JP2011500597A5 - - Google Patents
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- Publication number
- JP2011500597A5 JP2011500597A5 JP2010529089A JP2010529089A JP2011500597A5 JP 2011500597 A5 JP2011500597 A5 JP 2011500597A5 JP 2010529089 A JP2010529089 A JP 2010529089A JP 2010529089 A JP2010529089 A JP 2010529089A JP 2011500597 A5 JP2011500597 A5 JP 2011500597A5
- Authority
- JP
- Japan
- Prior art keywords
- topical composition
- skin
- patient
- pharmaceutically acceptable
- active agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims description 31
- 208000017520 skin disease Diseases 0.000 claims description 6
- 201000004624 Dermatitis Diseases 0.000 claims description 5
- 208000010668 atopic eczema Diseases 0.000 claims description 4
- 208000000069 hyperpigmentation Diseases 0.000 claims description 4
- 230000003810 hyperpigmentation Effects 0.000 claims description 4
- 206010040882 skin lesion Diseases 0.000 claims description 4
- 231100000444 skin lesion Toxicity 0.000 claims description 4
- 206010039793 Seborrhoeic dermatitis Diseases 0.000 claims description 3
- 208000008742 seborrheic dermatitis Diseases 0.000 claims description 3
- 208000002874 Acne Vulgaris Diseases 0.000 claims description 2
- 206010012438 Dermatitis atopic Diseases 0.000 claims description 2
- 206010015150 Erythema Diseases 0.000 claims description 2
- 201000004681 Psoriasis Diseases 0.000 claims description 2
- 241001303601 Rosacea Species 0.000 claims description 2
- 206010000496 acne Diseases 0.000 claims description 2
- 208000009621 actinic keratosis Diseases 0.000 claims description 2
- 230000032683 aging Effects 0.000 claims description 2
- 208000004631 alopecia areata Diseases 0.000 claims description 2
- 201000008937 atopic dermatitis Diseases 0.000 claims description 2
- 231100000321 erythema Toxicity 0.000 claims description 2
- 208000001875 irritant dermatitis Diseases 0.000 claims description 2
- 208000006934 radiodermatitis Diseases 0.000 claims description 2
- 201000004700 rosacea Diseases 0.000 claims description 2
- 230000000699 topical effect Effects 0.000 claims 31
- CBOQJANXLMLOSS-UHFFFAOYSA-N ethyl vanillin Chemical compound CCOC1=CC(C=O)=CC=C1O CBOQJANXLMLOSS-UHFFFAOYSA-N 0.000 claims 10
- 239000000546 pharmaceutical excipient Substances 0.000 claims 9
- 210000003491 skin Anatomy 0.000 claims 8
- 239000013543 active substance Substances 0.000 claims 7
- 239000003937 drug carrier Substances 0.000 claims 7
- 229940073505 ethyl vanillin Drugs 0.000 claims 5
- 229920001296 polysiloxane Polymers 0.000 claims 4
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims 4
- 102000005741 Metalloproteases Human genes 0.000 claims 3
- 108010006035 Metalloproteases Proteins 0.000 claims 3
- 230000005540 biological transmission Effects 0.000 claims 3
- 210000004207 dermis Anatomy 0.000 claims 3
- 210000002615 epidermis Anatomy 0.000 claims 3
- 239000003961 penetration enhancing agent Substances 0.000 claims 3
- 230000000770 proinflammatory effect Effects 0.000 claims 3
- 102100040206 Hyaluronan synthase 2 Human genes 0.000 claims 2
- 101710197056 Hyaluronan synthase 2 Proteins 0.000 claims 2
- 239000011159 matrix material Substances 0.000 claims 2
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims 2
- 229960004889 salicylic acid Drugs 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 206010012442 Dermatitis contact Diseases 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- BJIOGJUNALELMI-ONEGZZNKSA-N Isoeugenol Natural products COC1=CC(\C=C\C)=CC=C1O BJIOGJUNALELMI-ONEGZZNKSA-N 0.000 claims 1
- 102100030412 Matrix metalloproteinase-9 Human genes 0.000 claims 1
- 108010015302 Matrix metalloproteinase-9 Proteins 0.000 claims 1
- 208000002029 allergic contact dermatitis Diseases 0.000 claims 1
- BJIOGJUNALELMI-ARJAWSKDSA-N cis-isoeugenol Chemical compound COC1=CC(\C=C/C)=CC=C1O BJIOGJUNALELMI-ARJAWSKDSA-N 0.000 claims 1
- 238000004090 dissolution Methods 0.000 claims 1
- 239000003995 emulsifying agent Substances 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 208000027866 inflammatory disease Diseases 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 230000005764 inhibitory process Effects 0.000 claims 1
- IUSBVFZKQJGVEP-SNAWJCMRSA-N isoeugenol acetate Chemical compound COC1=CC(\C=C\C)=CC=C1OC(C)=O IUSBVFZKQJGVEP-SNAWJCMRSA-N 0.000 claims 1
- 230000003902 lesion Effects 0.000 claims 1
- 231100000241 scar Toxicity 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 230000000638 stimulation Effects 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- BJIOGJUNALELMI-UHFFFAOYSA-N trans-isoeugenol Natural products COC1=CC(C=CC)=CC=C1O BJIOGJUNALELMI-UHFFFAOYSA-N 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 230000000172 allergic effect Effects 0.000 description 2
- 210000002950 fibroblast Anatomy 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 102000016942 Elastin Human genes 0.000 description 1
- 108010014258 Elastin Proteins 0.000 description 1
- 101710128038 Hyaluronan synthase Proteins 0.000 description 1
- 206010042496 Sunburn Diseases 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 229920002549 elastin Polymers 0.000 description 1
- 210000002865 immune cell Anatomy 0.000 description 1
- 210000002510 keratinocyte Anatomy 0.000 description 1
- 210000002752 melanocyte Anatomy 0.000 description 1
- 210000001616 monocyte Anatomy 0.000 description 1
- 230000037390 scarring Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99834507P | 2007-10-10 | 2007-10-10 | |
| US60/998,345 | 2007-10-10 | ||
| US12647808P | 2008-05-05 | 2008-05-05 | |
| US61/126,478 | 2008-05-05 | ||
| PCT/US2008/079534 WO2009049172A1 (en) | 2007-10-10 | 2008-10-10 | Methods and compositions for treating dermatological diseases and conditions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011500597A JP2011500597A (ja) | 2011-01-06 |
| JP2011500597A5 true JP2011500597A5 (enExample) | 2014-01-23 |
| JP5570992B2 JP5570992B2 (ja) | 2014-08-13 |
Family
ID=40549597
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010529089A Expired - Fee Related JP5570992B2 (ja) | 2007-10-10 | 2008-10-10 | 皮膚病又は皮膚病変の治療方法及び組成物 |
Country Status (5)
| Country | Link |
|---|---|
| EP (2) | EP2244690B1 (enExample) |
| JP (1) | JP5570992B2 (enExample) |
| CA (3) | CA3006143C (enExample) |
| HK (1) | HK1245679A1 (enExample) |
| WO (1) | WO2009049172A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9616006B2 (en) | 2007-10-10 | 2017-04-11 | DermaMedics, LLC | Methods and compositions for treating dermatological diseases and conditions |
| JP5596444B2 (ja) * | 2010-07-07 | 2014-09-24 | 花王株式会社 | 抗炎症剤の評価又は選択方法 |
| FR2973230B1 (fr) * | 2011-04-01 | 2013-11-01 | Oreal | Utilisation de gingerone ou de ses derives pour diminuer ou retarder les signes du vieillissement de la peau |
| FI3777876T3 (fi) | 2011-10-28 | 2023-10-18 | Neostrata Company Inc | N-asyylidipeptidijohdannaisia ja niiden käyttöjä |
| DE102013204088A1 (de) * | 2013-03-11 | 2014-09-11 | Beiersdorf Ag | Wirkstoffkombinationen aus Alkylamidothiazolen und einen oder mehreren kosmetisch oder dermatologisch relevanten Duftstoffen |
| KR101914844B1 (ko) * | 2013-10-24 | 2018-11-02 | 더 프록터 앤드 갬블 캄파니 | 피부 미백 화장 조성물 및 방법 |
| US20190298688A1 (en) * | 2016-11-21 | 2019-10-03 | Vivier Canada Inc. | Putrescine slow-release topical formulations |
| JP7047997B2 (ja) * | 2017-12-21 | 2022-04-05 | ポーラ化成工業株式会社 | 組成物 |
| JP7356228B2 (ja) * | 2018-01-31 | 2023-10-04 | 株式会社コーセー | 組成物 |
| WO2020180311A1 (en) * | 2019-03-06 | 2020-09-10 | Zen-Bio, Inc. | Plant-based exosome compositions and use thereof for rejuvenating skin |
| WO2020205539A1 (en) * | 2019-03-29 | 2020-10-08 | Vizuri Health Sciences Consumer Healthcare, Inc. | Compositions and methods for the prevention and treatment of radiation dermatitis, eczema, burns, wounds and certain cancers |
| WO2022122122A1 (en) * | 2020-12-08 | 2022-06-16 | Symrise Ag | Medicament for fighting inflammatory conditions of human skin (i) |
| WO2022128054A1 (en) * | 2020-12-14 | 2022-06-23 | Symrise Ag | Medicament for fighting inflammatory conditions of human skin (iv) |
| WO2022128051A1 (en) * | 2020-12-14 | 2022-06-23 | Symrise Ag | Medicament for fighting inflammatory conditions of human skin (ii) |
| CN114588139A (zh) * | 2022-03-16 | 2022-06-07 | 中国农业大学 | 乙基香兰素在制备抗皮肤光损伤产品中的用途 |
| CN118078795A (zh) * | 2024-02-28 | 2024-05-28 | 首都医科大学附属北京友谊医院 | 乙酸异丁香酚酯在制备预防和/或治疗炎症性肠病的药物中的用途 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3909816A (en) | 1974-04-29 | 1975-09-30 | Lloyd L Teeters | Flame and carbon monoxide sensor and alarm circuit |
| US4405616A (en) | 1975-06-19 | 1983-09-20 | Nelson Research & Development Company | Penetration enhancers for transdermal drug delivery of systemic agents |
| US4983396A (en) | 1985-12-06 | 1991-01-08 | Key Pharmaceuticals, Inc. | Percutaneous penetration enhancer of oleic acid and 2-ethyl-1,3-hexanediol |
| US4886783A (en) | 1986-01-31 | 1989-12-12 | Nelson Research & Development Co. | Penetration enhancers for transdermal delivery of systemic agents |
| US4801586A (en) | 1986-04-23 | 1989-01-31 | Nelson Research & Development Co. | Penetration enhancers for transdermal delivery of systemic agents |
| US5118845A (en) | 1986-09-29 | 1992-06-02 | Whitby Research, Inc. | Penetration enhancer for transdermal delivery of systemic agents |
| US5196410A (en) | 1986-10-31 | 1993-03-23 | Pfizer Inc. | Transdermal flux enhancing compositions |
| US4861764A (en) | 1986-11-17 | 1989-08-29 | Macro Chem. Corp. | Percutaneous absorption enhancers, compositions containing same and method of use |
| US8283135B2 (en) * | 2000-06-30 | 2012-10-09 | The Procter & Gamble Company | Oral care compositions containing combinations of anti-bacterial and host-response modulating agents |
| FR2829696B1 (fr) * | 2001-09-17 | 2004-02-27 | Oreal | Utilisation de l'acide pantetheine sulfonique et/ou de ses sels en tant qu'agent anti-radicalaire |
| IL161545A0 (en) * | 2001-11-16 | 2004-09-27 | Cutanix Corp | Pharmaceutical and cosmetic compositions containing oxy group-bearing aromatic aldehydes |
| DE20221578U1 (de) * | 2001-12-07 | 2006-06-08 | Hoenzelaer, Norbert | Vorrichtung und Pflaster zur kontrollierten Freisetzung von Vanillin |
| SE0201880D0 (sv) * | 2002-06-19 | 2002-06-19 | Milenca Gardovic | Komposition för att behandla hudåkommor och för att förbättra hårtillväxt |
| US7776915B2 (en) * | 2005-03-24 | 2010-08-17 | Tracie Martyn International, Llc | Topical formulations and methods of use |
| US20060229347A1 (en) * | 2005-03-30 | 2006-10-12 | Astion Development A/S | Treatment of eczemas |
| US20070207220A1 (en) * | 2006-03-01 | 2007-09-06 | Kathryn Luedtke | Method for improving sleep behaviors |
-
2008
- 2008-10-10 JP JP2010529089A patent/JP5570992B2/ja not_active Expired - Fee Related
- 2008-10-10 EP EP08837020.0A patent/EP2244690B1/en not_active Not-in-force
- 2008-10-10 CA CA3006143A patent/CA3006143C/en active Active
- 2008-10-10 CA CA2866527A patent/CA2866527C/en active Active
- 2008-10-10 EP EP17174953.4A patent/EP3238696A1/en not_active Withdrawn
- 2008-10-10 WO PCT/US2008/079534 patent/WO2009049172A1/en not_active Ceased
- 2008-10-10 CA CA2740200A patent/CA2740200C/en active Active
-
2011
- 2011-04-29 HK HK18105517.3A patent/HK1245679A1/en unknown
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