JP2010536386A5 - - Google Patents

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Publication number
JP2010536386A5
JP2010536386A5 JP2010522105A JP2010522105A JP2010536386A5 JP 2010536386 A5 JP2010536386 A5 JP 2010536386A5 JP 2010522105 A JP2010522105 A JP 2010522105A JP 2010522105 A JP2010522105 A JP 2010522105A JP 2010536386 A5 JP2010536386 A5 JP 2010536386A5
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JP
Japan
Prior art keywords
cancer
receptor
item
arginine
targeting reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010522105A
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English (en)
Japanese (ja)
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JP2010536386A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/074268 external-priority patent/WO2009029601A2/en
Publication of JP2010536386A publication Critical patent/JP2010536386A/ja
Publication of JP2010536386A5 publication Critical patent/JP2010536386A5/ja
Pending legal-status Critical Current

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JP2010522105A 2007-08-24 2008-08-25 受容体標的化試薬 Pending JP2010536386A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95793607P 2007-08-24 2007-08-24
PCT/US2008/074268 WO2009029601A2 (en) 2007-08-24 2008-08-25 Receptor-targeting reagents

Publications (2)

Publication Number Publication Date
JP2010536386A JP2010536386A (ja) 2010-12-02
JP2010536386A5 true JP2010536386A5 (https=) 2011-10-06

Family

ID=40388106

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010522105A Pending JP2010536386A (ja) 2007-08-24 2008-08-25 受容体標的化試薬

Country Status (5)

Country Link
US (2) US9155798B2 (https=)
EP (1) EP2197909A4 (https=)
JP (1) JP2010536386A (https=)
CA (1) CA2697529A1 (https=)
WO (1) WO2009029601A2 (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010229924B2 (en) 2009-03-24 2016-07-21 Plus Therapeutics Inc. Devices and methods of cell capture and analysis
US20120100538A1 (en) 2009-03-24 2012-04-26 Biocept, Inc. Devices and methods of cell capture and analysis
DK2462449T3 (en) * 2009-08-03 2017-01-09 Yeda Res & Dev Urinary biomarkers for cancer diagnosis
WO2012027494A1 (en) * 2010-08-24 2012-03-01 Regents Of The University Of Minnesota Bispecific targeting reagents
EP2670426B1 (en) 2011-01-31 2017-05-10 The General Hospital Corporation Multimodal trail molecules and uses in cellular therapies
EP2850093B1 (en) 2012-01-27 2019-01-09 The Board of Trustees of the Leland Stanford Junior University Therapeutic il-13 polypeptides
EP2877572B1 (en) 2012-07-24 2018-11-28 The General Hospital Corporation Oncolytic virus therapy for resistant tumors
IN2015KN00329A (https=) 2012-08-09 2015-07-10 Univ Leland Stanford Junior
WO2014035474A1 (en) 2012-08-30 2014-03-06 The General Hospital Corporation Compositions and methods for treating cancer
CN103865899B (zh) * 2012-12-17 2016-04-27 山西康宝生物制品股份有限公司 具有vegfr2/kdr受体特异性的融合毒素及其编码基因与应用
WO2015042705A1 (en) * 2013-09-24 2015-04-02 Medicenna Biopharma Inc. Interleukin-4 receptor-binding fusion proteins and uses thereof
US20170209579A1 (en) * 2014-07-24 2017-07-27 Baylor College Of Medicine Non-invasive radiofrequency field treatment for cancer therapy
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
MX389194B (es) * 2015-10-06 2025-03-20 Univ Minnesota Compuestos terapéuticos y métodos.
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
WO2019073299A1 (en) 2017-10-10 2019-04-18 Medicenna Therapeutics, Inc. IL-4 FUSION FORMULATIONS FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM (CNS) TUMORS
WO2019232523A1 (en) 2018-06-01 2019-12-05 The Board Of Trustees Of The Leland Stanford Junior University Il-13/il-4 superkines: immune cell targeting constructs and methods of use thereof
WO2019239213A2 (en) 2018-06-01 2019-12-19 Medicenna Therapeutics Inc. Uses and methods for oncolytic virus targeting of il-4/il-13 and fusions thereof
WO2020033398A1 (en) * 2018-08-06 2020-02-13 The Trustees Of Columbia University In The City Of New York Compositions and methods for treating atii cell-dependent lung diseases
WO2020081841A1 (en) 2018-10-19 2020-04-23 Regents Of The University Of Minnesota Nk engager molecules and methods of use thereof
WO2020219599A1 (en) * 2019-04-23 2020-10-29 Aurora Oncology Compositions and methods for treatment of distentable tissues
EP4269447A4 (en) * 2020-12-22 2024-07-24 Jiangsu Hengrui Pharmaceuticals Co., Ltd. ANTI-IL-4R ANTIBODY COMPLEX OR ANTIGEN-BINDING FRAGMENT THEREOF AND ASSOCIATED MEDICAL USE
WO2022246052A1 (en) * 2021-05-19 2022-11-24 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Il-13ralpha2 targeted immunotoxins and methods of use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US142539A (en) * 1873-09-02 Improvement
AU6769998A (en) * 1997-03-26 1998-10-20 Board Of Regents, The University Of Texas System Methods and compositions for using membrane-penetrating proteins to carry materials across cell membranes
US6034053A (en) 1998-07-13 2000-03-07 Wayne Hughes Institute EGF-isoflavone conjugates for the prevention of restenosis
DE19839671C2 (de) * 1998-09-01 2000-08-03 Forschungszentrum Juelich Gmbh Sensor zur Messung eines Magnetfeldes
US6864359B1 (en) * 1999-02-11 2005-03-08 Xencor Structure-based screening techniques for drug discovery
US20050142539A1 (en) 2002-01-14 2005-06-30 William Herman Targeted ligands
WO2004096254A2 (en) 2003-05-02 2004-11-11 Xpression Antibody Therapeutics, Inc. Transferrin conjugates for tumor treatment

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