JP2010535486A5 - - Google Patents

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Publication number
JP2010535486A5
JP2010535486A5 JP2010519503A JP2010519503A JP2010535486A5 JP 2010535486 A5 JP2010535486 A5 JP 2010535486A5 JP 2010519503 A JP2010519503 A JP 2010519503A JP 2010519503 A JP2010519503 A JP 2010519503A JP 2010535486 A5 JP2010535486 A5 JP 2010535486A5
Authority
JP
Japan
Prior art keywords
seq
leptin
polypeptide
nucleic acid
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2010519503A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010535486A (ja
Filing date
Publication date
Priority claimed from GBGB0715216.8A external-priority patent/GB0715216D0/en
Application filed filed Critical
Publication of JP2010535486A publication Critical patent/JP2010535486A/ja
Publication of JP2010535486A5 publication Critical patent/JP2010535486A5/ja
Withdrawn legal-status Critical Current

Links

JP2010519503A 2007-08-03 2008-07-23 レプチン融合タンパク質 Withdrawn JP2010535486A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0715216.8A GB0715216D0 (en) 2007-08-03 2007-08-03 Leptin
US95636007P 2007-08-16 2007-08-16
PCT/GB2008/002489 WO2009019427A1 (en) 2007-08-03 2008-07-23 Leptin fusion proteins

Publications (2)

Publication Number Publication Date
JP2010535486A JP2010535486A (ja) 2010-11-25
JP2010535486A5 true JP2010535486A5 (enExample) 2011-09-15

Family

ID=38529304

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010519503A Withdrawn JP2010535486A (ja) 2007-08-03 2008-07-23 レプチン融合タンパク質

Country Status (6)

Country Link
US (1) US20110092417A1 (enExample)
EP (1) EP2185585A1 (enExample)
JP (1) JP2010535486A (enExample)
CN (1) CN101827858A (enExample)
GB (1) GB0715216D0 (enExample)
WO (1) WO2009019427A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX349054B (es) 2010-09-28 2017-07-07 Aegerion Pharmaceuticals Inc Leptinas altamente solubles.
DK2729160T3 (da) * 2011-07-08 2019-07-01 Aegerion Pharmaceuticals Inc Manipulerede polypeptider, der har forbedret virkningstid og reduceret immunogenicitet
JP6006309B2 (ja) 2011-07-08 2016-10-12 アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc 作用持続期間が増大し、免疫原性が減少した操作されたポリペプチド
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
TWI824372B (zh) 2015-10-12 2023-12-01 美商再生元醫藥公司 活化瘦素受體的抗原結合蛋白
MA45801B1 (fr) 2016-11-08 2021-11-30 Regeneron Pharma Protéines de liaison à l'antigène qui sont des antagonistes du récepteur de leptine
SG11202005146VA (en) 2017-12-18 2020-06-29 Regeneron Pharma Bispecific antigen binding molecules that bind leptin receptor and/or gp130, and methods of use thereof
SMT202500283T1 (it) 2018-04-06 2025-09-12 Regeneron Pharma Un anticorpo agonista del recettore della leptina da utilizzare per aumentare la massa ossea in un soggetto affetto da disfunzione metabolica o ipoleptinemia
CN109942716B (zh) * 2019-04-08 2023-05-12 河南师范大学 一种用于治疗代谢疾病的瘦素融合蛋白及其制备方法和应用
CN111848774B (zh) * 2020-08-05 2022-05-10 武汉海特生物制药股份有限公司 一种美曲普汀的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL122818A0 (en) * 1997-07-10 1998-08-16 Yeda Res & Dev Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof
CA2447632C (en) * 2000-06-16 2011-08-02 Asterion Limited Fusion protein agonist comprising a growth hormone binding portion and an external domain of a growth hormone receptor
MX2007001180A (es) * 2004-07-26 2007-04-13 Asterion Ltd Enlazantes.
WO2007080404A2 (en) * 2006-01-12 2007-07-19 Asterion Limited Leptin ligand

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