JP2011500049A5 - - Google Patents
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- Publication number
- JP2011500049A5 JP2011500049A5 JP2010529468A JP2010529468A JP2011500049A5 JP 2011500049 A5 JP2011500049 A5 JP 2011500049A5 JP 2010529468 A JP2010529468 A JP 2010529468A JP 2010529468 A JP2010529468 A JP 2010529468A JP 2011500049 A5 JP2011500049 A5 JP 2011500049A5
- Authority
- JP
- Japan
- Prior art keywords
- modified
- reovirus
- cell
- virus
- genome
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 241000702263 Reovirus sp. Species 0.000 claims 24
- 238000000034 method Methods 0.000 claims 23
- 210000004027 cell Anatomy 0.000 claims 17
- 241000700605 Viruses Species 0.000 claims 13
- 108090000565 Capsid Proteins Proteins 0.000 claims 7
- 102100023321 Ceruloplasmin Human genes 0.000 claims 7
- 241000702247 Reoviridae Species 0.000 claims 5
- 125000000487 histidyl group Chemical group [H]N([H])C(C(=O)O*)C([H])([H])C1=C([H])N([H])C([H])=N1 0.000 claims 5
- 238000004519 manufacturing process Methods 0.000 claims 5
- 150000007523 nucleic acids Chemical class 0.000 claims 5
- 101001028244 Onchocerca volvulus Fatty-acid and retinol-binding protein 1 Proteins 0.000 claims 4
- 210000004899 c-terminal region Anatomy 0.000 claims 3
- 230000004048 modification Effects 0.000 claims 3
- 238000012986 modification Methods 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 2
- 102000040650 (ribonucleotides)n+m Human genes 0.000 claims 2
- 241001480512 Mammalian orthoreovirus 3 Species 0.000 claims 2
- 102000009572 RNA Polymerase II Human genes 0.000 claims 2
- 108010009460 RNA Polymerase II Proteins 0.000 claims 2
- 230000001419 dependent effect Effects 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 238000013518 transcription Methods 0.000 claims 2
- 230000035897 transcription Effects 0.000 claims 2
- 210000000605 viral structure Anatomy 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 241000702259 Orbivirus Species 0.000 claims 1
- 241000702244 Orthoreovirus Species 0.000 claims 1
- 241000702670 Rotavirus Species 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 230000006907 apoptotic process Effects 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 230000030833 cell death Effects 0.000 claims 1
- 230000024245 cell differentiation Effects 0.000 claims 1
- 230000004663 cell proliferation Effects 0.000 claims 1
- 230000033077 cellular process Effects 0.000 claims 1
- 239000002299 complementary DNA Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 230000006806 disease prevention Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 230000000644 propagated effect Effects 0.000 claims 1
- 230000001902 propagating effect Effects 0.000 claims 1
- 241000894007 species Species 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0720624.6A GB0720624D0 (en) | 2007-10-20 | 2007-10-20 | Viral Modification |
| PCT/IB2008/002758 WO2009050573A2 (en) | 2007-10-20 | 2008-10-16 | Viral modification of reoviridae |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011500049A JP2011500049A (ja) | 2011-01-06 |
| JP2011500049A5 true JP2011500049A5 (enExample) | 2011-12-01 |
Family
ID=38814243
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010529468A Abandoned JP2011500049A (ja) | 2007-10-20 | 2008-10-16 | ウイルス修飾 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20100278863A1 (enExample) |
| EP (1) | EP2201027A2 (enExample) |
| JP (1) | JP2011500049A (enExample) |
| CN (1) | CN101918434A (enExample) |
| AU (1) | AU2008313411A1 (enExample) |
| CA (1) | CA2703034A1 (enExample) |
| GB (1) | GB0720624D0 (enExample) |
| WO (1) | WO2009050573A2 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9249195B2 (en) * | 2010-04-07 | 2016-02-02 | Vanderbilt University | Reovirus vaccines and methods of use therefor |
| US20220111034A1 (en) * | 2019-01-18 | 2022-04-14 | Université Catholique de Louvain | Virus compositions |
| KR20210098202A (ko) * | 2020-01-31 | 2021-08-10 | 바이로큐어 주식회사 | 레오바이러스를 유효성분으로 포함하는 대장염의 예방 또는 치료용 조성물 |
| JP2024512575A (ja) * | 2021-03-23 | 2024-03-19 | バイロキュア インコーポレイテッド | 弱毒化されたレオウイルスベースのワクチン組成物及びその用途 |
| CN118291538A (zh) * | 2024-04-01 | 2024-07-05 | 华南农业大学 | 宿主细胞的ocln基因在调控呼肠孤病毒复制中的应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA200800246B (en) * | 2005-08-31 | 2009-08-26 | Oncolytics Biotech Inc | Treatment with an oncolytic virus and an immunostimulant for in vivo enhancement of immune system recognition of neoplasms |
| JP2007215466A (ja) * | 2006-02-16 | 2007-08-30 | Fujita Gakuen | レオウイルス科ウイルス由来の組換えウイルスを調製する方法、及び組換えロタウイルス調製用のｄｎａコンストラクト |
| AR066649A1 (es) * | 2007-05-21 | 2009-09-02 | Oncolytics Biotech Inc | Reovirus mutantes y metodos de elaboracion y uso de los mismos |
-
2007
- 2007-10-20 GB GBGB0720624.6A patent/GB0720624D0/en not_active Ceased
-
2008
- 2008-10-16 JP JP2010529468A patent/JP2011500049A/ja not_active Abandoned
- 2008-10-16 CN CN2008801202605A patent/CN101918434A/zh active Pending
- 2008-10-16 CA CA2703034A patent/CA2703034A1/en not_active Abandoned
- 2008-10-16 AU AU2008313411A patent/AU2008313411A1/en not_active Abandoned
- 2008-10-16 US US12/738,814 patent/US20100278863A1/en not_active Abandoned
- 2008-10-16 EP EP08839407A patent/EP2201027A2/en not_active Withdrawn
- 2008-10-16 WO PCT/IB2008/002758 patent/WO2009050573A2/en not_active Ceased
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