JP2010539901A - 長鎖散在反復配列ポリペプチド組成物およびその使用方法 - Google Patents

長鎖散在反復配列ポリペプチド組成物およびその使用方法 Download PDF

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JP2010539901A
JP2010539901A JP2010525831A JP2010525831A JP2010539901A JP 2010539901 A JP2010539901 A JP 2010539901A JP 2010525831 A JP2010525831 A JP 2010525831A JP 2010525831 A JP2010525831 A JP 2010525831A JP 2010539901 A JP2010539901 A JP 2010539901A
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subject
polypeptide
cells
individual
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JP2010539901A5 (enExample
Inventor
ニクソン，ドゥグラス
ガリソン，キース
メイクルジョン，ドゥンカン
オストロウスキー，マリオ
ジョーンズ，アール．ブラッドリー
アグロウアル，アシシ
エム． ヘヒト，フレデリック
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University of California
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University of California
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/46—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
JP2010525831A 2007-09-20 2008-09-19 長鎖散在反復配列ポリペプチド組成物およびその使用方法 Pending JP2010539901A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97399307P 2007-09-20 2007-09-20
PCT/US2008/010883 WO2009038756A2 (en) 2007-09-20 2008-09-19 Long interspersed nuclear element polypeptide compositions and methods of use thereof

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JP2010539901A true JP2010539901A (ja) 2010-12-24
JP2010539901A5 JP2010539901A5 (enExample) 2011-10-27

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JP2010525831A Pending JP2010539901A (ja) 2007-09-20 2008-09-19 長鎖散在反復配列ポリペプチド組成物およびその使用方法

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US (1) US20110046042A1 (enExample)
EP (1) EP2200637A4 (enExample)
JP (1) JP2010539901A (enExample)
KR (1) KR20100075483A (enExample)
CN (1) CN101969987A (enExample)
AU (1) AU2008301888A1 (enExample)
BR (1) BRPI0817209A2 (enExample)
CA (1) CA2700115A1 (enExample)
MX (1) MX2010003110A (enExample)
RU (1) RU2010115088A (enExample)
WO (1) WO2009038756A2 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2016159377A1 (ja) * 2015-04-03 2018-02-01 国立大学法人京都大学 がんの治療薬のスクリーニング方法
JP2021168652A (ja) * 2015-04-24 2021-10-28 イマティクス バイオテクノロジーズ ゲーエムベーハー Ｎｓｃｌｃをはじめとする肺がんおよびその他のがんに対する免疫療法において使用するための新規ペプチドおよびペプチド組み合わせ
JP7569054B2 (ja) 2020-06-02 2024-10-17 学校法人東京女子医科大学 Ｓ１００ａ８阻害ペプチドとこれを含む疾患治療薬

Families Citing this family (9)

* Cited by examiner, † Cited by third party
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US8168181B2 (en) 2006-02-13 2012-05-01 Alethia Biotherapeutics, Inc. Methods of impairing osteoclast differentiation using antibodies that bind siglec-15
CA2638823A1 (en) 2006-02-13 2007-08-23 Alethia Biotherapeutics Inc. Polynucleotides and polypeptide sequences involved in the process of bone remodeling
US8647640B2 (en) 2009-06-24 2014-02-11 Richard E. COWART Vaccine compositions and methods of use to protect against infectious disease
US20140031250A1 (en) * 2010-10-07 2014-01-30 David Tsai Ting Biomarkers of Cancer
WO2014004945A1 (en) * 2012-06-28 2014-01-03 University Of Louisville Research Foundation, Inc. Use of protein line-1 orf-1 as a biomarker for cancer
ES2723885T3 (es) 2012-07-19 2019-09-03 Daiichi Sankyo Co Ltd Anticuerpos anti-Siglec-15
EP3760208B1 (en) 2014-06-25 2024-05-29 The General Hospital Corporation Targeting human satellite ii (hsatii)
CA3154827A1 (en) * 2019-10-16 2021-04-22 Valerio Orlando Methods for modulating human l1 retrotransposons rna and compositions for use therein
EP4081309A4 (en) * 2019-12-26 2024-01-17 The Johns Hopkins University ENHANCED LINE-1 ENCODED ORF2P EXPRESSION FOR CANCER THERAPEUTIC AGENTS

Citations (3)

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WO2001073068A1 (fr) * 2000-03-27 2001-10-04 Shanghai Biowindow Gene Development Inc. Nouveau polypeptide, l1-12, et polynucleotide codant pour ce polypeptide
WO2004039952A2 (en) * 2002-10-25 2004-05-13 Five Prime Therapeutics, Inc. Methods of use for novel human polypeptides encoded by polynucleotides
US20070010469A1 (en) * 2000-06-02 2007-01-11 Chan Vivien W Gene products differentially expressed in cancerous cells III

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US5280108A (en) * 1991-09-27 1994-01-18 United States Of America Antibodies to p40
ES2309992T3 (es) * 1995-10-20 2008-12-16 University Of Nebraska Board Of Regents Composiciones y procedimientos para incrementar las respuestas inmunes mediadas por celulas presentadoras de antigeno.
CN1315379A (zh) * 2000-03-27 2001-10-03 上海博德基因开发有限公司 一种新的多肽——人L1因子p40蛋白12和编码这种多肽的多核苷酸
US6436703B1 (en) * 2000-03-31 2002-08-20 Hyseq, Inc. Nucleic acids and polypeptides
CN1339478A (zh) * 2000-08-21 2002-03-13 上海博德基因开发有限公司 一种新的多肽——人l1因子orf2相关蛋白10.78和编码这种多肽的多核苷酸
CN1339450A (zh) * 2000-08-21 2002-03-13 上海博德基因开发有限公司 一种新的多肽——转座元蛋白14.41和编码这种多肽的多核苷酸
CN1343776A (zh) * 2000-09-19 2002-04-10 上海博德基因开发有限公司 一种新的多肽——dna聚合酶9.02和编码这种多肽的多核苷酸
CN1352094A (zh) * 2000-11-06 2002-06-05 上海博德基因开发有限公司 一种新的多肽——人l1元件类蛋白19.80和编码这种多肽的多核苷酸
CN1425684A (zh) * 2001-12-19 2003-06-25 复旦大学 一种多肽——人反转录转座40蛋白－12.76和编码这种多肽的多核苷酸
EP1609107A4 (en) * 2003-03-28 2006-08-30 Idm Pharma Inc METHOD FOR IDENTIFYING OPTIMAL PEPTIDE PITOPARIANTS
WO2005049789A2 (en) * 2003-05-28 2005-06-02 The Johns Hopkins University Synthetic mammalian retrotransposon gene

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001073068A1 (fr) * 2000-03-27 2001-10-04 Shanghai Biowindow Gene Development Inc. Nouveau polypeptide, l1-12, et polynucleotide codant pour ce polypeptide
US20070010469A1 (en) * 2000-06-02 2007-01-11 Chan Vivien W Gene products differentially expressed in cancerous cells III
WO2004039952A2 (en) * 2002-10-25 2004-05-13 Five Prime Therapeutics, Inc. Methods of use for novel human polypeptides encoded by polynucleotides

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2016159377A1 (ja) * 2015-04-03 2018-02-01 国立大学法人京都大学 がんの治療薬のスクリーニング方法
JP2021168652A (ja) * 2015-04-24 2021-10-28 イマティクス バイオテクノロジーズ ゲーエムベーハー Ｎｓｃｌｃをはじめとする肺がんおよびその他のがんに対する免疫療法において使用するための新規ペプチドおよびペプチド組み合わせ
JP7525442B2 (ja) 2015-04-24 2024-07-30 イマティクス バイオテクノロジーズ ゲーエムベーハー Ｎｓｃｌｃをはじめとする肺がんおよびその他のがんに対する免疫療法において使用するための新規ペプチドおよびペプチド組み合わせ
JP7569054B2 (ja) 2020-06-02 2024-10-17 学校法人東京女子医科大学 Ｓ１００ａ８阻害ペプチドとこれを含む疾患治療薬

Also Published As

Publication number Publication date
WO2009038756A3 (en) 2009-05-14
EP2200637A4 (en) 2011-10-19
CN101969987A (zh) 2011-02-09
CA2700115A1 (en) 2009-03-26
US20110046042A1 (en) 2011-02-24
BRPI0817209A2 (pt) 2015-03-10
WO2009038756A2 (en) 2009-03-26
RU2010115088A (ru) 2011-10-27
MX2010003110A (es) 2010-05-19
EP2200637A2 (en) 2010-06-30
KR20100075483A (ko) 2010-07-02
AU2008301888A1 (en) 2009-03-26

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