JP2010537623A5 - - Google Patents
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- Publication number
- JP2010537623A5 JP2010537623A5 JP2010500022A JP2010500022A JP2010537623A5 JP 2010537623 A5 JP2010537623 A5 JP 2010537623A5 JP 2010500022 A JP2010500022 A JP 2010500022A JP 2010500022 A JP2010500022 A JP 2010500022A JP 2010537623 A5 JP2010537623 A5 JP 2010537623A5
- Authority
- JP
- Japan
- Prior art keywords
- androgen
- polypeptide
- binding
- polypeptide according
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003098 androgen Substances 0.000 claims 10
- 229920001184 polypeptide Polymers 0.000 claims 9
- 102000004196 processed proteins & peptides Human genes 0.000 claims 9
- 108090000765 processed proteins & peptides Proteins 0.000 claims 9
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 claims 2
- 101000775732 Homo sapiens Androgen receptor Proteins 0.000 claims 1
- 101000928259 Homo sapiens NADPH:adrenodoxin oxidoreductase, mitochondrial Proteins 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 102000034755 Sex Hormone-Binding Globulin Human genes 0.000 claims 1
- 108010089417 Sex Hormone-Binding Globulin Proteins 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 102000046818 human AR Human genes 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 229960003604 testosterone Drugs 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2007901628A AU2007901628A0 (en) | 2007-03-27 | Methods and compositions for treating prostate cancer | |
| US94528207P | 2007-06-20 | 2007-06-20 | |
| US99063707P | 2007-11-28 | 2007-11-28 | |
| PCT/AU2008/000424 WO2008116262A1 (en) | 2007-03-27 | 2008-03-26 | Methods and compositions for treating prostate cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010537623A JP2010537623A (ja) | 2010-12-09 |
| JP2010537623A5 true JP2010537623A5 (enExample) | 2011-05-12 |
Family
ID=39787967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010500022A Pending JP2010537623A (ja) | 2007-03-27 | 2008-03-26 | 前立腺癌を治療する方法及び組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20100092477A1 (enExample) |
| EP (1) | EP2137213A4 (enExample) |
| JP (1) | JP2010537623A (enExample) |
| AU (1) | AU2008232311A1 (enExample) |
| CA (1) | CA2681917A1 (enExample) |
| WO (1) | WO2008116262A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009033212A1 (en) * | 2007-09-11 | 2009-03-19 | Christopher Hovens | The use of estrogen and androgen binding proteins in methods and compositions for treating gynaecological cancers |
| US20110144032A1 (en) * | 2008-08-08 | 2011-06-16 | Christopher Hovens | Biological applications of steroid binding domains |
| CA2786535C (en) | 2010-01-11 | 2019-03-26 | Curna, Inc. | Treatment of sex hormone binding globulin (shbg) related diseases by inhibition of natural antisense transcript to shbg |
| KR101183615B1 (ko) * | 2011-12-28 | 2012-09-17 | 재단법인 경기과학기술진흥원 | Ｗｎｔ에 결합하는 신규한 재조합 단백질 |
| WO2014152640A1 (en) * | 2013-03-15 | 2014-09-25 | Invivis Pharmaceuticals Inc. | Assay for predictive biomarkers of anti-androgen efficacy |
| WO2016184829A1 (en) * | 2015-05-18 | 2016-11-24 | Nerre Therapeutics Limited | Dual nk-1/nk-3 receptor antagonists for the treatment of sex-hormone-dependent diseases |
| CN120605334B (zh) * | 2025-08-11 | 2025-11-04 | 核工业总医院 | Fbxo2在治疗前列腺癌中的应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6307030B1 (en) * | 1988-04-15 | 2001-10-23 | The University Of North Carolina At Chapel Hill | Androgen receptor proteins, recombinant DNA molecules coding for such, and use of such compositions |
| JPH04356427A (ja) * | 1991-02-26 | 1992-12-10 | Keisuke Hirasawa | 免疫賦活剤 |
| GB9809951D0 (en) * | 1998-05-08 | 1998-07-08 | Univ Cambridge Tech | Binding molecules |
| US6117639A (en) * | 1998-08-31 | 2000-09-12 | Vertex Pharmaceuticals Incorporated | Fusion proteins, DNA molecules, vectors, and host cells useful for measuring protease activity |
| DK1436003T3 (da) * | 2001-05-24 | 2010-03-15 | Zymogenetics Inc | TACI-immunoglobulin-fusionsproteiner |
| EP1673395A1 (en) * | 2003-10-15 | 2006-06-28 | PDL BioPharma, Inc. | Alteration of fc-fusion protein serum half-lives by mutagenesis of positions 250, 314 and/or 428 of the heavy chain constant region of ig |
| US20060246511A1 (en) * | 2005-04-27 | 2006-11-02 | B&C Biotech | Methods of determining levels of steroid fractions utilizing SHBG calculations |
| GB0614568D0 (en) * | 2006-07-21 | 2006-08-30 | Haptogen Ltd | Anti-testosterone antibodies |
-
2008
- 2008-03-26 CA CA002681917A patent/CA2681917A1/en not_active Abandoned
- 2008-03-26 JP JP2010500022A patent/JP2010537623A/ja active Pending
- 2008-03-26 WO PCT/AU2008/000424 patent/WO2008116262A1/en not_active Ceased
- 2008-03-26 AU AU2008232311A patent/AU2008232311A1/en not_active Abandoned
- 2008-03-26 EP EP08733272A patent/EP2137213A4/en not_active Withdrawn
-
2009
- 2009-09-28 US US12/568,590 patent/US20100092477A1/en not_active Abandoned
-
2012
- 2012-08-13 US US13/584,263 patent/US20130064821A1/en not_active Abandoned
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