JP2011144201A5 - - Google Patents
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- Publication number
- JP2011144201A5 JP2011144201A5 JP2011093677A JP2011093677A JP2011144201A5 JP 2011144201 A5 JP2011144201 A5 JP 2011144201A5 JP 2011093677 A JP2011093677 A JP 2011093677A JP 2011093677 A JP2011093677 A JP 2011093677A JP 2011144201 A5 JP2011144201 A5 JP 2011144201A5
- Authority
- JP
- Japan
- Prior art keywords
- medicament
- use according
- respiratory
- asthma
- administered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 claims 7
- 206010038683 Respiratory disease Diseases 0.000 claims 4
- 208000006673 Asthma Diseases 0.000 claims 3
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 2
- 241000709661 Enterovirus Species 0.000 claims 2
- 102100015720 IFNB1 Human genes 0.000 claims 2
- 101700011451 IFNB1 Proteins 0.000 claims 2
- 210000002345 respiratory system Anatomy 0.000 claims 2
- 210000000981 Epithelium Anatomy 0.000 claims 1
- 102000003996 Interferon beta Human genes 0.000 claims 1
- 108090000467 Interferon beta Proteins 0.000 claims 1
- 229960001388 Interferon-beta Drugs 0.000 claims 1
- 239000000443 aerosol Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000003246 corticosteroid Substances 0.000 claims 1
- 229940079593 drugs Drugs 0.000 claims 1
- 230000005713 exacerbation Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000006199 nebulizer Substances 0.000 claims 1
- 229920000023 polynucleotide Polymers 0.000 claims 1
- 239000002157 polynucleotide Substances 0.000 claims 1
- 230000002685 pulmonary Effects 0.000 claims 1
Claims (6)
- 喘息及び慢性閉塞性肺疾患(COPD)から選択される呼吸器疾患のライノウイルスが誘発する増悪を治療するための医薬の製造における、
(a)内在性インターフェロンβ(IFN-β)の発現を増加させる薬剤、又は、
(b)(a)の薬剤を発現できるポリヌクレオチド、
の使用であって、前記医薬は下気道に投与されるものであり、且つ前記医薬の投与により個体におけるライノウイルス複製が抑制される、前記使用。 - 前記呼吸器疾患が喘息である、請求項１記載の使用。
- 前記呼吸器疾患がCOPDである、請求項１記載の使用。
- 前記呼吸器疾患が喘息であり、且つ前記医薬が吸入コルチコステロイドと同時に、別々に又は逐次的に投与されるものである、請求項２記載の使用。
- 前記医薬がエアロゾル噴霧器により肺気道に投与されるものである、請求項１記載の使用。
- 前記薬剤が気管支上皮において内在性IFN-βの発現を増加させる、請求項１〜５のいずれか１項記載の使用。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0405634.7A GB0405634D0 (en) | 2004-03-12 | 2004-03-12 | Anti-virus therapy for respiratory diseases |
| GB0405634.7 | 2004-03-12 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007502414A Division JP4807526B2 (ja) | 2004-03-12 | 2005-03-07 | 呼吸器疾患の抗ウイルス療法のためのインターフェロン−β |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011144201A JP2011144201A (ja) | 2011-07-28 |
| JP2011144201A5 true JP2011144201A5 (ja) | 2012-10-18 |
Family
ID=32117582
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007502414A Expired - Fee Related JP4807526B2 (ja) | 2004-03-12 | 2005-03-07 | 呼吸器疾患の抗ウイルス療法のためのインターフェロン−β |
| JP2011093677A Pending JP2011144201A (ja) | 2004-03-12 | 2011-04-20 | 呼吸器疾患の抗ウイルス療法のためのインターフェロン−β |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007502414A Expired - Fee Related JP4807526B2 (ja) | 2004-03-12 | 2005-03-07 | 呼吸器疾患の抗ウイルス療法のためのインターフェロン−β |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US7569216B2 (ja) |
| EP (2) | EP2206512A3 (ja) |
| JP (2) | JP4807526B2 (ja) |
| AT (1) | ATE466591T1 (ja) |
| CA (2) | CA2558212C (ja) |
| DE (1) | DE602005021078D1 (ja) |
| DK (1) | DK1734987T3 (ja) |
| ES (1) | ES2343732T3 (ja) |
| GB (1) | GB0405634D0 (ja) |
| HK (1) | HK1097181A1 (ja) |
| PL (1) | PL1734987T3 (ja) |
| PT (1) | PT1734987E (ja) |
| WO (1) | WO2005087253A2 (ja) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0405634D0 (en) | 2004-03-12 | 2004-04-21 | Univ Southampton | Anti-virus therapy for respiratory diseases |
| US8318423B2 (en) * | 2004-07-06 | 2012-11-27 | Focus Diagnostics, Inc. | Methods and compositions for detecting rhinoviruses |
| EP1922081B1 (en) * | 2005-09-09 | 2012-08-15 | Imperial Innovations Limited | Interferon lambda therapy for treatment of respiratory diseases |
| JP5175198B2 (ja) | 2005-09-20 | 2013-04-03 | ニューヨーク・ユニバーシティ | インターフェロンを用いる肺疾患の処置方法 |
| DE102006022877B4 (de) | 2006-05-15 | 2009-01-29 | Sartorius Stedim Biotech Gmbh | Verfahren zur Bestimmung der Viabilität von Zellen in Zellkulturen |
| US7871603B2 (en) | 2007-05-18 | 2011-01-18 | Synairgen Research Limited | Interferon-beta and/or lambda for use in treating rhinovirus infection in the elderly |
| GB0713402D0 (en) * | 2007-07-11 | 2007-08-22 | Cardiff & Vale Nhs Trust | A method of diagnosing a condition using a neural network |
| CN102131827A (zh) * | 2007-12-13 | 2011-07-20 | 葛兰素集团有限公司 | 用于肺部传递给药的组合物 |
| CA2744947A1 (en) * | 2008-12-19 | 2010-10-28 | The Regents Of The University Of California | Use of epidermal growth factor inhibitors in the treatment of viral infection |
| US9492095B2 (en) | 2009-12-02 | 2016-11-15 | Neetour Medical Ltd. | Hemodynamics-based monitoring and evaluation of a respiratory condition |
| ES2592528T3 (es) | 2010-03-12 | 2016-11-30 | Synairgen Research Limited | Interferón beta para uso en el tratamiento de enfermedades de las vías respiratorias inferiores causada por influenza |
| JP2013537892A (ja) | 2010-09-22 | 2013-10-07 | ザ ユニバーシティー オブ メルボルン | 新規な免疫賦活法 |
| EP3954714A1 (en) | 2014-01-08 | 2022-02-16 | Prosit Sole Biotechnology (Beijing) Co. Ltd | Fusion polypeptides and methods of use |
| WO2019023196A1 (en) * | 2017-07-24 | 2019-01-31 | Novavax, Inc. | METHODS AND COMPOSITIONS FOR TREATING RESPIRATORY DISEASE |
| EP3923975A4 (en) * | 2019-02-13 | 2023-04-19 | University of Florida Research Foundation, Inc. | TARGETING A LUNG-RESIDENT TNFR2+ CDC2 (R2D2) SUBPOPULATION TO TREAT ASTHMA |
| CA3142501A1 (en) | 2019-06-26 | 2020-12-30 | Axelia Oncology Pty Ltd | Novel molecules |
| JP2023535710A (ja) | 2020-07-20 | 2023-08-21 | シナーゲン リサーチ リミテッド | ＳＡＲＳ－ＣｏＶ－２感染患者におけるアウトカムを改善するための吸入インターフェロン－ベータ |
| GB202014114D0 (en) | 2020-09-08 | 2020-10-21 | Synairgen Res Ltd | Use of inhaled interferon-beta to treat virus-induced exacerbations in copd patients undergoing treatment with a systemic corticosteroid |
| WO2022096582A1 (en) * | 2020-11-04 | 2022-05-12 | Ethris Gmbh | Use of ifn-lambda mrna for treating viral infections |
| CN117545500A (zh) * | 2021-01-13 | 2024-02-09 | 瑷备恩有限公司 | 针对呼吸道病毒的预防性施用方法，包括向潜在的呼吸道病毒感染对象施用干扰素β |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6596260B1 (en) * | 1993-08-27 | 2003-07-22 | Novartis Corporation | Aerosol container and a method for storage and administration of a predetermined amount of a pharmaceutically active aerosol |
| AU696387B2 (en) * | 1994-05-18 | 1998-09-10 | Inhale Therapeutic Systems, Inc. | Methods and compositions for the dry powder formulation of interferons |
| US6030609A (en) | 1995-05-19 | 2000-02-29 | Case Western Reserve University | Method and composition for treating paramyxovirus |
| US20010031253A1 (en) * | 1996-07-24 | 2001-10-18 | Gruenberg Micheal L. | Autologous immune cell therapy: cell compositions, methods and applications to treatment of human disease |
| AU780270B2 (en) * | 2000-02-23 | 2005-03-10 | Association Francaise Contre Les Myopathies | Treatment of immune diseases |
| GB2362884A (en) | 2000-05-30 | 2001-12-05 | Isis Innovation | Extended duration of airway gene therapy |
| AU2002212107A1 (en) | 2000-11-02 | 2002-05-15 | Maxygen Aps | New multimeric interferon beta polypeptides |
| WO2002072019A2 (en) * | 2001-03-13 | 2002-09-19 | Vical Incorporated | Interferon-beta polynucleotide therapy for autoimmune and inflammatory diseases |
| US7820793B2 (en) | 2002-02-08 | 2010-10-26 | University Of Medicine And Dentistry Of New Jersey | IFN-λ polypeptides and compositions |
| US20040037809A1 (en) * | 2002-06-28 | 2004-02-26 | Nastech Pharmaceutical Company Inc. | Compositions and methods for enhanced mucosal delivery of interferon beta |
| EP1575609A4 (en) | 2002-10-23 | 2010-12-15 | Zymogenetics L L C | METHOD FOR THE TREATMENT OF VIRUS INFECTIONS USING IL-28 AND IL-29 |
| ES2303132T3 (es) | 2003-08-07 | 2008-08-01 | Zymogenetics, Inc. | Preparaciones homogeneas de il-29. |
| GB0405634D0 (en) | 2004-03-12 | 2004-04-21 | Univ Southampton | Anti-virus therapy for respiratory diseases |
| CA2558829C (en) | 2004-04-02 | 2014-03-11 | Zymogenetics, Inc. | Methods for treating viral infection using il-28 and il-29 cysteine mutants |
-
2004
- 2004-03-12 GB GBGB0405634.7A patent/GB0405634D0/en not_active Ceased
-
2005
- 2005-03-07 PL PL05708482T patent/PL1734987T3/pl unknown
- 2005-03-07 AT AT05708482T patent/ATE466591T1/de active
- 2005-03-07 CA CA2558212A patent/CA2558212C/en active Active
- 2005-03-07 PT PT05708482T patent/PT1734987E/pt unknown
- 2005-03-07 DK DK05708482.4T patent/DK1734987T3/da active
- 2005-03-07 EP EP10161661A patent/EP2206512A3/en not_active Withdrawn
- 2005-03-07 WO PCT/GB2005/050031 patent/WO2005087253A2/en not_active Application Discontinuation
- 2005-03-07 ES ES05708482T patent/ES2343732T3/es active Active
- 2005-03-07 EP EP05708482A patent/EP1734987B1/en active Active
- 2005-03-07 DE DE602005021078T patent/DE602005021078D1/de active Active
- 2005-03-07 CA CA2787978A patent/CA2787978A1/en not_active Abandoned
- 2005-03-07 JP JP2007502414A patent/JP4807526B2/ja not_active Expired - Fee Related
-
2006
- 2006-09-08 US US11/517,763 patent/US7569216B2/en active Active
-
2007
- 2007-04-20 HK HK07104017.4A patent/HK1097181A1/xx not_active IP Right Cessation
-
2009
- 2009-06-18 US US12/487,563 patent/US8273342B2/en active Active
-
2011
- 2011-04-20 JP JP2011093677A patent/JP2011144201A/ja active Pending
-
2012
- 2012-08-16 US US13/587,752 patent/US9089535B2/en not_active Expired - Fee Related
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