JP2011050292A5 - - Google Patents

Info

Publication number

JP2011050292A5

JP2011050292A5 JP2009201114A JP2009201114A JP2011050292A5 JP 2011050292 A5 JP2011050292 A5 JP 2011050292A5 JP 2009201114 A JP2009201114 A JP 2009201114A JP 2009201114 A JP2009201114 A JP 2009201114A JP 2011050292 A5 JP2011050292 A5 JP 2011050292A5

Authority

JP

Japan

Prior art keywords

polypeptide

acid sequence

amino acid

fusion protein

protein

Prior art date

2009-08-31

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
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• 206010028980 Neoplasm Diseases 0.000 claims description 8
• 230000027455 binding Effects 0.000 claims description 3
• 201000011510 cancer Diseases 0.000 claims description 3
• 230000000694 effects Effects 0.000 claims description 2
• 201000001441 melanoma Diseases 0.000 claims description 2
• 229920001184 polypeptide Polymers 0.000 claims 25
• 108090000765 processed proteins & peptides Proteins 0.000 claims 25
• 102000004196 processed proteins & peptides Human genes 0.000 claims 25
• 125000003275 alpha amino acid group Chemical group 0.000 claims 19
• 108020001507 fusion proteins Proteins 0.000 claims 18
• 102000037865 fusion proteins Human genes 0.000 claims 18
• 150000001413 amino acids Chemical class 0.000 claims 12
• 108090000623 proteins and genes Proteins 0.000 claims 9
• 102000004169 proteins and genes Human genes 0.000 claims 9
• 101710133291 Hemagglutinin-neuraminidase Proteins 0.000 claims 8
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 6
• 102100037850 Interferon gamma Human genes 0.000 claims 6
• 108010074328 Interferon-gamma Proteins 0.000 claims 6
• 230000001737 promoting effect Effects 0.000 claims 6
• 230000028327 secretion Effects 0.000 claims 6
• 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 4
• 239000002246 antineoplastic agent Substances 0.000 claims 3
• 239000004480 active ingredient Substances 0.000 claims 2
• 206010005003 Bladder cancer Diseases 0.000 claims 1
• 206010009944 Colon cancer Diseases 0.000 claims 1
• 206010060862 Prostate cancer Diseases 0.000 claims 1
• 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
• 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 1
• 210000004899 c-terminal region Anatomy 0.000 claims 1
• 208000029742 colonic neoplasm Diseases 0.000 claims 1
• 238000000034 method Methods 0.000 claims 1
• 102000039446 nucleic acids Human genes 0.000 claims 1
• 108020004707 nucleic acids Proteins 0.000 claims 1
• 150000007523 nucleic acids Chemical class 0.000 claims 1
• 230000002265 prevention Effects 0.000 claims 1
• 230000001568 sexual effect Effects 0.000 claims 1
• 201000005112 urinary bladder cancer Diseases 0.000 claims 1
• 230000001093 anti-cancer Effects 0.000 description 3
• 241000699670 Mus sp. Species 0.000 description 2
• 241000699666 Mus <mouse, genus> Species 0.000 description 1
• 230000000259 anti-tumor effect Effects 0.000 description 1
• 239000004148 curcumin Substances 0.000 description 1
• 239000011259 mixed solution Substances 0.000 description 1