JP2010535811A5 - - Google Patents

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Publication number
JP2010535811A5
JP2010535811A5 JP2010520313A JP2010520313A JP2010535811A5 JP 2010535811 A5 JP2010535811 A5 JP 2010535811A5 JP 2010520313 A JP2010520313 A JP 2010520313A JP 2010520313 A JP2010520313 A JP 2010520313A JP 2010535811 A5 JP2010535811 A5 JP 2010535811A5
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JP
Japan
Prior art keywords
conjugate
cancer
agent
composition
moiety
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2010520313A
Other languages
English (en)
Japanese (ja)
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JP2010535811A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/072524 external-priority patent/WO2009021136A1/en
Publication of JP2010535811A publication Critical patent/JP2010535811A/ja
Publication of JP2010535811A5 publication Critical patent/JP2010535811A5/ja
Withdrawn legal-status Critical Current

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JP2010520313A 2007-08-07 2008-08-07 薬物キャリアとしてのクロロトキシン Withdrawn JP2010535811A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95440907P 2007-08-07 2007-08-07
PCT/US2008/072524 WO2009021136A1 (en) 2007-08-07 2008-08-07 Chlorotoxins as drug carriers

Publications (2)

Publication Number Publication Date
JP2010535811A JP2010535811A (ja) 2010-11-25
JP2010535811A5 true JP2010535811A5 (OSRAM) 2011-09-22

Family

ID=40341745

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010520313A Withdrawn JP2010535811A (ja) 2007-08-07 2008-08-07 薬物キャリアとしてのクロロトキシン

Country Status (6)

Country Link
US (1) US20110091380A1 (OSRAM)
EP (1) EP2173385A1 (OSRAM)
JP (1) JP2010535811A (OSRAM)
AU (1) AU2008285364A1 (OSRAM)
CA (1) CA2696303A1 (OSRAM)
WO (1) WO2009021136A1 (OSRAM)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602006020710D1 (de) * 2005-04-22 2011-04-28 Fred Hutchinson Cancer Res Foundation Fluoreszentes chlorotoxinkonjugat und verfahren zur intraoperativen sichtbarmachung von krebs
CA2724384A1 (en) 2008-05-15 2009-11-19 Transmolecular, Inc. Treatment of metastatic tumors
HRP20171291T1 (hr) 2010-02-04 2017-10-20 Morphotek, Inc. Polipeptidi i konjugati klorotoksina i njihove uporabe
WO2011126010A1 (ja) * 2010-04-06 2011-10-13 三菱化学株式会社 癌細胞選択的膜透過性ペプチドおよびその利用
CN103097403B (zh) 2010-05-11 2017-04-19 弗雷德哈钦森癌症研究中心 氯毒素变体、缀合物及其使用方法
WO2013003507A1 (en) 2011-06-27 2013-01-03 Morphotek, Inc. Multifunctional agents
CA2913127A1 (en) 2012-12-10 2014-06-19 Fred Hutchinson Cancer Research Center Methods for screening
US11559580B1 (en) 2013-09-17 2023-01-24 Blaze Bioscience, Inc. Tissue-homing peptide conjugates and methods of use thereof
CA3021011A1 (en) 2016-04-15 2017-10-19 Blaze Bioscience, Inc. Methods of treating breast cancer
CN110352197B (zh) * 2016-12-09 2024-02-02 Uab研究基金会 嵌合氯毒素受体
CN111542345B (zh) 2017-09-15 2025-02-25 卫材公司 氯毒素剂及其用途
CA3086040A1 (en) 2017-12-19 2019-06-27 Blaze Bioscience, Inc. Tumor homing and cell penetrating peptide-immuno-oncology agent complexes and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6667156B2 (en) * 1995-12-27 2003-12-23 Uab Research Foundation Diagnosis and treatment of neuroectodermal tumors
US5905027A (en) * 1995-12-27 1999-05-18 Uab Research Foundation Method of diagnosing and treating gliomas
JP2005537234A (ja) * 2002-05-31 2005-12-08 トランスモルキュラー インコーポレイテッド クロロトキシンとの併用化学療法
US20060088899A1 (en) * 2002-05-31 2006-04-27 Alvarez Vernon L Combination chemotherapy with chlorotoxin
US7638299B2 (en) * 2004-07-21 2009-12-29 Ambrx, Inc. Biosynthetic polypeptides utilizing non-naturally encoded amino acids
DE602006020710D1 (de) * 2005-04-22 2011-04-28 Fred Hutchinson Cancer Res Foundation Fluoreszentes chlorotoxinkonjugat und verfahren zur intraoperativen sichtbarmachung von krebs

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