JP2011500599A5 - - Google Patents

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Publication number
JP2011500599A5
JP2011500599A5 JP2010529092A JP2010529092A JP2011500599A5 JP 2011500599 A5 JP2011500599 A5 JP 2011500599A5 JP 2010529092 A JP2010529092 A JP 2010529092A JP 2010529092 A JP2010529092 A JP 2010529092A JP 2011500599 A5 JP2011500599 A5 JP 2011500599A5
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JP
Japan
Prior art keywords
ring
pain
compound
optionally substituted
aliphatic
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JP2010529092A
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English (en)
Japanese (ja)
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JP2011500599A (ja
JP5436434B2 (ja
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Priority claimed from PCT/US2008/079544 external-priority patent/WO2009049181A1/en
Publication of JP2011500599A publication Critical patent/JP2011500599A/ja
Publication of JP2011500599A5 publication Critical patent/JP2011500599A5/ja
Application granted granted Critical
Publication of JP5436434B2 publication Critical patent/JP5436434B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2010529092A 2007-10-11 2008-10-10 電位開口型ナトリウムチャネルの阻害剤として有用なアミド Expired - Fee Related JP5436434B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97929207P 2007-10-11 2007-10-11
US60/979,292 2007-10-11
PCT/US2008/079544 WO2009049181A1 (en) 2007-10-11 2008-10-10 Amides useful as inhibitors of voltage-gated sodium channels

Publications (3)

Publication Number Publication Date
JP2011500599A JP2011500599A (ja) 2011-01-06
JP2011500599A5 true JP2011500599A5 (cg-RX-API-DMAC7.html) 2012-11-22
JP5436434B2 JP5436434B2 (ja) 2014-03-05

Family

ID=40373424

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010529092A Expired - Fee Related JP5436434B2 (ja) 2007-10-11 2008-10-10 電位開口型ナトリウムチャネルの阻害剤として有用なアミド

Country Status (13)

Country Link
US (2) US8389734B2 (cg-RX-API-DMAC7.html)
EP (1) EP2212292B1 (cg-RX-API-DMAC7.html)
JP (1) JP5436434B2 (cg-RX-API-DMAC7.html)
KR (1) KR20100066583A (cg-RX-API-DMAC7.html)
CN (1) CN101855210A (cg-RX-API-DMAC7.html)
AU (1) AU2008310661A1 (cg-RX-API-DMAC7.html)
CA (1) CA2701766A1 (cg-RX-API-DMAC7.html)
IL (1) IL204977A0 (cg-RX-API-DMAC7.html)
MX (1) MX2010003864A (cg-RX-API-DMAC7.html)
NZ (1) NZ584474A (cg-RX-API-DMAC7.html)
RU (1) RU2010118481A (cg-RX-API-DMAC7.html)
WO (1) WO2009049181A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201002471B (cg-RX-API-DMAC7.html)

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WO2018009618A1 (en) * 2016-07-07 2018-01-11 Dow Agrosciences Llc Processes for the preparation of 4-alkoxy-3-(acyl or alkyl)oxypicolinamides
JP7104070B2 (ja) 2017-05-16 2022-07-20 バーテックス ファーマシューティカルズ インコーポレイテッド ナトリウムチャネルの調節因子としての重水素化ピリドンアミドおよびそのプロドラッグ
ES3008911T3 (en) 2017-07-11 2025-03-25 Vertex Pharma Carboxamides as modulators of sodium channels
US20190343817A1 (en) 2018-02-12 2019-11-14 Vertex Pharmaceuticals Incorporated Method of treating pain
CN112689629B (zh) 2018-07-09 2024-04-23 利伯研究所公司 用于抑制Nav1.8的哒嗪化合物
CA3105657A1 (en) * 2018-07-09 2020-01-16 Lieber Institute, Inc. Pyridine carboxamide compounds for inhibiting nav1.8
CN110885328B (zh) * 2018-09-10 2022-08-12 成都康弘药业集团股份有限公司 作为钠通道阻滞剂的磺酰胺类化合物及其用途
EP3873468A4 (en) * 2018-11-02 2022-10-26 Merck Sharp & Dohme LLC 2-AMINO-N-PHENYL-NICOTINAMIDES AS NAV1.8 INHIBITORS
JOP20210097A1 (ar) 2018-11-02 2023-01-30 Merck Sharp & Dohme مركبات 2-أمينو-n-أريل غير متجانس-نيكوتيناميد كمثبطات nav1.8
US12441703B2 (en) 2019-01-10 2025-10-14 Vertex Pharmaceuticals Incorporated Carboxamides as modulators of sodium channels
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