JP2011250994A - Medicine discharge implement and double-chamber container using medicine discharge implement - Google Patents

Medicine discharge implement and double-chamber container using medicine discharge implement Download PDF

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JP2011250994A
JP2011250994A JP2010126790A JP2010126790A JP2011250994A JP 2011250994 A JP2011250994 A JP 2011250994A JP 2010126790 A JP2010126790 A JP 2010126790A JP 2010126790 A JP2010126790 A JP 2010126790A JP 2011250994 A JP2011250994 A JP 2011250994A
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container
flow path
medicine
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container body
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JP5594687B2 (en
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Toshiharu Yokoyama
敏晴 横山
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Otsuka Pharmaceutical Co Ltd
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Abstract

PROBLEM TO BE SOLVED: To provide a double-chamber container which can prevent medicines before mixing from being discharged and can be easily manufactured, and to provide a medicine discharge implement to be attached to the double-chamber container.SOLUTION: The medicine discharge device is attached to a container body with storage chambers for storing medicine and partition seal parts to unsealably partition between storage chambers and can discharge the medicine from the container body. The medicine discharge device comprises: a discharge device body with first and second flow passages communicating the container body side with a side exposed outside from the container body; a first seal member which blocks an opening to the container body side in the first flow passage and can open the opening by external force; a second seal member which can be inserted through the opening exposed outside in the second flow passage and blocks the second flow passage; and a plug member which blocks the opening to the side exposed outside in the first and the second flow passages.

Description

本発明は、同時に配合すると経時変化を起こすような不安定な各種薬剤(液剤、粉末若しくは固形剤)を個別に収納する複数の収納室を備えた複室容器、及び、当該複室容器に取り付けられる薬剤排出具に関する。   The present invention relates to a multi-chamber container having a plurality of storage chambers for individually storing various unstable drugs (solutions, powders or solid agents) that change with time when mixed simultaneously, and attached to the multi-chamber container. It is related with the medicine discharge device.

静脈注射により患者に投与される薬剤や、眼灌流液、腹膜透析液などの薬剤の中には、予め配合すると望ましくない経時変化を起こすような不安定な薬剤がある。例えば、アミノ酸輸液とブドウ糖輸液とを配合して保存しておくと、いわゆるメイラード反応によって混合液が褐変する。また、脂肪乳剤と電解質溶液とを配合して保存しておくと、脂肪分が凝集を生じ、リン酸含有液とカルシウム含有液とを配合しておくと、リン酸カルシウムの沈殿を生じ、望ましくない変化を起こす。   Among drugs such as ocular perfusate and peritoneal dialysis fluid that are administered to a patient by intravenous injection, there are unstable drugs that cause an undesirable change over time when pre-mixed. For example, when an amino acid infusion solution and a glucose infusion solution are blended and stored, the mixed solution browns by a so-called Maillard reaction. Also, if fat emulsion and electrolyte solution are blended and stored, fat will aggregate, and if phosphoric acid-containing liquid and calcium-containing liquid are blended, calcium phosphate will precipitate and undesirable changes will occur. Wake up.

このような薬剤に対しては、次のような複室容器が用いられることが多い。この複室容器は、薬剤を収納する2つの収納室を備えたプラスチックフィルム製の容器本体と、この容器本体から薬剤を排出する薬剤排出具とを備えている。2つの収納室は、容器本体の内壁面同士を熱融着した仕切り用封止部によって仕切られている。使用に際しては、いずれかの収納室の中央付近を押圧し、収納室内の圧力を高めて仕切り用封止部を開封する。これによって両収納室が連通し、2つの薬剤が混合される。その後、薬剤排出具を刺入等によって開封し、混合後の薬剤を患者に投与する。   For such drugs, the following multi-chamber container is often used. The multi-chamber container includes a plastic film container main body having two storage chambers for storing medicines, and a medicine discharging tool for discharging the medicine from the container main body. The two storage chambers are partitioned by a partition sealing portion in which the inner wall surfaces of the container body are heat-sealed. In use, the vicinity of the center of one of the storage chambers is pressed to increase the pressure in the storage chamber to open the partition sealing portion. As a result, the two storage chambers communicate with each other and the two drugs are mixed. Thereafter, the medicine discharge tool is opened by insertion or the like, and the mixed medicine is administered to the patient.

ところで、上記のような複室容器では、仕切り用封止部の開封前に、薬剤排出具を開封すると、混合前の薬剤が排出されるという問題があった。これを解決するため、例えば、特許文献1では、薬剤排出具に封止部材を係合させ、仕切り用封止部を開封する際に容器本体内に生じる圧力で封止部材が移動し薬剤排出具が開通する複室容器が提案されている。この封止部材を設けることで、仕切り用封止部の開封前に薬剤排出具を開封しても、封止部材によって収納室から薬剤が排出されるのを防止することができる。   By the way, in the multi-chamber container as described above, there is a problem that the medicine before mixing is discharged when the medicine discharging tool is opened before the partition sealing portion is opened. In order to solve this problem, for example, in Patent Document 1, the sealing member is moved by the pressure generated in the container body when the sealing member is engaged with the medicine discharging tool and the partition sealing portion is opened, and the medicine is discharged. Multi-chamber containers have been proposed in which tools are opened. By providing this sealing member, it is possible to prevent the medicine from being discharged from the storage chamber by the sealing member even if the medicine discharging tool is opened before the partition sealing portion is opened.

特開2005−28040号公報JP-A-2005-28040

しかしながら、上記特許文献1に記載の複室容器では、次のような問題を有している。すなわち、薬剤排出具に予め封止部材を取り付ける必要があるため、製造過程において、薬剤排出具から容器本体内に薬剤を注入することができないという問題がある。そのため、容器本体の一部を開封した状態で薬剤を注入し、薬剤投入後、容器本体の開封部を熱融着により封止する必要があった。そのため、複室容器の製造工程が複雑になるという問題がある。   However, the multi-chamber container described in Patent Document 1 has the following problems. That is, since it is necessary to attach a sealing member to the medicine discharging tool in advance, there is a problem that the medicine cannot be injected from the medicine discharging tool into the container body during the manufacturing process. Therefore, it is necessary to inject the medicine with a part of the container body opened, and to seal the opening portion of the container body by thermal fusion after the medicine is charged. Therefore, there exists a problem that the manufacturing process of a multi-chamber container becomes complicated.

本発明は、上記問題を解決するためになされたものであり、混合前の薬剤が排出されるのを防止でき、かつ、容易に製造可能な複室容器、及び当該複室容器に取り付けられる薬剤排出具を提供することを目的とする。   The present invention has been made to solve the above problems, and can prevent the medicine before mixing from being discharged, and can be easily manufactured, and the medicine attached to the multi-chamber container. The purpose is to provide a discharge device.

本発明は、薬剤を収納する複数の収納室、及び前記各収納室間を仕切る仕切り用封止部を備えた容器本体に取り付けられ、当該容器本体から薬剤を排出可能な薬剤排出具であって、前記容器本体側、及び当該容器本体から外部に露出する側を連通する第1及び第2の流路を有する排出具本体と、前記第1の流路における前記容器本体側の開口を塞ぎ、外力により当該開口を開くことが可能な第1の封止部材と、前記第2の流路における前記外部に露出する開口から挿入可能で、当該第2の流路を塞ぐ、第2封止部材と、前記第1及び第2の流路において、前記外部に露出する側の開口を塞ぐ栓部材と、を備えている。   The present invention is a drug discharger that is attached to a container main body having a plurality of storage chambers for storing a drug and a partition sealing portion that partitions the storage chambers, and is capable of discharging the drug from the container main body. A discharge tool body having first and second flow paths communicating with the container body side and a side exposed to the outside from the container body, and closing the opening on the container body side in the first flow path, A first sealing member that can open the opening by an external force, and a second sealing member that can be inserted from the opening exposed to the outside in the second flow path and closes the second flow path And a plug member for closing the opening exposed to the outside in each of the first and second flow paths.

この構成によれば、排出具本体に、2つの流路を設け、第1の流路を容器本体側から第1の封止部材で塞ぎ、第2の流路を容器本体の外部側から塞いでいるため、次の効果を得ることができる。まず、両流路を塞いでいるため、容器本体の仕切り用封止部を開封する前に栓部材を開いても、混合前の薬剤が排出されるのを防止することができる。そして、薬剤を排出するときには、第1の封止部材に外力を加えて、第1の流路を開封すればよい。また、第2の封止部材を、第2の流路において外部に露出する側の開口から挿入できるため、容器本体内に、第2の流路から薬剤を注入することができ、注入後に第2の封止部材で第2の流路を塞ぐことができる。その結果、容器本体の一部を開いて薬剤を注入するといった複雑な工程を経ることなく、薬剤排出具を介して容器本体内へ薬剤の注入が可能となる。なお、ここでいう「外力により開くことができる」とは、薬剤排出具の運搬中には開かないが積極的に外力を加えることにより開く程度の強度をいい、いわゆる弱シールである。この点については、本明細書を通じて同様の意味である。   According to this configuration, the discharge tool main body is provided with two flow paths, the first flow path is closed from the container main body side by the first sealing member, and the second flow path is closed from the outside of the container main body. Therefore, the following effects can be obtained. First, since both the flow paths are closed, it is possible to prevent the medicine before mixing from being discharged even if the stopper member is opened before the partition sealing portion of the container body is opened. And when discharging | emitting a chemical | medical agent, what is necessary is just to open an 1st flow path by applying external force to the 1st sealing member. In addition, since the second sealing member can be inserted from the opening on the side exposed to the outside in the second channel, the medicine can be injected into the container body from the second channel, The second flow path can be closed with two sealing members. As a result, the medicine can be injected into the container body via the medicine discharging tool without going through a complicated process of injecting the medicine by opening a part of the container body. Here, “can be opened by external force” means a strength that does not open during transportation of the medicine discharge tool but that can be opened by positively applying external force, and is a so-called weak seal. This point has the same meaning throughout this specification.

両流路は種々の構成をとることができるが、例えば、第2の流路を、排出具本体の中央に配置し、第1の流路で、第2の流路の周囲を囲むように配置することができる。これにより、第1の流路は、広い範囲に配置されるため、容器本体内の薬剤を排出しやすくなる。   Although both flow paths can take various configurations, for example, the second flow path is arranged in the center of the discharger main body, and the first flow path surrounds the periphery of the second flow path. Can be arranged. Thereby, since the 1st channel is arranged in a wide range, it becomes easy to discharge the medicine in a container main part.

また、第1の流路の総断面積を、第2の流路の総断面積よりも大きくすることができる。第2の流路の断面積は小さいが、これは一部の収納室に収納される薬剤を注入するからであり、通過する薬剤は少ない。一方、第1の流路は、複数の収納室の混合後の薬剤が通過するため、第2の流路を通過する薬剤よりも量が多い。よって、第2の流路の総断面積を大きくしておけば、薬剤をスムーズに排出することができる。   In addition, the total cross-sectional area of the first flow path can be made larger than the total cross-sectional area of the second flow path. Although the cross-sectional area of the second flow path is small, this is because the medicine stored in a part of the storage chambers is injected, and there are few drugs passing through. On the other hand, since the medicine after mixing of the plurality of storage chambers passes through the first flow path, the amount is larger than that of the medicine passing through the second flow path. Therefore, if the total cross-sectional area of the second channel is increased, the medicine can be discharged smoothly.

また、第1の流路及び第2の流路を、容器本体側から外部に露出する側へ延びる途中で合流させ、排出具本体において容器本体側から外部に露出する側に単一の開口を形成することができる。これにより、1つの栓部材で第1及び第2の流路を塞ぐことができ、薬剤の排出を確実に防止することができる。   Further, the first flow path and the second flow path are merged while extending from the container main body side to the side exposed to the outside, and a single opening is formed on the discharge tool main body on the side exposed from the container main body side to the outside. Can be formed. Thereby, the 1st and 2nd flow path can be plugged up with one plug member, and discharge of a medicine can be prevented certainly.

また、第1の封止部材も種々の形態にすることができる。例えば、貫通孔を有する円筒状に形成するとともに、軸方向に沿って2つに分割された第1の封止材及び第2の封止材で構成する。さらに、第1の流路を、第1及び第2の封止材によって塞ぎ、第1及び第2の封止材を、外力によって分離可能に互いに接続することができる。   Also, the first sealing member can be in various forms. For example, it is formed of a first sealing material and a second sealing material that are formed in a cylindrical shape having through holes and divided into two along the axial direction. Furthermore, the first flow path can be closed by the first and second sealing materials, and the first and second sealing materials can be connected to each other so as to be separable by an external force.

本発明に係る第1の複室容器は、薬剤を収納する複数の収納室、及び前記各収納室間を開封可能に仕切る仕切り用封止部を備えた容器本体と、前記容器本体に取り付けられ、当該容器本体から薬剤を排出可能な、上述した薬剤排出具と、を備えている。   A first multi-chamber container according to the present invention is attached to a container main body having a plurality of storage chambers for storing a medicine, and a partition sealing portion that partitions the storage chambers so as to be openable, and the container main body. And the above-described drug discharger capable of discharging the drug from the container main body.

また、本発明に係る第2の複室容器は、薬剤を収納する複数の収納室、及び前記各収納室間を開封可能に仕切る仕切り用封止部を備えた容器本体と、容器本体に取り付けられ、当該容器本体から薬剤を排出可能な、上述した封止材を有さない薬剤排出具と、を備え、前記第1の封止部材の少なくとも一部が、前記容器本体において互いに対向する内壁面の一方に固定されている。   In addition, a second multi-chamber container according to the present invention is attached to a container main body having a plurality of storage chambers for storing medicines, a partition sealing portion for partitioning the storage chambers in an openable manner, and the container main body. And a medicine discharger that does not have the above-described sealing material and can discharge the medicine from the container body, and at least a part of the first sealing member faces each other in the container body It is fixed to one side of the wall.

この構成によれば、第1の封止部材の少なくとも一部が、容器本体において互いに対向する内壁面の一方に固定されているため、次の効果を有する。すなわち、仕切り用封止部を開封するために、容器本体を押圧すると、内部の圧力が高まり、容器本体の端部において対向する内壁面同士が互いに離れていく。これにより、第1の封止部材が一方の内壁面側に引っ張られ、第1の流路を開封する。したがって、容器本体の押圧により、仕切り用封止部と、第1の流路との両方を同時に開封することができ、薬剤の排出操作を簡単にすることができる。なお、ここでいう「固定」とは、積極的な外力によっても外れない程度の強度をいい、いわゆる強シールである。この点については、第3及び第4の発明においても同じである。   According to this configuration, at least a part of the first sealing member is fixed to one of the inner wall surfaces facing each other in the container main body, and thus has the following effects. That is, when the container main body is pressed to open the partition sealing portion, the internal pressure increases, and the inner wall surfaces facing each other at the end of the container main body are separated from each other. Thereby, the 1st sealing member is pulled to one inner wall surface side, and the 1st channel is opened. Therefore, both the sealing part for a partition and the 1st flow path can be opened simultaneously by the press of a container main body, and discharge operation | movement of a chemical | medical agent can be simplified. Here, “fixed” refers to a strength that does not come off even by positive external force, and is a so-called strong seal. This is the same in the third and fourth inventions.

また、本発明に係る第3の複室容器は、薬剤を収納する複数の収納室、及び前記各収納室間を開封可能に仕切る仕切り用封止部を備えた容器本体と、前記容器本体に取り付けられ、当該容器本体から薬剤を排出可能な、上述した2つの封止材を有する薬剤排出具と、を備え、前記第1及び第2の封止材は、前記容器本体において互いに対向する内壁面のそれぞれに固定されている。   Further, a third multi-chamber container according to the present invention includes a container main body provided with a plurality of storage chambers for storing a medicine, and a partition sealing portion for partitioning the storage chambers in an openable manner, and the container main body. A medicine discharge tool having the two sealing materials described above, which is attached and capable of discharging the medicine from the container main body, and the first and second sealing materials are opposed to each other in the container main body. It is fixed to each of the wall surfaces.

この構成によれば、第1及び第2の封止材が、容器本体において互いに対向する内壁面のそれぞれに固定されているため、次の効果を有する。すなわち、容器本体を押圧すると、内部の圧力が高まり、容器本体の端部において対向する内壁面同士が互いに離れていくが、これにより、両封止材がそれぞれ各内壁面側に引っ張られる。その結果、両封止材が分離し、第1の流路が開封される。したがって、容器本体の押圧により、仕切り用封止部と、第1の流路の両方を同時に開封することができ、薬剤の排出操作を簡単にする。   According to this structure, since the 1st and 2nd sealing material is being fixed to each of the inner wall surface which mutually opposes in a container main body, it has the following effect. That is, when the container body is pressed, the internal pressure increases, and the inner wall surfaces facing each other at the end of the container body are separated from each other, whereby both sealing materials are pulled toward the inner wall surfaces. As a result, both sealing materials are separated, and the first flow path is opened. Therefore, both the sealing part for a partition and the 1st flow path can be opened simultaneously by the press of a container main body, and discharge operation | movement of a chemical | medical agent is simplified.

また、本発明に係る第4の複室容器は、薬剤を収納する複数の収納室、及び前記各収納室間を開封可能に仕切る仕切り用封止部を備えた容器本体と、前記容器本体に取り付けられ、当該容器本体から薬剤を排出可能な、上述した封止材を有さない薬剤排出具と、を備え、前記第1の封止部材は、前記第1の流路における前記容器本体側の開口を塞ぐ基部と、当該基部と連結される一対の連結片と、を備え、前記各連結片は、前記容器本体において互いに対向する内壁面のそれぞれに固定されている。   Further, a fourth multi-chamber container according to the present invention includes a container main body provided with a plurality of storage chambers for storing a medicine, and a partition sealing portion that partitions the storage chambers so as to be openable. And a medicine discharge tool that does not have the above-described sealing material and can be discharged from the container body, and the first sealing member is on the container body side in the first flow path And a pair of connecting pieces connected to the base, and the connecting pieces are fixed to inner wall surfaces facing each other in the container body.

この発明も、第2及び第3の発明と同様の効果を得ることができる。すなわち、容器本体を押圧すると、両連結片がそれぞれ各内壁面側に引っ張られるため、これによって、基部が引っ張られる。その結果、第1の流路が開封される。したがって、薬剤の排出操作を簡単にする。   This invention can also obtain the same effects as those of the second and third inventions. That is, when the container body is pressed, both the connecting pieces are pulled toward the respective inner wall surfaces, whereby the base is pulled. As a result, the first flow path is opened. Therefore, the medicine discharge operation is simplified.

さらに、本発明の第1から第4の複室容器は、前記容器本体を押圧すると、前記仕切り用封止部の開通とともに前記第1の封止部材が前記排出具本体から離脱し、前記第1の流路が開通される。   Furthermore, in the first to fourth multi-chamber containers of the present invention, when the container body is pressed, the first sealing member is detached from the discharger body together with the opening of the partition sealing portion, and the first 1 channel is opened.

この構成によれば、仕切り用封止部を開封するために行う容器本体の押圧により、第1の封止部材の開封を行うことができる。そのため、仕切り用封止部を開封する前に第1の封止部材のみを開封して混合前の薬剤を患者に投与してしまうことがなくなり、より確実に未開通投与を防止することができる。なお、「仕切り用封止部の開通とともに」とは、第1の封止部材が、仕切り用封止部の開通と同時に、又は、若干時間が前後して排出具本体から離脱することをいう。すなわち、仕切り用封止部及び第1の封止部材の開封のために容器本体を押圧している間に、仕切り用封止部及び第1の封止部材が開封されればよく、仕切り用封止部及び第1の封止部材の開封の順序は問わない。ただし、仕切り用封止部が開封した後に第1の封止部材が開封されるように構成される方が好ましい。この点については、本明細書を通じて同様の意味である。   According to this structure, the 1st sealing member can be opened by the press of the container main body performed in order to open the partition sealing part. Therefore, before opening the partition sealing part, only the first sealing member is not opened and the medicine before mixing is not administered to the patient, and unopened administration can be more reliably prevented. . The phrase “along with the opening of the partition sealing portion” means that the first sealing member is detached from the discharger main body simultaneously with the opening of the partition sealing portion or after some time. . That is, the partition sealing portion and the first sealing member only need to be opened while the container body is being pressed to open the partition sealing portion and the first sealing member. The order of opening the sealing portion and the first sealing member is not limited. However, it is preferable that the first sealing member is opened after the partition sealing portion is opened. This point has the same meaning throughout this specification.

本発明によれば、複数の薬剤が個別に収納された複室容器において、混合前の薬剤が排出されるのを防止することができ、かつ、容易に製造することができる。   ADVANTAGE OF THE INVENTION According to this invention, in the multi-chamber container in which the some chemical | medical agent was accommodated separately, it can prevent that the chemical | medical agent before mixing is discharged | emitted, and can manufacture easily.

本発明の複室容器の一実施形態を示す正面図である。It is a front view which shows one Embodiment of the multi-chamber container of this invention. 本発明の薬剤排出具の一実施形態を示す平面図及び断面正面図である。It is the top view and cross-sectional front view which show one Embodiment of the chemical | medical agent discharge tool of this invention. 図2の断面分解図である。FIG. 3 is an exploded sectional view of FIG. 2. 図2の薬剤排出具の動作を示す断面図である。It is sectional drawing which shows operation | movement of the chemical | medical agent discharge tool of FIG. 本発明の他の実施形態の薬剤排出具の動作を示す断面図である。It is sectional drawing which shows operation | movement of the chemical | medical agent discharge tool of other embodiment of this invention. 本発明の他の実施形態の薬剤排出具の動作を示す断面図である。It is sectional drawing which shows operation | movement of the chemical | medical agent discharge tool of other embodiment of this invention.

以下、本発明に係る複室容器の一実施形態について図面を参照しつつ説明する。図1は、本実施形態に係る複室容器の平面図である。   Hereinafter, an embodiment of a multi-chamber container according to the present invention will be described with reference to the drawings. FIG. 1 is a plan view of a multi-chamber container according to the present embodiment.

図1に示すように、この複室容器1は、矩形状の2枚のフィルムの周縁部2を熱融着して扁平の袋状に形成された容器本体3と、この容器本体3に取り付けられる薬剤排出具20とを備えている。   As shown in FIG. 1, the multi-chamber container 1 includes a container main body 3 formed in a flat bag shape by heat-sealing the peripheral edge portions 2 of two rectangular films, and is attached to the container main body 3. The medicine discharge tool 20 is provided.

容器本体3は、長手方向に並べて配置され薬剤が封入される第1収納室11及び第2収納室12を有しており、2つの収納室は仕切り用封止部13で仕切られている。また、薬剤排出具20は容器本体3における第2収納室側12の端部に接続されており、容器本体3から薬剤を排出する役割を果たす。一方、容器本体3において薬剤排出具20と反対側の端部には、複室容器1をフック等に吊り掛けるための吊掛孔14が周縁部2に形成されている。また、容器本体3において、第1収納室側11の端部には、吊掛孔14と隣接して薬剤注入具4が設けられている。この薬剤注入具4は、第1収納室11に薬剤を注入するためのものであり、薬剤が通過する筒状に形成され、ゴム栓40によって封止されている。   The container body 3 includes a first storage chamber 11 and a second storage chamber 12 that are arranged side by side in the longitudinal direction and enclose a medicine, and the two storage chambers are partitioned by a partition sealing portion 13. The medicine discharge tool 20 is connected to the end of the container body 3 on the second storage chamber side 12 and plays a role of discharging the medicine from the container body 3. On the other hand, a suspending hole 14 for suspending the multi-chamber container 1 on a hook or the like is formed in the peripheral edge 2 at the end of the container body 3 opposite to the medicine discharge tool 20. Further, in the container body 3, a drug injection tool 4 is provided at the end of the first storage chamber side 11 adjacent to the hanging hole 14. The drug injection tool 4 is for injecting a drug into the first storage chamber 11, is formed in a cylindrical shape through which the drug passes, and is sealed with a rubber plug 40.

容器本体3を構成するフィルムの材質としては、ポリエチレン、ポリプロピレン、ポリスチレン等の熱可塑性樹脂等、種々の樹脂材料を採用することができる。但し、後述するように仕切り用封止部13は容器本体3の内壁面同士を融着することから、容器本体3のフィルムは互いに相溶性が乏しく融点の異なる樹脂を混合した混合樹脂で形成することが好ましい。このようにすると、融着強度の制御が容易になるという利点がある。そのような樹脂の組み合わせとしては、例えば、スチレン系樹脂、メタクリル酸エステル系樹脂、環状オレフィン樹脂、ポリ4−メチルペンテン、ポリエステル、ポリアミド、又はポリプロピレンから選ばれる樹脂と、ポリエチレンとの混合樹脂を例示することができる。そのうち、ポリエチレンとポリプロピレンとの混合樹脂、及びポリエチレンと環状オレフィン樹脂との混合樹脂は、医療用として安全性が確認されていること、及び製造上の取り扱いが確立されていることから特に好ましい。   As a material of the film constituting the container body 3, various resin materials such as a thermoplastic resin such as polyethylene, polypropylene, and polystyrene can be employed. However, since the partition sealing portion 13 fuses the inner wall surfaces of the container body 3 as will be described later, the film of the container body 3 is formed of a mixed resin in which resins having poor compatibility and different melting points are mixed. It is preferable. In this way, there is an advantage that the fusion strength can be easily controlled. Examples of such resin combinations include a mixed resin of polyethylene and a resin selected from a styrene resin, a methacrylate ester resin, a cyclic olefin resin, poly-4-methylpentene, polyester, polyamide, or polypropylene. can do. Among them, a mixed resin of polyethylene and polypropylene and a mixed resin of polyethylene and cyclic olefin resin are particularly preferable because safety has been confirmed for medical use and handling in production has been established.

また、容器本体3を形成するフィルムは、上述した樹脂のみからなる単層のフィルムの他、多層構造のフィルムを使用することができる。この場合、容器本体3の最内層を構成する樹脂層が上記のような樹脂から形成されていればよい。   Moreover, the film which forms the container main body 3 can use the film of a multilayer structure other than the single layer film which consists only of resin mentioned above. In this case, the resin layer which comprises the innermost layer of the container main body 3 should just be formed from the above resins.

仕切り用封止部13は、上記のように容器本体3の内壁面同士を熱融着することで構成されており、収納室11、12の内圧を高めると開封するようになっている。このような融着強度としては、例えば、直径100mmの円板でいずれかの収納室を押圧し、10〜30kg程度の力をかけたときに仕切り用封止部13が開封するようなものが適当である。   The partition sealing portion 13 is configured by heat-sealing the inner wall surfaces of the container main body 3 as described above, and is opened when the internal pressure of the storage chambers 11 and 12 is increased. As such a fusion strength, for example, when one of the storage chambers is pressed with a disc having a diameter of 100 mm and a force of about 10 to 30 kg is applied, the partition sealing portion 13 is opened. Is appropriate.

仕切り用封止部13によって仕切られた各収納室11、12には、予め混合或いは溶解しておくとメイラード反応等の経時変化を起こすため隔離する必要がある各種薬剤a、bがそれぞれ封入されている。例えば、一方の収納室にアミノ酸を含有する溶液、他方の収納室にブドウ糖を含有する溶液を収納することができる。さらに、液剤だけでなく、いずれか一方の収納室に固形又は粉末薬剤を収納することもできる。但し、後述する開封操作を効率的に行うため、第2収納室12には液状の薬剤を収納しておくことが好ましい。   The storage chambers 11 and 12 partitioned by the partition sealing portion 13 are filled with various drugs a and b that need to be isolated in order to cause a change over time such as a Maillard reaction if mixed or dissolved in advance. ing. For example, a solution containing an amino acid can be stored in one storage chamber, and a solution containing glucose can be stored in the other storage chamber. Furthermore, not only a liquid agent but a solid or powder medicine can also be accommodated in any one storage chamber. However, in order to efficiently perform the opening operation described later, it is preferable to store a liquid medicine in the second storage chamber 12.

次に、薬剤排出具20について説明する。図2は薬剤排出具の一実施形態を示す平面図及び断面正面図であり、図3は図2の断面分解図、図4は図2の薬剤排出具の動作を示す断面図である。   Next, the medicine discharge tool 20 will be described. 2 is a plan view and a cross-sectional front view showing an embodiment of the medicine discharge tool, FIG. 3 is a sectional exploded view of FIG. 2, and FIG. 4 is a cross-sectional view showing the operation of the medicine discharge tool of FIG.

図2及び図3に示すように、薬剤排出具20は、円筒状の排出具本体21を備えており、この排出具本体21において、容器本体3に接続される端部に第1封止部材31が取り付けられ、外部に露出する端部にゴム栓40が取り付けられている。また、排出具本体21の内部には、第2封止部材32が取り付けられている。排出具本体21には、軸線方向に延びる断面円形の第1流路22及び第2流路23が形成されている。まず、第2流路23から説明する。第2流路23は、排出具本体21の両端部を連通するように延びており、外部に露出する側の開口をゴム栓40によって塞いでいる。また、この第2流路23は、排出具本体21の周方向の中央に配置されており、容器本体3側の端部では径が小さく、ゴム栓40側へ向かう途中で径が大きくなっている。一方、図2(a)に示すように、第1流路22は、容器本体3側の端部においては、第2流路23を囲むように、周方向に複数形成されている。そして、容器本体3側からゴム栓40側へ向かう途中で、径が大きくなっている第2流路23に連通している。   As shown in FIGS. 2 and 3, the drug discharger 20 includes a cylindrical discharger body 21, and a first sealing member is provided at an end of the discharger body 21 connected to the container body 3. 31 is attached, and a rubber plug 40 is attached to the end exposed to the outside. A second sealing member 32 is attached to the inside of the discharge tool main body 21. The discharge tool main body 21 is formed with a first flow path 22 and a second flow path 23 having a circular cross section extending in the axial direction. First, the second flow path 23 will be described. The second flow path 23 extends so as to communicate both ends of the discharge tool main body 21, and the rubber plug 40 closes the opening on the side exposed to the outside. Moreover, this 2nd flow path 23 is arrange | positioned in the center of the circumferential direction of the discharge tool main body 21, a diameter is small in the edge part by the side of the container main body 3, and a diameter becomes large on the way to the rubber stopper 40 side. Yes. On the other hand, as shown in FIG. 2A, a plurality of first flow paths 22 are formed in the circumferential direction so as to surround the second flow path 23 at the end on the container body 3 side. And in the middle from the container main body 3 side to the rubber plug 40 side, it communicates with the second flow path 23 having a large diameter.

第1封止部材31は、貫通孔311を有する円筒状に形成されており、排出具本体21とほぼ同一の外径を有するとともに、第1流路23とほぼ同一の内径を有している。この第1封止部材31は、排出具本体21の容器本体3側に融着されている。但し、外力を加えると、排出具本体21から離脱する程度の強度で排出具本体21に取り付けられている。また、第1封止部材31は、外形が排出具本体とほぼ一致するとともに、貫通孔311が第2流路23と一致するように取り付けられる。こうして、第1封止部材31の内壁面と外壁面との間の肉厚で周方向に亘って第1流路22が塞がれる。一方、第2封止部材32は、第2流路23における容器本体3側の端部に嵌め込まれており、これによって、第2流路23を塞いでいる。   The first sealing member 31 is formed in a cylindrical shape having a through hole 311, has substantially the same outer diameter as the discharge tool main body 21, and has substantially the same inner diameter as the first flow path 23. . The first sealing member 31 is fused to the container body 3 side of the discharge tool body 21. However, when an external force is applied, it is attached to the discharger main body 21 with such a strength that it is detached from the discharger main body 21. Further, the first sealing member 31 is attached so that the outer shape thereof substantially coincides with the discharger main body, and the through hole 311 coincides with the second flow path 23. In this way, the first flow path 22 is closed over the circumferential direction with the thickness between the inner wall surface and the outer wall surface of the first sealing member 31. On the other hand, the second sealing member 32 is fitted into the end of the second flow path 23 on the container body 3 side, thereby closing the second flow path 23.

次に、上記した複室容器の製造手順について説明する。まず、排出具本体21及び第1封止部材31を製造する。そして、排出具本体21と第1の封止部材31とを、上述したような強度で、離脱可能に融着する。次に、この排出具本体21と第1封止部材31とが融着されたものを、排出具本体21の一端部が第2収納室12に挿入し、他端部が容器本体3から外部に露出するように配置する。また、容器本体3の第1収納室11側には、薬剤注入具4を配置しておく。この状態で容器本体3の周縁部2、及び仕切り用封止部13を熱融着する。これにより、排出具本体21が容器本体3の周縁部2に取り付けられる。このとき、第1封止部材31は、図4(a)に示すように、容器本体3の一面3aと強い強度で融着されて強シールを形成し、容器本体3の他の一面3bと弱い強度で融着されて弱シールを形成する。また、薬剤注入具4も容器本体3の周縁部2に取り付けられる。こうして、容器本体3が形成されると、仕切り用封止部13によって仕切られた各収納室11、12に、上述した薬剤a、bを注入する。まず、第1収納室11に、薬剤注入具4から薬剤aを注入した後、図示を省略するゴム栓によって薬剤注入具4を封止する。   Next, the manufacturing procedure of the above-described multi-chamber container will be described. First, the discharge tool main body 21 and the first sealing member 31 are manufactured. And the discharge tool main body 21 and the 1st sealing member 31 are fuse | melted by the intensity | strength as mentioned above so that separation | detachment is possible. Next, after the discharge tool body 21 and the first sealing member 31 are fused, one end of the discharge tool body 21 is inserted into the second storage chamber 12 and the other end is externally connected from the container body 3. Arrange it so that it is exposed. In addition, the medicine injection device 4 is arranged on the container body 3 on the first storage chamber 11 side. In this state, the peripheral edge portion 2 of the container body 3 and the partition sealing portion 13 are heat-sealed. Thereby, the discharge tool main body 21 is attached to the peripheral edge 2 of the container main body 3. At this time, as shown in FIG. 4A, the first sealing member 31 is fused with one surface 3a of the container body 3 with a strong strength to form a strong seal, and the other surface 3b of the container body 3 It is fused with a weak strength to form a weak seal. Further, the medicine injection tool 4 is also attached to the peripheral edge 2 of the container body 3. Thus, when the container main body 3 is formed, the medicines a and b described above are injected into the storage chambers 11 and 12 partitioned by the partition sealing portion 13. First, after the drug a is injected from the drug injection tool 4 into the first storage chamber 11, the drug injection tool 4 is sealed with a rubber stopper (not shown).

次に、排出具本体21の外部に露出する端部、つまり第2流路23の端部から薬剤bを注入する。薬剤bは第2流路23、第1封止部材31の貫通孔311を経て、第2収納室12に注入される。このとき、第1流路22は、第1封止部材31によって容器本体3側の端部が封止されているので、薬剤bが第1流路22を介して容器本体3へ注入されるのが防止される。薬剤の充填工程終了及び窒素置換工程終了後に、第2封止部材32を真空装置でピックアップし、容器本体3側の小径の端部へ軽くセットする。そして、セットされた第2封止部材32を次の工程で定位置まで押し込み固定する。このとき、第2流路23は外部側の径が大きいため、第2封止部材32を挿入しやすくなっている。こうして、第2流路23が封止され、容器本体3から薬剤bが排出されるのを防止する。これに続いて、第2流路23の外部に露出する端部にゴム栓40を取り付ける。最後に、ゴム栓40が外れないように固定するため、排出具本体21の一端に設けられている係止片21aをゴム栓40の凹部40aに係合させるように成形する。   Next, the medicine b is injected from the end exposed to the outside of the discharge tool main body 21, that is, the end of the second flow path 23. The medicine b is injected into the second storage chamber 12 through the second flow path 23 and the through hole 311 of the first sealing member 31. At this time, since the first flow path 22 is sealed at the end on the container main body 3 side by the first sealing member 31, the medicine b is injected into the container main body 3 through the first flow path 22. Is prevented. After completion of the drug filling process and the nitrogen replacement process, the second sealing member 32 is picked up by a vacuum device and lightly set on the small diameter end on the container body 3 side. Then, the set second sealing member 32 is pushed and fixed to a fixed position in the next step. At this time, since the second channel 23 has a large outside diameter, the second sealing member 32 can be easily inserted. Thus, the second flow path 23 is sealed, and the medicine b is prevented from being discharged from the container body 3. Following this, a rubber plug 40 is attached to the end exposed to the outside of the second flow path 23. Finally, in order to fix the rubber plug 40 so as not to come off, the locking piece 21a provided at one end of the discharge tool body 21 is molded so as to be engaged with the recess 40a of the rubber plug 40.

続いて、上記のように構成された複室容器1の使用方法について説明する。複室容器1内の薬剤を患者に投与する前の状態においては、図4(a)に示すように、薬剤排出具20には、第1封止部材31及び第2封止部材32で封止されている。このとき、誤って先にゴム栓40に穿刺針を刺入したとしても、第1及び第2封止部材31、32によって第1及び第2の流路22、23が封止されているため、容器本体3内の薬剤が排出されることはない。そして、薬剤を患者に投与する際には、第2収納室12の中心部を押圧し、仕切り用封止部13を開封する。これにより、両収納室11,12の薬剤が混合される。このとき、第2収納室12が押圧されることにより、容器本体3の端部においては内壁面同士が互いに離れるように広がる。これにより、第1封止部材31は、強シールで融着されている部位に引っ張られ、弱シールで融着されている部位が剥離される。すなわち、仕切り用封止部13の開封と同時に第1封止部材31が排出具本体21から離脱し、第1流路22が開通する。続いて、ゴム栓40に刺入針を刺し込むと、混合された薬剤が排出される。また、万が一、仕切り用封止部13のみが開封され、第1封止部材31が開封されない場合であっても、第1封止部材31が容器本体3の内部に突出しているため、第1封止部材31を押圧するなど、直接外力を加えて開封し、第1流路22を開通することが可能である。   Then, the usage method of the multi-chamber container 1 comprised as mentioned above is demonstrated. In a state before the medicine in the multi-chamber container 1 is administered to the patient, the medicine discharging device 20 is sealed with a first sealing member 31 and a second sealing member 32 as shown in FIG. It has been stopped. At this time, even if the puncture needle is inserted into the rubber stopper 40 by mistake, the first and second flow paths 22 and 23 are sealed by the first and second sealing members 31 and 32. The medicine in the container body 3 is not discharged. And when administering a chemical | medical agent to a patient, the center part of the 2nd storage chamber 12 is pressed, and the sealing part 13 for partitions is opened. Thereby, the chemical | medical agent of both the storage chambers 11 and 12 is mixed. At this time, when the second storage chamber 12 is pressed, the inner wall surfaces of the end portion of the container main body 3 are spread apart from each other. Thereby, the 1st sealing member 31 is pulled by the site | part melt | fused by the strong seal, and the site | part melt | fusion by the weak seal is peeled. That is, the first sealing member 31 is detached from the discharger main body 21 simultaneously with the opening of the partition sealing portion 13, and the first flow path 22 is opened. Subsequently, when the insertion needle is inserted into the rubber stopper 40, the mixed medicine is discharged. In addition, even if only the partition sealing portion 13 is opened and the first sealing member 31 is not opened, the first sealing member 31 protrudes into the container main body 3. It is possible to open the first flow path 22 by directly applying an external force such as pressing the sealing member 31 to open the seal.

以上のように、本実施形態によれば、薬剤排出具20に、第1流路22及び第2流路23を形成し、第1流路22を予め第1の封止部材31で塞いでいる。そのため、製造時において、容器本体3の周縁部2及び仕切り用封止部13を熱融着して容器本体3を形成した後に、第2流路23を介して容器本体3に薬剤を注入することが可能となる。なお、第2流路23は、薬剤の注入後、第2封止部材によって封止されるため、容器本体3から薬剤が漏れることはない。このように、薬剤排出具20を挟んで外周部2を熱融着し、容器本体3を形成した後に、薬剤を投入することができるため、熱融着を行う工程が一度でよく、容易に容器本体3を製造することができる。加えて、第1封止部材31が第1の流路22を塞いでおり、第2封止部材32が第2の流路23を塞いでいるため、使用時に誤ってゴム栓40を先に開封しても薬剤は排出されず、第2収納室12に収納された混合前の薬剤が排出されるのを確実に防止することができる。   As described above, according to this embodiment, the first flow path 22 and the second flow path 23 are formed in the medicine discharge tool 20, and the first flow path 22 is closed in advance by the first sealing member 31. Yes. Therefore, at the time of manufacture, after the peripheral edge 2 of the container body 3 and the partition sealing part 13 are heat-sealed to form the container body 3, the drug is injected into the container body 3 through the second flow path 23. It becomes possible. In addition, since the 2nd flow path 23 is sealed by the 2nd sealing member after injection | pouring of a chemical | medical agent, a chemical | medical agent does not leak from the container main body 3. FIG. In this way, since the outer peripheral portion 2 is heat-sealed with the medicine discharger 20 interposed therebetween and the container body 3 is formed, the medicine can be charged, so that the heat-sealing process can be performed once and easily. The container body 3 can be manufactured. In addition, since the first sealing member 31 blocks the first flow path 22 and the second sealing member 32 blocks the second flow path 23, the rubber plug 40 is mistakenly inserted first before use. Even when opened, the medicine is not discharged, and it is possible to reliably prevent the medicine before mixing stored in the second storage chamber 12 from being discharged.

以上、本発明の一実施形態について説明したが、本発明は、これに限定されるものではなく、その趣旨を逸脱しない限りにおいて種々の変更が可能である。例えば、上記薬剤排出具20は、上記実施形態に限定されるものではなく、種々の形態を取り得ることができる。   As mentioned above, although one Embodiment of this invention was described, this invention is not limited to this, A various change is possible unless it deviates from the meaning. For example, the medicine discharge tool 20 is not limited to the above embodiment, and can take various forms.

例えば、上記実施形態では、第1封止部材31が一方に引っ張られる形態を示したが、図5に示すように、中央で割れるように形成してもよい。具体的には、図5(a)に示すように、第1封止部材51を、排出具本体21とほぼ同一の外径を有する管を円周方向に二つ割りに形成された第1封止材52及び第2封止材53とで形成し、第1及び第2封止材52、53の一方の端部に半月板54を取り付けて形成する。この半月板54には、第1及び第2封止材52、53を併せたときに、第2の流路23と概ね同一の直径を有する通液孔55が設けられる。この第1の封止部材51を、この第1の封止部材51と容器本体3とを強い強度で融着して強シールを形成し、第1封止材52と第2封止材53、及び、半月板54と排出具本体21とを弱い強度で融着して弱シールを形成する。このようにすると、図5(b)に示すように、仕切り用封止部13を開封するために第2収納室12を押圧することで、容器本体3の内壁面が互いに離れる際に、強シールに引っ張られて弱シールが剥離して、第1封止材52及び第2封止材53が分離し、かつ、半月板54が排出具本体21から剥離して、第1流路22が開通する。   For example, in the said embodiment, although the form in which the 1st sealing member 31 was pulled to one side was shown, as shown in FIG. 5, you may form so that it may crack in the center. Specifically, as shown in FIG. 5 (a), the first sealing member 51 is formed by dividing a pipe having an outer diameter substantially the same as that of the discharger main body 21 into two in the circumferential direction. The material 52 and the second sealing material 53 are formed, and the meniscus 54 is attached to one end of the first and second sealing materials 52 and 53. The meniscus 54 is provided with a liquid passage hole 55 having substantially the same diameter as the second flow path 23 when the first and second sealing materials 52 and 53 are combined. The first sealing member 51 and the container body 3 are fused with high strength to form a strong seal, and the first sealing member 52 and the second sealing member 53 are bonded together. And the meniscus 54 and the discharge tool main body 21 are fused with a weak strength to form a weak seal. If it does in this way, as shown in FIG.5 (b), when the inner wall surface of the container main body 3 leaves | separates mutually by pressing the 2nd storage chamber 12 in order to open the partition sealing part 13, it is strong. When pulled by the seal, the weak seal is peeled off, the first sealing material 52 and the second sealing material 53 are separated, and the meniscus 54 is peeled off from the discharger main body 21, so that the first flow path 22 is Open.

また、第1封止部材を、図6に示すように、フィルムで形成することもできる。具体的には、図6(a)に示すように、第1封止部材61を、矩形状の一対の側片(連結片)62と排出具本体21の外径とほぼ同一の一辺を有する方形の底部(基部)63とで形成し、底部63に第2の流路22とほぼ同一の直径を有する通液孔64を設ける。この第1封止部材61を、一対の側片62と容器本体3の対向する各内壁面とを強い強度で融着して強シールを形成し、底部63と排出具本体21とを弱い強度で融着して弱シールを形成する。このようにすると、図6(b)に示すように、仕切り用封止部13を開封するために第2収納室12を押圧することで、容器本体3の対向する内壁面が互いに離れる。これにより、強シールにより各側片62が引っ張られて、底部63が排出具本体から引っ張られる。これにより、弱シールが剥離し、第1流路22が開通する。   Further, the first sealing member can be formed of a film as shown in FIG. Specifically, as shown in FIG. 6A, the first sealing member 61 has one side that is substantially the same as the pair of rectangular side pieces (connecting pieces) 62 and the outer diameter of the discharger main body 21. The bottom 63 is formed with a rectangular bottom (base) 63, and a liquid passage hole 64 having the same diameter as that of the second flow path 22 is provided in the bottom 63. The first sealing member 61 is fused with a pair of side pieces 62 and the opposing inner wall surfaces of the container main body 3 with a strong strength to form a strong seal, and the bottom 63 and the discharger main body 21 are weakly strong. To form a weak seal. If it does in this way, as shown in FIG.6 (b), the inner wall surface which the container main body 3 opposes mutually will be left | separated by pressing the 2nd storage chamber 12 in order to open the sealing part 13 for a partition. Thereby, each side piece 62 is pulled by a strong seal, and the bottom 63 is pulled from the discharger main body. Thereby, a weak seal peels and the 1st channel 22 is opened.

さらに、上記実施形態では、複数の第1流路22を、第2流路23の周囲に配置しているが、例えば、第1流路と第2流路をそれぞれ一本ずつ配置して、それぞれが容器本体3側と、外部に露出する側とを連通するように形成することもできる。また、上記実施形態では、第1封止部材31を、容器本体3の内壁面に融着し、第2収納室12の押圧によって排出具本体21から離脱するようにしているが、第1封止部材31を、必ずしも容器本体3の内壁面に融着する必要はなく、手によって外力を加えて第1封止部材31を排出具本体21から離脱させてもよい。   Further, in the above embodiment, the plurality of first flow paths 22 are arranged around the second flow path 23. For example, the first flow path and the second flow path are arranged one by one, Each can be formed so that the container body 3 side communicates with the side exposed to the outside. In the above embodiment, the first sealing member 31 is fused to the inner wall surface of the container body 3 and is detached from the discharger body 21 by pressing the second storage chamber 12. The stop member 31 is not necessarily fused to the inner wall surface of the container body 3, and the first sealing member 31 may be detached from the discharger body 21 by applying an external force by hand.

また、上記実施形態では、薬剤が収納される収納室の数を2つにした容器本体について説明したが、これに限定されるものではなく、仕切り用封止部で仕切った3以上の収納室を設けることもできる。   Moreover, although the said embodiment demonstrated the container main body which made the number of the storage chambers in which a chemical | medical agent is stored in two, it is not limited to this, Three or more storage chambers divided by the sealing part for partitions Can also be provided.

1 複室容器
3 容器本体
11 第1収納室
12 第2収納室
13 仕切り用封止部
20 薬剤排出具
21 排出具本体
22 第1流路
23 第2流路
31、51、61 第1封止部材
32 第2封止部材
40 ゴム栓(栓部材)
52 第1封止材
53 第2封止材
62 側片(連結片)
63 底部(基部)
DESCRIPTION OF SYMBOLS 1 Multi-chamber container 3 Container main body 11 1st storage chamber 12 2nd storage chamber 13 Partition sealing part 20 Drug discharge tool 21 Discharge tool main body 22 1st flow path 23 2nd flow path 31,51,61 1st sealing Member 32 Second sealing member 40 Rubber stopper (plug member)
52 1st sealing material 53 2nd sealing material 62 Side piece (connection piece)
63 Bottom (base)

Claims (10)

薬剤を収納する複数の収納室、及び前記各収納室間を開封可能に仕切る仕切り用封止部を備えた容器本体に取り付けられ、当該容器本体から薬剤を排出可能な薬剤排出具であって、
前記容器本体側、及び当該容器本体から外部に露出する側を連通する、少なくとも1つの第1及び第2の流路を有する排出具本体と、
前記第1の流路における前記容器本体側の開口を塞ぎ、外力により当該開口を開くことが可能な第1の封止部材と、
前記第2の流路における前記外部に露出する開口から挿入可能で、当該第2の流路を塞ぐ、第2の封止部材と、
前記第1及び第2の流路において、前記外部に露出する側の開口を塞ぐ栓部材と、
を備えている、薬剤排出具。
A plurality of storage chambers for storing a drug, and a drug discharger that is attached to a container main body provided with a partition sealing portion that partitions the storage chambers so as to be openable, and can discharge the drug from the container main body,
An ejector body having at least one first and second flow paths communicating with the container body side and the side exposed to the outside from the container body;
A first sealing member capable of closing the opening on the container body side in the first flow path and opening the opening by an external force;
A second sealing member that can be inserted from the opening exposed to the outside in the second flow path and closes the second flow path;
A plug member for closing the opening on the side exposed to the outside in the first and second flow paths;
A drug discharger.
前記第2の流路は、前記排出具本体の中央に配置され、
前記第1の流路は、前記第2の流路の周囲を囲むように配置されている、請求項1に記載の薬剤排出具。
The second flow path is disposed at the center of the discharge tool body,
The medicine discharge tool according to claim 1, wherein the first flow path is disposed so as to surround the periphery of the second flow path.
前記第1の流路の総断面積は、前記第2の流路の総断面積よりも大きい、請求項1または2に記載の薬剤排出具。   The medicine discharge tool according to claim 1 or 2, wherein a total cross-sectional area of the first flow path is larger than a total cross-sectional area of the second flow path. 前記第1及び第2の流路は、前記容器本体側から外部に露出する側へ延びる途中で合流し、前記排出具本体において前記容器本体側から外部に露出する側に単一の開口が形成され、前記栓部材は当該単一の開口に取り付けられる、請求項1から3のいずれかに記載の薬剤排出具。   The first and second flow paths merge while extending from the container body side to the side exposed to the outside, and a single opening is formed on the discharge tool body on the side exposed from the container body side to the outside. The medicine discharge tool according to any one of claims 1 to 3, wherein the stopper member is attached to the single opening. 前記第1の封止部材は、貫通孔を有する円筒状に形成されるとともに、軸方向に沿って2つに分割された第1の封止材及び第2の封止材で構成され、
前記第1の流路は、前記第1及び第2の封止材によって塞がれ、
前記第1及び第2の封止材は、外力によって分離可能に互いに接続されている、請求項1から4のいずれかに記載の薬剤排出具。
The first sealing member is formed of a first sealing material and a second sealing material which are formed in a cylindrical shape having a through hole and divided into two along the axial direction.
The first flow path is blocked by the first and second sealing materials,
The medicine discharging tool according to any one of claims 1 to 4, wherein the first and second sealing materials are connected to each other so as to be separable by an external force.
薬剤を収納する複数の収納室、及び前記各収納室間を開封可能に仕切る仕切り用封止部を備えた容器本体と、
前記容器本体に取り付けられ、当該容器本体から薬剤を排出可能な、請求項1から5のいずれかに記載の薬剤排出具と、
を備えている、複室容器。
A plurality of storage chambers for storing medicines, and a container main body provided with a partition sealing portion for partitioning the storage chambers in an openable manner;
The medicine discharge tool according to any one of claims 1 to 5, which is attached to the container body and capable of discharging the medicine from the container body.
A multi-chamber container.
薬剤を収納する複数の収納室、及び前記各収納室間を開封可能に仕切る仕切り用封止部を備えた容器本体と、
前記容器本体に取り付けられ、当該容器本体から薬剤を排出可能な、請求項1から4のいずれかに記載の薬剤排出具と、
を備え、
前記第1の封止部材の少なくとも一部が、前記容器本体において互いに対向する内壁面の一方に固定されている、複室容器。
A plurality of storage chambers for storing medicines, and a container main body provided with a partition sealing portion for partitioning the storage chambers in an openable manner;
The drug discharge tool according to any one of claims 1 to 4, which is attached to the container body and capable of discharging the drug from the container body.
With
A multi-chamber container in which at least a part of the first sealing member is fixed to one of mutually opposing inner wall surfaces in the container body.
薬剤を収納する複数の収納室、及び前記各収納室間を開封可能に仕切る仕切り用封止部を備えた容器本体と、
前記容器本体に取り付けられ、当該容器本体から薬剤を排出可能な、請求項5に記載の薬剤排出具と、
を備え、
前記第1及び第2の封止材は、前記容器本体において互いに対向する内壁面のそれぞれに固定されている、複室容器。
A plurality of storage chambers for storing medicines, and a container main body provided with a partition sealing portion for partitioning the storage chambers in an openable manner;
The medicine discharge tool according to claim 5, attached to the container body and capable of discharging the medicine from the container body,
With
The said 1st and 2nd sealing material is a multi-chamber container fixed to each of the inner wall surface which mutually opposes in the said container main body.
薬剤を収納する複数の収納室、及び前記各収納室間を開封可能に仕切る仕切り用封止部を備えた容器本体と、
前記容器本体に取り付けられ、当該容器本体から薬剤を排出可能な、請求項1から4のいずれかに記載の薬剤排出具と、
を備え、
前記第1の封止部材は、前記第1の流路における前記容器本体側の開口を塞ぐ基部と、当該基部と連結される一対の連結片と、を備え、
前記各連結片は、前記容器本体において互いに対向する内壁面のそれぞれに固定されている、複室容器。
A plurality of storage chambers for storing medicines, and a container main body provided with a partition sealing portion for partitioning the storage chambers in an openable manner;
The drug discharge tool according to any one of claims 1 to 4, which is attached to the container body and capable of discharging the drug from the container body.
With
The first sealing member includes a base portion that closes the opening on the container body side in the first flow path, and a pair of connecting pieces that are connected to the base portion.
Each said connection piece is a multi-chamber container fixed to each of the inner wall surfaces which mutually oppose in the said container main body.
前記容器本体を押圧すると、前記仕切り用封止部の開通とともに前記第1の封止部材が前記排出具本体から離脱し、前記第1の流路が開通する、請求項6から9のいずれかに記載の複室容器。   10. The device according to claim 6, wherein when the container main body is pressed, the first sealing member is detached from the discharger main body together with the opening of the partition sealing portion, and the first flow path is opened. A multi-chamber container described in 1.
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013169187A (en) * 2012-02-21 2013-09-02 Jms Co Ltd Cell preservation container
WO2015050255A1 (en) 2013-10-04 2015-04-09 森下仁丹株式会社 Seamless capsule for extermination of harmful insects

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004248892A (en) * 2003-02-20 2004-09-09 Terumo Corp Medical container
WO2005023665A1 (en) * 2003-09-02 2005-03-17 Otsuka Pharmaceutical Co., Ltd. Discharge member, discharge container having the discharge member, and instillation container
JP2006507914A (en) * 2002-11-28 2006-03-09 株式会社大塚製薬工場 Medical multi-chamber container and manufacturing method thereof
JP2006087904A (en) * 2004-08-25 2006-04-06 Terumo Corp Cylindrical body for medical container, drug container for medical container, discharge port for medical container and medical container
WO2009011179A1 (en) * 2007-07-17 2009-01-22 Ajinomoto Co., Inc. Double-chamber container
JP2010076802A (en) * 2008-09-25 2010-04-08 Jms Co Ltd Medical port with cap

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006507914A (en) * 2002-11-28 2006-03-09 株式会社大塚製薬工場 Medical multi-chamber container and manufacturing method thereof
JP2004248892A (en) * 2003-02-20 2004-09-09 Terumo Corp Medical container
WO2005023665A1 (en) * 2003-09-02 2005-03-17 Otsuka Pharmaceutical Co., Ltd. Discharge member, discharge container having the discharge member, and instillation container
JP2006087904A (en) * 2004-08-25 2006-04-06 Terumo Corp Cylindrical body for medical container, drug container for medical container, discharge port for medical container and medical container
WO2009011179A1 (en) * 2007-07-17 2009-01-22 Ajinomoto Co., Inc. Double-chamber container
JP2010076802A (en) * 2008-09-25 2010-04-08 Jms Co Ltd Medical port with cap

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013169187A (en) * 2012-02-21 2013-09-02 Jms Co Ltd Cell preservation container
WO2015050255A1 (en) 2013-10-04 2015-04-09 森下仁丹株式会社 Seamless capsule for extermination of harmful insects
KR20160070775A (en) 2013-10-04 2016-06-20 모리시타 진탄 가부시키가이샤 Seamless capsule for extermination of harmful insects
CN106028803A (en) * 2013-10-04 2016-10-12 森下仁丹株式会社 Seamless capsule for extermination of harmful insects

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