JP2011500688A5 - - Google Patents
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- Publication number
- JP2011500688A5 JP2011500688A5 JP2010529982A JP2010529982A JP2011500688A5 JP 2011500688 A5 JP2011500688 A5 JP 2011500688A5 JP 2010529982 A JP2010529982 A JP 2010529982A JP 2010529982 A JP2010529982 A JP 2010529982A JP 2011500688 A5 JP2011500688 A5 JP 2011500688A5
- Authority
- JP
- Japan
- Prior art keywords
- implant
- permeable
- poly
- solid
- drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007943 implant Substances 0.000 claims 28
- 239000007787 solid Substances 0.000 claims 19
- 239000003814 drug Substances 0.000 claims 12
- 238000000034 method Methods 0.000 claims 12
- 229940079593 drug Drugs 0.000 claims 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 9
- 239000013583 drug formulation Substances 0.000 claims 8
- 229920000642 polymer Polymers 0.000 claims 6
- 230000003204 osmotic effect Effects 0.000 claims 4
- 229920000747 poly(lactic acid) Polymers 0.000 claims 4
- 229920001606 poly(lactic acid-co-glycolic acid) Polymers 0.000 claims 4
- RKDVKSZUMVYZHH-UHFFFAOYSA-N 1,4-dioxane-2,5-dione Chemical compound O=C1COC(=O)CO1 RKDVKSZUMVYZHH-UHFFFAOYSA-N 0.000 claims 2
- 108010000817 Leuprolide Proteins 0.000 claims 2
- 239000004952 Polyamide Substances 0.000 claims 2
- 229920002732 Polyanhydride Polymers 0.000 claims 2
- 239000002202 Polyethylene glycol Substances 0.000 claims 2
- 229920000954 Polyglycolide Polymers 0.000 claims 2
- 229920001577 copolymer Polymers 0.000 claims 2
- 230000001186 cumulative effect Effects 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- GFIJNRVAKGFPGQ-LIJARHBVSA-N leuprolide Chemical compound CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H]1NC(=O)CC1)CC1=CC=C(O)C=C1 GFIJNRVAKGFPGQ-LIJARHBVSA-N 0.000 claims 2
- 229960004338 leuprorelin Drugs 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 150000002905 orthoesters Chemical class 0.000 claims 2
- 229940065514 poly(lactide) Drugs 0.000 claims 2
- 229920002647 polyamide Polymers 0.000 claims 2
- 229920001610 polycaprolactone Polymers 0.000 claims 2
- 239000004632 polycaprolactone Substances 0.000 claims 2
- 229920000515 polycarbonate Polymers 0.000 claims 2
- 239000004417 polycarbonate Substances 0.000 claims 2
- 229920006149 polyester-amide block copolymer Polymers 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- -1 polyphosphadine Polymers 0.000 claims 2
- 230000003750 conditioning effect Effects 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 238000001125 extrusion Methods 0.000 claims 1
- 230000035699 permeability Effects 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99960907P | 2007-10-18 | 2007-10-18 | |
| PCT/US2008/011967 WO2009051845A2 (en) | 2007-10-18 | 2008-10-20 | Biodegradable implants with controlled bulk density |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011500688A JP2011500688A (ja) | 2011-01-06 |
| JP2011500688A5 true JP2011500688A5 (cg-RX-API-DMAC7.html) | 2011-11-24 |
Family
ID=40185976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010529982A Pending JP2011500688A (ja) | 2007-10-18 | 2008-10-20 | 制御された嵩密度を有する生分解性インプラント |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20090123518A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2197418A2 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2011500688A (cg-RX-API-DMAC7.html) |
| CN (2) | CN104288844A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2009051845A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102017106216A1 (de) * | 2017-03-22 | 2018-09-27 | Amw Gmbh | Extrudierte Depotform zur anhaltenden Wirkstofffreisetzung |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04217914A (ja) * | 1990-05-10 | 1992-08-07 | Nkk Corp | 徐放性製剤の製造方法 |
| US20060234918A1 (en) * | 2001-12-19 | 2006-10-19 | Voyager Pharmaceutical Corporation | Methods for treating and preventing cancers that express the hypothalamic-pituitary-gonadal axis of hormones and receptors |
| US7074426B2 (en) * | 2002-03-27 | 2006-07-11 | Frank Kochinke | Methods and drug delivery systems for the treatment of orofacial diseases |
| US20050048099A1 (en) * | 2003-01-09 | 2005-03-03 | Allergan, Inc. | Ocular implant made by a double extrusion process |
| GB0304726D0 (en) * | 2003-03-01 | 2003-04-02 | Ardana Bioscience Ltd | New Process |
| JP2006514672A (ja) * | 2003-03-04 | 2006-05-11 | ノストラム・ファーマスーティカルズ・インコーポレイテッド | 疎水性物質を徐放剤として含有する制御性放出製剤 |
| US20040247671A1 (en) * | 2003-04-25 | 2004-12-09 | Prescott James H. | Solid drug formulation and device for storage and controlled delivery thereof |
| AU2004313245B2 (en) * | 2003-12-30 | 2011-04-14 | Durect Corporation | Polymeric implants, preferably containing a mixture of PEG and PLG, for controlled release of active agents, preferably a GNRH |
| CN100534527C (zh) * | 2003-12-30 | 2009-09-02 | 杜雷科特公司 | 用于控制释放优选为GnRH的活性剂的优选含有PEG和PLG的混合物的聚合植入物 |
| JP4661504B2 (ja) * | 2005-09-29 | 2011-03-30 | 富士フイルム株式会社 | 熱可塑性樹脂フィルム及びその製造方法 |
| JP2007211049A (ja) * | 2006-02-07 | 2007-08-23 | Lion Corp | 酸触媒を含まないハイパーブランチポリマーの製造方法 |
| EP1837014A1 (en) * | 2006-03-21 | 2007-09-26 | Hexal Ag | Subcutaneous implants containing a degradation-resistant polylactide polymer and a LH-RH analogue |
| ITMI20061538A1 (it) * | 2006-08-02 | 2008-02-03 | Mediolanum Pharmaceuticals Ltd | Impianti sottocutanei in grado di rilasciare il principio attivo per un periodo prolungato di tempo |
-
2008
- 2008-10-20 US US12/288,537 patent/US20090123518A1/en not_active Abandoned
- 2008-10-20 JP JP2010529982A patent/JP2011500688A/ja active Pending
- 2008-10-20 WO PCT/US2008/011967 patent/WO2009051845A2/en not_active Ceased
- 2008-10-20 EP EP08840757A patent/EP2197418A2/en not_active Withdrawn
- 2008-10-20 CN CN201410194344.0A patent/CN104288844A/zh active Pending
- 2008-10-20 CN CN200880112115.2A patent/CN101873849B/zh not_active Expired - Fee Related
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