JP2010534629A5 - - Google Patents
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- Publication number
- JP2010534629A5 JP2010534629A5 JP2010517329A JP2010517329A JP2010534629A5 JP 2010534629 A5 JP2010534629 A5 JP 2010534629A5 JP 2010517329 A JP2010517329 A JP 2010517329A JP 2010517329 A JP2010517329 A JP 2010517329A JP 2010534629 A5 JP2010534629 A5 JP 2010534629A5
- Authority
- JP
- Japan
- Prior art keywords
- alkali metal
- metal salt
- hypochlorous acid
- preparation according
- carrier
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000243 solution Substances 0.000 claims description 7
- XTEGARKTQYYJKE-UHFFFAOYSA-M Chlorate Chemical compound [O-]Cl(=O)=O XTEGARKTQYYJKE-UHFFFAOYSA-M 0.000 claims description 6
- 239000007864 aqueous solution Substances 0.000 claims description 5
- 229910052783 alkali metal Inorganic materials 0.000 claims 8
- -1 alkali metal salt Chemical class 0.000 claims 7
- QWPPOHNGKGFGJK-UHFFFAOYSA-N hypochlorous acid Chemical group ClO QWPPOHNGKGFGJK-UHFFFAOYSA-N 0.000 claims 7
- 238000009472 formulation Methods 0.000 claims 6
- 239000000203 mixture Substances 0.000 claims 6
- 239000013543 active substance Substances 0.000 claims 5
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 4
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 3
- 239000000460 chlorine Substances 0.000 claims 3
- 229910052801 chlorine Inorganic materials 0.000 claims 3
- 239000007788 liquid Substances 0.000 claims 2
- 208000003556 Dry Eye Syndromes Diseases 0.000 claims 1
- 206010013774 Dry eye Diseases 0.000 claims 1
- 239000005708 Sodium hypochlorite Substances 0.000 claims 1
- 150000001340 alkali metals Chemical class 0.000 claims 1
- 230000004888 barrier function Effects 0.000 claims 1
- 239000002876 beta blocker Substances 0.000 claims 1
- 229940097320 beta blocking agent Drugs 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- XTEGARKTQYYJKE-UHFFFAOYSA-N chloric acid Chemical compound OCl(=O)=O XTEGARKTQYYJKE-UHFFFAOYSA-N 0.000 claims 1
- 229940005991 chloric acid Drugs 0.000 claims 1
- 238000004140 cleaning Methods 0.000 claims 1
- 239000006185 dispersion Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 230000002209 hydrophobic effect Effects 0.000 claims 1
- 230000004410 intraocular pressure Effects 0.000 claims 1
- 238000007912 intraperitoneal administration Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- GQPLMRYTRLFLPF-UHFFFAOYSA-N nitrous oxide Inorganic materials [O-][N+]#N GQPLMRYTRLFLPF-UHFFFAOYSA-N 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 125000003259 prostaglandin group Chemical group 0.000 claims 1
- 230000002685 pulmonary effect Effects 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- SUKJFIGYRHOWBL-UHFFFAOYSA-N sodium hypochlorite Chemical compound [Na+].Cl[O-] SUKJFIGYRHOWBL-UHFFFAOYSA-N 0.000 claims 1
- 238000007910 systemic administration Methods 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
- 150000002500 ions Chemical class 0.000 description 2
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 229910001919 chlorite Inorganic materials 0.000 description 1
- 229910052619 chlorite group Inorganic materials 0.000 description 1
- QBWCMBCROVPCKQ-UHFFFAOYSA-N chlorous acid Chemical compound OCl=O QBWCMBCROVPCKQ-UHFFFAOYSA-N 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95203507P | 2007-07-26 | 2007-07-26 | |
| US60/952,035 | 2007-07-26 | ||
| US98818107P | 2007-11-15 | 2007-11-15 | |
| US60/988,181 | 2007-11-15 | ||
| PCT/EP2008/006193 WO2009013019A2 (en) | 2007-07-26 | 2008-07-28 | Pharmaceutical preparations comprising electrochemically activated hypochlorite solutions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010534629A JP2010534629A (ja) | 2010-11-11 |
| JP2010534629A5 true JP2010534629A5 (enExample) | 2015-11-19 |
| JP5872159B2 JP5872159B2 (ja) | 2016-03-01 |
Family
ID=40239573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010517329A Expired - Fee Related JP5872159B2 (ja) | 2007-07-26 | 2008-07-28 | 電気化学的に活性化された次亜塩素酸塩の溶液を含む医薬製剤 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20100266710A1 (enExample) |
| EP (1) | EP2178501B1 (enExample) |
| JP (1) | JP5872159B2 (enExample) |
| KR (2) | KR101733723B1 (enExample) |
| CN (2) | CN101778621B (enExample) |
| AU (1) | AU2008280437B2 (enExample) |
| CA (1) | CA2694929C (enExample) |
| ES (1) | ES2671372T3 (enExample) |
| RU (1) | RU2554802C2 (enExample) |
| WO (1) | WO2009013019A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2374762T1 (sl) | 2010-03-31 | 2013-05-31 | Caliopa Ag | Postroj in postopek za tvorjenje elektrokemično aktivirane raztopine |
| AP2012006545A0 (en) * | 2010-03-31 | 2012-10-31 | Caliopa Ag | Electrochemically activated waterbased solution and use of the solution |
| EP2422792A1 (de) | 2010-08-26 | 2012-02-29 | Caliopa AG | Elektrochemisch aktivierte Lösung auf Wasserbasis und Verwendung der Lösung |
| EP2431056A1 (de) | 2010-09-16 | 2012-03-21 | Caliopa AG | Pharmazeutische Zusammensetzung, enthaltend elektrochemisch aktivierte Salzlösung |
| EP2543359A1 (de) * | 2011-07-08 | 2013-01-09 | Caliopa AG | Gel zur Verwendung in einem Wundbehandlungsmittel |
| EP2567689A1 (en) * | 2011-09-12 | 2013-03-13 | Visiotact Pharma | Ophthtalmic compositions comprising prostaglandin F2 alpha derivatives and hyaluronic acid |
| HK1203068A1 (en) * | 2011-09-16 | 2015-10-16 | Zurex Pharmagra, Llc | Systems and methods for generating germicidal compositions |
| US10617716B2 (en) * | 2014-12-16 | 2020-04-14 | Urgo Us, Inc. | Hypochlorous acid formulations and methods for treating skin conditions |
| WO2018074421A1 (ja) * | 2016-10-21 | 2018-04-26 | ライオン株式会社 | 眼科用剤及び眼科用薬 |
| EP3716764A1 (de) | 2017-11-27 | 2020-10-07 | Sanixtreme Gmbh & Co Kg | Formulierung zur bildung eines desinfizierenden schaums |
| EP3593862A1 (en) | 2018-07-12 | 2020-01-15 | Azad Pharma AG | Electrochemically activated salt solution |
| EP3919047A1 (en) * | 2020-06-03 | 2021-12-08 | AZAD Pharma AG | Microemulsion for the treatment of dry eye syndrome |
| WO2022081297A1 (en) * | 2020-10-12 | 2022-04-21 | The Regents Of The University Of Colorado, A Body Corporate | Compositions and methods for lowering intracranial pressure by intranasal agent administration |
| US20250302868A1 (en) * | 2024-03-26 | 2025-10-02 | Ocusoft, Inc. | Hypochlorous acid-based dry eye formulations |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5693337A (en) * | 1994-07-13 | 1997-12-02 | Wakamoto Pharmaceutical Co., Ltd. | Stable lipid emulsion |
| JPH10236961A (ja) * | 1997-02-25 | 1998-09-08 | Nobel Igaku Kenkyusho:Kk | 電解酸性水を用いた眼科用剤 |
| HK1041600A1 (zh) * | 1998-10-23 | 2002-07-12 | 水基Ip股份有限公司 | 应用杀菌溶液的方法 |
| WO2000033757A1 (en) * | 1998-12-09 | 2000-06-15 | Advanced H¿2?O Inc. | A system for decontamination of dental unit waterlines using electrolyzed water |
| RU2148027C1 (ru) * | 1999-02-01 | 2000-04-27 | Бахир Витольд Михайлович | Способ получения дезинфицирующего раствора - нейтрального анолита анд |
| US7393522B2 (en) * | 2000-01-12 | 2008-07-01 | Novabay Pharmaceuticals, Inc. | Physiologically balanced, ionized, acidic solution and methodology for use in wound healing |
| US6878287B1 (en) * | 2000-02-04 | 2005-04-12 | Radical Waters Ip (Pty) Limited | Dental equipment and method of operating such equipment |
| RU2180605C1 (ru) * | 2000-07-24 | 2002-03-20 | Завод "Автоматика" | Способ внутриушной ультразвуковой терапии хронических средних отитов |
| DE60326226D1 (de) * | 2002-03-21 | 2009-04-02 | Cayman Chemical Co | Prostaglandin f2 alpha analoga in kombination mit einem antimikrobiellen mittel zur behandlung von glaukom |
| US20040191332A1 (en) | 2003-03-27 | 2004-09-30 | Allergan, Inc. | Preserved ophthalmic compositions |
| US20050139808A1 (en) * | 2003-12-30 | 2005-06-30 | Oculus Innovative Sciences, Inc. | Oxidative reductive potential water solution and process for producing same |
| US20050196462A1 (en) * | 2003-12-30 | 2005-09-08 | Oculus Innovative Sciences, Inc. | Topical formulation containing oxidative reductive potential water solution and method for using same |
| KR101319772B1 (ko) * | 2004-11-09 | 2013-10-23 | 노바갈리 파르마 에스 에이 | 면역 억제제를 포함하는 안과용 유제 |
| CA2602411C (en) * | 2005-03-23 | 2015-02-24 | Oculus Innovative Sciences, Inc. | Method of treating second and third degree burns using oxidative reductive potential water solution |
| CA2630816C (en) * | 2005-11-28 | 2014-08-12 | Senju Pharmaceutical Co., Ltd. | Pharmaceutical comprising ppar agonist |
| EP1993572A2 (en) * | 2006-01-20 | 2008-11-26 | Oculus Innovative Sciences, Inc. | Methods of treating or preventing sinusitis with oxidative reductive potential water solution |
-
2008
- 2008-07-28 WO PCT/EP2008/006193 patent/WO2009013019A2/en not_active Ceased
- 2008-07-28 US US12/670,513 patent/US20100266710A1/en not_active Abandoned
- 2008-07-28 CN CN200880025290.8A patent/CN101778621B/zh not_active Expired - Fee Related
- 2008-07-28 KR KR1020157020110A patent/KR101733723B1/ko not_active Expired - Fee Related
- 2008-07-28 ES ES08801496.4T patent/ES2671372T3/es active Active
- 2008-07-28 CA CA2694929A patent/CA2694929C/en not_active Expired - Fee Related
- 2008-07-28 RU RU2010107043/15A patent/RU2554802C2/ru active
- 2008-07-28 CN CN201510507020.2A patent/CN105213299A/zh active Pending
- 2008-07-28 EP EP08801496.4A patent/EP2178501B1/en active Active
- 2008-07-28 KR KR1020107003555A patent/KR101633449B1/ko not_active Expired - Fee Related
- 2008-07-28 JP JP2010517329A patent/JP5872159B2/ja not_active Expired - Fee Related
- 2008-07-28 AU AU2008280437A patent/AU2008280437B2/en not_active Ceased
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