receptors |
| US7074426B2 (en) * | 2002-03-27 | 2006-07-11 | Frank Kochinke | Methods and drug delivery systems for the treatment of orofacial diseases |
| US20050048099A1 (en) * | 2003-01-09 | 2005-03-03 | Allergan, Inc. | Ocular implant made by a double extrusion process |
| US20040247671A1 (en) * | 2003-04-25 | 2004-12-09 | Prescott James H. | Solid drug formulation and device for storage and controlled delivery thereof |
| CN100534527C (zh) * | 2003-12-30 | 2009-09-02 | 杜雷科特公司 | 用于控制释放优选为GnRH的活性剂的优选含有PEG和PLG的混合物的聚合植入物 |
| JP4661504B2 (ja) * | 2005-09-29 | 2011-03-30 | 富士フイルム株式会社 | 熱可塑性樹脂フィルム及びその製造方法 |
| EP1837014A1 (en) * | 2006-03-21 | 2007-09-26 | Hexal Ag | Subcutaneous implants containing a degradation-resistant polylactide polymer and a LH-RH analogue |
| ITMI20061538A1 (it) * | 2006-08-02 | 2008-02-03 | Mediolanum Pharmaceuticals Ltd | Impianti sottocutanei in grado di rilasciare il principio attivo per un periodo prolungato di tempo |
-
2008
- 2008-10-20 US US12/288,537 patent/US20090123518A1/en not_active Abandoned
- 2008-10-20 JP JP2010529982A patent/JP2011500688A/ja active Pending
- 2008-10-20 WO PCT/US2008/011967 patent/WO2009051845A2/en not_active Ceased
- 2008-10-20 EP EP08840757A patent/EP2197418A2/en not_active Withdrawn
- 2008-10-20 CN CN201410194344.0A patent/CN104288844A/zh active Pending
- 2008-10-20 CN CN200880112115.2A patent/CN101873849B/zh not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04217914A (ja) * | 1990-05-10 | 1992-08-07 | Nkk Corp | 徐放性製剤の製造方法 |
| JP2006522782A (ja) * | 2003-03-01 | 2006-10-05 | アーダナ バイオサイエンス リミテッド | 植込剤の新規製造方法 |
| JP2006514672A (ja) * | 2003-03-04 | 2006-05-11 | ノストラム・ファーマスーティカルズ・インコーポレイテッド | 疎水性物質を徐放剤として含有する制御性放出製剤 |
| JP2007517042A (ja) * | 2003-12-30 | 2007-06-28 | デュレクト コーポレーション | 活性物質、好ましくはｇｎｒｈの制御放出のための、好ましくはｐｅｇおよびｐｌｇの混合物を含有するポリマーインプラント |
| JP2007211049A (ja) * | 2006-02-07 | 2007-08-23 | Lion Corp | 酸触媒を含まないハイパーブランチポリマーの製造方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101873849B (zh) | 2014-06-18 |
| WO2009051845A2 (en) | 2009-04-23 |
| WO2009051845A3 (en) | 2010-01-28 |
| US20090123518A1 (en) | 2009-05-14 |
| CN101873849A (zh) | 2010-10-27 |
| EP2197418A2 (en) | 2010-06-23 |
| CN104288844A (zh) | 2015-01-21 |
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