JP2011026335A5 - - Google Patents
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- Publication number
- JP2011026335A5 JP2011026335A5 JP2010223566A JP2010223566A JP2011026335A5 JP 2011026335 A5 JP2011026335 A5 JP 2011026335A5 JP 2010223566 A JP2010223566 A JP 2010223566A JP 2010223566 A JP2010223566 A JP 2010223566A JP 2011026335 A5 JP2011026335 A5 JP 2011026335A5
- Authority
- JP
- Japan
- Prior art keywords
- tablet
- progesterone
- vaginal administration
- administration according
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 claims 25
- 229960003387 progesterone Drugs 0.000 claims 11
- 239000000186 progesterone Substances 0.000 claims 11
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 4
- WNLRTRBMVRJNCN-UHFFFAOYSA-N adipic acid Chemical compound OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 claims 4
- 239000004088 foaming agent Substances 0.000 claims 4
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims 4
- 229960001207 micronized progesterone Drugs 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 2
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 2
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 claims 2
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims 2
- 229920002472 Starch Polymers 0.000 claims 2
- 241000209149 Zea Species 0.000 claims 2
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims 2
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims 2
- 235000011037 adipic acid Nutrition 0.000 claims 2
- 239000001361 adipic acid Substances 0.000 claims 2
- 235000005822 corn Nutrition 0.000 claims 2
- 238000009434 installation Methods 0.000 claims 2
- 239000008101 lactose Substances 0.000 claims 2
- 235000019359 magnesium stearate Nutrition 0.000 claims 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 2
- 229940069328 povidone Drugs 0.000 claims 2
- 239000000377 silicon dioxide Substances 0.000 claims 2
- 235000019333 sodium laurylsulphate Nutrition 0.000 claims 2
- 239000008107 starch Substances 0.000 claims 2
- 235000019698 starch Nutrition 0.000 claims 2
- 210000001215 vagina Anatomy 0.000 claims 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims 1
- 208000034423 Delivery Diseases 0.000 claims 1
- 238000007907 direct compression Methods 0.000 claims 1
- 238000001599 direct drying Methods 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 230000009677 vaginal delivery Effects 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL12712998A IL127129A (en) | 1998-11-18 | 1998-11-18 | Method for preparation of progesterone tablets for vaginal delivery and tablets so prepared |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000582018A Division JP4667601B2 (ja) | 1998-11-18 | 1999-11-17 | プロゲステロン含有経膣投与用錠剤およびその調製法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011026335A JP2011026335A (ja) | 2011-02-10 |
| JP2011026335A5 true JP2011026335A5 (cg-RX-API-DMAC7.html) | 2012-01-26 |
Family
ID=11072154
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000582018A Expired - Lifetime JP4667601B2 (ja) | 1998-11-18 | 1999-11-17 | プロゲステロン含有経膣投与用錠剤およびその調製法 |
| JP2010223566A Pending JP2011026335A (ja) | 1998-11-18 | 2010-10-01 | プロゲステロン含有経膣投与用錠剤およびその調製法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000582018A Expired - Lifetime JP4667601B2 (ja) | 1998-11-18 | 1999-11-17 | プロゲステロン含有経膣投与用錠剤およびその調製法 |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US7300664B1 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2386291A1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP4667601B2 (cg-RX-API-DMAC7.html) |
| AU (1) | AU1176200A (cg-RX-API-DMAC7.html) |
| DK (1) | DK1131052T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2390959T3 (cg-RX-API-DMAC7.html) |
| IL (1) | IL127129A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2000028970A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL127129A (en) * | 1998-11-18 | 2004-06-01 | Ferring Bv | Method for preparation of progesterone tablets for vaginal delivery and tablets so prepared |
| FR2821555B1 (fr) | 2001-03-01 | 2003-05-16 | Besins Int Lab | Progestatif co-micronise avec un tensioactif, composition pharmaceutique le comprenant, leurs procedes de fabrication et leurs utilisations |
| JP2006511624A (ja) * | 2002-12-20 | 2006-04-06 | ダイノジェン ファーマシューティカルズ， インコーポレイテッド | α２δサブユニット・カルシウム・チャンネル調節因子を使用する無痛性膀胱障害を処置するための方法 |
| PL1492519T3 (pl) * | 2003-03-21 | 2007-04-30 | Dynogen Pharmaceuticals Inc | Sposób leczenia chorób dolnych dróg moczowych przez zastosowanie modulatorów podjednostki α2δ kanału wapniowego z modulatorami mięśni gładkich |
| DE10316583A1 (de) * | 2003-04-10 | 2004-10-28 | B.R.A.H.M.S Aktiengesellschaft | Bestimmung eines midregionalen Proadrenomedullin-Teilpeptids in biologischen Flüssigkeiten zu diagnostischen Zwecken, sowie Immunoassays für die Durchführung einer solchen Bestimmung |
| US8828981B2 (en) | 2007-02-06 | 2014-09-09 | George Creasy | Progesterone for the treatment or prevention of spontaneous preterm birth |
| WO2009070794A1 (en) * | 2007-11-29 | 2009-06-04 | Jackson Gregg A | Progesterone-containing compositions and devices |
| US9107696B2 (en) * | 2008-08-06 | 2015-08-18 | Emory University | Method of embryo transfer that eliminates transferred air while hormonally inducing implantation and apparatus |
| WO2011073995A2 (en) | 2009-12-14 | 2011-06-23 | Lincoln Pharmaceuticals Limited | Liquid vaginal spray of progesterone |
| FR2997627B1 (fr) | 2012-11-08 | 2015-01-16 | Hra Pharma Lab | Produit de co-micronisation comprenant de l'ulipristal acetate |
| CN114129530A (zh) * | 2021-12-08 | 2022-03-04 | 南京康川济医药科技有限公司 | 一种黄体酮缓释组合物及其制备方法 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3121663A (en) | 1956-02-09 | 1964-02-18 | Plough Lab Inc | Carbon dioxide releasing laxative suppository |
| US4252787A (en) * | 1976-12-27 | 1981-02-24 | Cambridge Research And Development Group | Anti-fertility composition and method |
| US4310510A (en) * | 1976-12-27 | 1982-01-12 | Sherman Kenneth N | Self administrable anti-fertility composition |
| US4187286A (en) * | 1979-01-02 | 1980-02-05 | G&W Laboratories, Inc. | Contraceptive suppository |
| US4322399A (en) * | 1979-10-19 | 1982-03-30 | Ortho Pharmaceutical Corporation | Vaginal suppository |
| JPS58152809A (ja) * | 1982-03-05 | 1983-09-10 | Eisai Co Ltd | 安定な発泡性「膣」坐剤 |
| US4583211A (en) * | 1982-06-15 | 1986-04-15 | Tokyo Shibaura Denki Kabushiki Kaisha | Frequency detecting circuit for digital information reproducing system |
| JPS6165822A (ja) * | 1984-09-06 | 1986-04-04 | Kao Corp | 月経困難症治療用膣投与剤 |
| US5116619A (en) * | 1988-08-30 | 1992-05-26 | Lee Roy Morgan | Vaginal progesterone tablet |
| US5084277A (en) * | 1988-08-30 | 1992-01-28 | Greco John C | Vaginal progesterone tablet |
| DK95093D0 (da) * | 1993-08-20 | 1993-08-20 | Novo Nordisk As | Farmaceutisk formulering indeholdende et hormon |
| US5543150A (en) * | 1993-09-15 | 1996-08-06 | Columbia Laboratories, Inc. | Method of progesterone delivery and affect thereof |
| CH689802A5 (de) * | 1995-01-16 | 1999-11-30 | Grapha Holding Ag | Einrichtung zur Vereinzelung von stapelweise zugeführten flachen Gegenständen. |
| US5804277A (en) * | 1995-11-30 | 1998-09-08 | The United States Of America As Represented By The Secretary Of The Air Force | Three-dimensional fiber weave with cubic symmetry and no zero valued shear moduli |
| US5958455A (en) * | 1996-02-09 | 1999-09-28 | Quadrant Holdings Cambridge Ltd | Oral solid dosage forms, methods of making same and compositions thereof |
| US5837861A (en) * | 1997-02-10 | 1998-11-17 | Inspire Pharmaceuticals, Inc. | Dinucleotides and their use as modulators of mucociliary clearance and ciliary beat frequency |
| US6096291A (en) * | 1996-12-27 | 2000-08-01 | Biovector Therapeutics, S.A. | Mucosal administration of substances to mammals |
| US5993856A (en) | 1997-01-24 | 1999-11-30 | Femmepharma | Pharmaceutical preparations and methods for their administration |
| US6306914B1 (en) * | 1997-10-21 | 2001-10-23 | Columbia Laboratories, Inc. | Progestin therapy for maintaining amenorrhea |
| NZ330596A (en) * | 1998-06-05 | 2001-02-23 | Dec Res | Intravaginal devices allowing for increased uptake of active ingredients |
| FR2772617B1 (fr) | 1997-12-19 | 2001-03-09 | Besins Iscovesco Lab | Comprime de progesterone et son procede de preparation |
| FR2777784B1 (fr) * | 1998-04-27 | 2004-03-19 | Arepa | Composition pharmaceutique a base d'estrogene et de progesterone |
| US20070178139A1 (en) * | 1998-11-18 | 2007-08-02 | Yankov Vladimir I | Vaginally administratable progesterone-containing tablets and method for preparing same |
| IL127129A (en) * | 1998-11-18 | 2004-06-01 | Ferring Bv | Method for preparation of progesterone tablets for vaginal delivery and tablets so prepared |
| DE102012021570A1 (de) * | 2012-11-02 | 2014-05-22 | Merck Patent Gmbh | Eu-aktivierte Leuchtstoffe |
-
1998
- 1998-11-18 IL IL12712998A patent/IL127129A/en not_active IP Right Cessation
-
1999
- 1999-11-17 ES ES99972096T patent/ES2390959T3/es not_active Expired - Lifetime
- 1999-11-17 JP JP2000582018A patent/JP4667601B2/ja not_active Expired - Lifetime
- 1999-11-17 EP EP11166346A patent/EP2386291A1/en not_active Ceased
- 1999-11-17 DK DK99972096.4T patent/DK1131052T3/da active
- 1999-11-17 AU AU11762/00A patent/AU1176200A/en not_active Abandoned
- 1999-11-17 US US09/856,417 patent/US7300664B1/en not_active Expired - Lifetime
- 1999-11-17 EP EP99972096A patent/EP1131052B1/en not_active Expired - Lifetime
- 1999-11-17 WO PCT/IL1999/000619 patent/WO2000028970A1/en not_active Ceased
-
2004
- 2004-04-26 US US10/832,742 patent/US7393543B2/en not_active Expired - Lifetime
-
2005
- 2005-01-12 US US11/039,062 patent/US7320800B2/en not_active Expired - Lifetime
-
2006
- 2006-04-20 US US11/408,614 patent/US20060188571A1/en not_active Abandoned
-
2010
- 2010-10-01 JP JP2010223566A patent/JP2011026335A/ja active Pending
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