JP2010535713A5 - - Google Patents

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Publication number
JP2010535713A5
JP2010535713A5 JP2010519276A JP2010519276A JP2010535713A5 JP 2010535713 A5 JP2010535713 A5 JP 2010535713A5 JP 2010519276 A JP2010519276 A JP 2010519276A JP 2010519276 A JP2010519276 A JP 2010519276A JP 2010535713 A5 JP2010535713 A5 JP 2010535713A5
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JP
Japan
Prior art keywords
seq
antibody
region
antigen
binding fragment
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Application number
JP2010519276A
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English (en)
Japanese (ja)
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JP2010535713A (ja
JP5409628B2 (ja
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Priority claimed from PCT/US2008/072146 external-priority patent/WO2009020933A2/en
Publication of JP2010535713A publication Critical patent/JP2010535713A/ja
Publication of JP2010535713A5 publication Critical patent/JP2010535713A5/ja
Application granted granted Critical
Publication of JP5409628B2 publication Critical patent/JP5409628B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2010519276A 2007-08-03 2008-08-04 抗ｔｗｅａｋ受容体抗体の治療上の使用 Expired - Fee Related JP5409628B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US95374507P 2007-08-03 2007-08-03
US60/953,745 2007-08-03
US12362308P 2008-04-09 2008-04-09
US61/123,623 2008-04-09
PCT/US2008/072146 WO2009020933A2 (en) 2007-08-03 2008-08-04 Therapeutic use of anti-tweak receptor antibodies

Publications (3)

Publication Number Publication Date
JP2010535713A JP2010535713A (ja) 2010-11-25
JP2010535713A5 true JP2010535713A5 (Direct) 2011-09-22
JP5409628B2 JP5409628B2 (ja) 2014-02-05

Family

ID=40193427

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010519276A Expired - Fee Related JP5409628B2 (ja) 2007-08-03 2008-08-04 抗ｔｗｅａｋ受容体抗体の治療上の使用

Country Status (12)

Country Link
US (1) US9056908B2 (Direct)
EP (2) EP2182982B1 (Direct)
JP (1) JP5409628B2 (Direct)
KR (1) KR20100053607A (Direct)
CN (1) CN102006886A (Direct)
BR (1) BRPI0814768A2 (Direct)
CA (1) CA2694751C (Direct)
ES (1) ES2411907T3 (Direct)
IL (1) IL203038A (Direct)
MX (1) MX2010001378A (Direct)
NZ (1) NZ582815A (Direct)
WO (1) WO2009020933A2 (Direct)

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EP3313521A1 (de) 2015-06-23 2018-05-02 Bayer Pharma Aktiengesellschaft Antikörper-wirkstoff-konjugate (adcs) von ksp-inhibitoren mit anti-tweakr-antikörpern
US11071788B2 (en) 2015-06-23 2021-07-27 Bayer Pharma Aktiengesellschaft Antibody drug conjugates of kinesin spindel protein (KSP) inhibitors with antiB7H3-antibodies
AU2016282724A1 (en) * 2015-06-23 2018-01-18 Bayer Pharma Aktiengesellschaft Targeted conjugates of KSP inhibitors
WO2017060322A2 (en) 2015-10-10 2017-04-13 Bayer Pharma Aktiengesellschaft Ptefb-inhibitor-adc
CA3018630A1 (en) 2016-03-24 2017-09-28 Bayer Pharma Aktiengesellschaft Prodrugs of cytotoxic active agents having enzymatically cleavable groups
EP3919518A1 (en) 2016-06-15 2021-12-08 Bayer Pharma Aktiengesellschaft Specific antibody-drug-conjugates (adcs) with ksp inhibitors and anti-cd123-antibodies
RU2761390C2 (ru) 2016-12-21 2021-12-07 Байер Фарма Акциенгезельшафт Конъюгаты связующего и активного вещества (adc), имеющие ферментативно расщепляемые группы
JP7174704B2 (ja) 2016-12-21 2022-11-17 バイエル・アクチエンゲゼルシヤフト 酵素開裂基を有する細胞毒性活性剤のプロドラッグ
CN110072556B (zh) 2016-12-21 2023-05-02 拜耳制药股份公司 具有ksp抑制剂的特异性抗体药物缀合物(adc)
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