JP2010536738A - 薬剤の組み合わせの送達 - Google Patents

薬剤の組み合わせの送達 Download PDF

Info

Publication number
JP2010536738A
JP2010536738A JP2010520637A JP2010520637A JP2010536738A JP 2010536738 A JP2010536738 A JP 2010536738A JP 2010520637 A JP2010520637 A JP 2010520637A JP 2010520637 A JP2010520637 A JP 2010520637A JP 2010536738 A JP2010536738 A JP 2010536738A
Authority
JP
Japan
Prior art keywords
drug
polymer
water
group
matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010520637A
Other languages
English (en)
Japanese (ja)
Inventor
レナード ルイス,アンドリュー
フォスター,リチャード,エドワード,ジョン
ヴィクトリア ゴンザレス−ファヤルド,マリア
タン,イチン
ウィリアム ロイド,アンドリュー
フィリップス,ゲイリー,ジェイムズ
Original Assignee
バイオコンパティブルズ ユーケー リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0716003A external-priority patent/GB0716003D0/en
Application filed by バイオコンパティブルズ ユーケー リミテッド filed Critical バイオコンパティブルズ ユーケー リミテッド
Publication of JP2010536738A publication Critical patent/JP2010536738A/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2010520637A 2007-08-16 2008-08-18 薬剤の組み合わせの送達 Pending JP2010536738A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0716003A GB0716003D0 (en) 2007-08-16 2007-08-16 Delivery of drug combinations
EP07121158 2007-11-20
PCT/GB2008/050722 WO2009022190A1 (en) 2007-08-16 2008-08-18 Delivery of drug combinations

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014016185A Division JP2014114307A (ja) 2007-08-16 2014-01-30 薬剤の組み合わせの送達

Publications (1)

Publication Number Publication Date
JP2010536738A true JP2010536738A (ja) 2010-12-02

Family

ID=39941549

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2010520637A Pending JP2010536738A (ja) 2007-08-16 2008-08-18 薬剤の組み合わせの送達
JP2014016185A Pending JP2014114307A (ja) 2007-08-16 2014-01-30 薬剤の組み合わせの送達
JP2016114725A Pending JP2016216465A (ja) 2007-08-16 2016-06-08 薬剤の組み合わせの送達

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2014016185A Pending JP2014114307A (ja) 2007-08-16 2014-01-30 薬剤の組み合わせの送達
JP2016114725A Pending JP2016216465A (ja) 2007-08-16 2016-06-08 薬剤の組み合わせの送達

Country Status (6)

Country Link
US (1) US20110229572A1 (enExample)
EP (1) EP2190409B9 (enExample)
JP (3) JP2010536738A (enExample)
ES (1) ES2706023T3 (enExample)
TR (1) TR201820076T4 (enExample)
WO (1) WO2009022190A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014534219A (ja) * 2011-10-25 2014-12-18 ネクター セラピューティクス 癌患者の治療
JP2017513460A (ja) * 2014-03-06 2017-06-01 ユニヴァーシティ オブ サザン カリフォルニアUniversity of Southern California 従来の化学療法剤の効力および実行可能性を増強し、かつ正常な細胞および組織におけるキナーゼの副作用を逆転させるための、キナーゼ阻害剤と併用した短期間絶食レジメンの使用

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1985286A1 (en) * 2007-04-24 2008-10-29 Biocompatibles UK Limited Microspheres for treatment of brain tumours
US20200397766A1 (en) * 2018-02-23 2020-12-24 Van Rijn Beheer B.V. Porous embolization microspheres comprising drugs
WO2020077170A1 (en) 2018-10-12 2020-04-16 University Of Pittsburgh- Of The Commonwealth System Of Higher Education Small polymeric carriers for delivery of agents
CN110327300B (zh) * 2019-07-23 2020-08-07 赵修文 一种负载药物的聚乙烯醇微球
WO2022010850A1 (en) * 2020-07-06 2022-01-13 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Polymeric carriers for delivery of therapeutic agents
WO2022047544A1 (en) * 2020-09-04 2022-03-10 IP Cornerstone Pty Ltd Minimally invasive treatment of osteoarthritis and other conditions
CN117677388A (zh) * 2021-05-12 2024-03-08 润新生物公司 某些化学实体、组合物和方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005508920A (ja) * 2001-10-03 2005-04-07 セレーター テクノロジーズ インコーポレイテッド 併用薬剤を送達するための組成物
WO2006027567A2 (en) * 2004-09-07 2006-03-16 Biocompatibles Uk Limited Drug delivery from embolic agents
JP2006515358A (ja) * 2003-02-12 2006-05-25 バイオコンパティブルズ ユーケー リミテッド 固形腫瘍の化学的塞栓療法用組成物
JP2006522026A (ja) * 2003-04-02 2006-09-28 セレーター ファーマスーティカルズ、インク. カンプトセシンとフルオロピリミジンとを組み合わせた組成物
JP2006523713A (ja) * 2003-04-16 2006-10-19 セレーター ファーマスーティカルズ、インク. 薬剤併用物送達用組成物
WO2007016405A2 (en) * 2005-07-29 2007-02-08 Surmodics, Inc. Devices, articles, coatings, and methods for controlled active agent release or hemocompatibility

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2762140B1 (en) * 2001-02-19 2017-03-22 Novartis AG Treatment of solid brain tumours with a rapamycin derivative
US20050220880A1 (en) * 2002-03-07 2005-10-06 Lewis Andrew L Drug carriers comprising amphiphilic block copolymers
US20040161466A1 (en) * 2003-02-14 2004-08-19 Biocompatibles Uk Limited Chemoembolisation

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005508920A (ja) * 2001-10-03 2005-04-07 セレーター テクノロジーズ インコーポレイテッド 併用薬剤を送達するための組成物
JP2006515358A (ja) * 2003-02-12 2006-05-25 バイオコンパティブルズ ユーケー リミテッド 固形腫瘍の化学的塞栓療法用組成物
JP2006522026A (ja) * 2003-04-02 2006-09-28 セレーター ファーマスーティカルズ、インク. カンプトセシンとフルオロピリミジンとを組み合わせた組成物
JP2006523713A (ja) * 2003-04-16 2006-10-19 セレーター ファーマスーティカルズ、インク. 薬剤併用物送達用組成物
WO2006027567A2 (en) * 2004-09-07 2006-03-16 Biocompatibles Uk Limited Drug delivery from embolic agents
WO2007016405A2 (en) * 2005-07-29 2007-02-08 Surmodics, Inc. Devices, articles, coatings, and methods for controlled active agent release or hemocompatibility

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN6012066475; Journal of Pharmaceutical sciences Vol.93, No.8, 2004, pp.1993-2008 *
JPN7012005219; Expert Opinion on Drug Delivery Vol.3, No.2, 2006, pp.205-216 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014534219A (ja) * 2011-10-25 2014-12-18 ネクター セラピューティクス 癌患者の治療
JP2017513460A (ja) * 2014-03-06 2017-06-01 ユニヴァーシティ オブ サザン カリフォルニアUniversity of Southern California 従来の化学療法剤の効力および実行可能性を増強し、かつ正常な細胞および組織におけるキナーゼの副作用を逆転させるための、キナーゼ阻害剤と併用した短期間絶食レジメンの使用
JP2021020926A (ja) * 2014-03-06 2021-02-18 ユニヴァーシティ オブ サザン カリフォルニアUniversity of Southern California 従来の化学療法剤の効力および実行可能性を増強し、かつ正常な細胞および組織におけるキナーゼの副作用を逆転させるための、キナーゼ阻害剤と併用した短期間絶食レジメンの使用
JP7038432B2 (ja) 2014-03-06 2022-03-18 ユニヴァーシティ オブ サザン カリフォルニア 従来の化学療法剤の効力および実行可能性を増強し、かつ正常な細胞および組織におけるキナーゼの副作用を逆転させるための、キナーゼ阻害剤と併用した短期間絶食レジメンの使用

Also Published As

Publication number Publication date
US20110229572A1 (en) 2011-09-22
WO2009022190A1 (en) 2009-02-19
TR201820076T4 (tr) 2019-01-21
JP2016216465A (ja) 2016-12-22
ES2706023T3 (es) 2019-03-27
JP2014114307A (ja) 2014-06-26
EP2190409B1 (en) 2018-10-24
EP2190409B9 (en) 2019-03-06
EP2190409A1 (en) 2010-06-02

Similar Documents

Publication Publication Date Title
JP2016216465A (ja) 薬剤の組み合わせの送達
JP5221134B2 (ja) 塞栓剤からの薬物送達
US8586098B2 (en) Loading of hydrophobic drugs into hydrophilic polymer delivery systems
Grant et al. Hybrid films from blends of chitosan and egg phosphatidylcholine for localized delivery of paclitaxel
TWI841481B (zh) 乳酸鈣組成物及使用方法
JP5960751B2 (ja) 膵がんの治療
JP2010524981A (ja) 脳腫瘍の治療のための微小球
Doddapaneni et al. A three-drug nanoscale drug delivery system designed for preferential lymphatic uptake for the treatment of metastatic melanoma
CN116173284B (zh) 栓塞微球
US12396951B2 (en) Prevention of local tumor recurrence following surgery using sustainedand/or delayed release of medicaments contained in micro-particles
WO2010072109A1 (zh) 一种肿瘤治疗药物的缓释体系
TW201720447A (zh) 裝載活性成份之奈米粒子、彼等之製法及用途
EP3307264A1 (en) Multi-drug combinations that act as potent radiosensitizers
Altintas et al. Targeted delivery of kinase inhibitors: a nanomedicine approach for improved selectivity in cancer
Wong A study of nanoparticle drug carrier for treatment of multidrug-resistant breast cancer with loco-regional involvement.
HK1163524B (en) Pancreatic tumour treatment

Legal Events

Date Code Title Description
A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20121122

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20121225

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20130325

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20130401

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130625

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130730

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20131030

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20131107

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20131129

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20131206

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20131225

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20140108

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140130

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20140507